Delivery of FGF18 using mRNA-LNP protects the cartilage against degeneration via alleviating chondrocyte senescence by Keyu Kong, Baixing Li, Yongyun Chang, Chen Zhao, Hua Qiao, Minghao Jin, Xinru Wu, Wenxuan Fan, Liao Wang, Yansong Qi, Yongsheng Xu, Zanjing Zhai, Peixiang Ma, Huiwu Li

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Long-Lasting Anti-Inflammatory Activity of Human Microfragmented Adipose Tissue by Sara Nava, Valeria Sordi, Luisa Pascucci, Carlo Tremolada, Emilio Ciusani, Offer Zeira, Moris Cadei, Gianni Soldati, Augusto Pessina, Eugenio Parati, Mark Slevin, Giulio Alessandri

“…Over the last few years, human microfragmented adipose tissue (MFAT), containing significant levels of mesenchymal stromal cells (MSCs) and obtained from fat lipoaspirate (LP) through a minimal manipulation in a closed system device, has been successfully used in aesthetic medicine as well as in orthopedic and general surgery. Interestingly, in orthopedic diseases, this ready-to-use adipose tissue cell derivative seems to have a prolonged time efficacy even upon a single shot injection into osteoarthritic tissues. …”
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Validity and reliability of the Manchester Oxford Foot Questionnaire (MOXFQ) in one-year postoperative ankle fracture patients—a validation study by Michael Quan Nguyen, Marjolein Memelink Iversen, Knut Harboe, Ingvild Dalen, Aksel Paulsen

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Integrated bioinformatics analysis of the effects of chronic pain on patients with spinal cord injury by Jinlong Zhang, Jinlong Zhang, Longju Qi, Yuyu Sun, Yuyu Sun, Shiyuan Chen, Jinyi Liu, Jiaxi Chen, Fangsu Yan, Wenqi Wang, Qinghua Wang, Liang Chen

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Prepatellar Bursal Infection Caused by Mycobacterium tuberculosis with an In Situ Total Knee Arthroplasty: A Case Report and Comprehensive Literature Review by Abdulrahman D. Algarni

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Peroneal Arteriovenous Fistula and Pseudoaneurysm: An Unusual Presentation by Kevin C. Ching, Kevin M. McCluskey, Abhay Srinivasan

“…Peroneal artery arteriovenous fistulas and pseudoaneurysms are extremely rare with the majority of reported cases due to penetrating, orthopedic, or iatrogenic trauma. Failure to diagnose this unusual vascular pathology may lead to massive hemorrhage or limb threatening ischemia. …”
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Bladder Cancer Invading the Prostate and Penis and Multiple Bone Metastases Showing Significant Improvement after a Short-Term Pembrolizumab Therapy following Radiation and Gemcita... by Kyohei Ishida, Akira Ogose, Gen Kawaguchi, Go Hasegawa, Yohei Ikeda, Noboru Hara, Tsutomu Nishiyama

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Delayed Acute Ischemia as a Consequence of Multi-Ligament Injury of the Left Knee Following a Motorcycle Accident by Laura Leci Tahiri, Lisa Tahiri

“… Motorcycle accidents can cause complex orthopedic and vascular injuries, posing diagnostic and treatment challenges. …”
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Early experiences of patellofemoral arthritis symptoms: A qualitative study in Gujarat, India by Heta R. Patel, M. Balaganapathy, Bipin Serasiya

“…Method: The study was conducted in Gujarat, India, with 14 participants, recruited from regional orthopedic outpatient departments. They were interviewed either in person or online using the Zoom platform, with an expert clinician using a semistructured interview guide in the vernacular language. …”
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The Role of Mesenchymal Stem Cell Secretome (Extracellular Microvesicles and Exosomes) in Animals’ Musculoskeletal and Neurologic-Related Disorders by Alefe Luiz Caliani Carrera, Bruno Watanabe Minto, Patrícia Malard, Hilana dos Santos Sena Brunel

