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23681
Built environment change for injury prevention: insights from public health professionals across public health units in Ontario, Canada
Published 2025-01-01“…Thematic analysis was used to organize and code the data in relation to the guiding principles of the Ontario Public Health Standards (OPHS), situating our results within the broader context of public health and road-related injury prevention in Ontario. …”
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23682
The XIAP inhibitor AZD5582 improves the treatment effect of microwave ablation on hepatocellular carcinoma
Published 2025-01-01“…The low toxicity of AZD5582 was further confirmed through hematological and pathological examinations of vital organs. These results provide new clues for hepatocellular carcinoma treatment, suggesting the potential role of XIAP inhibitors in hepatocellular carcinoma treatment and their impact in immunomodulation.ConclusionsIn this study, we found that the XIAP inhibitor AZD5582 modulates the immune microenvironment and inhibits the progression of post-ablation residual hepatocellular carcinoma.…”
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23683
Development and validation of an LC-MS/MS method for the simultaneous estimation of tadalafil and macitentan in rat plasma: Greenness assessment and design of experiment approach
Published 2025-03-01“…Optimization of critical parameters, including organic phase composition (50% acetonitrile), flow rate (1.0 mL/min), and pH (3.2), was achieved using a Box-Behnken Design, ensuring accurate separation and quantification. …”
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23684
The concept of natural genome reconstruction. Part 1. Basic provisions of the “natural genome reconstruction” concept. Changing the genome of hematopoietic stem cells using several...
Published 2024-11-01“…It is assumed that as a result of stochastic acts of homologous exchange, chromosome loci are corrected in hematopoietic stem cells that have acquired mutations during the existence of the organism, which are the cause of clonal hematopoiesis associated with old age. …”
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23685
Enhancing physical fitness through Crossfit for 15-16-year-old high school students
Published 2024-06-01“…At the same time, restrictions imposed by military actions require different approaches to organizing CrossFit sessions. The most acceptable solution in such a situation is online education and training. …”
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23686
lncRNA-KCNQ1OT1: A Potential Target in Exosomes Derived from Adipose-Derived Stem Cells for the Treatment of Osteoporosis
Published 2021-01-01“…Exosomes derived from adipose-derived stem cells (ADSCs-Exos) have been confirmed to play effective roles in the repair of various tissues and organs. This study was aimed at investigating the role of ADSCs-Exos and a novel long noncoding RNA KCNQ1OT1 played in osteoporosis as well as the underlying mechanism. …”
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23687
To Investigate the Associations of Dyslipidemia and BMI, as Risk Factors Leading to Insulin Resistance and Development of Type2 Diabetes Mellitus in Baqubah City
Published 2022-09-01“…Obesity, particularly visceral fat (fat surrounding the organs) is a major cause of insulin resistance. The homeostasis model evaluation is the gold standard method for determining whether or not a person is insulin resistant. …”
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23688
Le statut de l'oralité dans l'enseignement-apprentissage des langues
Published 2016-11-01“…Le traitement réservé à la matière phonique dans l’enseignement des langues étrangères, et la notion même de langue orale sur laquelle se fondent ces approches révèlent cependant que, dans le meilleur des cas, l’oralité est réduite et circonscrite au flux phonique et/ou à l’activité des organes du tractus phonatoire. Or, d’innombrables phénomènes de parole (variabilité phonique, rythme, métaphonie, macromotricité, modalités énonciatives, proprioception, etc.) témoignent de ce que les manifestations phoniques sont générées dans le processus du dire bien avant qu’elles soient produites dans le tractus phonatoire, et avant que se structure le flux phonique en phonèmes : le processus de parole s’amorce dans une phase prélinguistique et est régi par la « Logique du vivant ». …”
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23689
A Pilot Study on Cognitive Processing Characteristics and Cerebral Mechanisms of Native Chinese-Speaking Savant Calendar Calculators with Autism Spectrum Disorder
