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261
La gobernanza regional compleja del comercio electrónico latinoamericano: una perspectiva comparada de la Alianza del Pacífico, la Comunidad Andina y el Mercosur
Published 2025-01-01“…Conclusions: The analysis shows that, within systems characterized by growing institutional density and diversity—such as the Latin American e-commerce environment—regional cooperation can be facilitated when regional trade agreements are embedded in a broader trade regime, where there is a clear sequencing among different agreements, and when orchestrators and policy networks are present. In contrast, their absence leads to ineffective agreement implementation and increased regional fragmentation. …”
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262
A scATAC-seq atlas of stasis zone in rat skin burn injury wound process
Published 2025-01-01“…Importantly, our analysis uncovered the regulatory networks governing these genes, offering valuable insights into the intricate mechanisms orchestrating burn wound healing. This comprehensive cellular and molecular atlas of the stasis zone provides a powerful resource for developing targeted therapies aimed at improving burn injury recovery and minimizing long-term consequences.…”
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263
Molecular logic for cellular specializations that initiate the auditory parallel processing pathways
Published 2025-01-01“…In particular, CN cell-type identity is encoded in a transcriptional architecture that orchestrates functionally congruent expression across a small set of gene families to customize projection patterns, input-output synaptic communication, and biophysical features required for encoding distinct aspects of acoustic signals. …”
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264
Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina
Published 2013-01-01“…Orchestrated proliferation, differentiation, and cell death contribute to the generation of the complex cytoarchitecture of the central nervous system, including that of the neuroretina. …”
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265
Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics
Published 2025-02-01“…Abstract Liver repair and regeneration are crucial physiological responses to hepatic injury and are orchestrated through intricate cellular and molecular networks. …”
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266
Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice
Published 2025-02-01“…These findings elucidate that distinct physiological perturbations in CA1 and CA3 place cells, coupled with disrupted hippocampal theta rhythmicity in CA1, potentially orchestrate the impairment of hippocampal-dependent spatial learning and memory in AD pathogenesis.…”
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267
Cell-specific functions of androgen receptor in skeletal muscles
Published 2024-05-01“…The varied mechanisms orchestrated by AR collectively influence the physiology of skeletal muscles.…”
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268
Alleviation of liver fibrosis by inhibiting a non-canonical ATF4-regulated enhancer program in hepatic stellate cells
Published 2025-01-01“…Mechanistically, TGFβ resets ATF4 to orchestrate a unique enhancer program for the transcriptional activation of pro-fibrotic EMT genes. …”
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269
Patient-specific therapeutic benefit of MuSK agonist antibody ARGX-119 in MuSK myasthenia gravis passive transfer models
Published 2025-02-01“…Summary: Muscle-specific kinase (MuSK) orchestrates the establishment and maintenance of neuromuscular synapses. …”
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270
The master male sex determinant Gdf6Y of the turquoise killifish arose through allelic neofunctionalization
Published 2025-01-01“…Deciphering how individual sex-determining genes orchestrate sex determination can reveal new actors in sexual development. …”
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271
Muscle Satellite Cells: Exploring the Basic Biology to Rule Them
Published 2016-01-01“…Every phase of satellite cell activity is highly regulated and orchestrated by many molecules and signaling pathways; the elucidation of players and mechanisms involved in satellite cell biology is of extreme importance, being the first step to expose the crucial points that could be modulated to extract the optimal response from these cells in therapeutic strategies. …”
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272
Regulation of the G1/S Transition in Hepatocytes: Involvement of the Cyclin-Dependent Kinase Cdk1 in the DNA Replication
Published 2012-01-01“…It also further confirms the well-orchestrated regulation of liver regeneration via multiple extracellular signals and pathways.…”
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273
Review of An Introduction to Atonal Music Analysis
Published 2017-09-01“…The review of this book also revealed that one may not find all aspects of atonal music in this book, and it still needs further resources to make a complete analysis of atonal music, particularly in aspects of harmony and orchestration. However, the book perfectly disuses pitch classes and pitch collection issues and to a good extent dodecaphonic music analysis. …”
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274
Deployment method for vEPC virtualized network function via Q-learning
