Granulomatosis with Polyangiitis in Adolescence: Two Distinct Presentations by Rafael Figueiredo, Inês Pires Duro, António Marinho, Conceição Mota, Margarida Guedes, Carla Zilhão

“…Pediatric patients have similar clinical manifestations to adults but different frequencies of organ involvement; constitutional symptoms are also more common. …”
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Altitudinal patterns of bacterial communities across soil layers in the alpine meadows of the Qinghai-Tibet Plateau by Zhiyuan Chen, Yeteng Xu, Xinyue Wang, Tong Ma, Yang Liu, Xiang Qin, Wei Zhang, Tuo Chen, Guangxiu Liu, Binglin Zhang

“…Conversely, alterations in surface soil bacterial community composition were more strongly correlated with total organic carbon (TOC).These findings elucidate distinct altitudinal patterns in bacterial community diversity and assembly between soil layers. …”
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To Hemoadsorb or Not to Hemoadsorb—Do We Have the Answer Yet? An Updated Meta-Analysis on the Use of CytoSorb in Sepsis and Septic Shock by Carmen Orban, Angelica Bratu, Mihaela Agapie, Tudor Borjog, Mugurel Jafal, Romina-Marina Sima, Oana Clementina Dumitrașcu, Mihai Popescu

“…Severe inflammation leading to organ dysfunction is the cornerstone of the pathophysiology of sepsis. …”
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Ecotoxicity of lanthanides to Daphnia magna: insights from elemental behavior and speciation in a standardized test medium by Vignati, Davide A.L., Martin, Loïc A., Poirier, Laurence, Zalouk-Vergnoux, Aurore, Fouque, Chantal, Bojic, Clément, Hissler, Christophe, Cossu-Leguille, Carole

“…This and other caveats must be considered in future research to reach a community-based consensus for the proper hazard and risk assessment of LN towards daphnids and other aquatic organisms.…”
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Fieldwork on animals living in extreme conditions as a source of biomedical innovation by Yvon Le Maho, Aurélie Tasiemski, Fabrice Bertile, Philippe Bulet

“…Most biomedical research on animals is based on the handful of the so-called standard model organisms, i.e. laboratory mice, rats or Drosophila, but the keys to some important biomedical questions may simply not be found in these. …”
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High-Affinity Anti-VISTA Antibody Protects against Sepsis by Inhibition of T Lymphocyte Apoptosis and Suppression of the Inflammatory Response by Tianzhu Tao, Lulong Bo, Teng Li, Longbao Shi, Hui Zhang, Bo Ye, Yuhai Xu, Qingqing Ma, Xiaoming Deng, Guorong Zhang

“…The effects of anti-VISTA mAb on the 7-day survival, lymphocyte apoptosis, cytokine expression, bacterial burden, and vital organ damage were determined. Furthermore, the effects of anti-VISTA mAb on CD3+ T cell apoptosis and macrophage activation were determined in vitro. …”
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Issues of diagnostics and treatment of abdominal pain at irritable bowel syndrome at outpatient stage of the healthcare by Yu. A. Kucheryavy, T. L. Lapina, M. A. Livzan, M. F. Osipenko

“…Implementation of diagnostic algorithm allows to distinguish the organic disease or to establishthe diagnosis of functional disease. …”
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Deep-Learning-Driven Insights into Nitrogen Leaching for Sustainable Land Use and Agricultural Practices by Caixia Hu, Jie Li, Yaxu Pang, Lan Luo, Fang Liu, Wenhao Wu, Yan Xu, Houyu Li, Bingcang Tan, Guilong Zhang

“…Analyses of the feature importance and SHAP values in the optimal XGBoost model identified soil organic matter, chemical nitrogen fertilizer input, and water input (including rainfall and irrigation) as the main indicators of nitrate leaching loss. …”
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Indirect electrochemical detection of perfluoro decanoic acid from water by Sorina-Claudia Negrea, Lidia Ani Diaconu, Dorian Neidoni, Adina Pacala, Luoana Florentina Pascu, Sorina Motoc, Anamaria Baciu, Elena Trif, Florica Manea

“…This method holds promise for advancing detection techniques for persistent organic pollutants in environmental and public health contexts.…”
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Gastrointestinal lesions of eosinophilic granulomatosis with polyangiitis: a prediction model and clinical patterns by Suying Liu, Yunjiao Yang, Linna Han, Chengmei He, Mengtao Li, Xinping Tian, Juan Meng, Li Wang, Fengchun Zhang

“…The correlation between different organ lesions was calculated to explore the clinical patterns. …”
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Cognitive impairment and self-reported health outcomes among older adults: Longitudinal evidence from Australia by Rezwanul Haque, Khorshed Alam, Jeff Gow, Christine Neville, Syed Afroz Keramat

“…To enhance the physical and mental health and well-being of older adults, the community, government and non-government organizations, and other stakeholders should prioritize routine healthcare prevention, targeted interventions, and treatment practices, particularly for individuals with or at risk of cognitive impairment.…”
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Expression Analysis and Functional Validation of DcTPSb1 in Terpene Synthesis of <i>Dendrobium chrysotoxum</i> by Yuxuan Jin, Shuting Zhou, Zhihui Du, Weize Wang, Zhilin Chen

