Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells by Ying Yin, Liquan Zhou, Shuiqiao Yuan

“…Some other retrotransposons reside in the vicinity of endogenous genes and are capable of regulating nearby genes and cell fate, possibly through providing alternative promoters, regulatory modules, or orchestrating high-order chromatin assembly. In addition, retrotransposons may mediate epigenetic memory, regulate gene expression posttranscriptionally, defend virus infection, and so on. …”
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INTERROGATING THE EFFECTS OF ARMED BANDITRY ON THE SOCIO-ECONOMIC DEVELOPMENT OF NIGERIA’S NORTH-CENTRAL REGION (2015-2022) by YUSUFU Ahmed Audu, ODAUDU Alfred Idachaba, ILEVBARE Igheoise Trust

“… Armed banditry has being a major security challenge confronting northern Nigeria in recent years. Attacks orchestrated by these armed bandits have continued to escalate, especially since 2015 when the Buhari administration came into power with attendant consequences of loss of human lives, destruction of property, displacement of persons, loss of livelihoods and disruption of socio-economic activities. …”
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The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review by Wenhao Wu, Guoqiang Fan

“…Small RNAs (miRNAs) and long non-coding RNAs (lncRNAs) act as post-transcriptional regulators, orchestrating immune signaling and pathogen counter-defense strategies. …”
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Pluripotency Factors on Their Lineage Move by Clair E. Weidgang, Thomas Seufferlein, Alexander Kleger, Martin Mueller

“…However, detailed underlying insights into how these transcription factors orchestrate cell fate decisions remain largely elusive. …”
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RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA by AUSTEEN NDUBUISI ADIGWE

“…The implications of this in the long run remains unpredictable but the effect of this in contemporary times is orchestrating outcomes that offers no heritage of good to all and sundry. …”
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A Decade of FGF Receptor Research in Bladder Cancer: Past, Present, and Future Challenges by Erica di Martino, Darren C. Tomlinson, Margaret A. Knowles

“…Fibroblast growth factors (FGFs) orchestrate a variety of cellular functions by binding to their transmembrane tyrosine-kinase receptors (FGFRs) and activating downstream signalling pathways, including RAS/MAPK, PLCγ1, PI3K, and STATs. …”
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Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome by Yu Han, Huaquan Wang, Zonghong Shao

“…Macrophages are innate immune cells that ingest and degrade abnormal cells, debris, and foreign material and orchestrate inflammatory processes. We analyzed the role of macrophages from MDS patients in vitro. …”
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Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells by Eun Jung Kwak, Young Soon Lee, Eun Mi Choi

“…Skeletal turnover is orchestrated by a complex network of regulatory factors. …”
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R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania by Jeziel D. Damasceno, Emma M. Briggs, Marija Krasilnikova, Catarina A. Marques, Craig Lapsley, Richard McCulloch

“…This work provides a link between R-loop homeostasis and DNA replication timing in a eukaryotic parasite and demonstrates that orchestration of DNA replication dictates levels of genome plasticity in Leishmania.…”
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Schwann cells in regeneration and cancer by Lan Zhang, Jiale Xie, Wenyu Dai, Bing Lu, Sheng Yi

“…Injury responses stimulate c-Jun activation in Schwann cells, drive epithelial-mesenchymal transition and cellular phenotypic changes, and induce the generation of reprogrammed repair Schwann cells to orchestrate peripheral nerve regeneration process. Schwann cells and/or Schwann cell-derived molecules are commonly used as supporting cells and/or neurotrophic factors to construct Schwann cell-based tissue-engineered nerve grafts for repairing severe peripheral nerve injury with long defects. …”
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Coactivators in PPAR-Regulated Gene Expression by Navin Viswakarma, Yuzhi Jia, Liang Bai, Aurore Vluggens, Jayme Borensztajn, Jianming Xu, Janardan K. Reddy

