Smoking as a causative factor in chronic kidney disease: a two-sample Mendelian randomization study by Yue Yang, Zheng Zhang, Hai-tao Lu, Qian-qian Xu, Li Zhuo, Wen-ge Li

“…Smoking is widely acknowledged for its harmful effects on multiple organs. However, its specific causal relationship with chronic kidney disease (CKD) remains uncertain. …”
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Volumetric trans-scale imaging of massive quantity of heterogeneous cell populations in centimeter-wide tissue and embryo by Taro Ichimura, Taishi Kakizuka, Yoshitsugu Taniguchi, Satoshi Ejima, Yuki Sato, Keiko Itano, Kaoru Seiriki, Hitoshi Hashimoto, Ko Sugawara, Hiroya Itoga, Shuichi Onami, Takeharu Nagai

“…Our results demonstrate the potential of this technique in accelerating production of comprehensive reference maps of all cells in organisms and tissues, which contributes to understanding developmental processes, brain functions, and pathogenesis of disease, as well as high-throughput quality check of tissues used for transplantation medicine.…”
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CDK14 regulates the development and repair of lung by Jian-wei Chen, Yu-xiang Wang, Rong-rong Gao, Lan-yue Ma, Jing Zhong, Jia-xin Yang, Zhao-hua Deng, Yu-yan Li, Xiao-ling Li, Ya-hai Shu, Wen-jing Guo, Zi-yuan Zhou, Xiao Yu Tian, Jinjin Ma, Yang Liu, Qi Chen

“…However, the function of CDK14 during organ development and regeneration has not been investigated in genetically-modified animals. …”
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Quantitative descriptive analysis, non-targeted metabolomics and molecular docking reveal the dynamic aging and taste formation mechanism in raw Pu-erh tea during the storage by Bingsong Ma, Cunqiang Ma, Binxing Zhou, Xuan Chen, Yuhua Wang, Yifan Li, Junfeng Yin, Xinghui Li

“…Notable changes included the reduction, transformation, and condensation of flavonoids (such as catechins, flavonol glycosides, and anthocyanins) and amino acids, alongside an accumulation of organic acids, catechin/amino acid derivatives, flavoalkaloids, and gallic acid. …”
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Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target by Cèlia Dobaño-López, Juan García Valero, Ferran Araujo-Ayala, Ferran Nadeu, Fabien Gava, Carla Faria, Marine Norlund, Renaud Morin, Pascale Bernes-Lasserre, Fabian Arenas, Marta Grau, Cristina López, Irene López-Oreja, Neus Serrat, Ares Martínez-Farran, Lluís Hernández, Heribert Playa-Albinyana, Rubén Giménez, Silvia Beà, Elías Campo, Jean-Michel Lagarde, Armando López-Guillermo, Laura Magnano, Dolors Colomer, Christine Bezombes, Patricia Pérez-Galán

“…Here we present the first FL-Patient Derived Lymphoma Spheroid (FL-PDLS), including fundamental immune actors and features of TME in FL lymph nodes (LNs). FL-PDLS is organized in disc-shaped 3D structures composed of proliferating B and T cells, together with macrophages with an intermediate M1/M2 phenotype. …”
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A Study of the Corrosion Behavior of AHSS Complex-Phase CP 780 Employing an Electrochemical Noise Technique Analyzed by Different Methods by Maria Lara-Banda, Facundo Almeraya-Calderón, Jesús Manuel Jáquez-Muñoz, Demetrio Nieves-Mendoza, Miguel Angel Baltazar-Zamora, Javier Olguín-Coca, Francisco Estupiñan-Lopez, Jose Cabral Miramontes, Griselda Santiago-Hurtado, Citlalli Gaona-Tiburcio

