Marine natural products as a source of novel anticancer drugs: an updated review (2019–2023) by Hesham R. El-Seedi, Mohamed S. Refaey, Nizar Elias, Mohamed F. El-Mallah, Faisal M. K. Albaqami, Ismail Dergaa, Ming Du, Mohamed F. Salem, Haroon Elrasheid Tahir, Maria Dagliaa, Nermeen Yosri, Hongcheng Zhang, Awg H. El-Seedi, Zhiming Guo, Shaden A. M. Khalifa

“…With a focus on recent research findings, the review explores the rich biodiversity of marine organisms, including sponges, corals, algae, and microorganisms, which have yielded numerous compounds exhibiting promising anticancer properties. …”
Get full text

Prevalence of dental caries among different stage students in College of Dentistry, Hawler Medical University. by Mahmood Fawzi Abdul‐Jabbar, Blend Hussein Mohammad, Mansour Hadi Mohammad

“… Background and Objectives: Dental caries considered as one of the most prevalent diseases affecting teeth. Many organizations are trying to prevent this disease in a variety of ways. …”
Get full text

Prepartum Vaccination Against Neonatal Calf Diarrhea and Its Effect on Mammary Health and Milk Yield of Dairy Cows: A Retrospective Study Addressing Non-Specific Effects of Vaccina... by Caroline Kuhn, Holm Zerbe, Hans-Joachim Schuberth, Anke Römer, Debby Kraatz-van Egmond, Claudia Wesenauer, Martina Resch, Alexander Stoll, Yury Zablotski

“…Further research is recommended to investigate potential non-specific vaccine effects on other organ systems, infectious diseases, and production metrics of the dairy cow.…”
Get full text

Pioneering the Security of EHRs Using an Immersive Blockchain Conceptual Framework by Rihab Benaich, Youssef Gahi, Saida El Mendili

“…Decentralized Autonomous Organizations (DAOs) are incorporated to decentralize control and reinforce security, while artificial intelligence and metaverse integration facilitate user engagement and streamline operations. …”
Get full text

A Mathematical Pressure Transient Analysis Model for Multiple Fractured Horizontal Wells in Shale Gas Reservoirs by Yan Zeng, Qing Wang, Zhengfu Ning, Hongliang Sun

“…However, the existing models have neglected the percolation mechanism in nanopores of organic matter and failed to consider the differences among the reservoir properties in different areas. …”
Get full text

Physical Activity Protects the Human Brain against Metabolic Stress Induced by a Postprandial and Chronic Inflammation by Leo Pruimboom, Charles L. Raison, Frits A. J. Muskiet

“…Although the notion that increased physical activity would improve health in the modern world is widespread, here we provide a novel perspective on this truism by providing evidence that recovery of normal human behaviour, such as spontaneous physical activity, would calm proinflammatory activity, thereby allocating more energy to the brain and other organs, and by doing so would improve human health.…”
Get full text

Origin of the MRI Contrast in Natural and Hydrogel Formulation of Pineapple Juice by Domenico Rizzo, Enrico Ravera, Marco Fragai, Giacomo Parigi, Claudio Luchinat

“…Magnetic resonance imaging (MRI) often requires contrast agents to improve the visualization in some tissues and organs, including the gastrointestinal tract. In this latter case, instead of intravascular administration, oral agents can be used. …”
Get full text

Application of Physiologically Based Pharmacokinetic Models in Chemical Risk Assessment by Moiz Mumtaz, Jeffrey Fisher, Benjamin Blount, Patricia Ruiz

“…This process is increasingly adopting “in silico” tools such as physiologically based pharmacokinetic (PBPK) models to fine-tune exposure assessments and determine internal doses in target organs/tissues. Many excellent PBPK models have been developed. …”
Get full text

Surgical Tips in Frozen Abdomen Management: Application of Coliseum Technique by Ioannis D. Kyriazanos, Dimitrios K. Manatakis, Nikolaos Stamos, Christos Stoidis

“…Lifting the edges of the surgical wound upwards and suspending them under traction by threads from a retractor positioned above the abdomen facilitates approach to the peritoneal cavity, optimizes exposure of intra-abdominal organs, and prevents operative injury to the innervation and blood supply of abdominal wall musculature, a crucial step for subsequent hernia repair.…”
Get full text

The NLRP3 Inflammasome as a Novel Player of the Intercellular Crosstalk in Metabolic Disorders by Elisa Benetti, Fausto Chiazza, Nimesh S. A. Patel, Massimo Collino

“…The goal of this paper is to review new insights on the effects of the NLRP3 inflammasome activation in the complex mechanisms of crosstalk between different organs, for a better understanding of the role of chronic inflammation in metabolic disease pathogenesis. …”
Get full text

