Showing 281 - 300 results of 432 for search '"orchestrator"', query time: 0.04s Refine Results
  1. 281

    Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum. by Savio S Ferreira, Suman Pandey, Jesseca Hemminger, Serdar Bozdag, Mauricio S Antunes

    Published 2025-01-01
    “…Triggering these different defense processes requires orchestration of a network of proteins and RNA molecules that includes microRNAs (miRNAs). …”
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    Article
  2. 282

    Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response by Guo Liu, Feng Liu

    Published 2022-01-01
    “…Th2 immune response is essential for providing protection against pathogens and orchestrating humoral immunity. However, excessive Th2 immune response leads to the pathogenesis of Th2 inflammation diseases, including asthma, allergic rhinitis, and atopic dermatitis. …”
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    Article
  3. 283

    Stem Cells in Solid Tumors: Accumulated Evidence and Future Directions by Deepthi Venkatachalapathy, Parveen Doddamani, Aradya V Hirriyannaiah, Prashant Vishwanath, Suma Nataraj, Akila Prashant

    Published 2024-04-01
    “…These represent a minority subset of cells within a tumor, believed to orchestrate the relentless growth of the entire tumor. …”
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  4. 284

    R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania by Jeziel D. Damasceno, Emma M. Briggs, Marija Krasilnikova, Catarina A. Marques, Craig Lapsley, Richard McCulloch

    Published 2025-02-01
    “…This work provides a link between R-loop homeostasis and DNA replication timing in a eukaryotic parasite and demonstrates that orchestration of DNA replication dictates levels of genome plasticity in Leishmania.…”
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  5. 285

    Schwann cells in regeneration and cancer by Lan Zhang, Jiale Xie, Wenyu Dai, Bing Lu, Sheng Yi

    Published 2025-01-01
    “…Injury responses stimulate c-Jun activation in Schwann cells, drive epithelial-mesenchymal transition and cellular phenotypic changes, and induce the generation of reprogrammed repair Schwann cells to orchestrate peripheral nerve regeneration process. Schwann cells and/or Schwann cell-derived molecules are commonly used as supporting cells and/or neurotrophic factors to construct Schwann cell-based tissue-engineered nerve grafts for repairing severe peripheral nerve injury with long defects. …”
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  6. 286

    A Review on Software-Defined Networking for Internet of Things Inclusive of Distributed Computing, Blockchain, and Mobile Network Technology: Basics, Trends, Challenges, and Future... by Shakila Shafiq, Md. Sazzadur Rahman, Shamim Ahmed Shaon, Imtiaz Mahmud, A. S. M. Sanwar Hosen

    Published 2024-01-01
    “…The study articulates the challenges of managing and orchestrating IoT systems and how SDN can be used to address these challenges by enabling dynamic and flexible network configurations. …”
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  7. 287

    Coactivators in PPAR-Regulated Gene Expression by Navin Viswakarma, Yuzhi Jia, Liang Bai, Aurore Vluggens, Jayme Borensztajn, Jianming Xu, Janardan K. Reddy

    Published 2010-01-01
    “…Upon ligand activation, PPARs undergo conformational changes that facilitate the dissociation of corepressor molecules and invoke a spatiotemporally orchestrated recruitment of transcription cofactors including coactivators and coactivator-associated proteins. …”
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  8. 288
  9. 289

    The Role of Inflammatory Cytokines and lncRNAs in the Pathogenesis of Atherosclerosis and Other Inflammatory Diseases: Focus on Sarcoidosis and Alzheimer’s Disease by Aldona Sokołowska, Julia Buszek, Piotr Czerniak, Adrianna Antoszewska, Weronika Bargiel, Dominika Bąk, Halszka Wajdowicz, Mateusz Warzocha

    Published 2025-01-01
    “…Description of the State of Knowledge Inflammatory cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6), orchestrate immune responses that exacerbate endothelial dysfunction, foam cell formation, and plaque instability. …”
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  10. 290
  11. 291

    Mechanisms and environmental factors shaping the ecosystem of brain macrophages by Silvia Penati, Simone Brioschi, Zhangying Cai, Claudia Z. Han, Claudia Z. Han, Marco Colonna, Marco Colonna

