Physiochemical and functional evaluation of the first-in-class anti-cancer IgE antibody drug, MOv18, through process development and good manufacturing practice production by Heather J Bax, Jitesh Chauhan, Alexandra J McCraw, Melanie Grandits, Chara Stavraka, Heike Lentfer, Tim Hillyer, Simon Carroll, Kim Vigor, Chris Selkirk, Mariangela Figini, Jack Cheeseman, Paulina A Urbanowicz, Richard A Gardner, Daniel I R Spencer, Nigel Westwood, Sarah Mellor, James Spicer, Debra H Josephs, Sophia N Karagiannis

“…We confirm the suitability of the pipeline described for generating intact, functionally active, clinical-grade material for this novel therapeutic class as an Investigational Medicinal Product (IMP), with comparable characteristics to the original research-grade antibody. Furthermore, we screened patient blood ex vivo for potential type I hypersensitivity reaction to MOv18 IgE, using the basophil activation test, to identify patients not predicted to be hypersensitive to MOv18 IgE administration. …”
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Bibliometric analysis of laryngeal cancer treatment literature (2003–2023) by Yan Zhao, Jiancheng Xue

“…To ensure data quality, conference papers, letters, and editorial materials were excluded, focusing only on original research papers and review articles. Results: The analysis showed that 760 theoretical works and review papers were published in 96 academic journals by 4210 authors from 1148 institutions across 60 countries/regions. …”
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Rapid molecular assays versus blood culture for bloodstream infections: a systematic review and meta-analysisResearch in context by Gabriella Anna Rapszky, Uyen Nguyen Do To, Veronika Eszter Kiss, Tamás Kói, Anna Walter, Dorottya Gergő, Fanni Adél Meznerics, Márton Rakovics, Szilárd Váncsa, Lajos Vince Kemény, Dezső Csupor, Péter Hegyi, Michael R. Filbin, Csaba Varga, Bánk G. Fenyves

“…Eligible studies included patients with suspected or documented BSI, tested with both an RMA (turnaround time of ≤12 h, targeting ≥20 pathogens) and BC. Non-original research articles and animal studies were excluded. …”
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Practice Guidelines for the Value Evaluation of Clinical Pharmacy Services (version 2) by Liuyun Wu, Ziyan Lv, Min Chen, Xingyue Zheng, Lian Li, Shan Du, Lizhu Han, Qinan Yin, Yin Wang, Xinxia Liu, Wenyuan Li, Xuefei Huang, Hulin Wang, Xiaoqing Yi, Xiaojiao Cui, Zhujun Chen, Yueyuan Wang, Yingying Hou, Xi Zheng, Yang Lei, Mengqiu Gou, Yue Wu, Fengjiao Kang, Fengqun Cai, Shuhong Liang, Yong Yang, Jinqi Li, Yuan Bian

“…The content of these included indicators was searched according to the PICO principle, followed by systematic reviews, meta-analyses, network meta-analyses, and related original research. Each search strategy was reviewed and approved by the guidelines steering committee. …”
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Immunotherapy and Antivascular Targeted Therapy in Patients’ Treatment with Concurrent Malignant Tumors after Organ Transplantation: Opportunity or Challenge by Bairu Shen, Zi Guo, Peng Huang, Minghua Tan, Xiaoshen Zhang, Siyao Lin, Changshan Song, Jiaqing Wang, Minqian Huang

“…Data from only 40 papers met our requirements, which included 2 literature reviews, 4 original researches, and 34 case reports from 2016 to 2020. …”
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How Significant Are Marine Invertebrate Collagens? Exploring Trends in Research and Innovation by Mariana Almeida, Tiago Silva, Runar Gjerp Solstad, Ana I. Lillebø, Ricardo Calado, Helena Vieira

“…The findings reveal that research dates back to the 1970s, and after a period of reduced activity, interest in collagens from several marine invertebrate groups was renewed around 2008, likely driven by the increased commercial interest in these biomolecules of marine origin. Research and development are predominantly reported from China and Japan, highlighting significant research interest in cnidarians (jellyfish), echinoderms (sea cucumbers, sea urchins and starfish), molluscs (squid and cuttlefish) and sponges. …”
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Young Muslim generations and sadaqah through digital platforms: Do sadaqah literacy and religiosity matter? by Ahmad Santoso, Heri Sudarsono, Weni Hawariyuni

“…In addition, the BSI Maslahat needs to increase the religiosity of the young Muslim generation by collaborating with related institutions. Originality – Research on the intention of the younger generation of Muslims to pay sadaqah digitally has not been carried out much by previous research. …”
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