Cyclin-Dependent Kinase-Like 5 (CDKL5): Possible Cellular Signalling Targets and Involvement in CDKL5 Deficiency Disorder by Syouichi Katayama, Noriyuki Sueyoshi, Tetsuya Inazu, Isamu Kameshita

“…Cyclin-dependent kinase-like 5 (CDKL5, also known as STK9) is a serine/threonine protein kinase originally identified in 1998 during a transcriptional mapping project of the human X chromosome. …”
Get full text

Unveiling the inhibitory effect of hydrogen-decorated voids and dislocation loops on the glide of edge dislocation in tungsten by Qing-Yuan Ren, Yu-Hao Li, Yu-Chen Du, Tian-Ren Yang, Dmitry Terentyev, Wei-Zhong Han, Hong-Bo Zhou, Guang-Hong Lu

“…Tungsten (W), as the most promising candidate for plasma-facing materials, will experience significant irradiation hardening in nuclear fusion environment, which is originated from the formation of displacement damages, such as voids and dislocation loops. …”
Get full text

Research on Influence of Different Simulation Methods of Bypass Flow in Thermal Hydraulic Analysis on Temperature Distribution in HTR-10 by Shiyan Sun, Youjie Zhang, Yanhua Zheng

“…In this paper, the thermal hydraulic analysis models of HTR-10 with bypass flow channels simulated at different positions are designed based on the flow distribution scheme of the original core models and combined with the actual position of the core bypass flow. …”
Get full text

The planning process for marketing a service about to enter a foreign market: a concept case study by Blaženko Perić, Tanja Winter, Marcel Piskač, Ajla Rizvan, Neven Mehun, Tina Vukasović

“…By putting emphasis on customer-centricity, agility, and innovation, businesses can improve their competitiveness and establish a strong presence. Originality/Value – this concept case study contributes to the literature by providing a comprehensive marketing plan tailored specifically for the German market, integrating both theoretical frameworks and practical insights. …”
Get full text

Infantile Extracranial Rhabdoid Tumor of the Scalp by Sura Al Rawabdeh, Deifallah Alsharari, Hayat Khasawneh, Ola M. Al Waqfi, Qamar Yaser Malabeh, Hiathem Abu Alhaija, Raed Mohammad Aljubour, Hamzeh M. Alkhawaldeh

“…Extracranial rhabdoid tumor is a rare tumor that can originate in multiple organs, and it is most commonly seen in the kidneys. …”
Get full text

Mesenchymal Stem Cell-Derived Extracellular Vesicles: Roles in Tumor Growth, Progression, and Drug Resistance by Xiaoyan Zhang, Huaijun Tu, Yazhi Yang, Lijun Fang, Qiong Wu, Jian Li

“…MSCs-derived extracellular vesicles (MSC-EVs) could mimic the effects of the mesenchymal stem cells from which they originate. Different studies have reported that MSC-EVs may exert various effects on the growth, metastasis, and drug response of different tumor cells by transferring proteins, messenger RNA, and microRNA to recipient cells. …”
Get full text

A Rare Case of Acute-Onset Spastic Quadriparesis Caused by a Chondroma of the Cervical Spine by Kaori Momota, Toshihiko Nishisho, Ryo Miyagi, Shunichi Toki, Kazuta Yamashita, Fumitake Tezuka, Yoichiro Takata, Toshinori Sakai, Akihiro Nagamachi, Toru Maeda, Koichi Sairyo

“…Moreover, chondromas of the extraskeletal origin are also very rare. In this case report, we describe an extremely rare case of chondroma arising from the ligamentum flavum in the cervical spine. …”
Get full text

Natural repeated backcrosses lead to triploidy and tetraploidy in parthenogenetic butterfly lizards (Leiolepis: Agamidae) by Eduard Galoyan, Roman Nazarov, Marie Altmanová, Sergey Matveevsky, Ivan Kropachev, Dmitrij Dedukh, Eugene Iryshkov, Mark Pankin, Natalia Sopilko, Oleg Nikolaev, Nikolai Orlov, Marine Arakelyan, Jiří Klíma, Evgeniya Solovyeva, Tao Nguyen, Lukáš Kratochvíl

“…Within the range of L. guentherpetersi, we found an adult tetraploid male with three L. guttata and one L. reevesii haploid genomes. It probably originated from fertilisation of an unreduced triploid L. guentherpetersi egg by a L. guttata sperm. …”
Get full text

Case studies on domestic refrigerator energy rationing by implementing a hybrid PV-driven condenser cooling system by Moataz M. Abdel-Raouf, M.A. Eid, M. Elsayed, M. Salah Mansour

“…The results of the modified condenser cooling systems, powered by either an electrical grid or a limited (PV) system, were compared to those of the original refrigerator. The experiments show that the blast cooling and freezing efficiency of chilled and frozen products increased by 32 %, 39.4 %, 39.3 %, and 36 %, respectively, when the refrigerator was partially and fully loaded. …”
Get full text

Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in Rafflesiaceae by Wicaksono Adhityo, Meitha Karlia, Wan Kiew-Lian, Mat Isa Mohd Noor, Parikesit Arli Aditya, Molina Jeanmaire

