Selective Binding of Distamycin A Derivative to G-Quadruplex Structure [d(TGGGGT)]4 by Bruno Pagano, Iolanda Fotticchia, Stefano De Tito, Carlo A. Mattia, Luciano Mayol, Ettore Novellino, Antonio Randazzo, Concetta Giancola

“…Quadruplex-prone sequences are found in many regions of human genome and in the telomeres of all eukaryotic organisms. Since small molecules that target G-quadruplexes have been found to be effective telomerase inhibitors, the identification of new specific ligands for G-quadruplexes is emerging as a promising approach to develop new anticancer drugs. …”
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Global perspectives in acute and emergency general surgery in low and middle-income countries: a WSES project protocol for scoping review on global surgery by Mahmoud Diaa Hindawi, Arda Isik, Fausto Rosa, Diego Visconti, Taras Nechay, Sharfuddin Chowdhury, Abdourahmane Ndong, Tushar S. Mishra, Stefano Piero Bernardo Cioffi, Francesco Piscioneri, Edward C.T.H. Tan

“…Global initiatives have been launched, including efforts led by organizations. Also, regional efforts have shed light on the unique challenges faced by different areas within LMICs. …”
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Towards Sensor-Based Health Monitoring Systems for Bridge Decks: A Full-Depth Precast Deck Panels Case Study by Osama Y. Abudayyeh, Joseph Barbera, Ikhlas Abdel-Qader, Hubo Cai, Eyad Almaita

“…The paper presents a practical case study that mainly focuses on describing the initial steps in the development of the sensor network system, namely, the design (system architecture and data structures) and construction along with examples of how the data is acquired, organized, presented, and analyzed, keeping in mind that the bridge is still early in its life-cycle and has not yet experienced any structural problems.…”
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ILC2 Proliferated by IL-33 Stimulation Alleviates Acute Colitis in Rag1-/- Mouse through Promoting M2 Macrophage Polarization by Yong You, Xiaoqing Zhang, Xiao Wang, Dan Yue, Fanxiang Meng, Junfeng Zhu, Yuanyuan Wang, Xun Sun

“…This study was to identify functions of ILC2, a newly found innate lymphoid cell which mainly locates in mucosa organs like lungs and intestines, in IBD. We injected rIL-33 protein to C57/BL6 mouse to explore how IL-33 induces ILC2 proliferation. …”
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Evaluating the Progress of the EU Countries Towards Implementation of the European Green Deal: A Multiple Criteria Approach by Giovanni Ottomano Palmisano, Lucia Rocchi, Lorenzo Negri, Lea Piscitelli

“…The PROMETHEE II method was applied to the data for EU countries, using 26 key indicators collected from the Eurostat database and organized into three thematic clusters. The results enabled us to calculate overall scores measuring the degree of implementation of the EGD by the EU countries, and their profiles with respect to the key indicators and thematic clusters. …”
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Polystyrene microplastics disrupt adrenal steroid synthesis in male mice via mitochondrial dysfunction by Ying Xiong, Zhe Chen, Hanmin Xiang, Yi Liu, Yanlin Wang

“…The latter may represent a common mechanism underlying the multi-organ toxicity induced by PS-MPs in the body. Our findings would provide new insights for the development of more effective environmental protection measures and the reduction of plastic pollution.…”
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PEPITEM, its tripeptide pharmacophores and their peptidomimetic analogues regulate the inflammatory response through parenteral and topical dosing in models of peritonitis and psor... by Anella Saviano, Bonita Apta, Samantha Tull, Laleh Pezhman, Areeba Fatima, Mustafa Sevim, Antonio Mete, Myriam Chimen, Anna Schettino, Noemi Marigliano, Helen M. McGettrick, Asif J. Iqbal, Francesco Maione, G. Ed Rainger

“…Th1 and Th17 cell abundance, along with their cytokines, was reduced in secondary lymphoid organs. This expanded functional repertoire of PEPITEM and its derivatives provides innovative tools for countering immune and stromal cell-induced pathology in IMIDs. …”
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Establishment of an animal model for monkeypox virus infection in dormice by Gaojie Song, Lingling Cheng, Jun Liu, Yu Zhou, Cuiling Zhang, Yuping Zong

“…Virological tests further confirmed the distribution of MPXV in multiple vital organs of dormice, including the lungs, liver, spleen, and trachea, with particularly significant pathological damage observed in lung tissue. …”
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Particle-size fractions-dependent extracellular enzyme activity in sediments and implications for resource allocation in a subtropical mangrove ecosystem by L. Luo, J.-D. Gu

“…Thus, these results provided a means to assess the availability of different nutrients (C, N, and P) during decomposition of sediment organic matter (SOM), and thus helping to better manage the subtropical mangrove ecosystems to sequester C into SOM.…”
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Catalase Biomimetic Sensor Based on Metal by Malikova Nurana Nahmad, Gurbanova Lala Maharram, Ali-Zadeh Nahmad Islam, Nagiev Tofik Murtuza, Shokhzod Ulashov, Kurbanova Shaxnoza

