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6321
The Effects of TLR Activation on T-Cell Development and Differentiation
Published 2012-01-01“…T cells consist of various subsets, that is, Th1, Th2, Th17, T follicular helper (Tfh), cytotoxic T lymphocytes (CTLs), regulatory T cells (Treg) and these originate from thymic progenitor thymocytes. T-cell receptor (TCR) activation in distinct T-cell subsets with different TLRs results in differing outcomes, for example, activation of TLR4 expressed in T cells promotes suppressive function of regulatory T cells (Treg), while activation of TLR6 expressed in T cells abrogates Treg function. …”
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6322
Synthesis of Phase-Only Reconfigurable Linear Arrays Using Multiobjective Invasive Weed Optimization Based on Decomposition
Published 2014-01-01“…First, novel strategies are introduced in invasive weed optimization (IWO) to make original IWO fit for solving multiobjective optimization problems; then, the modified IWO is integrated into the framework of the recently well proved competitive multiobjective optimization algorithm MOEA/D to form a new competitive MOEA/D-IWO algorithm. …”
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6323
Polycystic ovary syndrome (PCOS): progress towards a better understanding and treatment of the syndrome
Published 2024-04-01“…However, the underlying mechanisms of its transmission remain unknown, thus limiting the development of effective therapeutic strategies.This article highlights how an altered fetal environment (prenatal exposure to high levels of anti-Müllerian hormone) can contribute to the onset of PCOS in adulthood and lead to the transgenerational transmission of neuroendocrine and metabolic traits through alterations in the DNA methylation process.The originality of the translational findings summarized here involves the identification of potential biomarkers for early diagnosis of the syndrome, in addition to the validation of a promising therapeutic avenue in a preclinical model of PCOS, which can improve the management of patients suffering from the syndrome.…”
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6324
Aging Adults and Seasonal Influenza: Does the Vitamin D Status (H)Arm the Body?
Published 2012-01-01“…Vitamin D (VitD), although originally described as an essential hormone for bone and mineral homeostasis, appears to have an active role in regulating specific facets of human immunity. …”
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6325
Role of polymers in encapsulation and shape-stabilization of phase change materials (PCMs) for thermal energy storage applications: an overview
Published 2024-05-01“…To improve the performance efficiency and proper handling of PCMs, they are often encapsulated or confined within a shape-stabilized supporting material of an inorganic or organic origin. This review emphasizes the current research status of the polymer-based PCMs developed using the various PCMs–polymer combinations available, material characteristics, encapsulation, and shape-stabilization methods and provides detailed information on the contribution of polymers toward the enhancement of PCM end-product properties, in an avant-garde technology related to TES.…”
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6326
Hedgehog pathway inhibitors (HHI) combined with radiotherapy and immunotherapy for advanced basal cell carcinoma: a case report
Published 2025-12-01“…However, there is a scarcity of evidence-based guidelines for the management of patients with advanced or metastatic BCC, particularly those who develop resistance to HHI therapy.Materials and methods We report the case of a patient with advanced BCC of the head and neck, which originated from a nevus sebaceous.Results The patient initially responded well to sonidegib, an HHI, but resistance emerged within a month. …”
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6327
Does Large‐Scale Crustal Flow Shape the Eastern Margin of the Tibetan Plateau? Insights From Episodic Magmatism of Gongga‐Zheduo Granitic Massif
Published 2022-06-01“…Modeling results suggest that Cenozoic magmas originated at depths of ∼30–40 km, the depth that crustal flow has been postulated to occur at. …”
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6328
A Survey of Blockchain Applications for Management in Agriculture and Livestock Internet of Things
Published 2025-01-01“…However, this sector faces significant challenges, including ambiguity in product origins and limited regulatory oversight of IoT devices. …”
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6329
UAV Detection with Passive Radar: Algorithms, Applications, and Challenges
Published 2025-01-01“…We begin by exploring the origins of passive radar and then provide a comprehensive overview of its progress from multiple angles, particularly focusing on its application in UAV detection. …”
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6330
