Comparative genomics reveals low levels of inter- and intraspecies diversity in the causal agents of dwarf and common bunt of wheat and hint at conspecificity of Tilletia caries an... by Somayyeh Sedaghatjoo, Bagdevi Mishra, Monika K. Forster, Yvonne Becker, Jens Keilwagen, Berta Killermann, Marco Thines, Petr Karlovsky, Wolfgang Maier

“…Abstract Tilletia caries and T. laevis, which are the causal agents of common bunt, as well as T. controversa, which causes dwarf bunt of wheat, threaten especially organic wheat farming. The three closely related fungal species differ in their teliospore morphology and partially in their physiology and infection biology. …”
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Development of Novel Oral Delivery Systems Using Additive Manufacturing Technologies to Overcome Biopharmaceutical Challenges for Future Targeted Drug Delivery by Micol Cirilli, Julius Krause, Andrea Gazzaniga, Werner Weitschies, Matteo Cerea, Christoph Rosenbaum

“…The aim was to design, prototype, and evaluate the system’s functionality for organ retention and targeted drug release. <b>Methods:</b> The system was created using 3D printing technologies, specifically FDM and SLA, with materials such as PLA and HPMC. …”
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Cell-free DNA: a metabolic byproduct with diagnostic and prognostic potential in rheumatic disorders by Fancheng Liu, Fancheng Liu, Yazhen Su, Yazhen Su, Xinling Liu, Li Zhao, Li Zhao, Zewen Wu, Zewen Wu, Yang Liu, Yang Liu, Liyun Zhang, Liyun Zhang

“…In healthy people, the levels of cfDNA in the circulation are notably minimal. Within a healthy organism, cfDNA undergoes swift elimination and filtration upon release, ensuring a persistently low concentration in the bloodstream. …”
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Strategic bioprocessing of A. protothecoides and C. sorokiniana using renewable feedstocks for targeted bioproduct and biodiesel generation by Eleni Krikigianni, Kyriakos Antoniadis, Paul Christakopoulos, Ulrika Rova, Leonidas Matsakas, Alok Patel

“…Heterotrophic cultivation of A. protothecoides (AP) and C. sorokiniana (CS) in glucose showed enhanced cell growth with organic N-sources. Biomass was consistently elevated across C/N ratios from 5 to 60 with corn steep liquor (CSL) (8.1 g L-1) and yeast extract (YE) (7.0 g L-1), while with urea it maximized at C/N 5 (6.2 g L-1). …”
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A Toxicological Evaluation of Methylliberine (Dynamine®) by Timothy S. Murbach, Róbert Glávits, John R. Endres, Amy E. Clewell, Gábor Hirka, Adél Vértesi, Erzsébet Béres, Ilona Pasics Szakonyiné

“…In male animals, test item-related effects on body weight and sexual organs, which were not reversible after a 28-day recovery period without treatment, were observed in the high-dose group. …”
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Validation of a paediatric sepsis screening tool to identify children with sepsis in the emergency department: a statewide prospective cohort study in Queensland, Australia by Paula Lister, Kristen Gibbons, Luregn J Schlapbach, Adam Irwin, Michael Rice, Sainath Raman, Amanda Harley, Patricia Gilholm

“…Sensitivity analyses using the outcomes of sepsis-associated organ dysfunction (AUC 0.84, 95% CI 0.81 to 0.87) and septic shock (AUC 0.84, 95% CI 0.81 to 0.88) confirmed the main results.Conclusions A simplified paediatric sepsis screening tool performed well to identify children with sepsis in the ED. …”
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Prevalence of Diarrhea Disease and Associated Factors Among Children Under 5 Years in Geshiyaro Project Implementation Sites in Ethiopia: A Cross‐Sectional Study by Zinabu Assefa Alemu, Aderajew Mekonnen Girmay, Kirubel Tesfaye Teklu, Ermias Alemayehu Adugna, Melaku Gizaw Serte, Tsigereda Assefa Alemayehu, Badasa Wagari Likasa, Benjamin Collyer, Zelalem Mehari, Mihretab Salasibew, Getachew Tollera, Masresha Tessema

“…Therefore, the government and partner organizations should implement effective interventions to increase vaccine coverage and reduce diarrhea.…”
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RNA sequence analysis landscape: A comprehensive review of task types, databases, datasets, word embedding methods, and language models by Muhammad Nabeel Asim, Muhammad Ali Ibrahim, Tayyaba Asif, Andreas Dengel

“…Deciphering information of RNA sequences reveals their diverse roles in living organisms, including gene regulation and protein synthesis. …”
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Humic Acid Enhances Antioxidant and Glyoxalase Systems to Combat Copper Toxicity in Citrus by Wei-Tao Huang, Xu-Feng Chen, Wei-Lin Huang, Qian Shen, Fei Lu, Ning-Wei Lai, Jiuxin Guo, Lin-Tong Yang, Xin Ye, Li-Song Chen

“…Most commercial citrus fruits are grown in acidic soils with high copper (Cu) and low organic matter levels in China. Sweet orange (<i>Citrus sinensis</i> (L.) …”
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Dexmedetomidine Attenuates Monocyte-Endothelial Adherence via Inhibiting Connexin43 on Vascular Endothelial Cells by Yunfei Chai, Runying Yu, Yong Liu, Sheng Wang, Dongdong Yuan, Jimei Chen

