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Metabolomics to Identify Unclassified Uremic Toxins: A Comprehensive Literature Review
Published 2025-03-01Get full text
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24264
The dynamin-related protein PfDyn2 is essential for both apicoplast and mitochondrial fission in Plasmodium falciparum
Published 2025-01-01“…PfDyn2’s singular role in mediating both apicoplast and mitochondrial fission has not been observed in other organisms possessing two endosymbiotic organelles, including other Apicomplexans, thus reflecting a unique, potentially exploitable method of organellar division in P. falciparum.IMPORTANCEPlasmodium falciparum remains a significant global pathogen, causing over 200 million infections and over 600,000 deaths per year. …”
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24265
Geophysical and geotechnical assessment of Obiaruku-Agbor road failure in Western Niger-Delta, Nigeria
Published 2025-01-01“…It is consequently advised that a well-designed, organized drainage system be built and that the soils be stabilized or replaced with materials that adhere to standards.The results of this inquiry will be useful in the repair and rehabilitation of the road's deteriorating sections and it is recommended that a thorough record of this study be kept for future reference. …”
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24266
Controlled bottom-up synthesis and characterization of crystalline and amorphous lead(II) coordination polymers: Sonochemical methods, structure–property relationship, and photocat...
Published 2025-03-01“…Single-crystal X-ray diffraction (SC-XRD) was used to investigate two crystallized metal–organic frameworks (MOFs) with the same space group and chemical formula (P21/c). …”
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24267
Iron(III)–Quercetin Complex: In Vivo Acute Toxicity and Biodistribution of Novel MRI Agent
Published 2025-01-01“…Acute toxicity studies showed no mortality, morbidity, or significant biochemical changes, with histopathology confirming no irreversible organ damage. Pharmacokinetics revealed peak blood iron content at 1.1 hours post-administration and clearance within 24 hours. …”
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24268
The Rickettsia actin-based motility effectors RickA and Sca2 contribute differently to cell-to-cell spread and pathogenicity
Published 2025-02-01“…We observed that RickA is important for severe eschar formation, whereas Sca2 contributes to larger foci of infection in the skin and dissemination from the skin to the internal organs. Our results suggest that actin-based motility effectors RickA and Sca2 drive two distinct forms of cell-to-cell spread and contribute differently to pathogenicity in the mammalian host.IMPORTANCERickettsia parkeri, a bacterium in the spotted fever group of Rickettsia species, can be transmitted from ticks to humans, leading to symptoms including fever, rash, muscle aches, and a lesion at the site of the tick bite. …”
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24269
Neutrophil-to-lymphocyte, platelet-to-lymphocyte ratios and systemic immune-inflammation index in patients with post-traumatic stress disorder
Published 2024-12-01“…Exclusion criteria were as follows: presence of PTSD symptoms shorter than one month, presence of psychiatric comorbidity, being diagnosed with psychotic disorder, bipolar disorder, autism spectrum disorder, presence of mental retardation, being under psychotropic drug treatment, presence of a neurological disease that may cause serious disability (epilepsy, cerebrovascular disease), migraine, presence of organic brain damage, smoking, alcohol and substance use disorder, presence of a chronic disease such as diabetes mellitus, hypertension, hyperlipidemia, chronic lung diseases, being in pregnancy and breastfeeding, presence of heart disease were determined as exclusion criteria. …”
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Comparison of positive BioFire FilmArray meningitis/encephalitis (ME) panels, CSF cultures, CSF parameters, clinical presentation and in-patient mortality among patients with bacte...
Published 2025-02-01“…The positive predictive value (PPV) varied by organism, with the highest being Listeria monocytogenes and Neisseria meningitidis. …”
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24271
Anogenital distance in water buffalo females and relationship with reproductive performance. Preliminary results
Published 2023-11-01“…This fact could be attributed to the adverse effects of prenatal exposure to androgens on reproductive organs and endocrine pathways; however, more research is needed to understand this better. …”
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24272
Activation of ClO<sub>2</sub> by Nanoscale Zero-Valent Iron for Efficient Soil Polycyclic Aromatic Hydrocarbon Degradation: New Insight into the Relative Contribution of Fe(IV) and...
