Equine piroplasmosis in different geographical areas in France: Prevalence heterogeneity of asymptomatic carriers and low genetic diversity of Theileria equi and Babesia caballi by Maggy Jouglin, Claire Bonsergent, Nathalie de la Cotte, Mickaël Mège, Céline Bizon, Anne Couroucé, Élodie-Anne Lallemand, Agnès Leblond, Louise C Lemonnier, Aurélia Leroux, Ilaria Marano, Alexandre Muzard, Émilie Quéré, Marion Toussaint, Albert Agoulon, Laurence Malandrin

“…Notably, two of the four T. equi genotype A isolates were detected in horses originating from Spain. All 19 B. caballi isolates belonged to the genotype A.The discussion section explores the link between these results, the tick distribution and abundance, and the frequency of detection of T. equi and B. caballi in febrile cases attributed to piroplasmosis.…”
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Herbal HuoXueTongFu Formula with anti-inflammatory and fibrinolytic activity regulation for the prevention of postoperative peritoneal adhesions by Lili Yang, Lili Yang, Yali Wang, Yali Wang, Zhengjun Li, Zhengjun Li, Wen Li, Yanqi Chen, Ziyang Kong, Huixiang Zhang, Jiafei Wu, Mingqi Shang, Ming Li, Yaoyao Bian, Yaoyao Bian, Yaoyao Bian, Li Zeng, Li Zeng

“…BackgroundThe HuoXueTongFu Formula (HXTF) originates from the classic prescription “DaHuangMuDan Decoction” from the “Synopsis of the golden chamber”. …”
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Nomograms for predicting recurrence of HER2‐positive breast cancer with different HR status based on ultrasound and clinicopathological characteristics by Xudong Zhang, Hanqing Kong, Xiaoxue Liu, Qingxiang Li, Xinran Fang, Junjia Wang, Zihao Qin, Nana Hu, Jiawei Tian, Hao Cui, Lei Zhang

“…Eighty percent of the original samples from HR−/HER2+ and HR+/HER2+ patients were extracted by bootstrap sampling as the training cohorts, while the remaining 20% were used as the external validation cohorts. …”
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Extracellular vesicles, RNA sequencing, and bioinformatic analyses: Challenges, solutions, and recommendations by Rebecca T. Miceli, Tzu‐Yi Chen, Yohei Nose, Swapnil Tichkule, Briana Brown, John F. Fullard, Marilyn D. Saulsbury, Simon O. Heyliger, Sacha Gnjatic, Natasha Kyprianou, Carlos Cordon‐Cardo, Susmita Sahoo, Emanuela Taioli, Panos Roussos, Gustavo Stolovitzky, Edgar Gonzalez‐Kozlova, Navneet Dogra

“…Circulating EVs carry functional small RNAs and other molecular footprints from their cell of origin, and thus have evident applications in liquid biopsy, therapeutics, and intercellular communication. …”
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Study on stress corrosion behavior and failure mechanism of galvanized bolts in complex coal mine environments by Zhe He, Nong Zhang, Zhengzheng Xie, Chao Ma, Changliang Han, Fan Zhang, Huiqing Wang, Saad S. Alarifi

“…Among them, the coated bolts largely maintained their original mechanical properties and had the best anti-corrosion capability. …”
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Spatial and single-cell transcriptomics reveal cellular heterogeneity and a novel cancer-promoting Treg cell subset in human clear-cell renal cell carcinoma by Lijuan Wang, Qian He, Weijun Qin, Xiyu Song, Yumeng Zhu, Wenwen Geng, Jianhua Jiao, Hongjiao Liu, Ruo Chen, Xiuxuan Sun, Jiejie Geng, Zhinan Chen

“…In addition, we traced the origin of IL-1β+ Treg cells and revealed that IL-18 can induce the expression of IL-1β in Treg cells via the ERK/NF-κB pathway.Conclusions We demonstrated a novel cancer-promoting Treg cell subset and its interactions with MRC1+FOLR2+TAMs, which provides new insight into Treg cell heterogeneity and potential therapeutic targets for ccRCC.…”
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Synaptotagmin-1 attenuates myocardial programmed necrosis and ischemia/reperfusion injury through the mitochondrial pathway by Teng Sun, Jialei Li, Shuang Wang, Yu Han, Xiangyu Tao, Min Yuan, Zhijie Jing, Ting Liu, Yuehong Qi, Siqi Liu, Yanlin Feng, Jiasong Chang, Lan Zhou, Lijuan Gao, Jianyun Shi, Ruihong Ning, Jimin Cao

