HIV-Envelope–Dependent Cell-Cell Fusion: Quantitative Studies by Leonor Huerta, Nayali López-Balderas, Evelyn Rivera-Toledo, Guadalupe Sandoval, Guillermo Gómez-Icazbalceta, Carlos Villarreal, Edmundo Lamoyi, Carlos Larralde

“…Even in the asymptomatic stage of infection, multinucleated cells have been observed in different organs, indicating that fused cells may be generated and remain viable in the tissues of patients. …”
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Analysis of the relationship between environmental particulate matter exposure and congenital diseases, as well as the epidemiological trends and burden of impact on newborns by Mulati Julaiti, Dilixiati Wubuli, Tingting Cui, Nadire Nijiati, Pengfei Huang, Bowen Hu

“…Two-sample Mendelian randomization methods were applied, and the Global Burden of Disease (GBD) database was leveraged to analyze the trends and burden of neonatal diseases from 1990 to 2021 and to forecast the burden for 2022–2052.Results: Significant causal associations were identified between PM2.5, PM10 and specific congenital malformations, including gallbladder, bile duct, liver anomalies, and malformations of the reproductive organs and broad ligaments. A review of GBD data indicates a decline in the prevalence of neonatal DALYs and YLDs attributed to ambient particulate matter over the past three decades. …”
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Case report: an unusual long-term evolution of a diffuse midline glioma, H3K27 altered by Michael Griessmair, Michael Griessmair, Claire Delbridge, Claus Zimmer, Eva Mayr, Arthur Wagner, Julian Canisius, Marie-Christin Metz, Benedikt Wiestler, Benedikt Wiestler

“…Molecular neuropathology revealed the diagnosis of diffuse midline glioma with a H3K27M mutation WHO (World Health Organization) CNS (central nervous system) grade 4. Interestingly, MR imaging conducted for migraine diagnosis 6 years ago in retrospect already showed a small, nodular T2w hyperintense lesion in the right thalamus.ConclusionDespite a more precise, molecularly driven classification of pediatric HGG (high-grade glioma) in the 5th edition of the WHO classification of CNS tumors, many genetic factors influencing the biological tumor development as well as the precise molecular evolution of tumors remain unclear. …”
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Evaluation of 3D-CRT Radiotherapy Treatment Planning with Radiobiological Effects in Patient-Specific 3D Printed Anthropomorphic Phantom Postmastectomy Breast Cancer Axillary Metas... by Endarko Endarko, Aditya Hariyanto, Siti Aisyah, Nandia Kavilani, Ahmad Syafi'i

“…From the variations, the radiation dose received by planning target volume (PTV) chest wall, PTV-Axillary, and organs at risk (OARs) was evaluated to determine the best planning technique through dosimetry verification. …”
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Batterer typologies: substance use, impulsivity and results of an IPVAW offender treatment program in Spain by Pedro V. Mateo-Fernández, Pedro V. Mateo-Fernández, Pedro V. Mateo-Fernández, Iria Osa-Subtil, Iria Osa-Subtil, Iria Osa-Subtil, Román Ronzón-Tirado, María Elena de la Peña Fernández

“…Combined with drunkenness, it can materially increase the likelihood of intimate partner violence.MethodsThe present study examines substance use and impulsivity among a sample of 243 men convicted of IPVAW offences under the Spanish Gender Violence Act (Organic Law 1/2004) in relation to the levels of violence and psychopathologies presented by these perpetrators, in order to understand the results of court-ordered psychological treatments provided under Spain’s Gender Violence Offenders Intervention Program. …”
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Does preeclampsia impact the gut microbiota of preterm offspring during early infancy? by Yang Chen, Zhou-Ting Yi, Hai-Long Yu, Xiao-Yan Wu, Jun-Ping Wang, Chuan Nie, Hui Li, Sheng-Hui Li, Qiu-Long Yan, Tian-Wen He, Min-Chai Chen, Xin-Yue Yang, Ji-Ying Wen, Li-Juan Lv

