Deep mutational scanning of the Trypanosoma brucei developmental regulator RBP6 reveals an essential disordered region influenced by positive residues by Saúl Rojas-Sánchez, Nikolay G. Kolev, Christian Tschudi

“…RNA-binding protein 6 (RBP6) is a potent orchestrator of this process, however, an understanding of its functionally important domains and their mutational constraints is lacking. …”
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Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis by Amanda Sierra, Sol Beccari, Irune Diaz-Aparicio, Juan M. Encinas, Samuel Comeau, Marie-Ève Tremblay

“…Microglia cells are the major orchestrator of the brain inflammatory response. As such, they are traditionally studied in various contexts of trauma, injury, and disease, where they are well-known for regulating a wide range of physiological processes by their release of proinflammatory cytokines, reactive oxygen species, and trophic factors, among other crucial mediators. …”
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FGFR antagonists restore defective mandibular bone repair in a mouse model of osteochondrodysplasia by Anne Morice, Amélie de La Seiglière, Alexia Kany, Roman H. Khonsari, Morad Bensidhoum, Maria-Emilia Puig-Lombardi, Laurence Legeai Mallet

“…Taken as a whole, our findings show that FGFR3 is a critical orchestrator of bone repair and provide a rationale for the development of potential treatments for patients with FGFR3-osteochondrodysplasia.…”
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GEDUNG ORKESTRA DI MAKASSAR DENGAN PENDEKATAN ARSITEKTUR FUTURISTIK by Muhammad Ali Akbar, Marwati Marwati

“…Orchestral music could be a new color for the type of music that exist, especially in Makassar, so as to provide knowledge and understanding of orchestral music for the community and lovers of music, so the need for container for orchestral music performances and educational tool for the public in Makassar. …”
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LIGETI’S ROMANIAN CONCERTO: FROM WAX CYLINDERS TO SYMPHONY ORCHESTRA by Bianca ŢIPLEA TEMEŞ

“… Beneath the Romanian Concerto’s colourful orchestral surface, evoking the folk-inspired music of both Bartók and Enescu, lies Ligeti’s early activity as a researcher (1949-1950) at the Folklore Institute in Bucharest. …”
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Factors influencing the holding of Ilia Slatin’s Symphonic Concerts in Kharkiv in the 1870s–1880s by Lichuan Zhang

“…The article identifies the main factors that influenced this process: the organizational and financial conditions under which the musical society operated, as well as the orchestral performance practices of that time in Kharkiv. …”
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Research on the security of national secret algorithm based compute first networking by Jie PAN, Lan YE, Pengfei ZHANG, Zhonggui BU

“…With the promotion of national secret algorithm, in-depth research on the arithmetic network was carried out, a more efficient and reasonable security scheme for the arithmetic network was proposed, ensuring the data security and privacy of the arithmetic network with the help of the state secret algorithm.The main elements of the design program included: Supporting arithmetic demand and cryptographic invocation through the underlying resources, the arithmetic orchestration layer provided the ability to orchestrate data arithmetic, meanwhile, the arithmetic scheduling layer intelligently discerned the optimal nodes for arithmetic resource scheduling and allocation; the cryptographic reinforcement layer used the national secret algorithm based on hardware support with the help of public key cryptosystem, hash function, digital envelope, homomorphic encryption, blockchain and other technologies.Focusing on arithmetic network access security, transmission security, data security and privacy protection aspects of security implementation.An architecture and application form was innovatively proposed to guarantee the data security of the arithmetic network, which could meet the needs of the application layer arithmetic in the scenarios of big data, intelligent technology, etc..The security of the arithmetic network is enhanced by empowering the arithmetic network through the state-secret algorithm.…”
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An optimal defensive deception framework for the container‐based cloud with deep reinforcement learning by Huanruo Li, Yunfei Guo, Penghao Sun, Yawen Wang, Shumin Huo

“…The well‐trained DRL agent generates optimal placement strategies for the orchestration platform to distribute decoys and deceptive routings. …”
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Human T follicular helper cells and their impact on IgE and IgG4 production across allergy, malignancy, and IgG4-related disease by Mitsuhiro Akiyama, Waleed Alshehri, Sho Ishigaki, Koichi Saito, Yuko Kaneko

