Model Architecture Analysis and Implementation of TENET for Cell–Cell Interaction Network Reconstruction Using Spatial Transcriptomics Data by Ziyang Wang, Yujian Lee, Yongqi Xu, Peng Gao, Chuckel Yu, Jiaxing Chen

“…Cellular communication relies on the intricate interplay of signaling molecules, which come together to form the cell–cell interaction (CCI) network that orchestrates tissue behavior. Researchers have shown that shallow neural networks can effectively reconstruct the CCI from the abundant molecular data captured in spatial transcriptomics (ST). …”
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The role of immunity in insulin resistance in patients with polycystic ovary syndrome by Qixuan Zhang, Zhe Yang, Xiangyang Ou, Mengying Zhang, Xiangyu Qin, Gengxiang Wu

“…Therefore, this review aims to elucidate the interplay between IR in PCOS patients, the controlled immune response orchestrated by immune cells and immunomodulatory molecules, and their interactions with adipocytes, hyperandrogenemia, chronic inflammation, and metabolic homeostasis.…”
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The Golgi in Cell Migration: Regulation by Signal Transduction and Its Implications for Cancer Cell Metastasis by Valentina Millarte, Hesso Farhan

“…Uncovering the regulatory network that orchestrates cell migration is of fundamental importance for the development of new therapeutic strategies against cancer cell metastasis.…”
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Impaired Functional Connectivity in the Prefrontal Cortex: A Mechanism for Chronic Stress-Induced Neuropsychiatric Disorders by Ignacio Negrón-Oyarzo, Francisco Aboitiz, Pablo Fuentealba

“…Therefore, chronic stress may impair PFC functions required for the adaptive orchestration of behavioral responses. In the present review, we integrate evidence obtained from cognitive neuroscience with neurophysiological research with animal models, to put forward a hypothesis that addresses stress-induced behavioral dysfunctions observed in stress-related neuropsychiatric disorders. …”
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On the involvement of the second heart field in congenital heart defects by Guijarro, Clara, Kelly, Robert G.

“…SHF deployment creates the template for subsequent cardiac septation and has been implicated in cardiac looping and in orchestrating outflow tract development with neural crest cells. …”
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A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis by Rolf Müller, Martin Kömhoff, Jeffrey M. Peters, Sabine Müller-Brüsselbach

“…Recent evidence suggests that stromal PPARβ/δ regulates tumor endothelial cell proliferation and promotes differentiation leading to the properly orchestrated events required for tumor blood vessel formation. …”
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Dynamic Capabilities: A Measurement Proposal and its Relationship with Performance by Ivan Lapuente Garrido, Caroline Kretschmer, Silvio Luis de Vasconcellos, Cláudio Reis Gonçalo

“…There is a lack of empirical research that is attempting to investigate the existence, development, and orchestration of Dynamic Capabilities to support superior performance. …”
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Methodology for the Automatic Generation of Optimization Models of Systems of Flexible Energy Resources by Lukas Peter Wagner, Felix Gehlhoff, Lasse Matthias Reinpold, Georg Frey, Julian Jepsen, Alexander Fay

“…Typically, the operation of flexible energy resources is orchestrated through optimization models. However, the manual creation of these models is a complex and error-prone task, often requiring the expertise of domain specialists. …”
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Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis by Kar Neng Lai, Joseph C. K. Leung

“…Adipose tissue synthesizes different adipokines and cytokines that orchestrate and regulate inflammation, insulin action, and glucose metabolism locally and systemically. …”
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The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance by Nona Janikashvili, Bernard Bonnotte, Emmanuel Katsanis, Nicolas Larmonier

“…In turn, Treg that expand during tumor progression contribute to the immune tolerance of cancer by impeding DCs' ability to orchestrate immune responses and by directly inhibiting antitumoral T lymphocytes. …”
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BRICS 15 Years On: Challenges and Opportunities for Emerging Countries in the Shifting Global Institutional Landscape by Gabriel Rached, R.M. Rodrigues de Sá

“…Since 2009, BRICS nations have orchestrated collaborative economic strategies to recalibrate their positions on the global stage. …”
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Governmentality, Democracy, and Liberalism: Desire in Samrat Upadhyay’s ‘The Guru of Love’ by Pushpa Acharya

“…The novel itself, as a genre, becomes the canvas for orchestrating this transformative process, engaging both characters and readers. …”
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Locating the university lecture as a contemporary educational practice by Crook Charles

“…These are characterised in terms of three communication priorities: orchestration, enactment, and dialogue. An emphasis on the dialogic nature of exposition suggested an exploratory intervention in which students collaborated with a peer around a recorded lecture. …”
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Spatial transcriptomic analysis identifies epithelium-macrophage crosstalk in endometriotic lesions by Gregory W. Burns, Zhen Fu, Erin L. Vegter, Zachary B. Madaj, Erin Greaves, Idhaliz Flores, Asgerally T. Fazleabas

“…We propose that the superficial endometriotic lesion epithelium orchestrates inflammatory signaling and promotes a pro-repair phenotype in macrophages, providing a new role for complement 3 in lesion pathobiology. …”
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The Role of Plant DNA Methylation in Development, Stress Response, and Crop Breeding by Shuai Qiao, Wei Song, Wentao Hu, Fang Wang, Anzhong Liao, Wenfang Tan, Songtao Yang

“…The regulation of these methylation states relies on the coordinated actions of de novo methylation, maintenance, and active demethylation, orchestrated by specialized enzymes within distinct pathways. …”
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Calcium-mediated regulation of mitophagy: implications in neurodegenerative diseases by Fivos Borbolis, Christina Ploumi, Konstantinos Palikaras

“…Mitochondria, in particular, act as central hubs for calcium buffering, orchestrating energy production, redox balance and apoptotic signaling, among others. …”
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Radioresistance in rectal cancer: can nanoparticles turn the tide? by Diogo Coelho, Diogo Estêvão, Maria José Oliveira, Bruno Sarmento

“…Here, we revise the main molecular differences between rectal and colon tumors, exploring the complex orchestration beyond rectal cancer radioresistance and the most promising nanomedicines reported in the literature to improve neoadjuvant therapy response rates. …”
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Emerging Roles of Synapse Organizers in the Regulation of Critical Periods by Adema Ribic, Thomas Biederer

“…These processes have been extensively studied in the developing visual cortex, where critical period opening and closure are orchestrated by the assembly, maturation, and strengthening of distinct synapse types. …”
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The Pyramid and the Mosaic. Otto Neurath’s encyclopedism as a critical model by Andrea Alberto Dutto

“…Particularly, Neurath conceives of a comprehensive theory of a unified science that postulates the necessity of orchestration within the discursive procedures in science, inspired by the model of encyclopedism. …”
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Making Headway: The Roles of Hox Genes and Neural Crest Cells in Craniofacial Development by Paul A. Trainor

“…Craniofacial development is an extraordinarily complex process requiring the orchestrated integration of multiple specialized tissues such as the surface ectoderm, neural crest, mesoderm, and pharyngeal endoderm in order to generate the central and peripheral nervous systems, axial skeleton, musculature, and connective tissues of the head and face. …”
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