“…Abstract Preeclampsia (PE) is a pregnancy complication characterized by high blood pressure and organ damage. This study investigates the differences in the gut microbiota between preterm neonates born to mothers with PE and those born to mothers without PE (PR), aiming to understand how maternal health conditions like PE influence neonatal gut microbiota. …”
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Metagenomic analysis of gut microbiota diversity in poultry before and after antibiotic administration by O. V. Prasolova, N. I. Malik, I. A. Timofeeva, N. A. Kirsanova, E. V. Krylova, E. V. Malik, I. A. Rusanov, N. A. Chupakhina

“…The revealed increase in the proportion of Lactobacillaceae during antibiotic treatment suggests the ability of a healthy organism to restore the microbiota balance. The results of metagenomic data bioinformatics (without truncation) showed the presence of 158 microorganism species in the chick microbiota, 38% of which were classified as nonculturable.…”
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Post-craniotomy infections: A point-by-point approach by Giovanni Carone, Marta Bonada, Evelyn Gisell Belotti, Eugenia D'Angeli, Annica Piccardi, Fabio Martino Doniselli, Guido Gubertini, Cecilia Casali, Francesco DiMeco, Massimiliano Del Bene

“…Surgical intervention is often indispensable for managing organ-space infections, with a trend towards bone flap preservation and one-step cranioplasty procedures in certain cases. …”
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Visual Mapping of Operating Theater Team Dynamics and Communication for Reflexive Feedback and Surgical Practice Optimization by Surya Surendran, MA, Candice Bonaconsa, MSc, Vrinda Nampoothiri, PharmD, Oluchi Mbamalu, PhD, Anu George, PGDip, Swetha Mallick, MCh, Sudheer OV, MCh, Alison Holmes, MD, Marc Mendelson, PhD, Sanjeev Singh, PhD, Gabriel Birgand, PhD, Esmita Charani, PhD

“…Implementing the World Health Organization surgical safety checklist was inconsistent across pathways and does not match reported compliance data. …”
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Comparative Efficacy and Safety of Targeted Therapies for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Network Meta-Analysis by Yusi Chen, Fang Li, Jun Luo, Jingyuan Chen, Peng Luo, Jiang Li

“…Sildenafil was identified as the best drug in terms of improving the New York Heart Association/World Health Organization functional class with a probability of 87.3%. …”
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Vehicle Turn Pattern Counting and Short Term Forecasting Using Deep Learning for Urban Traffic Management System by Sundarakrishnan Narayanan, Sohan Varier, Tarun Bhupathi, Manaswini Simhadri Kavali, Mohana, P. Ramakanth Kumar, K. Sreelakshmi

“…Hence, as part of the Bengaluru Mobility Challenge 2024, organized by Bengaluru Traffic Police in collaboration with The Indian Institute of Science, we propose a solution to address the issue by developing a predictive model to estimate vehicle counts by turning pattern from traffic video footage. …”
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Long Term School Based Deworming against Soil-Transmitted Helminths Also Benefits the Untreated Adult Population: Results from a Community-Wide Cross Sectional Survey by Paul M. Gichuki, Gabriel Mbugua, Edwin K. Kiplelgo, Tabitha W. Irungu, Charles Mwandawiro

“…The primary control strategy for these infections is preventive chemotherapy (PC) delivered through school based deworming (SBD) programs. The World Health Organization (WHO) recommends the inclusion of other at-risk groups in the PC. …”
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Evaluation of ChatGPT-4 for the detection of surgical site infections from electronic health records after colorectal surgery: A pilot diagnostic accuracy study by Josep M. Badia, Daniel Casanova-Portoles, Estela Membrilla, Carles Rubiés, Miquel Pujol, Joan Sancho

“…Patient records were reviewed by both manual surveillance and ChatGPT, which was tasked with identifying SSI and categorizing them as superficial, deep, or organ-space infections. Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) were calculated. …”
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Kidney transplant utilising donors after circulatory death: The first report from the African continent by T du Toit, K Manning, L Bertels, G Hoffman, D Thomson, Z A Barday

