Safety and Feasibility of Repeated Intrathecal Allogeneic Bone Marrow-Derived Mesenchymal Stromal Cells in Patients with Neurological Diseases by Kuang Pan, Lingna Deng, Peiying Chen, Qingxia Peng, Jingrui Pan, Yanfeng Wu, Yidong Wang

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ASA Class Is a Stronger Predictor of Early Revision Risk Following Primary Total Knee Arthroplasty than BMI by Christopher J. Wall, MBBS, BMedSc, FRACS, FAOrthA, Richard N. de Steiger, MBBS, PhD, DipBiomech, FRACS, FAOrthA, Christopher J. Vertullo, MBBS, PhD, FRACS, FAOrthA, Dylan Harries, BSc(Hons), MBiostat, PhD, Srinivas Kondalsamy-Chennakesavan, MBBS, MPH, FRSPH

“…Data from the Australian Orthopaedic Association National Joint Replacement Registry (AOANJRR) were obtained regarding all patients who underwent primary TKA for osteoarthritis in Australia from January 1, 2015, to December 31, 2022. …”
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Medical complexity in emergency and urgent care settings: a scoping review protocol by Diane Lorenzetti, Tanvir C Turin, Sumedh Bele, Eddy Lang, Doreen Rabi, Naomi Popeski, Marie-Claire Uwamahoro, Conne Lategan, Kate Yakubets, Cassandra Chisholm

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Comparison of Percutaneous Transforaminal Endoscopic Surgery (PTES) With MIS-TLIF for Treating Lumbar Degenerative Disease in Obese Patients by Fan W, Chen Y, Zhou T, Xu Y, Gu Y

“…Wenshuai Fan,1,2,* Yuheng Chen,1,* Tianyao Zhou,1 Yun Xu,3,4 Yutong Gu1,4 1Department of Orthopaedic Surgery, Zhongshan Hospital Fudan University, Shanghai, People’s Republic of China; 2Department of Orthopaedics, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People’s Republic of China; 3Centre for Rehabilitation Medicine, Department of Pain Management, Zhejiang Provincial People’s Hospital, Zhejiang, People’s Republic of China; 4Shanghai Southwest Spine Surgery Center, Shanghai, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yutong Gu, Zhongshan Hospital Fudan University, 180 Fenglin Road, Shanghai, 200032, People’s Republic of China, Email 447574313@qq.com Yun Xu, Zhejiang Provincial People’s Hospital, Hangzhou Medical College, Hangzhou, 310014, People’s Republic of China, Email xuyun65204@163.comPurpose: The purpose of this study is to compare clinical outcomes of obese patients with lumbar degenerative disease (LDD) receiving either percutaneous transforaminal endoscopic surgery (PTES) or minimally invasive surgery-transforaminal lumbar interbody fusion (MIS-TLIF).Methods: There were 26 patients underwent PTES, and 29 patients were treated with MIS-TLIF between June 2014 and June 2019. …”
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Implementation of a Cost and Variation Reduction Program for Hemostasis Products at a Large Academic Medical Center: A Multi-Stakeholder Perspective by Shah T, Brethauer S, Danker III WA, Doshi I, O'Hara M, Silber A, Vasileff WK

“…., Raritan, NJ, USA; 3Trinity Life Sciences, Waltham, MA, USA; 4Department of Orthopaedics, Sports Medicine Research Institute, The Ohio State University Wexner Medical Center, Columbus, OH, USACorrespondence: Stacy Brethauer, Email Stacy.Brethauer@osumc.eduGoal: Cost-saving initiatives targeting surgical supplies management have become increasingly common to address rising healthcare costs. …”
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Harnessing natural polymers and nanoparticles: Synergistic scaffold design for improved wound healing by Anitha S, Nandini Robin Nadar, Srividya Shivakumar, Sharma S C, Siddharth P, Surekha Varalakshmi V, Rajesh Lenka, Rajadurai S

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Reduction reactions dominate the interactions between Mg alloys and cells: Understanding the mechanisms by Jua Kim, Jeremy L. Gilbert, William W. Lv, Ping Du, Haobo Pan

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Development and design validation of a novel network meta-analysis presentation tool for multiple outcomes: a qualitative descriptive study by Lehana Thabane, Jason W Busse, Behnam Sadeghirad, Gordon H Guyatt, Mohit Bhandari, Romina Brignardello-Petersen, Fernando Kenji Nampo, Carlos A Cuello-Garcia, Raveendhara R Bannuru, Mark R Phillips, Yu Jia Guo, Sofia Bzovsky

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Novel application of an imageless robotic system in simultaneous unicompartmental knee arthroplasty and anterior cruciate ligament reconstruction by Joshua Yeuk Shun Tran, Rex Wang-Fung Mak, Kevin Ki-Wai Ho, Jonathan Patrick Ng, Cham Kit Wong, Gloria Yan-Ting Lam, Tsz Lung Choi, Michael Tim-Yun Ong, Patrick Shu-Hang Yung

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Novel carbon dots with dual Modulatory effects on the bone marrow and spleen as a potential therapeutic candidate for treating spinal cord injury by Junjin Li, Hongda Wang, Yuanquan Li, Chunzhen Wang, Haiwen Feng, Yilin Pang, Jie Ren, Chuanhao Li, Erke Gao, Dejing Zhang, Dunxu Hu, Pengtian Zhao, Han Ding, Baoyou Fan, Tao Zhang, Xiaomeng Song, Zhijian Wei, Guangzhi Ning, Yong-Qiang Li, Shiqing Feng

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Knockdown of Gfi1 increases BMSCs exosomal miR-150-3p to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axis by Liwen Zheng, Changjie Zhang, Lele Liao, Zhijie Hai, Xin Luo, Haoliang Xiao

