Secondary Circulating Prostate Cells Predict Biochemical Failure in Prostate Cancer Patients after Radical Prostatectomy and without Evidence of Disease by Nigel P. Murray, Eduardo Reyes, Nelson Orellana, Cynthia Fuentealba, Leonardo Bádinez, Ruben Olivares, José Porcell, Ricardo Dueñas

“…Age, pathological stage (organ confined, nonorgan confined), pathological grade, margin status (positive, negative), extracapsular extension, perineural, vascular, and lymphatic infiltration (positive, negative) were compared with the presence/absence of CPCs and with and without biochemical failure. …”
Get full text

Age influences the circulating immune profile in pediatric sepsis by Grace Fisler, Grace Fisler, Grace Fisler, Mariana R. Brewer, Mariana R. Brewer, Mariana R. Brewer, Omar Yaipen, Clifford S. Deutschman, Clifford S. Deutschman, Clifford S. Deutschman, Matthew D. Taylor, Matthew D. Taylor, Matthew D. Taylor

“…BackgroundThe immune response changes as patients age, yet studies on the immune dysregulation of sepsis often do not consider age as a key variable.ObjectiveWe hypothesized that age would influence the immune response in septic children and that there would be a distinct variation in the immune profile in healthy children and children with either sepsis, uncomplicated infection, or acute organ dysfunction without infection. We characterized the circulating immune profile of children presenting to our tertiary care children’s hospital.MethodsThis investigation was a prospective, observational cohort study that enrolled patients from July 2020 – September 2022. …”
Get full text

In Situ Modulation of NiFeOOH Coordination Environment for Enhanced Electrocatalytic‐Conversion of Glucose and Energy‐Efficient Hydrogen Production by Ning Wei, Sufeng Zhang, Xue Yao, Qinglu Li, Nan Li, Jinrui Li, Dingjie Pan, Qiming Liu, Shaowei Chen, Scott Renneckar

“…Herein, NiFe‐based metal‐organic framework (MOF) is used as a precursor to prepare W‐doped nickel‐iron phosphide (W‐NiFeP) nanosheet arrays by ion exchange and phosphorylation, which exhibit a high electrocatalytic activity toward the hydrogen evolution reaction (HER), featuring an overpotential of only −179 mV to achieve the current density of 100 mA cm−2 in alkaline media. …”
Get full text

The role of FAM171A2-GRN-NF-κB pathway in TBBPA induced oxidative stress and inflammatory response in mouse-derived hippocampal neuronal HT22 cells by Yi Wang, Jing Shan, Ling Zhang, Rui Wang, Meng-Yu Wu, Hong-Mei Li, Hai-Ming Xu

“…Tetrabromobisphenol A (TBBPA) is one of the brominated flame retardants (BFRs) widely used in industry, which has a broad toxic effect on organisms. However, there is still limited research on the neurotoxic mechanism of TBBPA. …”
Get full text

Differential impacts of water diversion and environmental factors on bacterial, archaeal, and fungal communities in the eastern route of the South-to-North water diversion project by Moran Tang, Qian Chen, Xinzong Xiao, Yitao Lyu, Weiling Sun

“…Notably, only bacterial functional diversity decreased during the WDP, with increased relative abundance of chemoheterotrophic and organic compound catabolic bacteria and declined photoautotrophic bacteria. …”
Get full text

Testing the Purity of <i>Limnospira fusiformis</i> Cultures After Axenicity Treatments by Michael Schagerl, Alexander Kaptejna, Fabian Polz, Sameh S. Ali, Shuhao Huo, Joana Seneca, Petra Pjevac, Vera Hechtl

“…Contaminations are challenging for monocultures, as they impact the culture conditions and thus influence the growth of the target organism and the overall biomass composition. In phycology, axenic cultures comprising a single living species are commonly strived for both basic research and industrial applications, because contaminants reduce significance for analytic purposes and interfere with the safety and quality of commercial products. …”
Get full text

