Drug discovery: a multifactorial ecosystem by Fernando Albericio

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Preferential flow in soils is key to the development of nebkhas in water limited regions by Weicheng Luo, Wenzhi Zhao, Ning An, Chengpeng Sun, Hong Zhou

“…Our results showed that soil properties such as clay and silt content, organic carbon content, total porosity, and soil crust thickness increased with nebkha development stages (BD < SN < LN), indicating that soils in LN had better soil structure and physicochemical properties than those in BD. …”
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Evaluation of the Nutrition Heart Program Through the Four Elements of Community Empowerment Approach by Rika Satyadewi, Galuh Mega Kurnia, Arina Mufida Ersanti, Corie Indria Prasasti

“…There are no local organizations engaged in program implementation. Conclusions: Three of the four elements of community empowerment are evident in the nutrition heart program. …”
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Phytochemical study and evaluation of the antidiabetic and antihyperglycemic activities of the fruit extracts of Physalis peruviana L. (Solanaceae) by Damien S.T. Tshibangu, Fortune S. Kavugho, Carlos N. Kabengele, Adrien T. Masunda, Gédéon N. Bongo, Giresse N. Kasiama, Domaine T. Mwanangombo, Clément L. Inkoto, Clément M. Mbadiko, Benjamin Z. Gbolo, Désiré M. Musuyu, Dorothée D. Tshilanda, Jean Paul K.N. Ngbolua, Pius T. Mpiana

“…Mineralogical analysis showed that the species contains minerals, essential for the organism and for the survival of the plant at significant concentrations (K, P, Ca, Mg, Na, Zn, etc.). …”
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Spatial-temporal Characteristics and Source Apportionment of Ambient VOCs in Southeast Mountain Area of China by Xiaoting Ji, Ke Xu, Dan Liao, Gaojie Chen, Taotao Liu, Youwei Hong, Sijun Dong, Sung-Deuk Choi, Jinsheng Chen

“…Abstract Seasonal variations and sources of ambient volatile organic compounds (VOCs) were conducted at the county and rural sites in a mountain area of southeastern China. …”
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Effects of the Changes of Load and Flue Gas Temperature on the Emission of Particulate Matter from the Coal-fired Unit by Yujia Wu, Zhenyao Xu, Siqi Liu, Minghui Tang, Shengyong Lu

“…The emission concentration of FPM, organic and inorganic components of CPM were obtained. …”
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Effects of Volatile Components on Mixing State and Size Distribution of Individual Black Carbon Aerosols by Kangning Li, XiaoFei Wang, Xiaohui Lu, Hong Chen, Xin Yang

“…However, several low-volatile non-BC substances remained, namely organic species, potassium chloride, potassium nitrate, and other nonvolatile substances. …”
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Evaluation of cellular and physiological alterations of cells from Mytilus galloprovincialis exposed to benzisothiazolinone by Federica Impellitteri, Kristian Riolo, Giorgia Zicarelli, Miriam Porretti, Cristiana Roberta Multisanti, Giuseppe Piccione, Alessia Giannetto, Caterina Faggio

“…This extensive use is reflected in a vast amount of this compound in the environment, which may cause toxic effects in organisms that come in contact with it. In light of the aforementioned context, this work aims to investigate the potential cellular and physiological impact on aquatic organisms through in vitro tests, utilising haemocytes and digestive gland (DG) cells derived from the Mediterranean mussel (Mytilus galloprovincialis). …”
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Digital twins as global learning health and disease models for preventive and personalized medicine by Xinxiu Li, Joseph Loscalzo, A. K. M. Firoj Mahmud, Dina Mansour Aly, Andrey Rzhetsky, Marinka Zitnik, Mikael Benson

“…Early clinical applications of DTs have shown potential in areas like artificial organs, cancer, cardiology, and hospital workflow optimization. …”
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Differentiation of sensory descriptors through co-inoculation of yeast and lactic acid bacteria in wet fermented coffee by Sandy Rodrigues Dias, Nádia Nara Batista, Ana Paula Pereira Bressani, Disney Ribeiro Dias, Rosane Freitas Schwan

“…The bioactive compounds, carbohydrates, and organic acids by HPLC, volatile compounds by GC‒MS, and sensory characteristics were measured by the cupping test. …”
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Mesenchymal stem cells-derived exosomes attenuate mouse non-heart-beating liver transplantation through Mir-17-5p-regulated Kupffer cell pyroptosis by Yang Tian, Ming Jin, Nanwei Ye, Zhenzhen Gao, Yuancong Jiang, Sheng Yan

“…However, the underlying mechanisms of how they can protect organ donation after cardiac death (DCD) livers remain unclear. …”
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Quantifying primary oxidation products in the OH-initiated reaction of benzyl alcohol by R. S. Buenconsejo, S. M. Charan, J. H. Seinfeld, J. H. Seinfeld, P. O. Wennberg, P. O. Wennberg