Published 2024-04-01“…The patient with SCC was examined with crainial MRI and compared with healthy subjects to explore the organic brain damage.Results(1) Calendar calculation ability test: the correct rate of random normal calendar calculation in the SCC patient was 80%, and the average time of answering each question was 11.8 s, while the average correct rate of random normal calendar calculation in the healthy subjects was only 16%. (2) Calendar memorizing ability test: the correct rate of the adjusted new calendar calculation in the SCC patient was only 20%. (3) Numerical calculation ability: the correct rate of addition and division in the SCC patient was 100%, and the average time was 10.67 s and 58.19 s respectively. …”
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23690
Extracellular electron shuttles induced transformation and mobilization of Fe/As with the occurrence of biogenic vivianite
Published 2025-01-01“…Microorganisms that utilize organic matter to reduce Fe oxides/hydroxides constitute the primary geochemical processes controlling the formation of high-arsenic (As) groundwater. …”
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23691
The role of the Kazan school of journalistic education in the training of national journalists
Published 2017-06-01“…It has been demonstrated that the university has long-established traditions within the field of training specialists in national journalism, which are associated with such outstanding organizers of journalistic science and practice as I.G. …”
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23692
Health Disparities in Rheumatology in the United States
Published 2025-01-01“…Possible solutions include partnerships between healthcare systems and community-based organizations, targeted outreach tailored to patients with low SES, interventions to improve patient adherence and knowledge, and interventions to improve access to care for rural-residing and unhoused patients. …”
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23693
The Effects of Employee Performance Appraisal on the Company Performance Results: The Mediating Role of HRM Outcomes With an Innovative Application of the Efficiency Index
Published 2023-01-01“…This suggests that the EPA used such solutions in conjunction with other HRM subfunctions that stimulated entrepreneurial, creative and innovative behavior of employees in such a way that organizations could achieve better innovation results during the crisis than before it. …”
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23694
Effects of green manuring on chemical characteristics and microecology of tobacco-growing soil in central henan
Published 2025-01-01“…Results The results showed improved soil nutrition and increased organic matter, nitrate-nitrogen, and ammonium-nitrogen levels. …”
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23695
Novel lncRNA LncMSTRG.11341.25 Promotes Osteogenic Differentiation of Human Bone Marrow Stem Cells via the miR-939-5p/PAX8 Axis
Published 2025-01-01“…These findings deepen our understanding of the regulatory role of lncRNA–miRNA–mRNA networks in the immune microenvironment of bone marrow, and highlight the important role played by the spleen as an immune organ in fracture healing.…”
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23696
Tubular MYDGF Slows Progression of Chronic Kidney Disease by Maintaining Mitochondrial Homeostasis
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23697
Detection of Aspergilloma Disease Using Feature-Selection-Based Vision Transformers
Published 2024-12-01“…<b>Background</b>: Aspergilloma disease is a fungal mass found in organs such as the sinuses and lungs, caused by the fungus <i>Aspergillus</i>. …”
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23698
Low regulatory T-cells frequency is associated with graft rejection after small bowel transplantation: Clinical and experimental evidence.
Published 2025-01-01“…Nevertheless, its rejection rate surpasses that of other solid organ transplants due to the heightened immunological load of the gut. …”
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23699
Growth Propagation of Liquid Spawn on Non-Woven Hemp Mats to Inform Digital Biofabrication of Mycelium-Based Composites
Published 2025-01-01“…Mycelium-based composites (MBCs) are highly valued for their ability to transform low-value organic materials into sustainable building materials, offering significant potential for decarbonizing the construction sector. …”
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23700
60th Anniversary of Postgraduate School of Federal State-Financed Institution “Federal Centre for Animal Health”
Published 2021-08-01“…When the All-Union Foot-and-Mouth Disease Research Institute was founded in 1958, an active search for relevant specialists and researchers was organized with a view to recruiting them as staff members. …”
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