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15741
Red flags to suspect inborn errors of immunity in patients with autoimmune diseases
Published 2024-12-01“…In systemic lupus erythematosus, red flags include age of onset before five years, severe organ involvement, chilblain lesions, and chronic lymphoproliferation. …”
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15742
Characterization of Coelenterazine Analogs for Measurements of Luciferase Activity in Live Cells and Living Animals
Published 2004-01-01“…Coelenterazine (CLZN) is the substrate for a group of bioluminescent enzymes obtained from marine organisms. At present, there are more than 10 commercially available CLZN analogs. …”
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15743
Dye-Sensitized Solar Cells Prepared with Mexican Pre-Hispanic Dyes
Published 2018-01-01“…Synthetic dyes, whether organic or organometallic compounds, have the disadvantage of being expensive. …”
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15744
Lipid Nanoparticles With Fine‐Tuned Composition Show Enhanced Colon Targeting as a Platform for mRNA Therapeutics
Published 2025-01-01“…Compared to LNPs with benchmark composition (b‐LNPs), n‐LNPs containing 30% distearoylphosphatidylcholine (DSPC) are well tolerated following intravenous administration and display natural targeting toward the inflamed colon in dextran sodium sulfate (DSS)‐colitis bearing mice, while de‐targeting clearing organs such as the liver and spleen. Using interleukin‐10‐encoding mRNA as therapeutic cargo, n‐LNPs demonstrated a reduction of pathological burden in colitis‐bearing mice. n‐LNPs represent a starting point to further investigate the influence of LNPs composition on systemic biodistribution, ultimately opening new therapeutic modalities in different pathologies.…”
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15745
Community stakeholder perspectives for empowering EJ initiatives through Public Participation Geographic Information Systems (PPGIS)
Published 2025-01-01“…Through a workshop with representatives from community-based organizations (CBOs), participants learned about PPGIS, NASA remote sensing data, and environmental screening tools. …”
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15746
Recycling of Waste Sludge: Preparation and Application of Sludge-Based Activated Carbon
Published 2018-01-01“…Sludge-based activated carbon (SBAC) materials have high adsorption performance and can effectively remove environmental pollutants including typical organic matter and heavy metals through physical and chemical processes. …”
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15747
Curcumin Attenuation of Wear Particle-Induced Osteolysis via RANKL Signaling Pathway Suppression in Mouse Calvarial Model
Published 2017-01-01“…As expected, CUR markedly reduced the secretion of tumor necrosis factor-α, interleukin- (IL-) 1β, and IL-6 in the calvarial organ culture. Moreover, CUR suppressed osteoclastogenesis and decreased bone resorption in vivo compared with PMMA-stimulated calvaria. …”
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15748
Evaluation of Adrenal Function in Nonhospitalized Patients with Cirrhosis
Published 2017-01-01“…Patients with cirrhosis and advancing hepatic insufficiency may show various degrees of other organ malfunction, including brain, kidney, and lung. …”
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15749
Regulatory role of S1P and its receptors in sepsis-induced liver injury
Published 2025-01-01“…As an immune and metabolic organ, the liver affects the progression and prognosis of sepsis. …”
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15750
Pengalaman Negatif Pendidik Sebaya Kelompok Kunci Lelaki Seks dengan Lelaki dalam Memberikan Layanan Pencegahan HIV
Published 2024-10-01“…This study involved thirty-six peer educators that work in several non-government organizations. Three focus group discussions were conducted in September 2023 to Desember 2023. …”
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15751
Petroleum Hydrocarbon Fingerprints of Water and Sediment Samples of Buffalo River Estuary in the Eastern Cape Province, South Africa
Published 2017-01-01“…Concentrations of TPH in the sediments correlated significantly with organic carbon (OC) in both seasons. TPH and OC levels were slightly lower in summer than in autumn in the two environmental matrices, and the average amount of TPH in the water samples collected from all the sampling stations was generally lower than the EU standard limit of 300 μg/L. …”
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15752
Solo Sonographically Guided PCNL under Spinal Anesthesia: Defining Predictors of Success
Published 2016-01-01“…There was no cases of organ injury or death. Conclusion. Solo ultrasonographically guided PCNL under spinal anesthesia is feasible with an acceptable stone-free rate and complication rate.…”
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15753
Life stage hypothesis modeling determines insect vulnerability during developmental life stages to climate extremes
Published 2025-01-01“…Findings from this study demonstrate the value in assessing a butterfly species' response to short‐term weather variation or long‐term climatic changes at each life stage in order to protect and conserve insects and their interactions with other organisms.…”
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15754
The Effectiveness and Mechanisms of China’s Grain Support Policies in Relation to Grain Yield—An Evaluation of a Wide Range of Policies
Published 2025-01-01“…Thus, we collected and organized grain support policies during the study period according to the government work reports of 31 provinces in China from 2001 to 2022 and applied a two-way fixed-effects model based on the variables constructed using textual analysis to further explore the effects of a range of grain support policies on grain production gains. …”
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15755
High Conductivity of Mg-Doped Al0.3Ga0.7N with Al0.4Ga0.6N/AlN Superlattice Structure
Published 2014-01-01“…The highly conductance of Mg-doped Al0.3Ga0.7N layer using low-pressure metal organic chemical vapour deposition (MOCVD) on Al0.4Ga0.6N/AlN superlattice structure was reported. …”
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15756
Large Gliadin Peptides Detected in the Pancreas of NOD and Healthy Mice following Oral Administration
Published 2016-01-01“…We hypothesized that gluten fragments may cross the intestinal barrier to be distributed to organs other than the gut. If present in pancreas, gliadin could interact directly with the immune system and the beta cells to initiate diabetes development. …”
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15757
lncRNA SNHG14 Plays a Role in Sepsis-Induced Acute Kidney Injury by Regulating miR-93
Published 2021-01-01“…Acute kidney injury (AKI) is a common organ injury in sepsis, which leads to poor prognosis. …”
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15758
The Anti-Inflammatory Cytokine, Interleukin-10, Inhibits Inflammatory Mediators in Human Epithelial Cells and Mouse Macrophages Exposed to Live and UV-Inactivated Chlamydia trachom...
Published 2012-01-01“…Similarly, IL-10 diminished cytokine levels as produced by macrophages exposed to UV-inactivated Chlamydia, suggesting the IL-10-mediated inhibition of cytokines is not restricted to live organisms. Our data imply that IL-10 is an important regulator of the initial inflammatory response to C. trachomatis infection and that further investigations be made into IL-10 use to combat inflammation induced by this bacterium.…”
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15759
Dopamine and 24-Epibrassinolide Upregulate Root Resilience, Mitigating Lead Stress on Leaf Tissue and Stomatal Performance in Tomato Plants
Published 2025-01-01“…It is found in plant organs and induces tolerance against abiotic stresses, including contamination. 24-epibrassinolide (EBR) stimulates metabolism, positively impacting flowering and production. …”
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15760
Dual functional hydrogel of osteoclastic-inhibition and osteogenic-stimulation for osteoporotic bone defect regeneration
Published 2025-04-01“…MBG@D5-Gel holds great potential as an effective organic-inorganic hybrid biomimetic implant material for the treatment of osteoporotic bone defects.…”
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