“…<i>DcTPSb1</i> exhibited elevated expression levels in flowers among four organs (roots, stems, leaves, flowers) of <i>D. chrysotoxum</i>, with the highest expression observed during the blooming phase, which aligned with the accumulation of volatile terpenes during flowering. …”
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Solid Sr2Ti1-xMnxO4 (x = 0; 0,01; 0,025; 0,05; 0,1) solutions with K2NiF4 structure by T.I. Chupakhina, A.M. Uporova, O.I. Gyrdashova, L.Yu. Buldakova, Y.A. Deeva, I.V. Baklanova, M.Yu. Yanchenko

“…The products of thermolysis of the obtained complexes with an organic ligand are isostructural single-phase samples, which crystallize as agglomerates with an average size of 1 μm. …”
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Extrinsic attributes that drive consumer purchase of block mozzarella by K. Homwongpanich, M.E. Watson, D. Rovai, H. Eshpari, M.A. Drake

“…Consumer segmentation identified a natural cluster (n = 243) which assigned high utility to claims such as “all natural” and “organic” while the flavor cluster (n = 194) assigned high utility to “established business for more than 75 years” and “#1 in Italy.” …”
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Differential Regulation of Methylation-Regulating Enzymes by Senescent Stromal Cells Drives Colorectal Cancer Cell Response to DNA-Demethylating Epi-Drugs by Khushboo Agrawal, Viswanath Das, Natálie Táborská, Ján Gurský, Petr Džubák, Marián Hajdúch

“…The advanced-stage colon cancer spreads from primary tumor site to distant organs where the colon-unassociated stromal population provides a favorable niche for the growth of tumor cells. …”
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Optimization of Silkworm Pupae Fermentation by Response Surface Methodology and Products Taste Characteristics Study by Fangli QIN, Siyuan WANG, Yuxiao ZOU, Erna LI, Lixia MU, Qingrong LI

“…Compared with those in unfermented silkworm pupae, the free amino acid, nucleotide, and organic acid contents in fermented silkworm pupae were significantly increased (P<0.05), reaching 52.19±0.11, 1.01±0.03, and 65.54±1.61 mg/g, respectively. …”
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Nomenclatural issues concerning cultured yeasts and other fungi: why it is important to avoid unneeded name changes by Andrey Yurkov, Artur Alves, Feng-Yan Bai, Kyria Boundy-Mills, Pietro Buzzini, Neža Čadež, Gianluigi Cardinali, Serge Casaregola, Vishnu Chaturvedi, Valérie Collin, Jack W. Fell, Victoria Girard, Marizeth Groenewald, Ferry Hagen, Chris Todd Hittinger, Aleksey V. Kachalkin, Markus Kostrzewa, Vassili Kouvelis, Diego Libkind, Xinzhan Liu, Thomas Maier, Wieland Meyer, Gábor Péter, Marcin Piątek, Vincent Robert, Carlos A. Rosa, Jose Paulo Sampaio, Matthias Sipiczki, Marc Stadler, Takashi Sugita, Junta Sugiyama, Hiroshi Takagi, Masako Takashima, Benedetta Turchetti, Qi-Ming Wang, Teun Boekhout

“…The unambiguous application of names is assured by the preservation of nomenclatural history and the physical organisms representing a name. Fungi are extremely diverse in terms of ecology, lifestyle, and methods of study. …”
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The Essential Role of Monte Carlo Simulations for Lung Dosimetry in Liver Radioembolization—Part B: ¹⁶⁶Ho Microspheres by Edoardo d’Andrea, Andrea Politano, Bartolomeo Cassano, Nico Lanconelli, Marta Cremonesi, Vincenzo Patera, Massimiliano Pacilio

“…Lung dosimetry was assessed for five lung shunt (LS) scenarios with conventional methods: the mono-compartmental organ-level approach (MIRD), voxel S-value convolution for soft tissue (kST, ICRU soft tissue with 1.04 g/cm³) and lung tissue (kLT, ICRU lung tissue with 0.296 g/cm³), local density rescaling (kST<i>_L</i> and kLT<i>_L</i>, respectively, for soft tissue and lung tissue), or global rescaling for a lung mean density of 0.221 g/cm³ (kLT₂₂₁). …”
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Standardization in the management of gram-negative bloodstream infections after implementation of a clinical care guideline at a large academic, safety-net institution: a quasi-exp... by Michael A. Deaney, Katherine C. Shihadeh, Alexandra Craig, Margaret M. Cooper, Paul D. Paratore, Timothy C. Jenkins

“…Participants: Adults (≥18 years) with GN-BSI, defined by at least one positive blood culture for specific gram-negative organisms. Patients with polymicrobial cultures or contaminants were excluded. …”
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ZEB1 as a marker of metastasis in thyroid carcinomas: review of literature and own data by P.P. Zinych, V.M. Pushkarev, N.I. Levchuk, M. Tronko

“…The metastatic process involves the exit of cancer cells from the primary tumor into the blood or other transport system, colonization and proliferation in a distant organ. The key process of the metastatic cascade is the epithelial-mesenchymal transition (EMT), which consists in the transformation of epithelial cells into mesenchymal, capable for migration. …”
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