“…The main point of this research is to characterize an AHSS complex-phase (CP) 780 in blank, with a phosphate coating and an E-coat organic coating using electrochemical noise, employing time-domain, frequency-domain, time–frequency-domain, and chaotic system methods to determine the type and corrosion kinetics of each system. …”
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The triterpenoids-enriched extracts from Antrodia cinnamomea mycelia attenuate alcohol-induced chronic liver injury via suppression lipid accumulation in C57BL/6 mice by Yange Liu, Ronglong Chen, Lanzhou Li, Ruitao Dong, Hui Yin, Yawen Wang, Anhui Yang, Jianbin Wang, Changtian Li, Di Wang

“…In long-term alcohol consumption mice, the significantly lost body weight, increased organ indexes, hepatic alanine aminotransferase and aspartate aminotransferase levels were all remissed after 6-week ACT orally administration, showing its hepatoprotective property. …”
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Bacterioplankton Activity in a Meso-eutrophic Subtropical Coastal Lagoon by Maria L. Schmitz Fontes, Heloísa Fernandes, Manoela Brandão, Mariana Coutinho Hennemann, Raquel Aparecida Loss, Valdelúcia Maria Alves de Souza Grinevicius, Denise Tonetta, Karina Cesca, Mônica Hessel Silveira, Mara Bedin, Derce Recouvreux, Regina Vasconcellos Antônio

“…The aim of this study was to investigate whether the bacterioplankton activity in the meso-eutrophic Conceição Lagoon would increase significantly under allochthonous inputs of inorganic nutrients and organic carbon. Abundance and biomass of bacterioplankton were evaluated under three treatments: light (14 h light/10 h dark), complete darkness (dark-control), and nutrient (C + N + P—dark, 100 : 10 : 1) enrichments during 72 h. …”
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Role of Inflammation and Motility Disorders in the Development, Course and Consequences of Functional Gastrointestinal and Biliary Tract Diseases (Literature Review and Expert Pane... by V. T. Ivashkin, D. S. Bordin, T. L. Lapina, M. A. Livzan, A. V. Okhlobystin, E. A. Poluektova, A. S. Trukhmanov, Yu. P. Uspenskiy, Yu. O. Shulpekova

“…Functional diseases are believed to modify the symptoms and course of concomitant organic diseases of the gastrointestinal tract (for example, functional diseases of the biliary tract may contribute to the development of cholelithiasis, pancreatitis). …”
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Grazing reduces shrub-facilitated diversity of ground-dwelling arthropods in semiarid ecosystems by Jiancai Sun, Rentao Liu, Marcelo Sternberg, Lei Zhou, Zhimin Yang

“…The key drivers of herbaceous plant height in ungrazed plots and those of soil bulk density, soil organic carbon, and soil moisture in grazed plots shaped ground-dwelling arthropod distribution between microhabitats. …”
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OCF Bridging Techniques for UWB/LoRa IoT Ecosystems by Hyun Seob Oh, Wha Sook Jeon, Dong Geun Jeong

“…The Open Connectivity Foundation (OCF) is one of the most powerful IoT standard organizations. The OCF has developed not only its own standard but also an open source software framework called IoTivity for efficient implementation of IoT systems. …”
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Pharmacokinetics of Transdermal Flunixin Meglumine Following a Single Dose in Marine Toads (Rhinella marina) by Gregory Scott, Meghan M. Louis, Julie A. Balko, Claire M. Bublitz, Brigid V. Troan, Ronald E. Baynes, Dustin Smith, Larry J. Minter

“…Histopathology of skin and major organs revealed one minimal superficial lesion in a single toad potentially attributable to flunixin meglumine administration; otherwise, no other treatment-related lesions were observed in 11 of 12 toads. …”
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The Impact of Nurses' Disaster Preparedness Competencies on Public Health Center Resilience in Disaster-Prone Areas: A cross-sectional study by Moh Ikram Dg Sirua, Balqis Balqis, Muhammad Alwy Arifin, Indar Indar, Syamsuar Manyullei