“…Synaptotagmin-1 (Syt1), a Ca2+ sensor, is originally identified in nervous system and mediates synchronous neurotransmitter release. …”
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Maternal seafood intake, dietary contaminant exposure, and risk of juvenile idiopathic arthritis: exploring gene-environment interactions by Vilde Øverlien Dåstøl, Vilde Øverlien Dåstøl, Kristine Løkås Haftorn, Hamid Khoshfekr Rudsari, Piotr Pawel Jaholkowski, Piotr Pawel Jaholkowski, Ketil Størdal, Ketil Størdal, Siri Eldevik Håberg, Siri Eldevik Håberg, Clarice R. Weinberg, Lisa G. Rider, Ole A. Andreassen, Ole A. Andreassen, Ole A. Andreassen, Anne Lise Brantsæter, Ida Henriette Caspersen, Ida Henriette Caspersen, Helga Sanner, Helga Sanner

“…ObjectivesJuvenile idiopathic arthritis (JIA) originates from a complex interplay between genetic and environmental factors. …”
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Analysis of ecological network evolution in an ecological restoration area with the MSPA-MCR model: A case study from Ningwu County, China by Ziyan Guo, Chuxin Zhu, Xiang Fan, Muye Li, Nuo Xu, Yuan Yuan, Yanjun Guan, Chunjuan Lyu, Zhongke Bai

“…With the expansion of the area, the original 6 ecological source patches merged into 4 in 2010 and then 3 in 2020, and 1 new patch emerged in 2010 and 5 more patches in 2020. (2) The area of high ecological resistance showed a minor increase from 2000 (576.90 km2) to 2010 (592.31 km2), but then declined sharply by 38.53 % in 2020 (364.07 km2). (3) With the emergence of new ecological source patches, more corridors were needed to connect them. …”
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Satisfaction and Preferences for Infusion Therapies in Advanced Parkinson’s Disease—Patient Perspective by Julia Węgrzynek-Gallina, Tomasz Chmiela, Michał Borończyk, Aleksandra Buczek, Patrycja Hudzińska, Hubert Bigajski, Damian Waksmundzki, Justyna Gawryluk, Joanna Siuda

“…<i>Results:</i> Among the original cohort of 64 patients, 50 completed the survey, including 31 who might choose between infusion therapies. …”
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PRMT5 inhibition has a potent anti-tumor activity against adenoid cystic carcinoma of salivary glands by Vasudha Mishra, Alka Singh, Michael Korzinkin, Xiangying Cheng, Claudia Wing, Viktoria Sarkisova, Ashwin L. Koppayi, Alexandra Pogorelskaya, Oksana Glushchenko, Manu Sundaresan, Venkat Thodima, Jack Carter, Koichi Ito, Peggy Scherle, Anna Trzcinska, Ivan Ozerov, Everett E. Vokes, Grayson Cole, Frank W. Pun, Le Shen, Yuxuan Miao, Alexander T. Pearson, Mark W. Lingen, Bruce Ruggeri, Ari J. Rosenberg, Alex Zhavoronkov, Nishant Agrawal, Evgeny Izumchenko

“…Abstract Background Adenoid cystic carcinoma (ACC) is a rare glandular malignancy, commonly originating in salivary glands of the head and neck. …”
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Cisplatin resistance alters ovarian cancer spheroid formation and impacts peritoneal invasion by Lydia C. Powell, Marcos Quintela, David W. James, Emenike Onyido, David Howard, Kadie Edwards, Jordan L. Turney, Charlotte R. Morgan, Jenny Worthington, Nicole Williams, Alexander Dulebo, Heiko Haschke, Deyarina Gonzalez, R. Steven Conlan, Lewis W. Francis

“…EOC metastasis commonly occurs through the extensive dissemination of multicellular aggregates, formed of cells originally shed from the primary ovarian tumour, within the peritoneal cavity. …”
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Adipose tissue may not be a major player in the inflammatory pathogenesis of Autism Spectrum Disorder by Baojiang Wang, Yueyuan Qin, Yong Chen, Xiujie Zheng, Yanjuan Chen, Juan Zhao, Feng Zhang, Shan Duan

“…Conclusions: Our findings suggest that inflammation in ASD likely originates from non-adipocyte sources, implying that adipose tissue may not play a major role in inflammatory pathogenesis of ASD. …”
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Comparative analysis of feeding strategies and post mortem aging time on the oxidative status and color of the longissimus thoracis et lumborum muscle in Braford steers by María Sofía Castaño Ledesma, Gustavo Adolfo Palma, Gustavo Adolfo Palma, Claudio Darío Borsarelli, Claudio Darío Borsarelli, María Sumampa Coria, María Sumampa Coria

“…Several colorimetric assays were employed to evaluate the antioxidant capacity of both enzymatic and non-enzymatic origin, as well as the levels of protein and lipid oxidation. …”
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NORDIC denoising on VASO data by Lasse Knudsen, Lasse Knudsen, Luca Vizioli, Federico De Martino, Lonike K. Faes, Daniel A. Handwerker, Steen Moeller, Peter A. Bandettini, Peter A. Bandettini, Laurentius Huber