“…Current studies have identified the multifaceted protective functions of dexmedetomidine on multiple organs. For the first time, we clarify effects of dexmedetomidine on monocyte-endothelial adherence and whether its underlying mechanism is relative to connexin43 (Cx43), a key factor regulating monocyte-endothelial adherence. …”
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Relevance of plant growth-promoting bacteria in reducing the severity of tomato wilt caused by Fusarium oxysporum f. sp. lycopersici by altering metabolites and related genes by Waquar Akhter Ansari, Ram Krishna, Sarvesh Pratap Kashyap, Khalid Mashay Al-Anazi, Mohammad Abul Farah, Durgesh Kumar Jaiswal, Akhilesh Yadav, Mohammad Tarique Zeyad, Jay Prakash Verma

“…Among the biotic stresses, wilt disease severely affects tomato quality and productivity globally. The causal organism of this disease is Fusarium oxysporum f. sp. lycopersici (Fol), which is very well known and has a significant impact on the productivity of other crops as well. …”
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In silico design of an epitope-based vaccine ensemble for fasliolopsiasis by Ruchishree Konhar, Ruchishree Konhar, Kanhu Charan Das, Kanhu Charan Das, Aiboklang Nongrum, Rohan Raj Samal, Shailesh Kumar Sarangi, Devendra Kumar Biswal, Devendra Kumar Biswal

“…It predominates in school-age children, and significant worm burdens are not uncommon. The causal organism is Fasciolopsis buski, a giant intestinal fluke that infects humans and causes diarrhoea, fever, ascites, and intestinal blockage. …”
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Drivers of methane-cycling archaeal abundances, community structure, and catabolic pathways in continental margin sediments by Longhui Deng, Longhui Deng, Damian Bölsterli, Clemens Glombitza, Bo Barker Jørgensen, Hans Røy, Mark Alexander Lever, Mark Alexander Lever

“…We observe major changes in community structure that largely follow vertical gradients in sulfate concentrations and lateral gradients in organic carbon reactivity and content. While methane-cycling archaeal communities in bioturbated and sulfatic zones are dominated by known methyl-disproportionating Methanosarcinaceae and putatively CO2-reducing Methanomicrobiaceae, the communities change toward dominance of methane-oxidizing taxa (ANME-2a-b, ANME-2c, ANME-1a-b) in sulfate–methane transition zones (SMTZs). …”
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Density functional theory calculation for understanding the roles of biochar in immobilizing exchangeable Al3 + and enhancing soil quality in acidic soils by Debo He, Xinyi Liu, Dongni Hu, Ping Lei, Jinbo Zhang, Zhixin Dong, Bo Zhu

“…Similarly, soils developed from the Cretaceous Jiaguan Formation (K2j) purplish red sandstone with 1 % and 3 % biochar addition showed a 38.75 % and 64.30 % increase in soil organic carbon compared to soils treated with 0.2 % lime. …”
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The importance of genotyping within the climate-smart plant breeding value chain – integrative tools for genetic enhancement programs by Ana Luísa Garcia-Oliveira, Rodomiro Ortiz, Fatma Sarsu, Søren K. Rasmussen, Paterne Agre, Asrat Asfaw, Moctar Kante, Subhash Chander

“…Besides, managers are dealing with a multitude of issues with different organizations working on similar initiatives and projects, leading to a lack of a sustainable impact on smallholder farmers. …”
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The Association of Depression and Anxiety Disorders With Gastrointestinal Symptoms Among Nurses by Behnam Masihipour, Fariborz Mansour-Ghanaei, Saman Maroufizadeh, Soheil Hassanipour, Mehrnaz Asgharnezhad, Adele Isanazar, Kourosh Mojtahedi, Farahnaz Joukar

“…Background: The significant overlap of psychological disorders in both functional and organic gastrointestinal (GI) diseases highlights the complex and interconnected relationship between the brain and the gut.  …”
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Non-thermal atmospheric plasma treatments enhance the growth, photosynthesis, metabolite accumulation, and nutritional value of geranium (Pelargonium graveolens L’Herit) leaves by Hussein S. Mohamed, Dalia Shehata, Ahmed M. Mahmoud, Maha H. Khalaf, Mohammad K. Okla, Mohamed A. El-Tayeb, Yasmeen A. Alwasel, Ibrahim A. Alaraidh, Ali El-Keblawy, Izabela Josko, Mohamed S. Sheteiwy

“…Improved photosynthesis led to enhanced accumulation of primary metabolites, such as amino acids, organic acids, and fatty acids. NTAP treatments, mainly T3, significantly increased levels of essential and non-essential amino acids, oxalic, isobutyric, and fumaric acids. …”
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Ganciclovir Resistance-Linked Mutations in the HCMV <i>UL97</i> Gene: Sanger Sequencing Analysis in Samples from Transplant Recipients at a Tertiary Hospital in Southern Brazil by Anna Caroline Avila da Rocha, Grazielle Motta Rodrigues, Alessandra Helena da Silva Hellwig, Dariane Castro Pereira, Fabiana Caroline Zempulski Volpato, Afonso Luís Barth, Fernanda de-Paris

“…<b>Results:</b> The study sample included various transplants, encompassing solid organ and bone marrow recipients. Among 16 sequenced samples, 8 exhibited nucleotide substitutions resulting in amino acid changes. …”
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Silver Ecotoxicity Estimation by the Soil State Biological Indicators by S. I. Kolesnikov, N. I. Tsepina, L.V. Sudina, T. V. Minnikova, K. Sh. Kazeev, Yu. V. Akimenko

“…The light granulometric composition of sierosands and the acidic reaction of the environment of brown forest soils, as well as the low content of organic matter, contribute to high mobility and, consequently, high ecotoxicity of silver in these soils. …”
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Adaptation variation of easiness on environmental, social, and governance components in the selected sustainability developments by F.R. Sutikno, N.A. Sasongko, I.N. Djarot, H.S. Dillon

“…In the absence of global standards, organizations have developed standardized reporting frameworks for companies. …”
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