“…Conclusion: This study highlights the importance of strengthening these competencies and fostering collaboration with local governments, health institutions, communities, and non-governmental organizations (NGOs) to support comprehensive disaster preparedness efforts. …”
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The impact of abandoned iron ore on the endophytic bacterial communities and functions in the root systems of three major crops in the local area by Shuyi Chen, Jie Tang, Junqiang Xu, Lianxin Peng, Peng Wu, Qiang Li

“…., and Triticum aestivum L. were collected from the inter-root soils and plant roots to determine the soil physicochemical properties and endophytic bacterial communities in the root system.ResultsThe results showed that mining resulted in soil acidification, altered trace element content and increased organic carbon. There was an increase in the Ascomycota and Actinobacteria phylum of crop root bacteria. …”
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Use of Hybrid Flame Retardants in Chemically Foamed rPET Blends by Veronika Anna Szabó, Sándor Kálmán Jakab, András Kovács, Tamara Zsuzsanna Böcz, Gábor Dogossy

“…Three different kinds of halogen-free flame retardant agents were used: ammonium polyphosphate-based Exolit AP 422 (AP), organic aluminum phosphate in the form of Exolit OP 1240 (OP), and Budit 342 containing melamine polyphosphate (MPP). …”
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Bedrock modulates the elevational patterns of soil microbial communities by Xianjin He, Ruiqi Wang, Daniel S. Goll, Laurent Augusto, Naoise Nunan, M.D. Farnon Ellwood, Quanzhou Gao, Junlong Huang, Shenhua Qian, Yonghua Zhang, Zufei Shu, Buhang Li, Chengjin Chu

“…Bedrock and elevation strongly influenced microbial beta-diversity, with beta-diversity on granite driven primarily by soil total phosphorus and moisture, and on slate by soil organic carbon and pH. In contrast, alpha-diversity was impacted less by bedrock and elevation, but its relationship with environmental factors varied markedly between bedrock types. …”
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Multi-step pre-treatment of rice husk for fractionation of components including silica by Shinnosuke Ishida, Shinji Kudo, Shinji Kudo, Shusaku Asano, Shusaku Asano, Jun-ichiro Hayashi, Jun-ichiro Hayashi

“…IntroductionRice husk, a widely available agricultural by-product lignocellulosic biomass, is a promising and sustainable feedstock for organic and inorganic chemicals due to the rich silica content. …”
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Within-species variation in the gut microbiome of medaka (Oryzias latipes) is driven by the interaction of light intensity and genetic background by Evangelista, Charlotte, Kamenova, Stefaniya, Diaz Pauli, Beatriz, Sandkjenn, Joakim, Vøllestad, Leif Asbjørn, Edeline, Eric, Trosvik, Pål, de Muinck, Eric Jacques

“…Given the growing evidence about the gut microbiomes importance to host health, more in-depth studies are required to fully understand the role of the microbiome in size-selected organisms and the possible ecosystem-level consequences. …”
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Toward a Next Generation Particle Precipitation Model: Mesoscale Prediction Through Machine Learning (a Case Study and Framework for Progress) by Ryan M. McGranaghan, Jack Ziegler, Téo Bloch, Spencer Hatch, Enrico Camporeale, Kristina Lynch, Mathew Owens, Jesper Gjerloev, Binzheng Zhang, Susan Skone

“…With a more capable representation of the organizing parameters and the target electron energy flux observations, PrecipNet achieves a >50% reduction in errors from a current state‐of‐the‐art model oval variation, assessment, tracking, intensity, and online nowcasting (OVATION Prime), better captures the dynamic changes of the auroral flux, and provides evidence that it can capably reconstruct mesoscale phenomena. …”
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An atypical case of infective endocarditis initially diagnosed as myopericarditis by Negin Ceraolo, Rachel Dietz, Spencer Prete, Erin L Simon

“…Diagnosis relies on clinical evaluation, blood cultures to identify the causative organism, and echocardiography to visualize vegetations on heart valves. …”
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