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Correlation and diagnostic significance of CD4 T cell subsets and NLRP3 inflammasome in ulcerative colitis: the role of the NLRP3/T-bet/GATA3 axis by Yingnan Hu, Jingyi Tang, Dian Yu, Shuo Su, Jintao Fang, Linying Xia, Wenjun Xu, Weihan Zhu, Ninping Song, Fengyong Wang, Dechang Diao, Wei Zhang

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Amantadine modulates novel macrophage phenotypes to enhance neural repair following spinal cord injury by Shijie Yang, Beibei Yu, Qing Zhang, Yongfeng Zhang, Longhui Fu, Bisheng Zhou, Haining Wu, Jianzhong Li, Shouping Gong

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Robotic Assistance in Simultaneous Bilateral Medial Unicompartmental Knee Arthroplasty: A Retrospective Cohort Study of 126 Knees Demonstrating Enhanced Radiographic Accuracy and C... by Valentina Rossi, MD, Constant Foissey, MD, Andreas Fontalis, MD, MSc, MRCS, Gabriel Gaggiotti, MD, Stefano Gaggiotti, MD, Elvire Servien, MD, PhD, Sébastien Lustig, MD, PhD

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Self-assembled biodegradable herbal-based nanoflower decorative magnesium implants combine therapy with bone regeneration by Huihui Du, Dongdong Zhang, Kui Xue, Limin Ma, Ru Xu, Ji Tan, Feng Peng, Xuanyong Liu

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Remote Continuous Microinjury-Triggered Cytokines Facilitate Severe Diabetic Foot Ulcer Healing via the Ras/Raf/MEK/ERK Pathway by Huang X, Liu J, Wu X, Mo Y, Luo X, Yang Y, Yang C, Liang X, Liang R, Chen Y, Fan Z, Lu W, Chen Y, Hua Q

“…Xiajie Huang,1,2,* Jie Liu,1,* Xiaomei Wu,1 Yangzhou Mo,1 Xiping Luo,1 Yongge Yang,1 Chaoquan Yang,1 Xinyun Liang,1 Rongyuan Liang,1 Yeping Chen,1 Zezhen Fan,1 William Lu,3 Yan Chen,1 Qikai Hua1 1Department of Bone and Joint Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China; 2Collaborative Innovation Centre of Regenerative Medicine and Medical BioResource Development and Application Co-Constructed by the Province and Ministry, Guangxi Medical University, Nanning, People’s Republic of China; 3Department of Orthopaedics and Traumatology, The University of Hong Kong, Hong Kong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yan Chen; Qikai Hua, Department of Bone and Joint Surgery, The First Affiliated Hospital of Guangxi Medical University, Nanning, People’s Republic of China, Email cy003@connect.hku.hk; hqk100@yeah.netPurpose: Microinjury can trigger in situ tissue repair. …”
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One-Step Solid Extraction for Simultaneous Determination of Eleven Commonly Used Anticancer Drugs and One Active Metabolite in Human Plasma by HPLC-MS/MS by Shouhong Gao, Zhengbo Tao, Jingya Zhou, Zhipeng Wang, Yunlei Yun, Mingming Li, Feng Zhang, Wansheng Chen, Yejun Miao

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Prognostic Value of Inflammatory and Nutritional Indicators in Non-Metastatic Soft Tissue Sarcomas by Yan Y, Zhang Y, Chen Y, Zhong G, Huang W, Zhang Y

“…Yuan Yan,1– 3,* Yunhui Zhang,1– 3,* Yonghan Chen,1– 3,* Guoqing Zhong,2,3 Wenhan Huang,2,3 Yu Zhang1– 3 1School of Medicine, South China University of Technology, Guangzhou, Guangdong, People’s Republic of China; 2Department of Orthopaedics Oncology, Guangdong Provincial People’s Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, Guangdong, People’s Republic of China; 3School of Materials Science and Engineering (National Engineering Research Center for Tissue Restoration and Reconstruction), South China University of Technology, Guangzhou, Guangdong, People’s Republic of China*These authors contributed equally to this workCorrespondence: Yu Zhang; Wenhan Huang, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Zhongshan 2nd Road, Guangzhou, Guangdong, People’s Republic of China, Email luck_2001@126.com; wenhanx@126.comBackground: Soft tissue sarcoma (STS) has lacked reliable prognostic indicators. …”
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Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

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PLL-g-HPA Hydrogel Loaded Human Umbilical Cord Mesenchymal Stem Cells Promote Burn Wound Healing in Rat Model by Regulating Inflammation Response by Tian L, Wang Z, Lei T, Feng L, Li Y, Wang K, Zhang Y, Zhang C, Liu J, Xing H, Ren W

“…Linqiang Tian,1,2 Zhaodong Wang,1,2 Tingting Lei,1,3 Lili Feng,1 Yanyan Li,1 Kunxi Wang,1 Yue Zhang,1 Chengshu Zhang,4 Jie Liu,1 Hongxia Xing,3 Wenjing Ren5 1Henan Key Medical Laboratory of Traumatics and Orthopaedics’ Research, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, People’s Republic of China; 2Department of Orthopedics Surgery, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, People’s Republic of China; 3Department of Neurology, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, People’s Republic of China; 4Department of Burn and Plastic Surgery, General Hospital of PINGMEI SHENMA Group, Pingdingshan, People’s Republic of China; 5Clinical Medical Center of Tissue Engineering and Regeneration, Xinxiang Medical University, Xinxiang, People’s Republic of ChinaCorrespondence: Hongxia Xing; Wenjing Ren, Email xhxwh02@163.com; xxmu_rwj@163.comPurpose: Treatment of severe burn wound injury remains a significant clinical challenge as serious infections/complex repair process and irregulating inflammation response. …”
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