Inducing aggresome and stable tau aggregation in Neuro2a cells with an optogenetic tool by Shigeo Sakuragi, Tomoya Uchida, Naoki Kato, Boxiao Zhao, Toshiki Takahashi, Akito Hattori, Yoshihiro Sakata, Yoshiyuki Soeda, Akihiko Takashima, Hideaki Yoshimura, Gen Matsumoto, Hiroko Bannai

“…Tauopathy is a spectrum of diseases characterized by fibrillary tau aggregate formation in neurons and glial cells in the brain. Tau aggregation originates in the brainstem and entorhinal cortex and then spreads throughout the brain in Alzheimer’s disease (AD), which is the most prevalent type of tauopathy. …”
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Mercury Vapour Long-Lasting Exposure: Lymphocyte Muscarinic Receptors as Neurochemical Markers of Accidental Intoxication by E. Roda, A. Giampreti, S. Vecchio, P. Apostoli, T. Coccini

“…A 72-year-old man with polyneuropathy of suspected toxic origin. At hospitalization, toxicological clinical evaluations confirmed the altered neurological picture documented across the last decade. …”
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Exploration of Digital Twin Design Mechanism of the Deep in Situ Rock Insulation Coring Device by Bo Yu, Heping Xie, Ling Chen, Wu Zhao, Zhiqiang He

“…It is significant to keep the original appearance of the core and obtain the in situ core for the analysis of deep geological fluid and the exploration of the law of geological disasters caused by large-scale geological exploitation. …”
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Pathogenicity of tick-derived lymphocytic choriomeningitis virus in BALB/c mice by Ziyan Liu, Xiaojie Liang, Liang Li, Ning Liu, Zedong Wang, Feng Wei

“…A total of 16 amino acid substitutions were identified in the L, Z, and GPC proteins between the original JX14 strain and the strain obtained after six months of infection in BALB/c mice. …”
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Autoencoder Reconstruction of Cosmological Microlensing Magnification Maps by Somayeh Khakpash, Federica B. Bianco, Georgios Vernardos, Gregory Dobler, Charles Keeton

“…Even though we observe a mild loss of resolution in the generated maps, we find this effect to be smaller than the smoothing effect of convolving the original map with a source of a plausible size for its accretion disk in the red end of the optical spectrum and larger wavelengths and particularly one suitable for studying the broad-line region of quasars. …”
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Chalcogenide perovskites: enticing prospects across a wide range of compositions and optoelectronic properties for stable photodetector devices by Shilpa Mariam Samuel, Sadasivan Shaji, David Avellaneda Avellaneda, Bindu Krishnan

“…Recently, metal halide perovskites have demonstrated groundbreaking photodetector performance due to their exceptional properties originating from their perovskite structure. However, toxicity and stability remain challenges for their large-scale applications. …”
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Actively protective combinatorial analysis: A scalable novel method for detecting variants that contribute to reduced disease prevalence in high-risk individuals by J Sardell, S Das, K Taylor, C Stubberfield, A Malinowski, M Strivens, S Gardner

“…The results support the mechanism of action hypotheses identified in our original causative disease analyses. They also illustrate the potential for development of precision medicine approaches that can increase healthspan by reducing the progression of disease.…”
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Failure mechanics mechanisms and permeability stage evolution of limestone considering wave velocity and failure surface characteristics by Genshui Wu, Weijian Yu, Bao Pan, Chuangfeng Fang, Hanxiao Guo, Chao Zhang

“…The results demonstrate that the original cracks in thin limestone are more developed and have a gully-like structure at the mesoscopic scale than those in Ordovician limestone. …”
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A transgenic cell line with inducible transcription for studying (CGG)n repeat expansion mechanisms by I. V. Grishchenko, A. A. Tulupov, Y. M. Rymareva, E. D. Petrovskiy, A. A. Savelov, A. M. Korostyshevskaya, Y. V. Maksimova, A. R. Shorina, E. M. Shitik, D. V. Yudkin

“…One type of the cell lines contains an exogenous repeat integrated into the genome by the Sleeping Beauty transposon; in another cell line, the vector is maintained as an episome due to the SV40 origin of replication. These experimental systems can serve for f inding the causes of instability and the development of therapeutic agents. …”
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Prevalence and impact of pelvic floor dysfunctions on quality of life in women 5–10 years after their first vaginal or caesarian delivery by Alba González-Timoneda, Nerea Valles-Murcia, Paula Muñoz Esteban, María Sol Torres López, Elisa Turrión Martínez, Patxi Errandonea Garcia, Lola Serrano Raya, Francisco Nohales Alfonso

“…However, recent evidence addressing its multifactorial origin is scant. Objective: Our aim was to investigate late prevalence, risk factors, and the impact on quality of life of PFD in women after their first vaginal or caesarian birth. …”
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Novel Haplotype Indicator for End-Stage Renal Disease Progression among Saudi Patients by Cyril Cyrus, Shahanas Chathoth, Chittibabu Vatte, Nafie Alrubaish, Othman Almuhanna, J. Francis Borgio, Samir Al-Mueilo, Fahd Al Muhanna, Amein K. Al Ali