“…Human T follicular helper (Tfh) cells play a crucial role in orchestrating B cell differentiation, maturation, and immunoglobulin class switching. …”
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Five Open Problems on Designing 5G Network Architecture by Xiaodong Duan, Tao Sun, Wei Chen, Xiaoyong Han, Lu Lu

“…Motivated from requirement, five key questions were listed: centralization or distribution, access network and core network convergence, network orchestration, NFV& SDN impact to the architecture, evolution or revolution. …”
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THE RHYTHMICALLY, MELODICALLY AND RHYTHMIC-MELODICALLY ANALOGIES IN RICHARD WAGNER’S OPERAS by Gabriela Coca

“… In Richard Wagner’s opera the composer put the rhythm both in the service of the musical dramaturgy and also in the melody, the harmony, the polyphony, the orchestration and the musical form. The rhythmic and the melodic analogies of his musical works do not have this trait because of the lack of ideas of the composer. …”
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Dressed Up to the Nines: The Interplay of Phytohormones Signaling and Redox Metabolism During Plant Response to Drought by Douglas Jardim-Messeder, Ygor de Souza-Vieira, Gilberto Sachetto-Martins

“…Hormonal signaling and the maintenance of ROS homeostasis are interconnected, playing indispensable roles in growth, development, and stress responses and orchestrating diverse molecular responses during environmental adversities. …”
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Jardiner les décombres by Julie Scapino

“…Inspired by the permacultural model, these urban gardeners play with a nourishing nature in a space antinomic with life, by orchestrating a return to nature on the ruins of our industrial and artificialised society.…”
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Automata-Based Analysis of Stage Suspended Boom Systems by Anping He, Jinzhao Wu, Shihan Yang, Yongquan Zhou, Juan Wang

“…A stage suspended boom system is an automatic steeve system orchestrated by the PLC (programmable logic controller). …”
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Tom, volume e arranjo no chiaroscuro da memória: Sinfonia em branco, de Adriana Lisboa by Regina R. Félix

“…The characters’ memories, disconnected and repetitive, are orchestrated according those aesthetic patterns as an attempt to unravel the absurdity of their situation.…”
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Cloud native network for intelligent Internet of everything by Quan YU, Dandan LIANG, Wei ZHANG

“…A new cloud native network architecture for the future network architecture design in the era of intelligent Internet of everything was proposed, that is, network of the cloud, for the cloud, and by the cloud.Furthermore, the concept and mechanism of Cybertwin were proposed to tackle the challenges of mobility, security and availability in cloud native network.Three fundamental questions of cloud native network architecture design were also elaborated, that is, addressing, indexing and resource orchestration.Finally, 6G use cases and future research topics of Cybertwin based cloud native network were discussed.…”
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A Reconfigurable and Evolvable Platform for Network Function Innovation by Jianhui Zhang, Tong Duan, Xiaohui Zhang, Yuxiang Hu

“…To dealing with this problem, a reconfigurable and evolvable platform for network function innovation was proposed, which could adapt to the demand of network services by orchestrating functional modules in software plane. Then, configurable meta operation unit was used as data processing packet in hardware plane. …”
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WORLD DIABETES DAY 2023

“… On November 19, 2023, the Diabetes Association  of Pakistan (DAP) orchestrated a significant event  in Karachi, marking World Diabetes Day (WDD)  2023. …”
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Advancing civil infrastructure assessment through robotic fleets by Kay Smarsly, Kosmas Dragos

“…This short communication aims to portray a milestone in the field of monitoring and inspection of civil infrastructure, collaboratively conducted by autonomous, robotic devices orchestrated in robotic fleets. It is expected that robot-based civil infrastructure assessment will revolutionize structural maintenance of the deteriorating building stock, which is increasingly exacerbated by the effects of climate change and develops into a major societal challenge.…”
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Cutaneous Wound Healing: A Review about Innate Immune Response and Current Therapeutic Applications by Yara Adib, Armand Bensussan, Laurence Michel

“…This review will focus on innate cell populations involved in the initial phase of this orchestrated process, including innate cells from both the skin and the immune system.…”
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