“…This method, known as laminar fMRI, is inherently signal-to-noise ratio (SNR)-limited, especially at lower field strengths, with the dominant noise source being of thermal origin. Furthermore, laminar fMRI is challenged with signal displacements due to draining vein effects in conventional gradient-echo blood oxygen level-dependent (BOLD) imaging contrasts. fMRI contrasts such as cerebral blood volume (CBV)-sensitive vascular space occupancy (VASO) sequences have the potential to mitigate draining vein effects. …”
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Molecular and biological characterization of infectious full-length cDNA clones of two viruses in Paris yunnanensis, including a novel potyvirus by Pingxiu Lan, Peng He, Aiqiu Mu, Mengji Cao, Yun Wang, Guohua Zhou, Xiaojiao Chen, Hong Cai, Fan Li

“…A total of 179 field P. yunnanensis leaf samples from four counties in 2020–2021, and all 640 P. yunnanensis plants from a whole study plot of Lijiang in 2024, were tested using RT-PCR and specific primers, the results showed that PpCMV is a potential preponderant species in some regions, and ParPV-5 has the possible transmission from the original site to other regions.…”
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Impacts of Sandstorms on Chemistries of Ambient PAHs in a Small City in North China by Zhiyong Li, Zhen Zhai, Jixiang Liu, Lan Chen, Zhuangzhuang Ren, Chen Liu, Ziyi Zhan, Ziyuan Yue, Wenjia Zhu, Jihong Wei, Huiying Gao, Songtao Guo

“…Potential source contribution function (PSCF) indicated that OLC partly came from sandstorm origin area–Inner Mongolia. Low diagnostic ratios of FA/(FA + PY) in the SSP also indicated OLC was more important. …”
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Impact of infection in patients with non-ST elevation acute coronary syndrome undergoing percutaneous coronary intervention: insight from a multicentre observational cohort from Ch... by Jun Li, Lei Jiang, Wei Chen, Ning Tan, Wei Guo, Ji-yan Chen, Yuan-hui Liu, Peng-cheng He, Peng-Yuan Chen, Chong-Yang Duan, Xue-Biao Wei, Yin-Lin Zhou, Zhu-Jun Chen, Jian-Fang Luo, Dan-Qing Yu, Qing-Shan Geng, Chun-Ying Lin, Zhi-Qiang Guo, Yan-Song Guo, Yi-Yue Chen, Wen-Sheng Li

“…Objective We aimed to describe the association between in-hospital infection and prognosis among patients with non-ST elevation acute coronary syndrome (NSTE-ACS) who received percutaneous coronary intervention (PCI).Design This observational cohort originated from a database of patients with NSTE-ACS who underwent PCI from 1 January 2010 to 31 December 2014.Setting Five centres in South China.Participants This multicentre observational cohort study consecutively included 8197 patients with NSTE-ACS who received PCI. …”
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Pushing the Atacama Large Millimeter/submillimeter Array to the Limit: 140 pc Resolution Observations of a z = 6.6 Quasar–Galaxy Merger Resolve Strikingly Different Morphologies of... by Romain A. Meyer, Bram Venemans, Marcel Neeleman, Roberto Decarli, Fabian Walter

“…We find that dust continuum is emitted in regions of $\unicode{x0007E}0^{\prime\prime} \,.02-0^{\prime\prime} \,.04$ consistent with the size of photodissociation regions (PDRs), whereas 50% of the [C ii ] originates from larger physical scales ( θ ≳ 2″). The large-scale [C ii ] emission presents a velocity gradient aligned with a nearby companion with perturbed kinematics, and misaligned with the kinematics of the small-scale emission. …”
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Molecular Phylogenetics and Estimation of Evolutionary Divergence and Biogeography of the Family Cordycipitaceae (Ascomycota, Hypocreales) by Huili Pu, Jiao Yang, Nemat O. Keyhani, Lixia Yang, Minhai Zheng, Chenghao Qiu, Yuchen Mao, Junya Shang, Yongsheng Lin, Chengjie Xiong, Longbing Lin, Pengyu Lai, Yanbin Huang, Xin Yuan, Huiling Liang, Longfei Fan, Xiaoli Ma, Chunjin Qiu, Junzhi Qiu

“…The historical biogeography of <i>Akanthomyces sensu lato</i> was reconstructed using reconstructing ancestral state in phylogenies (RASP) analysis, indicating that it most likely originated in Asia. Combined morphological characterization and phylogenetic analyses were used to identify and taxonomically place five species within Cordycipitaceae. …”
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