“…Knowing the advances in these modalities and the growing clinical and surgery research and demands for innovations in orthopedic and neurology medicines, this paper aimed to review the literature about the methodologies of use and applications such as the pathways of action and the advances that were postulated for microvesicles and exosomes derived from mesenchymal stem cells in veterinary medicine, especially for musculoskeletal disorders and related injuries.…”
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Pregnancy-Associated Sacroiliitis following an Uncomplicated Pregnancy by Maryam Ahmadi, Farid Abiri, Somaieh Ahmadiani, Ensiyeh Jenabi

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A comparative bio-mechanical performance assessment of additively manufactured bone scaffolds using different beta Ti alloys and Gyroid based cellular structure by Mudassar Rehman, Yanen Wang, Kashif Ishfaq, Ray Tahir Mushtaq, Aqib Mashood Khan, Mohammed Alkahtani, Aamer Nazir, Maimoona Afzal

“…The findings underscore the adaptability of optimized L-PBF settings across biomedical β-Ti alloys, paving the way for advanced patient-specific orthopedic implants.…”
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Effect of miR-144-3p-Targeted Regulation of PTEN on Proliferation, Apoptosis, and Osteogenic Differentiation of Bone Marrow Mesenchymal Stem Cells under Stretch by Shiyong Ling, Xi Luo, Bo Lv, Hua Wang, Mengzhi Xie, Kai Huang, Jingchuan Sun

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A Case of Multiple Phleboliths on the Medial Side of the Right Mandible by Shinichi Sato, Masato Takahashi, Tetsu Takahashi

“…A 66-year-old female patient was admitted to the orthopedic department due to a left femoral neck fracture. …”
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Healthcare Utilization, Costs of Care, and Mortality Among Patients With Spinal Muscular Atrophy by Hiangkiat Tan, Tao Gu, Er Chen, Rajeshwari Punekar, Perry B. Shieh

“…Uses of orthotics/orthoses and orthopedic surgery were frequent: 54.5% and 22.7% childhood group; 27.0% and 38.5% late-onset group. …”
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Rotate-on-Retract Procedural Automation for Robotic-Assisted Percutaneous Coronary Intervention: First Clinical Experience by Arif Al Nooryani, Wael Aboushokka

“…Favorable results in several clinical studies suggest that robotic-assisted PCI may further improve patient outcomes while also benefiting the interventionalist through reduced orthopedic strain and less exposure to ionizing radiation. …”
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Estimating the Physical Properties of Nanofluids Using a Connectionist Intelligent Model Known as Gaussian Process Regression Approach by Tzu-Chia Chen, Ali Thaeer Hammid, Avzal N. Akbarov, Kaveh Shariati, Mina Dinari, Mohammed Sardar Ali

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KL-6 Mucin as Serum Tumor Marker of Metastatic Renal Cancer: A Case Report by Kyohei Ishida, Go Hasegawa, Toshinori Takada, Akira Ogose, Gen Kawaguchi, Yohei Ikeda, Hiroki Nishiyama, Noboru Hara, Tsutomu Nishiyama

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ADVANCEMENTS IN MODERN SURGICAL MANAGEMENT OF TIBIAL PLATEAU FRACTURES: A COMPREHENSIVE REVIEW by Norin Forna, Paul-Dan Sîrbu, Savin Liliana, Lucian Eva, Wilhelm Friedl, Eugen Carata, Tudor Pinteală, Răzvan Tudor, Mihnea Theodor Sîrbu

“…Effective surgical management minimizes the risk of joint instability, enhances long-term prognosis, and maintains the patient’s quality of life. Most orthopedic surgeons adopt a staged treatment strategy, involving initial stabilization followed by definitive surgical fixation, respecting soft tissue conditions, achieving precise anatomical reduction, ensuring stable fixation, and promoting early rehabilitation. …”
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First Description of a Primitive Neuroectodermal Tumor Arising in the Nose by Habib Rizk, Aline Khazzaka, Amer Sebaaly, Maguy Cherfan, Roland Tomb, Riad Sarkis

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