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281
Early changes in microRNA expression in Arabidopsis plants infected with the fungal pathogen Fusarium graminearum.
Published 2025-01-01“…Triggering these different defense processes requires orchestration of a network of proteins and RNA molecules that includes microRNAs (miRNAs). …”
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282
Bach2: A Key Regulator in Th2-Related Immune Cells and Th2 Immune Response
Published 2022-01-01“…Th2 immune response is essential for providing protection against pathogens and orchestrating humoral immunity. However, excessive Th2 immune response leads to the pathogenesis of Th2 inflammation diseases, including asthma, allergic rhinitis, and atopic dermatitis. …”
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283
Stem Cells in Solid Tumors: Accumulated Evidence and Future Directions
Published 2024-04-01“…These represent a minority subset of cells within a tumor, believed to orchestrate the relentless growth of the entire tumor. …”
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284
R-loops acted on by RNase H1 influence DNA replication timing and genome stability in Leishmania
Published 2025-02-01“…This work provides a link between R-loop homeostasis and DNA replication timing in a eukaryotic parasite and demonstrates that orchestration of DNA replication dictates levels of genome plasticity in Leishmania.…”
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285
Schwann cells in regeneration and cancer
Published 2025-01-01“…Injury responses stimulate c-Jun activation in Schwann cells, drive epithelial-mesenchymal transition and cellular phenotypic changes, and induce the generation of reprogrammed repair Schwann cells to orchestrate peripheral nerve regeneration process. Schwann cells and/or Schwann cell-derived molecules are commonly used as supporting cells and/or neurotrophic factors to construct Schwann cell-based tissue-engineered nerve grafts for repairing severe peripheral nerve injury with long defects. …”
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286
A Review on Software-Defined Networking for Internet of Things Inclusive of Distributed Computing, Blockchain, and Mobile Network Technology: Basics, Trends, Challenges, and Future...
Published 2024-01-01“…The study articulates the challenges of managing and orchestrating IoT systems and how SDN can be used to address these challenges by enabling dynamic and flexible network configurations. …”
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287
Coactivators in PPAR-Regulated Gene Expression
Published 2010-01-01“…Upon ligand activation, PPARs undergo conformational changes that facilitate the dissociation of corepressor molecules and invoke a spatiotemporally orchestrated recruitment of transcription cofactors including coactivators and coactivator-associated proteins. …”
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288
miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma
Published 2025-01-01“…Overall, miR-449 and miR-340 orchestrate FN-RMS cell identity, positioning MPC inhibition as a strategy to shift FN-RMS cells toward a non-tumorigenic, quiescent state.…”
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289
The Role of Inflammatory Cytokines and lncRNAs in the Pathogenesis of Atherosclerosis and Other Inflammatory Diseases: Focus on Sarcoidosis and Alzheimer’s Disease
Published 2025-01-01“…Description of the State of Knowledge Inflammatory cytokines, including interleukin-1β (IL-1β), tumor necrosis factor-α (TNF-α), and interleukin-6 (IL-6), orchestrate immune responses that exacerbate endothelial dysfunction, foam cell formation, and plaque instability. …”
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290
The global RNA-binding protein RbpB is a regulator of polysaccharide utilization in Bacteroides thetaiotaomicron
Published 2025-01-01“…However, how PULs are orchestrated at translational level in response to the fluctuating levels of their cognate substrates is unknown. …”
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291
Mechanisms and environmental factors shaping the ecosystem of brain macrophages
Published 2025-01-01“…Several works have partially unveiled the mechanisms orchestrating the development of microglia and BAMs in both mice and humans; however, many questions remain unanswered. …”
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292
Piezo1-directed neutrophil extracellular traps regulate macrophage differentiation during influenza virus infection
Published 2025-01-01“…In addition, Piezo1 integrates magnesium signalling and the SIRT2-hypoxia-inducible factor-1 alpha (HIF1α)-dependent pathway to orchestrate reciprocal M1 and M2 macrophage lineage commitment through neutrophil-derived NET DNA. …”
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293
Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The “Invisible Man” of Bacterial Vaginosis?
Published 2016-01-01“…In the genital mucosa, dendritic cells (DCs) sense bacteria of the microenvironment via receptors and then orchestrate the immune response by induction of different T cell subtypes. …”
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294
A Decade of FGF Receptor Research in Bladder Cancer: Past, Present, and Future Challenges
Published 2012-01-01“…Fibroblast growth factors (FGFs) orchestrate a variety of cellular functions by binding to their transmembrane tyrosine-kinase receptors (FGFRs) and activating downstream signalling pathways, including RAS/MAPK, PLCγ1, PI3K, and STATs. …”
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295
Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells
Published 2012-01-01“…Skeletal turnover is orchestrated by a complex network of regulatory factors. …”
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296
The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking
Published 2024-12-01“…Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the extent of alternative polyadenylation (APA) during EMT has not yet been explored. …”
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297
Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells
Published 2018-01-01“…Some other retrotransposons reside in the vicinity of endogenous genes and are capable of regulating nearby genes and cell fate, possibly through providing alternative promoters, regulatory modules, or orchestrating high-order chromatin assembly. In addition, retrotransposons may mediate epigenetic memory, regulate gene expression posttranscriptionally, defend virus infection, and so on. …”
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298
INTERROGATING THE EFFECTS OF ARMED BANDITRY ON THE SOCIO-ECONOMIC DEVELOPMENT OF NIGERIA’S NORTH-CENTRAL REGION (2015-2022)
Published 2023-09-01“… Armed banditry has being a major security challenge confronting northern Nigeria in recent years. Attacks orchestrated by these armed bandits have continued to escalate, especially since 2015 when the Buhari administration came into power with attendant consequences of loss of human lives, destruction of property, displacement of persons, loss of livelihoods and disruption of socio-economic activities. …”
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299
RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA
Published 2024-12-01“…The implications of this in the long run remains unpredictable but the effect of this in contemporary times is orchestrating outcomes that offers no heritage of good to all and sundry. …”
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300
The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review
Published 2025-03-01“…Small RNAs (miRNAs) and long non-coding RNAs (lncRNAs) act as post-transcriptional regulators, orchestrating immune signaling and pathogen counter-defense strategies. …”
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