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301
PANoptosis in intestinal epithelium: its significance in inflammatory bowel disease and a potential novel therapeutic target for natural products
Published 2025-01-01“…Ample evidence has revealed substantial mechanistic convergence and intricate crosstalk among these three aforementioned forms of cell death, expanding the conceptualization of PANoptosis orchestrated by the PNAoptosome complex. This review provides a concise overview of the molecular mechanisms of apoptosis, necroptosis, and pyroptosis. …”
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302
Mutual Interests of Literary Criticism and Musical Criticism in the Field of Written Works A Case Study: "Music of Poetry" and "The Association of Poetry and Music"
Published 2017-12-01“…On the other hand, in recent decades, “Music of Poetry” concept with the formalist theme has suggested aesthetical criteria in studying and criticizing Persian poetry, and it has benefited from musical terms such as musicality, harmony, orchestration, etc. while musical critique has not presented any comment on written works of "music of poetry". …”
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303
Pluripotency Factors on Their Lineage Move
Published 2016-01-01“…However, detailed underlying insights into how these transcription factors orchestrate cell fate decisions remain largely elusive. …”
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304
Zum aktuellen Stand der professionellen Musikausbildung in Russland
Published 2021-12-01“…The focus is on a number of features in Russian music education: the continuity of three levels of education as a state system; training in conservatories not only for musicians, but also for musicologists; the large weight placed on the curriculum of disciplines aimed at fostering practical skills in counterpoint, harmonization, musical form analysis, orchestration, as well as methods of musical teaching, along with disciplines with an academic profile. …”
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305
RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA
Published 2024-12-01“…The implications of this in the long run remains unpredictable but the effect of this in contemporary times is orchestrating outcomes that offers no heritage of good to all and sundry. …”
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306
Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome
Published 2016-01-01“…Macrophages are innate immune cells that ingest and degrade abnormal cells, debris, and foreign material and orchestrate inflammatory processes. We analyzed the role of macrophages from MDS patients in vitro. …”
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307
Costimulatory Pathways: Physiology and Potential Therapeutic Manipulation in Systemic Lupus Erythematosus
Published 2013-01-01“…Indeed, SLE is characterized by an orchestrated interplay amongst different types of immunopathologically important cells participating in both innate and adaptive immunity including the dendritic cells, macrophages, neutrophils and lymphocytes, as well as traditional nonimmune cells such as endothelial, epithelial, and renal tubular cells. …”
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308
Detection of Jihadism in Social Networks Using Big Data Techniques Supported by Graphs and Fuzzy Clustering
Published 2019-01-01“…The research presented in this paper focuses on the analysis of Twitter messages to detect the leaders orchestrating terrorist networks and their followers. …”
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309
Extending OpenStack Monasca for Predictive Elasticity Control
Published 2024-06-01“…This paper introduces an architecture for predictive cloud operations, which enables orchestrators to apply time-series forecasting techniques to estimate the evolution of relevant metrics and take decisions based on the predicted state of the system. …”
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310
The Switchmaze: an open-design device for measuring motivation and drive switching in mice
Published 2024-04-01“…However, how the brain orchestrates switching between the neural mechanisms controlling motivated behaviours, or drives, is unknown. …”
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311
Myogenesis gone awry: the role of developmental pathways in rhabdomyosarcoma
Published 2025-01-01“…During normal myogenesis, these developmental transcription factors (TFs) orchestrate the formation of terminally differentiated, striated, and multinucleated skeletal muscle. …”
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312
Genome-Wide Identification and Expression Profiling of the <i>SPL</i> Transcription Factor Family in Response to Abiotic Stress in Centipedegrass
Published 2024-12-01“…SQUAMOSA promoter-binding protein-like (SPL) transcription factors play a critical role in the regulation of gene expression and are indispensable in orchestrating plant growth and development while also improving resistance to environmental stressors. …”
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313
Cancer-Associated Immune Resistance and Evasion of Immune Surveillance in Colorectal Cancer
Published 2016-01-01“…The development of cancer-specific “immune resistance” can be orchestrated either by cooperation with tumor microenvironment or by successive rounds of genetic/epigenetic changes. …”
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314
Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells
Published 2013-01-01“…These findings agree with the effect triggered by rSAA on matrix metalloproteinases (MMPs) activities measured in a gelatinolytic assay. rSAA inhibited activity of both MMPs in A172 cells while increasing them in T98G cells. rSAA also affected the production of compounds present in the tumor microenvironment that orchestrate tumor progression, such as IL-8, the production of reactive oxygen species (ROS) and nitric oxide (NO). …”
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315
Drosophila ubiquitin-specific peptidase 14 stabilizes the PERIOD protein by regulating a ubiquitin ligase SLIMB
Published 2025-02-01“…Abstract The circadian clock orchestrates behavior and physiology through the oscillation of key clock proteins like PERIOD (PER). …”
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316
Understanding Genetic Regulation of Sex Differentiation in Hermaphroditic Fish
Published 2025-01-01“…Furthermore, it examines the regulatory genes and associated signaling pathways that orchestrate sex determination and differentiation. By systematically synthesizing these research advancements, this paper endeavors to offer a comprehensive and profound insight into the intricate mechanisms governing sex differentiation in sequential hermaphroditic fish.…”
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317
Identification of Epinastine as CD96/PVR inhibitor for cancer immunotherapy
Published 2025-01-01“…Abstract Background Poliovirus receptor (PVR) and its receptor system, including TIGIT, CD226, and CD96, play a pivotal role in orchestrating tumor immune evasion. Upon engagement with PVR on tumor cells, CD96 exerts inhibitory effects on the function of T cells and NK cells, thereby fostering tumor immune evasion. …”
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318
T cell related osteoimmunology in fracture healing: Potential targets for augmenting bone regeneration
Published 2025-03-01“…Numerous immune cell types, including macrophages, T cells, and neutrophils are involved in fracture healing by orchestrating a series of events that modulate bone formation and remodeling. …”
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319
A Scalable Framework for Sensor Data Ingestion and Real-Time Processing in Cloud Manufacturing
Published 2025-01-01“…However, existing frameworks face challenges related to scalability, resource orchestration, and data security, particularly in rapidly evolving decentralized manufacturing settings. …”
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320
Systematic and comprehensive insights into HIF-1 stabilization under normoxic conditions: implications for cellular adaptation and therapeutic strategies in cancer
Published 2025-01-01“…Abstract Hypoxia-inducible factors (HIFs) are essential transcription factors that orchestrate cellular responses to oxygen deprivation. …”
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