Notch Regulation of Hematopoiesis, Endothelial Precursor Cells, and Blood Vessel Formation: Orchestrating the Vasculature by Vincenza Caolo, Daniel G. M. Molin, Mark J. Post

“…The development of the vascular system begins with the formation of hemangioblastic cells, hemangioblasts, which organize in blood islands in the yolk sac. The hemangioblasts differentiate into hematopoietic and angioblastic cells. …”
Get full text

Isolation of <i>Bacillus paralichenifromis</i> BL-1 and Its Potential Application in Producing Bioflocculants Using Phenol Saline Wastewater by Tao Zhang, Rongkai Guo, Fanshu Liu, Lei Zhang, Linxiao Li, Rongfei Zhang, Chaogang Shao, Junbo Zhou, Fan Ding, Lan Yu

“…Phenolic compounds are harmful organic pollutants found in wastewater from the chemical and pharmaceutical industries, which are frequently accompanied by high saline concentrations. …”
Get full text

Abdominal Compartment Syndrome Secondary to Chronic Constipation by Helene Flageole, Jodie Ouahed, J. Mark Walton, Yasmin Yousef

“…Abdominal compartment syndrome (ACS) is defined as an elevated intraabdominal pressure with evidence of organ dysfunction. The majority of published reports of ACS are in neonates with abdominal wall defects and in adults following trauma or burns, but it is poorly described in children. …”
Get full text

Adipokines as Drug Targets in Diabetes and Underlying Disturbances by Vinícius Andrade-Oliveira, Niels O.S. Câmara, Pedro M. Moraes-Vieira

“…White adipose tissue is recognized as a multifactorial organ that secretes several adipose-derived factors that have been collectively termed “adipokines.” …”
Get full text

Flow chemistry-enabled asymmetric synthesis of cyproterone acetate in a chemo-biocatalytic approach by Yajiao Zhang, Minjie Liu, Xianjing Zheng, Liang Gao, Li Wan, Dang Cheng, Fener Chen

“…Abstract Flow chemistry has many advantages over batch synthesis of organic small-molecules in terms of environmental compatibility, safety and synthetic efficiency when scale-up is considered. …”
Get full text

Endometriosis-Associated Massive Ascites in an Asian Woman: A Case Report of a Rare Clinical Entity by Nuntasiri Eamudomkarn, Naratassapol Likitdee, Pilaiwan Kleebkaow, Chumnan Kietpeerakool

“…The patient underwent exploratory laparotomy which revealed a large amount of serosanguinous ascites, thickened matted bowel loops, and necrotic debris covering the entire surface of the peritoneum and visceral organs. The surgical procedures included drainage of 6.5 liters of ascites, lysis adhesion, biopsy of the peritoneum, and right salpingo-oophorectomy. …”
Get full text

Monitoring the Number of Pedestrians in an Area: The Applicability of Counting Systems for Density State Estimation by D. C. Duives, W. Daamen, S. P. Hoogendoorn

“…Crowd monitoring systems are more and more used to support crowd management organizations. Currently, counting systems are often used to provide quantitative insights into the pedestrian traffic state, since they are fairly easy to install and the accuracy is reasonably good under normal conditions. …”
Get full text

Nosocomial Isolates and Their Drug Resistant Pattern in ICU Patients at National Institute of Neurological and Allied Sciences, Nepal by Pashupati Bhandari, Ganesh Thapa, Bharat Mani Pokhrel, Dwij Raj Bhatta, Upendra Devkota

“…Multidrug resistant organisms are increasing day by day and the cause is poorly known. …”
Get full text

Sewage Sludge Amendment Combined with Green Manuring to a Coastal Mudflat Salt-Soil in Eastern China: Effects on Soil Physicochemical Properties and Maize Yield by Yanchao Bai, Wengang Zuo, Yiyun Yan, Chuanhui Gu, Yongxiang Guan, Lijuan Mei, Weijie Xue, Yuhua Shan, Ke Feng

“…Sewage sludge and green manure have become widely used organic amendments to croplands in many regions of the world. …”
Get full text

Natural Enrichment of Trace Elements in Surface Horizons of Calcareous Soils (La Mancha, Spain) by Sandra Bravo Martín-Consuegra, Jose A. Amorós Ortíz-Villajos, Caridad Pérez-de-los-Reyes, Francisco J. García Navarro, Rolando Ruedas Luna, Raimundo Jiménez Ballesta

“…The geochemical characterization of the aforementioned profiles involves a study of the contents of major and trace elements among other pedologic aspects (texture, pH, organic matter, etc.). The results of this study also indicate a superficial enrichment of trace elements due to the leaching of Ca and moderate biological and anthropic activity. …”
Get full text