“…Chemical reactions in living organisms are carried out with the help of catalysts - enzymes. …”
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Reimagining recruitment: traditional methods meet AI interventions- A 20-year assessment (2003–2023) by Aaradhana Rukadikar, Komal Khandelwal, Uma Warrier

“…By incorporating AI-assisted recruiting tools, emphasizing user-centered design, and allocating resources to artificial intelligence, organizations can improve their decision-making process. …”
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Safety and efficacy of long-term nicotinamide mononucleotide supplementation on metabolism, sleep, and nicotinamide adenine dinucleotide biosynthesis in healthy, middle-aged Japane... by Shintaro Yamaguchi, Junichiro Irie, Masanori Mitsuishi, Yuichi Uchino, Hideaki Nakaya, Ryo Takemura, Emi Inagaki, Shotaro Kosugi, Hideyuki Okano, Masato Yasui, Kazuo Tsubota, Kaori Hayashi, Jun Yoshino, Hiroshi Itoh

“…Accumulating evidence from both rodents and humans suggests that the levels of nicotinamide adenine dinucleotide (NAD+), a regulator of many biological processes, declines in multiple organs and tissues with aging and obesity. Administration of an NAD+ intermediate, nicotinamide mononucleotide (NMN), replenishes intracellular NAD+ levels and mitigates aging- and obesity-associated derangements in animal models. …”
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Maternal Dietary Patterns and Gestational Diabetes Risk: A Case-Control Study by Fatemeh Sedaghat, Mahdieh Akhoondan, Mehdi Ehteshami, Vahideh Aghamohammadi, Nila Ghanei, Parvin Mirmiran, Bahram Rashidkhani

“…Western dietary pattern was high in sweets, jams, mayonnaise, soft drinks, salty snacks, solid fat, high-fat dairy products, potatoes, organ meat, eggs, red meat, processed foods, tea, and coffee. …”
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Bench Scale Treatability Studies of Contaminated Soil Using Soil Washing Technique by M. K. Gupta, R. K. Srivastava, A. K. Singh

“…In the present study soil washing technique using plain water with surfactants as an enhancer was used to study the remediation of soil contaminated with (i) an organic contaminant (engine lubricant oil) and (ii) an inorganic contaminant (heavy metal). …”
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Introduction of Vector-Borne Infections in Europe: Emerging and Re-Emerging Viral Pathogens with Potential Impact on One Health by Jacopo Logiudice, Maria Alberti, Andrea Ciccarone, Benedetta Rossi, Giorgio Tiecco, Maria Antonia De Francesco, Eugenia Quiros-Roldan

“…Europe faces increased risk due to the expanding habitats of disease-carrying organisms, the spread of new species like <i>Aedes albopictus</i> since 2013, and increased movement of infected individuals between countries, leading European countries to implement strategies such as enhanced surveillance systems, public awareness campaigns, and prompt outbreak response strategies. …”
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International University Network Internet Project of Integrated Engineering Education by I. V. Breido, S. M. Stazhkov, A. V. Bobryakov, V. G. Khomchenko, A. A. Kabanov, B. Katalinic

“…The laboratories of the project participants are equipped with modern training stands and multimedia tools for conducting on-line courses and laboratory work in the remote access mode produced by the leading domestic and foreign companies including world leaders in the field of automation and robotics Festo, Siemens, Mitsubishi Auto Electrician.Regular online training has been organized with the use of exchange, composite and embedded module courses. …”
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A case of kidney graft injury during cesarean section in a pancreas and kidney transplantation recipient by Noriko Aida, Eiji Nishio, Takao Sekiya, Naohiro Aida, Taihei Ito, Takashi Kenmochi, Haruki Nishizawa

“…Although organ transplantation is becoming general practice, little is known about the safety of delivery. …”
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Bladder Tumor in Women with Microscopic Hematuria: An Iranian Experience and a Review of the Literature by Shahin Abbaszadeh, Saeed Taheri, Mohammad Hossein Nourbala

“…Patients with a history of gross hematuria or coagulation disorders, having organic diseases, urinary stones, urinary tract infections, nephrological diseases, and local lesions such as urethral caruncle were excluded from the study population. …”
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OCCUPATIONAL HEALTH AND SAFETY PRACTICES IN THE WORKPLACE DURING THE COVID-19 PANDEMIC: A LITERATURE REVIEW by Ana Islamiyah Syamila, Reny Indrayani, Ragil Ismi Hartanti, Anita Dewi Prahastuti Sujoso

“…Background: The Corona Virus Disease 2019 (COVID-19) pandemic, which has impacted the world of work, has necessitated work organizations to prevent transmission and enhance workers’ performance. …”
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Etiology and Outcomes of ARDS in a Rural-Urban Fringe Hospital of South India by Tarun George, Stalin Viswanathan, Ali Hasan Faiz Karnam, Georgi Abraham

“…Nonsurvivors were generally older, had shorter duration of illness, a nontropical infection, and higher total WBC counts, required longer duration of ventilation, and had other organ dysfunction and higher mean APACHE scores. …”
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