Microbiological hazards associated with the use of water in the post‐harvest handling and processing operations of fresh and frozen fruits, vegetables and herbs (ffFVH). Part 2 – A... by EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Lieve Herman, Liesbeth Jacxsens, Lapo Mughini‐Gras, Maarten Nauta, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Jen Banach, Bin Zhou, Maria Teresa daSilva Felício, Laura Martino, Winy Messens, Angela Botteon

“…Critical variables describing microbial dynamics in water are: (i) the chemical oxygen demand (COD), as an indicator of the concentration of organic matter; (ii) free chlorine (FC) and particularly its antimicrobial fraction, hypochlorous acid (HOCl); and (iii) the microbial population levels. …”
Get full text

Seasonal Variability of PM10 Chemical Composition Including 1,3,5-triphenylbenzene, Marker of Plastic Combustion and Toxicity in Wadowice, South Poland by Przemysław Furman, Katarzyna Styszko, Alicja Skiba, Damian Zięba, Mirosław Zimnoch, Magdalena Kistler, Anne Kasper-Giebl, Stefania Gilardoni

“…Samples were also analyzed for OC/EC (organic/elemental carbon) by thermal-optical analysis with a Sunset Laboratory carbon analyzer, Sunset Inc. …”
Get full text

Intraindividual variation in histone acetylation and its impact on autoimmune thyroid diseases by Emi Haga, Naoya Inoue, Yoshinori Iwatani, Yuya Arakawa, Emi Morita, Hidemi Hashimoto, Yusuke Noguchi, Yoh Hidaka, Mikio Watanabe

“…Autoimmune thyroid diseases (AITDs), such as Graves’ disease (GD) and Hashimoto’s disease (HD), are organ-specific autoimmune diseases. Histone acetylation, especially that of histone H3, is an epigenetic mechanism that regulates gene expression and is associated with the development of autoimmune diseases. …”
Get full text

The N-acetyltransferase 10 inhibitor [11C]remodelin: synthesis and preliminary positron emission tomography study in mice by Rui Luo, Yiding Zhang, Katsushi Kumata, Lin Xie, Yusuke Kurihara, Masanao Ogawa, Tomomi Kokufuta, Nobuki Nengaki, Feng Wang, Ming-Rong R. Zhang

“…Conclusions In the present study, we successfully synthesized [11C]remodelin and assessed its biodistribution of radioactivity in the mouse organs and tissues with PET. We are planning to prepare tumor and inflammatory models in which overexpression of NAT10 is possibly induced and conduct PET imaging for these animal models with [11C]remodelin to elucidate the relationship between NAT10 and diseases.…”
Get full text

Developing Green Marketing Strategies: A Comprehensive Analysis of Consumer Behaviour and Business Practices by Ahmad Mansour, Hind Al-Ahmed, Anan Deek, Khaled Alshaketheep, Mohammad Al-Ma'aitah, Bara Asfour, Muhammad Alshurideh

“…An analysis of Nike, Starbucks, and Toyota, Apple, and Microsoft organizations shows that they incorporate different strategies in supply chain management, carbon footprint, corporations’ responsibility, and customer relations. …”
Get full text

Cloning and expression characterisation of LiDXS2 gene in Oriental Lily (Lilium 'Sorbonne') by Yu Jiaxuan, Wu Nana, Fu Ruyu, Xue Lili, Zhang Jinzhu, Dong Jie, Yang Tao, Fan Jinping

“…In different flowering stages, the expression patterns of LiDXS2 were basically the same as the TranScriptome sequencing results, and the overall trend was initially increasing and then decreasing. In different floral organ tissues, the expression level of LiDXS2 was significantly higher in petals than other tissues, and almost no expression was observed in anthers. …”
Get full text

The Efficacy of Single-Application NPWTi-d for the Salvage of Infected Breast Prostheses: A Multi-Center Study by Jason C. Llaneras, MD, Robert Craig Clark, MD, Lauren Antognoli, MD, Emily Finkelstein, MD, Luci Hulsman, BS, Luther Holton, MD, Devinder Singh, MD, R. Jason VonderHaar, MD, Risal Djohan, MD, Aladdin H. Hassanein, MD, Chris M. Reid, MD

“…Methicillin-resistant organisms were cultured in 15% of cases. NPWTi-d was applied for an average of 61 hours with dwell times of 18 minutes every 3 hours, using institution-specific instillates. …”
Get full text

