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16561
A cost-effectiveness analysis of sotorasib as second-line treatment for patients with KRAS-G12C-mutated metastatic non-small cell lung cancer (mNSCLC) in Switzerland
Published 2025-01-01“…Because the price of sotorasib has not been established in Switzerland, two scenarios were analysed: the first used the published expected monthly United Kingdom (UK) price in Swiss francs (CHF 7870); the second used one-quarter of that price (CHF 1968), according to the lower dose used in the most recent trial, under the condition that one-quarter of the original sotorasib dose is equally effective. Treatment costs of adverse events were included. …”
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16562
Translation and assessment of encultured meaning of the Multi-Dimensional Scale of Perceived Social Support in Diné bizaad (Navajo) using community-based participatory actio...
Published 2025-01-01“…Additional research collaborators included the original developer of the English MSPSS, a researcher with experience in methodology, and a member of the local Navajo community who was a student at the NASNTI. …”
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16563
Persistent Gender and Racial Hierarchies: Marriage Migration and Mixedness in Morocco from the French Protectorate to the Present
Published 2023-07-01“…This interdisciplinary approach combines historic data (primarily from a 1949 study into mixed marriages conducted by the colonial government as well as magazines, novels and memoirs) with 52 anthropological semi-structured interviews (conducted in Morocco between 2018 and 2022) with children of mixed couples and some of their parents.We examine first how the demographic make-up of mixed couples and where they choose to settle has shifted, looking at their gender split, their countries of origin, their occupations and where they met. This has diversified considerably throughout the 20th century: the individuals come from a much larger number of countries (no longer primarily Moroccan soldiers who returned from France with French women) and Moroccan women are now more likely to travel abroad. …”
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16564
Evolution of human genes encoding cell surface receptors involved in the regulation of appetite: an analysis based on the phylostratigraphic age and divergence indexes
Published 2023-12-01“…A large number of exogenous ligands of various origins, including drugs, are known for cell surface receptors, which accounts for interest in them from biomedical researchers. …”
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16565
Socio-economic assessment of drought impacts in Lesotho: implications for early action
Published 2024-11-01“…Future humanitarian and policy interventions to prepare for droughts can use this evidence to identify the type of support that would be the most well-received by community members who are preparing for long-term drying trends in their region. Originality/value – The study presents an understanding of people’s opinions of the nature and state of drought impacts, which are key to any effort towards developing and implementing relevant anticipatory action interventions to minimise the impacts of drought.…”
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16566
Immunohistochemical Expression of p53 Gene and Clinicopathological Assessment of Low-grade Serous Ovarian Cancer and High-grade Serous Ovarian Cancer: A Cohort Study
Published 2024-12-01“…More than 85-90% of ovarian cancer cases originates from epithelial causes. Dysfunctional p53 is a hallmark of many cancers, including ovarian cancer. …”
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16567
Community-based models of care for management of type 2 diabetes mellitus among non-pregnant adults in sub-Saharan Africa: A scoping review.
Published 2023-01-01“…This model reported a higher linkage and engagement in care at 9 months compared to the corresponding facility model, but only slight reductions of average blood glucose levels at six months compared to baseline. 2) A facility-originated community model where after treatment initiation, a substantial part of follow-up was offered at community level. …”
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16568
The Exordium of Adébáyọ̀ Fálétí’s Poetry
Published 2021-12-01“…Four of the eleven narrative poems, (‘Ẹ̀là Lọrọ̀ ’, ‘̀ Ṣàṣọrẹ’, ‘Alágbára Ilé àti Alágbára Oko’, and ‘Agbódóro ́ - gun’) are adapted from the Ifá corpus and there are strong evidences that ìjálá (Ogun poetry/hunter’s) is the original source of the story retold in ‘Adébímpé Ojẹ̀dòkun’. …”
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16569
Deep learning-based synthetic CT for dosimetric monitoring of combined conventional radiotherapy and lattice boost in large lung tumors
Published 2025-01-01“…Dosimetric parameters of all OARs were significantly higher than those in the original treatment plan (P < 0.01). The sCT based adaptive LRT boost plan, when combined with CRT, significantly reduced the dose to OARs compared to CRT alone (P < 0.05). …”
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16570
The Self-Defence Scroll of Kyokushinkai Karate: Analysing the Mokuroku Ōyama Masutatsu Received from Daitō-ryū Aikijūjutsu Master Yoshida Kōtarō
Published 2025-01-01“…The research gives a full analysis of Kyokushinkai self-defence techniques, which can be found in the original and revised editions of What is Karate?, This is Karate, Advanced Karate, and Mas Oyama’s Essential Karate, written by the founder of Ōyama Masutatsu himself, as well as Kyokushin Karate Self-Defense Techniques by high-ranking Kyokuhsinkai practitioner Bobby Lowe. …”
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16571
Un programme d’éducation à l’environnement en RDC : la malle pédagogique « les grands singes et leur habitat », présentation des résultats d’une campagne de sensibilisation en pays...