“…At Groote Schuur Hospital in Cape Town, South Africa, the number of deceased organ donors has declined over the past 2 decades, necessitating a more liberal approach to donor selection. …”
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Synergistic Antibacterial Action of Norfloxacin-Encapsulated G4 Hydrogels: The Role of Boronic Acid and Cyclodextrin by Monica-Cornelia Sardaru, Irina Rosca, Simona Morariu, Elena-Laura Ursu, Alexandru Rotaru

“…Comprehensive characterization using FTIR, circular dichroism, X-ray diffraction, SEM, AFM, and rheological measurements confirmed successful synthesis and revealed that higher boronic acid content correlated with a stronger, more organized network. The most effective hydrogel displayed an inhibition zone of 25 mm in disk diffusion assays, and was further explored as a drug delivery platform, with the aim to exploit the capacity of the free <i>β</i>-CD cavity of the hydrogels to incorporate hydrophobic drugs. …”
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Identification of novel clinical subtypes in patients with microscopic polyangiitis using cluster analysis: multicenter REVEAL cohort study by Ayana Okazaki, Shogo Matsuda, Takuya Kotani, Keisuke Fukui, Keisuke Fukui, Takaho Gon, Ryu Watanabe, Atsushi Manabe, Mikihito Shoji, Keiichiro Kadoba, Ryosuke Hiwa, Wataru Yamamoto, Motomu Hashimoto, Tohru Takeuchi

“…Cluster 3 included patients in the younger-onset limited-organ disease group (N=45). Cluster 4 was comprised of an ILD-predominant group without kidney involvement (N=36). 61 patients died during follow-up, with 32 dying of respiratory-related causes. …”
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Optimizing the dose-averaged linear energy transfer for the dominant intraprostatic lesions in high-risk localized prostate cancer patients by Bo Zhao, Nobuyuki Kanematsu, Shuri Aoki, Shinichiro Mori, Hideyuki Mizuno, Takamitsu Masuda, Hideyuki Takei, Hitoshi Ishikawa

“…This study investigated the feasibility of focal dose-averaged linear energy transfer (LETd) boost for prostate carbon-ion radiotherapy to deposit higher LETd to DILs while ensuring desired relative biological effectiveness weighted dose coverage to targets and sparing organs at risk (OARs). Materials and methods: A retrospective planning study was conducted on 15 localized prostate cancer cases. …”
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Exploring the epidemiology of disseminated intravascular coagulation: protocol for the DANish Disseminated Intravascular Coagulation (DANDIC) Cohort Study by Henrik Toft Sørensen, Kasper Adelborg, Jecko Thachil, Anne-Mette Hvas, Simon Flæng, Søren Nygaard, Asger Granfeldt

“…The dataset will be enriched with detailed clinical data from electronic medical charts on aetiologies, bleeding, microthrombus formation, organ failure, thrombosis, treatments and comorbidities. …”
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Gastrointestinal Tract Duplications in Children: A Tertiary Referral Center Experience by Meltem CAGLAR OSKAYLI, Furkan ERSOY, Neslihan GULCIN, Ahmet PIRIM, Seyhmus Kerem OZEL, Seyma OZKANLI, Cigdem ULUKAYA DURAKBASA

“…The total surgical excision with (n=8) or without (n=10) associated organ resection was possible in 18 patients. Partial cyst excision with a complete mucosal removal was done in 1 patient. …”
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hucMSC-Ex Alleviates IBD-Associated Intestinal Fibrosis by Inhibiting ERK Phosphorylation in Intestinal Fibroblasts by Yifei Wang, Yaqin Zhang, Bing Lu, Jianbo Xi, Dickson Kofi Wiredu Ocansey, Fei Mao, Donglin Hao, Yongmin Yan

“…Mesenchymal stem cell-derived exosomes have been proven to exert inhibitory and reversal effects in IBD and other organ fibrosis. In this study, we explored the role of human umbilical cord mesenchymal stem cell-derived exosomes (hucMSC-Ex) in IBD-related fibrosis and its associated mechanism to provide new ideas for the prevention and treatment of IBD-related intestinal fibrosis. …”
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