Effective Inertial Hand Gesture Recognition Using Particle Filtering Based Trajectory Matching
Published 2018-01-01“…The improvement is based on the resampling method making the original filter much faster to converge. After smoothing, the trajectory is then converted to low-definition images which are further sent to a backpropagation neural network (BP-NN) based recognizer for matching. …”
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6331
A review on the magnetotelluric studies over the Central Asian Orogenic Belt—recent developments and future aspects
Published 2025-01-01“…The Central Asian Orogenic Belt (CAOB) was originated from the subduction, closure, convergence, and post-collisional extension of the Paleo-Asian Ocean located between the North China Craton, Tarim Craton, and the Siberian Craton during the late Permian to early Triassic. …”
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6332
The Effects of Temperature and Impact Velocity on the Shock Wave Response of Pore-Embedded Metallic Glasses
Published 2022-01-01“…Moreover, the spall event originated from the formation and coalescence of tension transformation zones, leading to the formation of nanovoids in the system. …”
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6333
Tectonic relationships between the Paleozoic basement and the Mesozoic cover succession in the northern Dora-Maira Massif (Susa Valley, Western Alps)
Published 2025-12-01“…Prior to the Alpine polyphase deformation, the basement-cover interface likely originated as a weak horizon within the Early Triassic, localizing deformation and forming the primary detachment zone.…”
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6334
Natural variation in growth and yield to waterlogging across climate-diverse pennycress accessions
Published 2025-12-01“…We used climate modeling data to assess spring soil moisture levels in the geographic origins of 471 natural pennycress accessions. We selected 34 accessions with variation in predicted soil moisture and tested survivability under prolonged waterlogging at the rosette stage. …”
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6335
Study on the Occurrence of Double Bottom Simulating Reflectors in the Makran Accretionary Zone
Published 2025-01-01“…Based on the multi-channel seismic reflection data acquired over the Makran accretionary wedge, this work studies the origin of the double BSR in the Makran accretionary wedge and its association with fluid escape events. …”
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6336
Breastfeeding impact on kidney health : updated evidence
Published 2024-12-01“…This review reaffirms the critical importance of breastfeeding for both immediate infant health, and its potential to shape renal health throughout life, thereby, supporting the Developmental Origins of Health and Disease (DOHaD) hypothesis, and emphasizing the necessity for ongoing advocacy in this domain.…”
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6337
Identifying and Prioritizing Critical Success Factors in Telecommunication Supply Chain Management in Mazandaran Province using DANP
Published 2021-05-01“…According to the experts' answers and the analysis results, repair and maintenance are the essential components in prioritizing the critical success factors in managing the telecommunication supply chain of Mazandaran province. Originality/Value: The study showed that companies could gain a tremendous competitive advantage by identifying and prioritizing the critical factors of success in supply chain management, shedding light on better policymaking in the field.…”
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6338
Analysis of the Potential for a Hillside Collapse for a Community in Changhua County, Taiwan
Published 2019-01-01“…Changhua County contains 589 villages, 81 of which are prone to hillsides (including protected forest). In addition to original potential debris flow torrent communities, disaster-resistant communities have been established under the guidance of Soil and Water Conservation Bureau (SWCB), Council of Agriculture in Taiwan; Changhua County Government also plans to establish disaster-resistant communities in other hillside communities. …”
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6339
Technical Considerations of Giant Right Coronary Artery Aneurysm Exclusion
Published 2016-01-01“…Following right atriotomy, the fistula was oversewn and the aneurysmal right coronary artery ligated at its origin and at several points along its course. A saphenous vein graft was anastomosed to the posterior descending artery. …”
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6340
Epipolar Plane Image Rectification and Flat Surface Detection in Light Field
Published 2017-01-01“…In this paper we propose detecting printed photos from original scenes, which fully exploit angular information of light field and characteristics of the flat surface. …”
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