    Published 2025-01-01
    “…Several works have partially unveiled the mechanisms orchestrating the development of microglia and BAMs in both mice and humans; however, many questions remain unanswered. …”
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  12. 292

    Piezo1-directed neutrophil extracellular traps regulate macrophage differentiation during influenza virus infection by Yuexin Wang, Qiuli Yang, Yingjie Dong, Likun Wang, Zhiyuan Zhang, Ruiying Niu, Yufei Wang, Yujing Bi, Guangwei Liu

    Published 2025-01-01
    “…In addition, Piezo1 integrates magnesium signalling and the SIRT2-hypoxia-inducible factor-1 alpha (HIF1α)-dependent pathway to orchestrate reciprocal M1 and M2 macrophage lineage commitment through neutrophil-derived NET DNA. …”
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  13. 293

    Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The “Invisible Man” of Bacterial Vaginosis? by Thomas Bertran, Patrick Brachet, Marjolaine Vareille-Delarbre, Julie Falenta, Annie Dosgilbert, Marie-Paule Vasson, Christiane Forestier, Arlette Tridon, Bertrand Evrard

    Published 2016-01-01
    “…In the genital mucosa, dendritic cells (DCs) sense bacteria of the microenvironment via receptors and then orchestrate the immune response by induction of different T cell subtypes. …”
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  14. 294

    A Decade of FGF Receptor Research in Bladder Cancer: Past, Present, and Future Challenges by Erica di Martino, Darren C. Tomlinson, Margaret A. Knowles

    Published 2012-01-01
    “…Fibroblast growth factors (FGFs) orchestrate a variety of cellular functions by binding to their transmembrane tyrosine-kinase receptors (FGFRs) and activating downstream signalling pathways, including RAS/MAPK, PLCγ1, PI3K, and STATs. …”
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  15. 295

    Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells by Eun Jung Kwak, Young Soon Lee, Eun Mi Choi

    Published 2012-01-01
    “…Skeletal turnover is orchestrated by a complex network of regulatory factors. …”
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  16. 296

    The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking by Daniel P. Neumann, Katherine A. Pillman, B. Kate Dredge, Andrew G. Bert, Caroline A. Phillips, Rachael Lumb, Yesha Ramani, Cameron P. Bracken, Brett G. Hollier, Luke A. Selth, Traude H. Beilharz, Gregory J. Goodall, Philip A. Gregory

    Published 2024-12-01
    “…Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the extent of alternative polyadenylation (APA) during EMT has not yet been explored. …”
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  17. 297

    Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells by Ying Yin, Liquan Zhou, Shuiqiao Yuan

    Published 2018-01-01
    “…Some other retrotransposons reside in the vicinity of endogenous genes and are capable of regulating nearby genes and cell fate, possibly through providing alternative promoters, regulatory modules, or orchestrating high-order chromatin assembly. In addition, retrotransposons may mediate epigenetic memory, regulate gene expression posttranscriptionally, defend virus infection, and so on. …”
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  18. 298

    INTERROGATING THE EFFECTS OF ARMED BANDITRY ON THE SOCIO-ECONOMIC DEVELOPMENT OF NIGERIA’S NORTH-CENTRAL REGION (2015-2022) by YUSUFU Ahmed Audu, ODAUDU Alfred Idachaba, ILEVBARE Igheoise Trust

    Published 2023-09-01
    “… Armed banditry has being a major security challenge confronting northern Nigeria in recent years. Attacks orchestrated by these armed bandits have continued to escalate, especially since 2015 when the Buhari administration came into power with attendant consequences of loss of human lives, destruction of property, displacement of persons, loss of livelihoods and disruption of socio-economic activities. …”
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  19. 299

    RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA by ADIGWE AUSTEEN NDUBUISI

    Published 2024-12-01
    “…The implications of this in the long run remains unpredictable but the effect of this in contemporary times is orchestrating outcomes that offers no heritage of good to all and sundry. …”
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  20. 300

    The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review by Wenhao Wu, Guoqiang Fan

    Published 2025-03-01
    “…Small RNAs (miRNAs) and long non-coding RNAs (lncRNAs) act as post-transcriptional regulators, orchestrating immune signaling and pathogen counter-defense strategies. …”
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    Article