Rational engineering of minimally immunogenic nucleases for gene therapy by Rumya Raghavan, Mirco J. Friedrich, Indigo King, Samuel Chau-Duy-Tam Vo, Daniel Strebinger, Blake Lash, Michael Kilian, Michael Platten, Rhiannon K. Macrae, Yifan Song, Lucas Nivon, Feng Zhang

“…However, cellular and humoral immunogenicity of genome editing tools, which originate from bacteria, complicates their clinical use. …”
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Interaction Prediction Optimization in Multidisciplinary Design Optimization Problems by Debiao Meng, Xiaoling Zhang, Hong-Zhong Huang, Zhonglai Wang, Huanwei Xu

“…IPM is utilized for controlling subsystems and coordinating the produce process in large-scale systems originally. We combine the strategy of IPM with CO and propose the Interaction Prediction Optimization (IPO) method to solve MDO problems. …”
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Chemical evolution characteristics and influencing factors of groundwater in the saline and fresh water funnel area in Hengshui City, North China by Yanbo Yu, Baizhong Yan, Yapeng Tuo, Xinkai Zhan, Xiandong Xie

“…The results showed that: With the exception of the deep freshwater funnel area in the western region, which exhibits a trend of water quality deterioration (Cl− accounted for more than 25%), groundwater quality in the other funnel areas demonstrates an improving trend (HCO $$_{3}^{-}$$ accounted for more than 25%). The origins of hydrochemical components in the groundwater of the two types of funnel areas are influenced by rock weathering. …”
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“…Wordwall is quite easy”: Students’ perceptions of using online platforms as English learning media by Putri Kurniawan Aprilia, Dwi Fita Heriyawati, M. Galuh Elga Romadhon, Zalsa Febrina Syabilla

“…This software offered a variety of original and engaging English language learning games. …”
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An Interactive Database of Cocaine-Responsive Gene Expression by Willard M. Freeman, Kathryn E. Dougherty, Sally E. Vacca, Kent E. Vrana

“…Accompanying each gene is a description of the gene, links to the original publications, and a link to the appropriate OMIM (Online Mendelian Inheritance in Man) entry. …”
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Towards the decolonization of the extractive regime: Patterns and limits of judicialization in mining conflicts by María Ximena González-Serrano, Digno José Montalván-Zambrano, Lieselotte Viaene

“…Our analysis draws on theoretical references from the field of strategic litigation, the origins of international law and decolonial studies. …”
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Animal Bones Char Solubilization by Gel-Entrapped Yarrowia lipolytica on Glycerol-Based Media by Maria Vassileva, Bettina Eichler-Lobermann, Antonia Reyes, Nikolay Vassilev

“…Simultaneous solubilization of hydroxyapatite of animal bone origin (HABO) was tested in all experiments. The highest citric acid production by free yeast cells of 20.4 g/L and 18.7 g/L was reached after 96 h of fermentation in the absence and presence of 3 g/L HABO, respectively. …”
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Living with Hepatitis C Virus: A Systematic Review and Narrative Synthesis of Qualitative Literature by Laura E. Dowsett, Stephanie Coward, Diane L. Lorenzetti, Gail MacKean, Fiona Clement

“…Studies were included if they focused on adults diagnosed with HCV; reported experience living with HCV; and described original research. Results. 46 studies were included. …”
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Renal Sinus Lipomatosis in Transplanted Kidneys: An Unusual Clinical Case by Luca Apicella, Gianfranco Vallone, Sossio Vitale, Gianluca Garofalo, Luigi Russo, Riccardo Gallo, Stefano Federico, Massimo Sabbatini

“…Renal sinus lipomatosis (RSL) represents an abnormal proliferation of the adipose tissue surrounding the renal pelvis of uncertain origin, associated with aging, obesity, steroid excess, infections, and calculosis. …”
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Revisiting pangenome openness with k-mers by Parmigiani, Luca, Wittler, Roland, Stoye, Jens

“…Pangenomics is the study of related genomes collectively, usually from the same species or closely related taxa. Originally, pangenomes were defined for bacterial species. …”
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Cerebrovascular Accident Secondary to Paradoxical Embolism Following Arteriovenous Graft Thrombectomy by Jolina Pamela Santos, Zaher Hamadeh, Naheed Ansari