Published 2014-01-01“…Les menaces sur cet habitat et sur cette espèce endémique sont toutes d’origine anthropique. L’éducation à l’environnement en sensibilisant les populations locales à leurs rôles dans la conservation apparaît comme un moyen de protéger ces écosystèmes. …”
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16572
Results of replacing fish meal with insect protein in carp feeds
Published 2024-12-01“…At the same time, a tendency for an increase in hemoglobin content and the count of erythrocytes in the blood of the experimental group compared to the control group was recorded. Originality.For the first time, the effectiveness of full or partial replacement of fish meal in carp feeds with black soldier fly meal was investigated according to a comprehensive analysis of productive, individual physiological and biochemical parameters of the fish body in the experimental groups. …”
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16573
Ekstraksi Knowledge tentang Penyebaran #Ratnamiliksiapa pada Jejaring Sosial (Twitter) menggunakan Social Network Analysis (SNA)
Published 2019-12-01“…The results of this research are the researcher had found the three key actors (creator and influencers) which originated from 5 main actors who spread #RatnaMilikSiapa tweet. …”
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16574
The impact of attitude towards an e-tax system on tax compliance of Vietnamese enterprises: Adoption of an e-tax system as a mediator
Published 2022-01-01“…Besides, the research is conducted in the context of Vietnam, thus, it is a reference for studies in other developing countries having a similar economy or tax administration. ORIGINALITY/VALUE: This study contributes to enhancing research associated with tax compliance, especially investigating the mediating impact of adoption of an e-tax system in the association between attitude towards an e-tax system and tax compliance of enterprises in the context of Vietnam. …”
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16575
Profil Penderita Penyakit Tuberkulosis Paru BTA Positif yang Ditemukan di BP4 Lubuk Alung periode Januari 2012 – Desember 2012
Published 2014-05-01“…Most are 21-30 years of age 23.2%. The area of origin mostly from Kab. Padang Pariaman 29.4%. The degree of sputum smear positivity mostly positive three (+3) was 44.2%. …”
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16576
Magnetic hybrid chitin-horse manure humic acid for optimized Cd(II) and Pb(II) adsorption from aquatic environment
Published 2025-06-01“…Based on Brunauer, Emmett, and Teller's (BET) theory, the HMHA-Ch-Fe3O4 specific surface area (52.26 m2/g) was higher than original HMHA (35.71 m2/g). The average pore size of HMHA-Ch-Fe3O4 (7.33 nm) was within the mesoporous range (2–50 nm). …”
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16577
Non-small Cell Lung Cancer Cell Line PC-9 Drug-resistant Mutant Cell Line Establishment and Validation of Their Sensitivity to EGFR Inhibitors
Published 2024-11-01“…Methods Clustered regularly interspaced short palindromic repeats/CRISPR-associated nuclease 9 (CRISPR/Cas9) technology was employed to knock in the EGFRT790M/C797S mutant fragment into NSCLC PC-9 cells, originally harboring the EGFRD19 mutation, to generate the PC-9 EGFRD19/T790M/C797S cell model. …”
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16578
Assessing and Enhancing Nutrition and Physical Activity Environments in Early Childhood Education and Care Centers: Scoping Review of eHealth Tools
Published 2025-01-01“…The tools identified in the gray literature originated in Canada (4 tools, 57%) and the United States (3 tools, 43%). …”
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16579
Evaluating the Cellophane Production Supply Chain Using Multi-Criteria Decision-Making Approaches
Published 2024-07-01“…Such efforts aim to safeguard the environment and uphold accountability. Originality/value: This study presented a comprehensive analysis and optimization of the cellophane supply chain using ISM and MCDM approaches. …”
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16580
Les vestiges fauniques de la rue Lecointre à Reims/Durocortorum : une carrière utilisée comme dépotoir
Published 2022-11-01“…As the quarry is situated in an outlying sector, undergoing rapid change, the atypical composition of the bone remains found therein raises the question of the origin of this waste material. The answer is likely to be found in the monumental ensembles near the quarry, such as the polygonal temple and the amphitheater, located, respectively, 50 and 120 m from the quarry. …”
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