Published 2017-08-01“…In the context of vEPC,a method of virtua1ized network function(VNF)dep1oyment via an improved Q-1earning a1gorithm was proposed to so1ve the prob1em that the existing methods cannot achieve the optimization of time de1ay and revenue of VNF dep1oyment simu1taneous1y.To get the optima1 dep1oyment po1icy in both space dimension and time dimension,a Markov decision process mode1 of vEPC service function chain dep1oyment on the basis of the traditiona1 0-1 programming mode1 was estab1ished and a so1ution with an improved Q-1earning a1gorithm was proposed.The method had taken fu11 consideration of both virtua1 network embedding in space dimension and orchestration of VNF 1ife cyc1e in time dimension,and thus,the mu1ti-objective optimization of revenue and de1ay cou1d be attained.Simu1ation shows that the method can reduce network de1ay whi1e increasing the revenue and the ratio of request acceptance compared with other dep1oyment methods.…”
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275
TAX PLANNING AND THE TIMELINESS OF FINANCIAL REPORTING IN LISTED MANUFACTURING FIRMS IN NIGERIA
Published 2024-12-01“…The study concludes that the delay on timely financial reporting orchestrated by tax planning is not significant enough to cause delays outside the statutory 90-day period. …”
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276
Astor Piazzolla’s compositional and interpretive styling of his Tango Adiós Nonino across four decades of his career – insights into the emergence of Nuevo Tango
Published 2025-12-01“…The most ‘revolutionary’ versions are arguably those arranged for and performed by Quintets from 1969 to 1983, the Conjunto 9 nonet from 1972, the electronic Octets from 1976 to 1977, and the orchestral version from 1985. Piazzolla’s style and the emergence of Nuevo Tango owes a great deal to his open collaborations with musicians of different backgrounds, approaching tango from classical, jazz, and even rock music perspectives. …”
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277
Computing satellite networks—the novel development of computing-empowered space-air-ground integrated networks
Published 2022-06-01“…Facing the increasing demands for computing ability and network access, the space-air-ground integrated networks in 6G systems is expected to surmount the limits on a single point of computing ability and traditional network transmission through the advantages of network cluster, where the novel space-air-ground integrated networks that deeply integrate cloud, edge, terminal, network, data, and computation is subsequently formed by taking computing ability as the core and network infrastructure as the foundation.Initially, the current situation and development in existing computing force networks and space-air-ground integrated networks (SAGIN) was introduced.Along with the demands for 6G computing-empowered space-air-ground integrated networks, the concept of satellite computing networks was defined and the co-existed system of computing capability and communication networks was further discussed.Then, the space networks, air networks, and ground networks of the layered satellite computing network architecture were discussed.Based on that, its logical network architecture that includes computing resource layer, computing abstract layer, and computing orchestration layer was further introduced.After that, the key technology enablers with respct to computing and storage issue, trusted transmission issue, satellite computing force addressing issue, and high-mobility computing force routing issue was discussed.Finally, the typical applicaiton scenarios of satellite computing networks and envision its future was presented.…”
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278
Ravel’s Programmatic Impulse
Published 2008-01-01“…Such a gap is hinted at in Berlioz’s own account of the program for the Symphonie Fantastique: »The aim of the program is by no means to copy faithfully what the composer has tried to present in orchestral terms, as some people seem to think; on the contrary, it is precisely in order to fill in the gaps which the use of musical language unavoidably leaves in the development of dramatic thought, that the composer has had to avail himself of written prose to explain and justify the outline of the symphony«.While Berlioz’s statement posits one sort of gap at the heart of the program/music relationship, it becomes more relevant to Ravel’s music to consider the gap from the other direction and reverse Berlioz’s terms: thus the composer avails himself of the unique structural and expressive resources of music to connote their own meaning, in order to fill in the gaps which the limitations of the programmatic source unavoidably leave in the development of dramatic thought.…”
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279
Early life stress shifts critical periods and causes precocious visual cortex development.
Published 2024-01-01“…Overall, the data suggest that ELS desynchronizes the orchestrated temporal sequence of regional brain development potentially leading to long-term functional deficiencies. …”
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280
The RNA-dependent association of phosphatidylinositol 4,5-bisphosphate with intrinsically disordered proteins contribute to nuclear compartmentalization.
Published 2024-12-01“…Thus, we propose that PIP2 spatiotemporally orchestrates nuclear processes through association with RNA and RDPA proteins and affects their ability to form foci presumably via phase separation. …”
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