“…This study provides evidence that certain miRNAs with ancient origins in land plants still exist in Rafflesiaceae, though some may have been coopted by parasites to target host genes.…”
Get full text

Artificial weathering aging of PPT coatings made from recycled PET to protect concrete: Nanomechanical properties evaluation by Adrián Bórquez-Mendivil, Jorge Luis Almaral-Sánchez, Jesus Eduardo Leal-Perez, César Modesto-Acosta, Joaquin Flores-Valenzuela, Orlando Auciello, Blanca Alicia García-Grajeda, José Miguel Mendivil-Escalante, Sergio G. Flores-Gallardo, Roberto P. Talamantes-Soto, Abel Hurtado-Macías

“…The morphology and microstructure were analyzed by scanning electron microscopy (SEM) and atomic force microscopy (AFM); with these techniques, it was possible to identify the deterioration of the coating (porosity and origin of cracks) and the increase in roughness (6 ± 1 nm to 746 ± 5 nm), respectively. …”
Get full text

Eye Motility Alterations in Retinitis Pigmentosa by Raffaele Migliorini, Anna Maria Comberiati, Giovanni Galeoto, Manuela Fratipietro, Loredana Arrico

“…Therefore, the disorders of OM lead to a genetic origin.…”
Get full text

Effect of Freeze-Thaw Cycles on the Mechanical Properties of Polyacrylamide- and Lignocellulose-Stabilized Clay in Tibet by Haiping Shi, Zhongyao Li, Wenwei Li, Shaopeng Wang, Baotian Wang, Peiqing Wang

“…Samples stabilized by PAM and lignocellulose have higher internal friction angles, cohesion, and unconfined compressive strength and can retain about 80% of the original strength after 10 freeze-thaw cycles. PAM fills the pores between soil particles and provides adhesion. …”
Get full text

Informative architectures and citizen participation: a comparative study between the digital platforms Decidim and Rousseauv by Eli Borges Junior, Bruno Madureira Ferreira

“…This article looks at this question using a comparative study between two digital informative architectures: the Five Star Movement’s (originally in Italian “Movimento 5 Stelle”) Rousseau platform in Italy, and the Decidim platform, developed after the 15M movement in Spain by a collaboration of entities from different countries. …”
Get full text

Molecular genetic methods for intestinal microbiome investigation by O. L. Kardymon, A. V. Kudryavtseva

“…Intestinal microbiome disorders play the leading role in development of many diseases of infectious and noninfectious origin. Monitoring of specific type, quantitative ratio of different types and strains of microorganisms in healthy people and at various diseases is essential for to develop strategy for microbiome restitution by microbial therapy. …”
Get full text

Smart Agricultural Pest Detection Using I-YOLOv10-SC: An Improved Object Detection Framework by Wenxia Yuan, Lingfang Lan, Jiayi Xu, Tingting Sun, Xinghua Wang, Qiaomei Wang, Jingnan Hu, Baijuan Wang

“…The experimental results show that compared with the original YOLOv10, the model generated by the improved algorithm improves the accuracy by 5.88 percentage points, the recall rate by 6.67 percentage points, the balance score by 6.27 percentage points, the mAP value by 4.26 percentage points, the bounding box loss by 18.75%, the classification loss by 27.27%, and the feature point loss by 8%. …”
Get full text

Detection and isolation of a new member of Burkholderiaceae-related endofungal bacteria from Saksenaea boninensis sp. nov., a new thermotolerant fungus in Mucorales by Yusuke Takashima, Kohei Yamamoto, Yousuke Degawa, Yong Guo, Tomoyasu Nishizawa, Hiroyuki Ohta, Kazuhiko Narisawa

“…The discovery of a culturable BRE lineage in the genus Saksenaea will add new insight into the evolutional origin of mucoralean fungus-BRE associations and emphasize the need to pay more attention to endofungal bacteria potentially associated with isolates of thermotolerant mucoralean fungi causing mucormycosis.…”
Get full text

Non-target feature filtering for weakly supervised semantic segmentation by Xuesheng Zhou, Yan Li, Guitao Cao, Wenming Cao

“…CDCC effectively addresses the issue of unsuitability in the clustering group relationships of the original features under specified class conditions. …”
Get full text

Psychometric analysis of a simplified version of the Emotion Regulation Questionnaire in Mexican adults: The ERQ-CA-9 by Pablo D. Valencia, Anabel De la Rosa-Gómez

“…Background: The Emotion Regulation Questionnaire (ERQ) is the most widely used measure of cognitive reappraisal and expressive suppression, two core emotion regulation strategies. However, the original ERQ has complex wording, which may make it difficult for readers of lower educational levels. …”
Get full text

Pituitary Adenylate Cyclase-Activating Polypeptide Protects Glomerular Podocytes from Inflammatory Injuries by Kenichi Sakamoto, Kyoko Kuno, Minoru Takemoto, Peng He, Takahiro Ishikawa, Shunichiro Onishi, Ryoichi Ishibashi, Emiko Okabe, Mayumi Shoji, Akiko Hattori, Masaya Yamaga, Kazuki Kobayashi, Harukiyo Kawamura, Hirotake Tokuyama, Yoshiro Maezawa, Koutaro Yokote

“…Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide, which was originally isolated from the ovine hypothalamus and reportedly has diverse biological functions. …”
Get full text