Biomimetic Targeted Co‐Delivery System Engineered from Genomic Insights for Precision Treatment of Osteosarcoma by Tianqi Luo, Zhijin Fan, Anyu Zeng, Anqi Wang, Yuanwei Pan, Yanyang Xu, Hongmin Chen, Weiqing Chen, Dingmeng Nie, Jiaming Lin, Anfei Huang, Ming Gong, Yufeng Huang, Yun Ding, Xiaojun Zhu, Lang Rao, Jin Wang

“…Based on these findings, a co‐delivery system loaded with CDK4/6 inhibitors and poly ADP‐ribose polymerase (PARP) inhibitors is designed. By employing metal–organic frameworks (MOFs) as carriers, issue of drug insolubility is effectively addressed, while also enabling controlled release in response to the tumor microenvironment. …”
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Sex-Differences in Renal Expression of Selected Transporters and Transcription Factors in Lean and Obese Zucker Spontaneously Hypertensive Fatty Rats by Andrea Babelova, Birgitta C. Burckhardt, Waja Wegner, Gerhard Burckhardt, Maja Henjakovic

“…The aim of this study was to identify sex-dependent expression of renal transporter mRNA in lean and obese Zucker spontaneously hypertensive fatty (ZSF1) rats and to investigate the interaction of the most altered transporter, organic anion transporter 2 (Oat2), with diabetes-relevant metabolites and drugs. …”
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Development and validation of the Iranian Social Health Questionnaire (IrSHQ) by Hassan Rafiey, Mostafa Amini Rarani, Fardin Alipour, Esmaeil Khedmati Morasae

“…Results: We developed the Iranian Social Health Questionnaire (IrSHQ) consisting of a 29-item questionnaire organized in seven subscales – ‘Social interaction’, ‘social responsibility’, ‘conscientiousness’, ‘attitude to society’, ‘empathy’, ‘family relationship’, and ‘social participation’−. …”
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Effects of <i>Lactiplantibacillus plantarum</i> on Metabolites and Flavors in Synthetic Microbiota During Baijiu Fermentation by Chunyue Yan, Xurui Chen, Quan Liu, Tengyu Xu, Qian Zhang, Xueli Jin, Bei Liao, Xiong Chen, Xin Li

“…The addition of <i>L. plantarum</i> also significantly increased the concentration of total organic acids, particularly lactic acid, which rose by 17 to 123 times. …”
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The Impact of Physical Activities on Male Fertility: A Systematic Review by Albert Kapla, Alicja Černohorská, Daria Bednarczyk, Julia Białeta, Karolina Siembab, Katarzyna Rowińska, Michalina Jurkiewicz, Wiktor Garbarczyk, Wiktoria Pysiewicz, Agnieszka Napieralska

“…Another issue discussed is the negative impact of exercise on fertility, as well as injuries in the perineal region—some of which directly affect organs, surrounding tissues (such as nerves), and regulatory mechanisms like hypothalamic-pituitary-gonadal axis. …”
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Evaluating the Effectiveness of Zero Trust Architecture in Protecting Against Advanced Persistent Threats by Pushpendra Kumar Verma, Bharat Singh, Preety, Shubham Kumar Sharma, Rakesh Prasad Joshi

“…By offering a thorough evaluation framework and useful suggestions for effective implementation, it is helpful to organizations looking to adopt Zero Trust Architecture. …”
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Probing aspects of extracellular vesicle associated AAV allows increased vector yield and insight into its transduction and immune-evasive properties by Ming Cheng, Demitri de la Cruz, Adam V. Crain, Paula Espinoza, Carrie Ng, Zachary C. Elmore, Aravind Asokan, Casey A. Maguire

“…EV-AAV provides desirable gene delivery traits such as greater resistance to antibody neutralization and increased transduction of organs in vivo compared with conventional AAV. Despite these promising data, better characterization of EV-AAV is needed. …”
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The regulation of tobacco growth under preceding crop planting: insights from soil quality, microbial communities, and metabolic profiling by Peiyan Zhao, Houfa Zhou, Xiaolin Liao, Leifeng Zhao, Yuanxian Zheng, Tiane Xiong, Gaorun Zhang, Sirong Jiang, Jiming Wang, Yuansheng He, Jiangtao Li, Jieying Zhu, Yongjun Zhang, Yanrun Li, Fuzhao Nian, Di Liu

“…Metabolomics analysis showed that different preceding crops altered lipids, organic acids, flavonoids, alkaloids, and terpenoids, enhancing secondary metabolite synthesis pathways in soil. …”
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Effect of Temperature on Synthesis of Hydroxyapatite/Chitosan Composite Using the <i>In-Situ</i> Method as a Heavy Metal Adsorbent by Novesar Jamarun, Tri Yupi Amirullah, Syukri Syukri, Arika Prasejati, Wulandari Wulandari, Sintia Caniago, Nabiila Ayyu Tricahyani

“…Removing hazardous non-organic waste containing heavy metals like copper and lead is crucial for environmental protection. …”
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Harnessing the Power of Citizen Science for Agroecological Transitions: The Case of the One Million Voices of Agroecology Initiative and Digital Platform by Lisa Elena Fuchs, Lily Cannell van Dien, Maria Rosa ‘Rosy’ Mondardini, Ma Estrella ‘Esther’ Penunia, Irish Baguilat, Sergio Iván Larrea Macías, Marcelo Soares Souza, Eduardo Fernandes Formighieri, Murilo Gelain Gonçalves, Rodrigo B. Westphalen, Vitória Pimentel, Fabio Ricci, Daria Levina, Matthias Geck