“…Upon ligand activation, PPARs undergo conformational changes that facilitate the dissociation of corepressor molecules and invoke a spatiotemporally orchestrated recruitment of transcription cofactors including coactivators and coactivator-associated proteins. …”
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Mechanisms and environmental factors shaping the ecosystem of brain macrophages by Silvia Penati, Simone Brioschi, Zhangying Cai, Claudia Z. Han, Claudia Z. Han, Marco Colonna, Marco Colonna

“…Several works have partially unveiled the mechanisms orchestrating the development of microglia and BAMs in both mice and humans; however, many questions remain unanswered. …”
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Piezo1-directed neutrophil extracellular traps regulate macrophage differentiation during influenza virus infection by Yuexin Wang, Qiuli Yang, Yingjie Dong, Likun Wang, Zhiyuan Zhang, Ruiying Niu, Yufei Wang, Yujing Bi, Guangwei Liu

“…In addition, Piezo1 integrates magnesium signalling and the SIRT2-hypoxia-inducible factor-1 alpha (HIF1α)-dependent pathway to orchestrate reciprocal M1 and M2 macrophage lineage commitment through neutrophil-derived NET DNA. …”
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Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The “Invisible Man” of Bacterial Vaginosis? by Thomas Bertran, Patrick Brachet, Marjolaine Vareille-Delarbre, Julie Falenta, Annie Dosgilbert, Marie-Paule Vasson, Christiane Forestier, Arlette Tridon, Bertrand Evrard

“…In the genital mucosa, dendritic cells (DCs) sense bacteria of the microenvironment via receptors and then orchestrate the immune response by induction of different T cell subtypes. …”
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The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking by Daniel P. Neumann, Katherine A. Pillman, B. Kate Dredge, Andrew G. Bert, Caroline A. Phillips, Rachael Lumb, Yesha Ramani, Cameron P. Bracken, Brett G. Hollier, Luke A. Selth, Traude H. Beilharz, Gregory J. Goodall, Philip A. Gregory

“…Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the extent of alternative polyadenylation (APA) during EMT has not yet been explored. …”
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Costimulatory Pathways: Physiology and Potential Therapeutic Manipulation in Systemic Lupus Erythematosus by Nien Yee Kow, Anselm Mak

“…Indeed, SLE is characterized by an orchestrated interplay amongst different types of immunopathologically important cells participating in both innate and adaptive immunity including the dendritic cells, macrophages, neutrophils and lymphocytes, as well as traditional nonimmune cells such as endothelial, epithelial, and renal tubular cells. …”
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Detection of Jihadism in Social Networks Using Big Data Techniques Supported by Graphs and Fuzzy Clustering by Cristina Sánchez-Rebollo, Cristina Puente, Rafael Palacios, Claudia Piriz, Juan P. Fuentes, Javier Jarauta

“…The research presented in this paper focuses on the analysis of Twitter messages to detect the leaders orchestrating terrorist networks and their followers. …”
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Extending OpenStack Monasca for Predictive Elasticity Control by Giacomo Lanciano, Filippo Galli, Tommaso Cucinotta, Davide Bacciu, Andrea Passarella

“…This paper introduces an architecture for predictive cloud operations, which enables orchestrators to apply time-series forecasting techniques to estimate the evolution of relevant metrics and take decisions based on the predicted state of the system. …”
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The Switchmaze: an open-design device for measuring motivation and drive switching in mice by Hartmann, Clara, Mahajan, Ambika, Borges, Vinicius, Razenberg, Lotte, Thönnes, Yves, Karnani, Mahesh Miikael

“…However, how the brain orchestrates switching between the neural mechanisms controlling motivated behaviours, or drives, is unknown. …”
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Myogenesis gone awry: the role of developmental pathways in rhabdomyosarcoma by Annika L. Gustafson, Annika L. Gustafson, Annika L. Gustafson, Adam D. Durbin, Kristin B. Artinger, Heide L. Ford, Heide L. Ford, Heide L. Ford

“…During normal myogenesis, these developmental transcription factors (TFs) orchestrate the formation of terminally differentiated, striated, and multinucleated skeletal muscle. …”
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