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15581
Co‐Translational Deposition of N6‐Acetyl‐L‐Lysine in Nascent Proteins Contributes to the Acetylome in Mammalian Cells
Published 2025-01-01“…Acetylated dietary protein is a direct source of AcK that can widely and substantially regulate the acetylome in multiple organs of mice. By analyzing the mechanisms underlying AcK contributing to the acetylome in mammalian cells, it is found that KARS can utilize AcK as an alternative substrate to produce N6‐acetyl‐l‐lysyl‐tRNA. …”
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15582
The Place of Dipeptidyl Peptidase-4 Inhibitors in Type 2 Diabetes Therapeutics: A “Me Too” or “the Special One” Antidiabetic Class?
Published 2015-01-01“…In addition, other cytoprotective effects on other organs/tissues that are involved in serious T2DM complications, including the heart, kidney, and retina, have been increasingly reported. …”
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15583
RNA-Seq-Based Gene Expression Pattern and Morphological Alterations in Chick Thymus during Postnatal Development
Published 2019-01-01“…The thymus is a lobulated unique lymphoid immune organ that plays a critical role in the selection, development, proliferation, and differentiation of T cells. …”
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15584
Application of Liquid Chromatography-Tandem Mass Spectrometry for the Detection of Paralytic Shellfish Poison in Bivalve Shellfish and Its Influencing Factors
Published 2025-01-01“…The major factors affecting matrix effects includes endogenous interferences such as phospholipids and proteins and exogenous interferences such as organic substances and polymer residues in the detection methods. …”
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15585
Acute toxicological and behavioural effects of perfluorohexanoic acid (PFHxA) in the model nematode, Caenorhabditis elegans
Published 2025-04-01“…Importantly, this study is the first to demonstrate the toxic effects of PFHxA in nematodes, suggesting that PFHxA could pose a significant risk to non-target organisms such as C. elegans.…”
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15586
An Emerging Pulmonary Haemorrhagic Syndrome in Dogs: Similar to the Human Leptospiral Pulmonary Haemorrhagic Syndrome?
Published 2010-01-01“…All 15 dogs had massive, pulmonary haemorrhage affecting all lung lobes while haemorrhage in other organs was minimal. Histologically, pulmonary lesions were characterized by acute, alveolar haemorrhage without identifiable vascular lesions. …”
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15587
Potential Pitfalls of the Humanized Mice in Modeling Sepsis
Published 2018-01-01“…Humanized mice are xenotransplant animals in the most general terms. Several organs (e.g., bone marrow mesenchymal cells, endothelium) cannot interact with the grafted human leukocytes effectively due to species specificity. …”
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15588
A Standardized Approach to Quantitative Analysis of Nicotine in e-Liquids Based on Peak Purity Criteria Using High-Performance Liquid Chromatography
Published 2018-01-01“…Additionally, the method has been proven robust and flexible for parameters such as change in flow rate, column oven temperature, and organic phase composition, which proves applicability of the method over wide variety of e-liquids in market.…”
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15589
Quantifying the Volume of Particulate Matter at Bus Stations
Published 2025-02-01“…Particulate matter seriously harms the environment, threatening human health and severely damaging all living organisms. The research purpose is to monitor particle emissions at the bus station in the city of Žilina (Slovakia), amassing data on exhaust emissions released from buses at the station premises. …”
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15590
The Pyrolytic Profile of Lyophilized and Deep-Frozen Compact Part of the Human Bone
Published 2012-01-01“…The aim of the study was to compare the pyrolytic pattern, as an indirect means of the analysis of organic composition of deep-frozen and lyophilized compact part of the human bone. …”
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15591
Islet organoids: a new hope for islet transplantation in diabetes
Published 2025-01-01“…However, it is limited by organ shortage globally and other risk factors. Recent advancements in organoid technology provide transformative solutions for islet regeneration. …”
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15592
Oxidative stress caused by 3-monochloro-1,2-propanediol provokes intestinal stem cell hyperproliferation and the protective role of quercetin
Published 2025-02-01“…Here, we employed the adult intestine of Drosophila melanogaster, a notable invertebrate model organism, to investigate the intestinal toxicity of 3-MCPD and its underlying mechanisms. …”
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15593
Motion-tolerant 3D volumetric multimodality microscopy imaging of human skin with subcellular resolution and extended field-of-view
Published 2025-02-01“…Abstract The skin, the body’s largest organ, has a heterogeneous structure with various cell types and tissue layers. …”
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15594
EFFECTS OF LIME, VERMICOMPOST, AND BLENDED FERTILIZER ON MAIZE (ZEA MAYS L.) POSTHARVEST SELECTED SOIL CHEMICAL PROPERTIES IN ASSOSA DISTRICT, NORTH WESTERN ETHIOPIA
Published 2024-05-01“…The study showed that integrated application of 5 t ha-1 vermicompost with lime increased the pH from 5.27 to 6.03, organic carbon, and total nitrogen from 1.56% and 0.15% to 2.95% and 0.22%, respectively. …”
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15595
Synergistic activity of Pitstop-2 and 1,6-hexanediol in aggressive human lung cancer cells
Published 2025-01-01“…Drug safety and tolerability assessments were validated using the in vivo model organism Caenorhabditis elegans, where fairly high doses showed negligible impact on survival, development, or behavioral parameters. …”
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15596
Evaluating GEMS HCHO Retrievals With TROPOMI Product, Pandora Observations, and GEOS‐Chem Simulations
Published 2025-01-01“…Abstract Satellite column formaldehyde (HCHO) is an indicator of regional volatile organic compounds (VOC) emissions as HCHO is a short‐lived intermediate oxidation product. …”
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15597
Endothelial STAT3 Modulates Protective Mechanisms in a Mouse Ischemia-Reperfusion Model of Acute Kidney Injury
Published 2017-01-01“…In addition, there is a growing appreciation of the role STAT3 signaling plays in response to organ injury following diverse insults. Acute kidney injury (AKI) from ischemia-reperfusion injury is a common clinical entity with devastating consequences, and the recognition that endothelial alterations contribute to kidney dysfunction in this setting is of growing interest. …”
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15598
Study of the Potential Endocrine-Disrupting Effects of Phenylurea Compounds on Neurohypophysis Cells In Vitro
Published 2019-01-01“…If they modify the adaptation of living organisms as direct (e.g., by altering hormone regulation, membrane functions) and/or indirect (e.g., cell transformation mechanisms) factors, they are classified as EDC. …”
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15599
Determination of Land Suitability Criteria for Maize Hybrid in Boalemo Regency Based on Optimum Yield and Selected Land Quality
Published 2023-01-01“…The soil characteristics were effective depth, coarse material, organic C, total N, K exchangeable, slopes, soil erosion, rock outcrops, and surface rocks. …”
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15600
Acute Exposure to Microcystin-Producing Cyanobacterium Microcystis aeruginosa Alters Adult Zebrafish (Danio rerio) Swimming Performance Parameters
Published 2011-01-01“…Microcystins (MCs) are toxins produced by cyanobacteria (blue-green algae), primarily Microcystis aeruginosa, forming water blooms worldwide. When an organism is exposed to environmental perturbations, alterations in normal behavioral patterns occur. …”
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