Published 2025-01-01“…This study offers new perspectives for the remediation of organic-pollutant-contaminated soil by using metal-activated ClO<sub>2</sub> technology.…”
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Tetrazenyl-, Imido-, and Azidoaluminate Derivatives of a Sterically Demanding Bis-Silazide Ligand
Published 2025-01-01“…The potassium alumanyl [{SiN<sup>Dipp</sup>}AlK]<sub>2</sub> (SiN<sup>Dipp</sup> = {CH<sub>2</sub>SiMe<sub>2</sub>NDipp}<sub>2</sub>; Dipp = 2,6-<i>i</i>-Pr<sub>2</sub>C<sub>6</sub>H<sub>3</sub>) reacts with organic azides via reductive N<sub>2</sub> elimination. …”
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Comparison between traditional logistic regression and machine learning for predicting mortality in adult sepsis patients
Published 2025-01-01“…Model validation and comparison with the Sequential Organ Failure Assessment (SOFA) and the Acute Physiology and Chronic Health Evaluation (APACHE) scores were performed using receiver operating characteristic (ROC) curves, calibration curves, and decision curve analysis (DCA) curves in the validation set.ResultsUnivariate analysis was employed to assess 17 variables, namely gender, history of coronary heart disease (CHD), systolic pressure, white blood cell (WBC), neutrophil count (NEUT), lymphocyte count (LYMP), lactic acid, neutrophil-to-lymphocyte ratio (NLR), red blood cell distribution width (RDW), interleukin-6 (IL-6), prothrombin time (PT), international normalized ratio (INR), fibrinogen (FBI), D-dimer, aspartate aminotransferase (AST), total bilirubin (Tbil), and lung infection. …”
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Enrichment of electrotrophic microorganisms from contrasting shallow-sea hydrothermal environments in bioelectrochemical reactors
Published 2025-02-01“…Most reactors produced organic acids (up to 2.9 mM in 6 days). Still, coulombic efficiencies indicated that this might have been due to the (electro) fermentation of traces of yeast extract in the medium rather than CO2 fixation. …”
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A Cu(I)-Based MOF with Nonlinear Optical Properties and a Favorable Optical Limit Threshold
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24278
Long-term impact of different prevalent cropping systems on soil physico-chemical characteristics under subtropical climate conditions of Punjab, Pakistan
Published 2025-01-01“…A total of 470 georeferenced soil samples were collected using a random survey approach, and the samples were analyzed for soil texture, pH, electrical conductivity (EC), organic matter percentage (OM), total nitrogen percentage (TN), accessible phosphorus (AvP) (mg kg−1) and extractable potassium (ExK) (mg kg−1). …”
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Extent, Distribution, and Causes of Soil Acidity under Subsistence Farming System and Lime Recommendation: The Case in Wolaita, Southern Ethiopia
Published 2021-01-01“…It is concluded that soil management interventions such as maintaining and incorporating crop residues, integrated use of organic and inorganic fertilizers, liming, and enhancing farmers’ awareness should be advocated to overcome soil acidification and improve soil fertility. …”
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Effect of Geographic Regions on the Flavor Quality and Non-Volatile Compounds of Chinese Matcha
Published 2025-01-01“…A total of 1131 differential metabolites were identified in the matcha samples, comprising 118 flavonoids, 14 tannins, 365 organic acids, 42 phenolic acids, 22 alkaloids, 39 saccharides, 208 amino acids and derivatives, 17 lignans and coumarins, seven quinones, 44 nucleotides and derivatives, 14 glycerophospholipids, two glycolipids, 15 alcohols and amines, 140 benzenes and substituted derivatives, 38 terpenoids, 30 heterocyclic compounds, and 15 lipids. …”
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