Knowledge, Attitude, and Practices (KAP) of Human Populations towards Malaria Control in Four Ecoepidemiological Settings in Cameroon by Nelly Armanda Kala Chouakeu, Laura Gilberine Ngingahi, Roland Bamou, Abdou Talipouo, Carmen Sandra Ngadjeu, Marie Paul Audrey Mayi, Edmond Kopya, Parfait Awono-Ambene, Timoléon Tchuinkam, Christophe Antonio Nkondjio

“…Mosquito nets were the most commonly used protective measure against malaria, and the majority of nets in households came from the free-of-charge mass distribution campaigns organized by the government. Participants with secondary and higher levels of education were more aware of good practices towards malaria control compared to those with a primary level of education. …”
Get full text

Risk Factors for Sepsis Based on Sepsis-3 Criteria after Orthotopic Liver Transplantation by Yanling Wang, Yu Gu, Fei Huang, Dezhao Liu, Zheng Zhang, Niman Zhou, Jiani Liang, Changyin Lu, Dongdong Yuan, Ziqing Hei

“…Sepsis is a common complication of solid organ transplant procedures and, in particular, can affect the prognosis of orthotopic liver transplantation (OLT). …”
Get full text

Gene Expression Profile in Delay Graft Function: Inflammatory Markers Are Associated with Recipient and Donor Risk Factors by Diego Guerrieri, Luis Re, Jorgelina Petroni, Nella Ambrosi, Roxana E. Pilotti, H. Eduardo Chuluyan, Domingo Casadei, Claudio Incardona

“…Delayed graft function (DGF) remains an important problem after kidney transplantation and reduced long-term graft survival of the transplanted organ. The aim of the present study was to determine if the development of DGF was associated with a specific pattern of inflammatory gene expression in expanded criteria of deceased donor kidney transplantation. …”
Get full text

Ichthyoarchaeological perspectives on roles of fish and red meat during Indus Civilization in Gujarat, India by G. S. Abhayan, Pramod P. Joglekar, Pramod P. Joglekar, P. Ajithprasad, S. V. Rajesh, Pankaj Goyal, Brad Chase, Jeevan Kharakwal, Prabodh Shirvalkar

“…While significant progress has been made in understanding the domestication and hunting of mammals, information on the use of aquatic organisms such as fish, mollusks, and crustaceans has been relatively sparse. …”
Get full text

The Resuscitation, Equilibrium and De-escalation (RED) strategy: a phased, personalized hemodynamic support in children with sepsis by Jaime Fernández-Sarmiento, Sushitra Ranjit, L. Nelson Sanchez-Pinto, Vinay M. Nadkarni, Roberto Jabornisky, Niranjan Kissoon

“…Our goal with the introduction of this concept is to organize and underscore the fact that the cardiovascular support of sepsis is dynamic and should be adapted to each individual and context.…”
Get full text

Long term effectiveness of intraoperative radiotherapy given as a boost in adjuvant treatment for oral cavity cancers by Grzegorz Woźniak, Tomasz Rutkowski, Wojciech Majewski, Aleksandra Napieralska, Jerzy Wydmański, Agnieszka Czarniecka, Cezary Szymczyk, Adam Bekman, Żaneta Kaniszewska Dorsz, Tomasz Latusek, Bogusław Maciejewski

“…Abstract The oral cancer treatment of choice is surgical excision with an organ preservation, if it is possible. Radiation therapy is commonly used as a postoperative treatment. …”
Get full text

Clinical Research Network: JHCRN Infrastructure and Lessons Learned by Rahul Kashyap, Gayane Yenokyan, Robert Joyner, Melissa Gerstenhaber, Mary Alderfer, Erika Siegrist, Joan Moore, Channing J. Paller, Hanan Aboumatar, James J. Potter, Stanley Watkins Jr, John E. Niederhuber, Daniel E. Ford, Adrian Dobs

“…Designed to leverage organized patient communities, community‐based investigators, and academic researchers, the JHCRN provides expedited research across nine health systems in the mid‐Atlantic region. …”
Get full text