“…Its goal was to co-develop a citizen science platform that enables farmers, producer organizations, and consumers around the world to participate in agroecology movements, support agroecology adoption, and contribute to the co-creation and sharing of knowledge on the performance of agroecology. …”
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Effect of microencapsulated Fiber2-displaying probiotics loaded with inulin nanoparticles on immunity against fowl adenovirus serotype 4 in chickens by Biao Wang, Meiyuan Tian, Yashu Yang, Zhipeng Jia, Faisal R Anjum, Chunli Ma, Dexing Ma

“…Animal experiments demonstrated that oral immunization with Micro-E/Fiber2-PINs significantly enhanced humoral and cellular immune responses, relieved inflammatory injury in FAdV-targeted organs, and improved survival rate of challenged chickens. …”
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4-Nitroaniline Degradation by TiO2 Catalyst Doping with Manganese by Kai Zheng, Tong-chao Zhang, Pin Lin, Yu-hua Han, Hong-yi Li, Ren-jie Ji, Hai-yun Zhang

“…The performance of degradation of 4-nitroaniline was evaluated by analyzing cracking ratio of 4-nitroaniline ring, the chemical oxygen demand (COD), and total organic carbon (TOC) in remaining solution. Monitored parameters during all the photocatalytic reaction including dissolved oxygen, direct voltage, and radiation dosage of ultraviolet rays were investigated. …”
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Radiation Induces Pulmonary Fibrosis by Promoting the Fibrogenic Differentiation of Alveolar Stem Cells by Lu-Kai Wang, Tsai-Jung Wu, Ji-Hong Hong, Fang-Hsin Chen, John Yu, Chun-Chieh Wang

“…The lung is a radiosensitive organ, which imposes limits on the therapeutic dose in thoracic radiotherapy. …”
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Determination of Pendimethalin Dynamic Residual Distribution in Crucian Carp Tissues and Associated Risk Assessment by Lu Qiao, Na Yuan, Gang Han, Bo Cheng, Defu Zhang, Jinlong Song, Yingchun Mu

“…Pendimethalin has been considered a moderately to extremely toxic compound for fish and aquatic organism. This study developed the determination of dynamic residual distribution for pendimethalin in crucian carp tissues (muscle, liver, kidney, gill, and blood) under semistatic exposure system by high-performance liquid chromatography-tandem mass spectrometry (HPLC-MS/MS) method. …”
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Transcriptome response in a marine copepod under multigenerational exposure to ocean warming and Ni at an environmentally realistic concentration by Yunlei Zhang, Shiru Lin, Yaolu Niu, Xiaoping Zhou, Qingxian Lin

“…Currently, studies have concerned the combined effects of Ni and warming in marine organisms at the phenotypic level; however, the underlying molecular mechanisms are poorly known. …”
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Association between the exposure to brominated flame retardants and psoriasis risk among U.S. adults: A population-based study by Jingbo Zhang, Xiangyun Shi, Genlong Bai, Jin Chen, Yidian Fu, Aijun Chen

“…Because BFRs are extensively used and detected in various environmental sources and living organisms, future investigations should further elucidate the mechanisms underlying the observed associations between BFRs exposure and psoriasis risk.…”
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Linking Endotoxins, African Dust PM10 and Asthma in an Urban and Rural Environment of Puerto Rico by Mario G. Ortiz-Martínez, Rosa I. Rodríguez-Cotto, Mónica A. Ortiz-Rivera, Cedric W. Pluguez-Turull, Braulio D. Jiménez-Vélez

“…The objective of the study was to evaluate the toxicological and proinflammatory responses stimulated by ADE PM10 ENX reaching PR using human bronchial epithelial cells. PM10 organic extracts from a rural and urban site in PR (March 2004) were obtained from ADE and non-ADE and compared. …”
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Determination of the copy numbers of type A porcine endogenous retroviruses in domestic pigs and wild boars by R. B. Aitnazarov, N. S. Yudin, R. S. Kiril’chuk, N. N. Kochnev, S. P. Knyazev, M. I. Voevoda

“…To solve this problem, the use of animal organs and tissues for grafting to humans (xenografts) has been proposed. …”
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Selective ATP-Binding Cassette Subfamily C Gene Expression and Proinflammatory Mediators Released by BEAS-2B after PM2.5, Budesonide, and Cotreated Exposures by Jarline Encarnación-Medina, Rosa I. Rodríguez-Cotto, Joseph Bloom-Oquendo, Mario G. Ortiz-Martínez, Jorge Duconge, Braulio Jiménez-Vélez

“…This study assesses ABCC1–4 gene expression changes and proinflammatory cytokine (IL-6, IL-8) release in human bronchial epithelial cells (BEAS-2B) exposed to PM2.5 organic extract, budesonide (BUD, used to control inflammation in asthmatic patients), and a cotreatment (Co-T: PM2.5 and BUD). …”
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Customizing the optical, electronic and transport attributes of lead-free hybrid FASnBr3 perovskites triggered by spin-orbit coupling and strains by Nusrat Jahan, Farah B.H. Pritu, Md Rasidul Islam, Budrun Neher, M Mahbubur Rahman, Farid Ahmed

“…Organic-inorganic hybrid halide perovskites are emerging as promising materials for solar energy due to their unique structures and electronic properties. …”
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