“…These findings suggest that the stroke occurred as a result of an embolus originating from the AVG. Paradoxical cerebral embolism is uncommon but can occur after thrombectomy of clotted vascular access in ESRD patients. …”
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Study on the Generalized Displacement Boundary and Its Analytical Prediction for Ground Movements Induced by Shield Tunneling by Qianlong Tang, Fudong Chen, Mingfeng Lei, Binbin Zhu, Limin Peng

“…Then, a universal pattern of displacement boundary condition around the tunnel cavity is originally introduced, which is solved as the combination of three fundamental deformation modes, namely, uniform convergence, vertical translation, and ovalization. …”
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Good living and family farming in the Totonacapan of Puebla, Mexico by Mauricio Torres-Solís, Benito Ramírez-Valverde, José Pedro Juárez-Sánchez, Mario Aliphat Fernández, Gustavo Ramírez Valverde

“…The search for an answer to the contemporary civilizational crisis, makes it necessary to examine recent proposals originated in Native American ideas about Good Living and forms of social responsibility based on an adequate relationship between human societies and nature. …”
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New Steroid–Alkaloid Bioconjugates as Potential Bioactive Compounds: Synthesis, Spectroscopic and In Silico Study by Hanna Koenig, Karolina Babijczuk, Kamil Ostrowski, Damian Nowak, Tomasz Pospieszny, Beata Jasiewicz

“…The focus on compounds of natural origin is gaining prominence, with steroids and alkaloids representing notable examples. …”
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A Pilot Study on Dietary Approaches in Multiethnicity: Two Methods Compared by Romina Valentini, Maria Grazia Dalfrà, Michela Masin, Antonella Barison, Marcon Marialisa, Eva Pegoraro, Annunziata Lapolla

“…We compared maternal and fetal outcomes between two multiethnic groups of pregnant women, one adopting a food plan that included dishes typical of the foreign women's original countries (the “ethnic meal plan” group), while the other group adopted a standard meal plan. …”
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The Preservation of Ratib Saman in Palembang, 2000-2019 by Indah Pratiwi, Sakinah Sakinah, Syarifuddin Syarifuddin, Supriyanto Supriyanto

“…The historical method used to get factual explanations on the origin of Ratib Saman. The data collection was conducted by observation, documentation, and interview. …”
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Determination of inorganic elements in pine pollen by ICP-MS and safety and health risk assessment by Hao LIU, Haitao GUO, Aixi JI, Shuqi LI, Shaojun YU, Guohua YANG, Zhuoer LIU, Yonggang LIU

“…The characteristic spectra and correlation coefficient matrix of inorganic elements in pine pollen were drawn by Origin 2021 and Micro-Signal platform. The safety of pine pollen was evaluated by calculating the single pollution index Pi of heavy metal elements. …”
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Novel Multiple Criteria Group Decision-Making Method Based on Hesitant Fuzzy Clustering Algorithm by Hongya Bian, Deqing Li, Yuang Liu, Rong Ma, Wenyi Zeng, Zeshui Xu

“…The results illustrate that the proposed method can provide more reasonable and credible rankings comparing with existing methods owing to keeping original data during computation.…”
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Diagnostic Features of Common Oral Ulcerative Lesions: An Updated Decision Tree by Hamed Mortazavi, Yaser Safi, Maryam Baharvand, Somayeh Rahmani

“…Thereafter, English-language articles published since 1983 to 2015 in both medical and dental journals including reviews, meta-analyses, original papers, and case reports were appraised. Upon compilation of the relevant data, oral ulcerative lesions were categorized into three major groups: acute, chronic, and recurrent ulcers and into five subgroups: solitary acute, multiple acute, solitary chronic, multiple chronic, and solitary/multiple recurrent, based on the number and duration of lesions. …”
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Improving Robustness of Biometric Identity Determination with Digital Watermarking by Juha Partala, Angelos Fylakis, Anu Pramila, Anja Keskinarkaus, Tapio Seppänen

“…This knowledge could originate, for example, from the tagging of those people on a social network. …”
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