“…Consistent with the known high SOA yields of catechol, we find that HBA has a very high secondary organic aerosol (SOA) yield. Thus, benzyl alcohol and its oxidation products efficiently produce secondary organic aerosol – under some conditions approaching unity. …”
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Metabolomics and transcriptomics analyses revealed overexpression of TaMGD enhances wheat plant heat stress resistance through multiple responses by Dongyun Ma, Haizhou Hu, Jianchao Feng, Beiming Xu, Chenyang Du, Yang Yang, Yingxin Xie, Chenyang Wang

“…Overall, 146 differentially expressed metabolites (DEMs) were identified in MG1516 and wild-type (WT) under heat stress, with MG1516 exhibiting a higher number of upregulated metabolites, particularly glycolipids, organic acids, and organic oxygen compounds. Furthermore, lipid content and unsaturation analysis revealed that the overexpressing wheat line had a higher lipid content and greater saturation than WT under heat stress. …”
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Clinical Practice Guidelines of the Russian Society for the Study of the Liver, the Russian Gastroenterological Association, the National Scientific Society of Infectious Disease S... by V. T. Ivashkin, V. P. Chulanov, N. A. Mamonova, M. V. Maevskaya, M. S. Zharkova, I. N. Tikhonov, P. O. Bogomolov, E. V. Volchkova, A. S. Dmitriev, O. O. Znojko, E. A. Klimova, K. V. Kozlov, I. E. Kravchenko, E. Yu. Malinnikova, R. V. Maslennikov, M. I. Mikhailov, K. E. Novak, I. G. Nikitin, V. E. Syutkin, E. V. Esaulenko, A. A. Sheptulin, E. N. Shirokova, N. D. Yushchuk

“…In most cases, eradication of viral HCV infection is a real task even in patients at the stage of cirrhosis of the liver, with impaired renal function, HIV co-infection, after solid organs transplantation.…”
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A soft tick vector of Babesia sp. YLG in Yellow-legged gull (Larus michahellis) nests by Bonsergent, Claire, Vittecoq, Marion, Leray, Carole, Jouglin, Maggy, Buysse, Marie, McCoy, Karen D., Malandrin, Laurence

“…YLG DNA was detected in the salivary glands of nymphs, females and males, a necessary organ to infect for transmission to a new vertebrate host. …”
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Laboratory Rotational Spectroscopy Leads to the First Interstellar Detection of Singly Deuterated Methyl Mercaptan (CH2DSH) by Hayley A. Bunn, Silvia Spezzano, Laurent H. Coudert, Jean-Claude Guillemin, Yuxin Lin, Christian P. Endres, Brant Billinghurst, Olivier Pirali, Jes Jørgensen, Valerio Lattanzi, Paola Caselli

“…This is the first interstellar detection of a deuterated sulfur-bearing complex organic molecule and therefore an important step toward understanding the chemical origin of sulfur-based prebiotics.…”
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GC-MS analysis, antimicrobial and antiulcer evaluations of ginger-infused virgin coconut oil by Ibeabuchi Jude Ali, Okorie Ndidiamaka H, Adonu Cyril C, Omeh Romanus C, Obidiegwu Onyeka C, Okonkwo Raymond M, Okafor Judith O, Okoye Festus BC

“…The effect of GIVCO on tested organisms compared favorably to that of standard drugs. …”
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Designing a Policy Making Model in Iran' Sport with the Approach of Sport for All Development by Behdad Sadeghi, Rahmatollah Gholipour, Mojtaba Amiri, Marjan Saffari

“…These experts were either professors or managers of organizations related to sports, possessing over a decade of executive and decision-making experience. …”
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High-performance CT features supporting accurate pre-operative tumor staging in colon cancer by Jianhua Yuan, Cangzheng Jin, Jianrong Si, Baobao Liu, Xiaohan Si, Jianzhi Chen

“…We aimed to pathologically interpret the key CT findings in order to identify reliable markers for pre-treatment staging of colon cancer.Patients and methodsThe following CT features from 136 colon adenocarcinomas were analyzed: colon wall pliability, outline contour, pericolic fat attenuations and vascularity, tumor fusion with adjacent organs, ascites, tumor size, and relevance between tumor and retroperitoneal fascia. …”
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Outcome and Management of Sepsis at RozhHalat Emergency Hospital in Erbil –Kurdistan region of Iraq by Samir Qader Ahmad, Shakawan Muhamad Ismaeel, Dara Ahmed Mohammed Ahmed Mohammed, Halgurd Fathulla Ahmed

“…The qSOFA score is as good as SIRS criteria in predicting mortality. High lactate, multi-organ failure and multisource of infection associated with the worst outcome. …”
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