“…A total of 160 CKD patients and 189 control subjects of Saudi origin participated in the study. Eight polymorphisms (SHROOM3-rs9992101, rs17319721; SLC7A9-rs4805834; MYH9-rs4821480, rs4821481, rs2032487, rs3752462; CST3-rs13038305) were genotyped using TaqMan assay, and the haplotype analysis was done using the HaploView 4.2 software. …”
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Pengaruh Gaya Kepemimpinan Situasional, Motivasi dan Kompensasi Terhadap Produktivitas Kerja Karyawan by Yuni Pratikno, Bambang Nurakhim, Eric Hermawan, Maulana Arief Rachman Hakim

“…Conclusion: These findings can be a reference in making policies for companies to increase compensation so that work productivity increases. Originality/value (State of the art): This study helps organizations understand the importance of adapting leadership styles to suit employee needs in order to increase productivity. …”
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Enhancing decay resistance and maintaining quality of stored apples (Malus domestica ‘Golden Delicious’) through essential oil-enriched edible coatings by Atiyeh Oraee, Yahya Selahvarzi, Mona Ghazimoghadam, Bahram Abedy, Mohammad Ali Sabokkhiz

“…Research limitations: Thyme essential oil (EO) has limitations when used directly, inculding its strong odor and flavor, low stability, low water solubility, and high volatility. Originality/Value: Overall, ALV and ZMO edible coatings appear to be a viable solution for suppressing fungal infections while maintaining apple quality under both situations.…”
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Clinical course of patients relisted for orthotopic heart transplantation: A national study by David Rekhtman, BS, Amit Iyengar, MD, MSE, Nikhil Ganjoo, BA, Cindy Song, BA, Noah Weingarten, MD, Max Shin, MD, Michaela Asher, MPhil, John DePaolo, MD, PhD, Marisa Cevasco, MD, MPH, Pavan Atluri, MD

“…Patients delisted from their original transplant center due to relisting at another center were identified. …”
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Physics-driven Explosions of Stripped High-mass Stars: Synthetic Light Curves and Spectra of Stripped-envelope Supernovae with Broad Light Curves by Jing Lu, Brandon L. Barker, Jared Goldberg, Wolfgang E. Kerzendorf, Maryam Modjaz, Sean M. Couch, Joshua V. Shields, Andrew G. Fullard

“…Stripped-envelope supernovae (SESNe) represent a significant fraction of core-collapse supernovae, arising from massive stars that have shed their hydrogen and, in some cases, helium envelopes. The origins and explosion mechanisms of SESNe remain a topic of active investigation. …”
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Detection and interpretation of the time-varying seasonal signals in China with multi-geodetic measurements by Liansheng Deng, Yugang Xiao, Qusen Chen, Wei Peng, Zhao Li, Hua Chen, Zhiwen Wu

“…The results reveal that all CMONOC time series exhibit seasonal signals characterized by amplitude and phase modulations, and the SSA method outperforms the traditional least squares fitting (LSF) method in extracting and interpreting the time-varying seasonal signals from the original time series. The decrease in the root mean square (RMS) correlates well with the annual cycle variance estimated by the SSA method, and the average reduction in noise amplitudes is nearly twice as much for SSA filtered results compared with those from the LSF method. …”
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Observations of Loki Patera by Juno during Close Flybys by Alessandro Mura, Rosaly M. C. Lopes, Federico Tosi, Francesca Zambon, Roberto Sordini, Peter J. Mouginis-Mark, Julie Rathbun, Scott Bolton, Jani Radebaugh, Alberto Adriani, Andrea Cicchetti, Davide Grassi, Melissa Mirino, Raffaella Noschese, Giuseppe Piccioni, Christina Plainaki, Giuseppe Sindoni

“…Data collected in 2024 may indicate the onset of a new resurfacing wave originating from a point source, rather than the foundering of a linear section of the crust. …”
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Spatiotemporal dynamics of early oogenesis in pigs by Wei Ge, Yi-Lin Niu, Yu-Kang Li, Li Li, Han Wang, Wen-Wen Li, Tian Qiao, Yan-Ni Feng, Yu-Qing Feng, Jing Liu, Jun-Jie Wang, Xiao-Feng Sun, Shun-Feng Cheng, Lan Li, Wei Shen

“…RNA velocity analysis with ST identifies the molecular characteristics and spatial dynamics of granulosa cell lineages originating from the cortical and medullary regions in pig ovaries. …”
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Development of Genomic SSR Markers for Assessing Genetic Diversity in Korean Native <i>Fallopia multiflora</i> by Raveendar Sebastin, Ki Hyun Kim, Hye Ran Shin, Jin-Tae Jeong, Ju-Kyung Yu, Yoon-Sup So, Jong-Wook Chung

“…However, there is still confusion about the botanical origin of the species and the phylogenetic relationship between the cultivars and the wild relatives. …”
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Dimensional control of interface coupling-induced ferromagnetism in CaRuO3/SrCuO2 superlattices by Li Zhe, Shi Wenxiao, Zhang Jine, Zheng Jie, Wang Mengqin, Zhu ZhaoZhao, Han Furong, Zhang Hui, Xie Liming, Yunzhong Chen, Fengxia Hu, Baogen Shen, Yuansha Chen, Jirong Sun

“…The Hall and magnetoresistance measurements indicate the appearance of an interfacial FM state in the originally paramagnetic CaRuO3 layers when the CaRuO3 layer is in proximity to the chain-type SrCuO2 layers; this superlattice has the highest Curie temperature of ~75 K and perpendicular magnetic anisotropy. …”
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