Slight Pro-Inflammatory Immunomodulation Properties of Dendritic Cells by Gardnerella vaginalis: The “Invisible Man” of Bacterial Vaginosis? by Thomas Bertran, Patrick Brachet, Marjolaine Vareille-Delarbre, Julie Falenta, Annie Dosgilbert, Marie-Paule Vasson, Christiane Forestier, Arlette Tridon, Bertrand Evrard

“…In the genital mucosa, dendritic cells (DCs) sense bacteria of the microenvironment via receptors and then orchestrate the immune response by induction of different T cell subtypes. …”
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A Decade of FGF Receptor Research in Bladder Cancer: Past, Present, and Future Challenges by Erica di Martino, Darren C. Tomlinson, Margaret A. Knowles

“…Fibroblast growth factors (FGFs) orchestrate a variety of cellular functions by binding to their transmembrane tyrosine-kinase receptors (FGFRs) and activating downstream signalling pathways, including RAS/MAPK, PLCγ1, PI3K, and STATs. …”
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Effect of Magnolol on the Function of Osteoblastic MC3T3-E1 Cells by Eun Jung Kwak, Young Soon Lee, Eun Mi Choi

“…Skeletal turnover is orchestrated by a complex network of regulatory factors. …”
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The landscape of alternative polyadenylation during EMT and its regulation by the RNA-binding protein Quaking by Daniel P. Neumann, Katherine A. Pillman, B. Kate Dredge, Andrew G. Bert, Caroline A. Phillips, Rachael Lumb, Yesha Ramani, Cameron P. Bracken, Brett G. Hollier, Luke A. Selth, Traude H. Beilharz, Gregory J. Goodall, Philip A. Gregory

“…Epithelial-mesenchymal transition (EMT) plays important roles in tumour progression and is orchestrated by dynamic changes in gene expression. While it is well established that post-transcriptional regulation plays a significant role in EMT, the extent of alternative polyadenylation (APA) during EMT has not yet been explored. …”
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Enigma of Retrotransposon Biology in Mammalian Early Embryos and Embryonic Stem Cells by Ying Yin, Liquan Zhou, Shuiqiao Yuan

“…Some other retrotransposons reside in the vicinity of endogenous genes and are capable of regulating nearby genes and cell fate, possibly through providing alternative promoters, regulatory modules, or orchestrating high-order chromatin assembly. In addition, retrotransposons may mediate epigenetic memory, regulate gene expression posttranscriptionally, defend virus infection, and so on. …”
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INTERROGATING THE EFFECTS OF ARMED BANDITRY ON THE SOCIO-ECONOMIC DEVELOPMENT OF NIGERIA’S NORTH-CENTRAL REGION (2015-2022) by YUSUFU Ahmed Audu, ODAUDU Alfred Idachaba, ILEVBARE Igheoise Trust

“… Armed banditry has being a major security challenge confronting northern Nigeria in recent years. Attacks orchestrated by these armed bandits have continued to escalate, especially since 2015 when the Buhari administration came into power with attendant consequences of loss of human lives, destruction of property, displacement of persons, loss of livelihoods and disruption of socio-economic activities. …”
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RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA by ADIGWE AUSTEEN NDUBUISI

“…The implications of this in the long run remains unpredictable but the effect of this in contemporary times is orchestrating outcomes that offers no heritage of good to all and sundry. …”
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The role of epigenetics in plant pathogens interactions under the changing environments: A systematic review by Wenhao Wu, Guoqiang Fan

“…Small RNAs (miRNAs) and long non-coding RNAs (lncRNAs) act as post-transcriptional regulators, orchestrating immune signaling and pathogen counter-defense strategies. …”
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PANoptosis in intestinal epithelium: its significance in inflammatory bowel disease and a potential novel therapeutic target for natural products by Chuanxiang Zhao, Shan Lin

“…Ample evidence has revealed substantial mechanistic convergence and intricate crosstalk among these three aforementioned forms of cell death, expanding the conceptualization of PANoptosis orchestrated by the PNAoptosome complex. This review provides a concise overview of the molecular mechanisms of apoptosis, necroptosis, and pyroptosis. …”
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Pluripotency Factors on Their Lineage Move by Clair E. Weidgang, Thomas Seufferlein, Alexander Kleger, Martin Mueller

“…However, detailed underlying insights into how these transcription factors orchestrate cell fate decisions remain largely elusive. …”
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RETHINKING CLIMATE CHANGE AND NATIONAL SECURITY: IMPLICATIONS FOR SUSTAINABLE DEVELOPMENT IN NIGERIA by AUSTEEN NDUBUISI ADIGWE

“…The implications of this in the long run remains unpredictable but the effect of this in contemporary times is orchestrating outcomes that offers no heritage of good to all and sundry. …”
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Monocyte-Derived Macrophages Are Impaired in Myelodysplastic Syndrome by Yu Han, Huaquan Wang, Zonghong Shao

“…Macrophages are innate immune cells that ingest and degrade abnormal cells, debris, and foreign material and orchestrate inflammatory processes. We analyzed the role of macrophages from MDS patients in vitro. …”
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Costimulatory Pathways: Physiology and Potential Therapeutic Manipulation in Systemic Lupus Erythematosus by Nien Yee Kow, Anselm Mak

“…Indeed, SLE is characterized by an orchestrated interplay amongst different types of immunopathologically important cells participating in both innate and adaptive immunity including the dendritic cells, macrophages, neutrophils and lymphocytes, as well as traditional nonimmune cells such as endothelial, epithelial, and renal tubular cells. …”
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Detection of Jihadism in Social Networks Using Big Data Techniques Supported by Graphs and Fuzzy Clustering by Cristina Sánchez-Rebollo, Cristina Puente, Rafael Palacios, Claudia Piriz, Juan P. Fuentes, Javier Jarauta

“…The research presented in this paper focuses on the analysis of Twitter messages to detect the leaders orchestrating terrorist networks and their followers. …”
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Extending OpenStack Monasca for Predictive Elasticity Control by Giacomo Lanciano, Filippo Galli, Tommaso Cucinotta, Davide Bacciu, Andrea Passarella

“…This paper introduces an architecture for predictive cloud operations, which enables orchestrators to apply time-series forecasting techniques to estimate the evolution of relevant metrics and take decisions based on the predicted state of the system. …”
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The Switchmaze: an open-design device for measuring motivation and drive switching in mice by Hartmann, Clara, Mahajan, Ambika, Borges, Vinicius, Razenberg, Lotte, Thönnes, Yves, Karnani, Mahesh Miikael

“…However, how the brain orchestrates switching between the neural mechanisms controlling motivated behaviours, or drives, is unknown. …”
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Myogenesis gone awry: the role of developmental pathways in rhabdomyosarcoma by Annika L. Gustafson, Annika L. Gustafson, Annika L. Gustafson, Adam D. Durbin, Kristin B. Artinger, Heide L. Ford, Heide L. Ford, Heide L. Ford

“…During normal myogenesis, these developmental transcription factors (TFs) orchestrate the formation of terminally differentiated, striated, and multinucleated skeletal muscle. …”
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Genome-Wide Identification and Expression Profiling of the <i>SPL</i> Transcription Factor Family in Response to Abiotic Stress in Centipedegrass by Dandan Kong, Maotao Xu, Siyu Liu, Tianqi Liu, Boyang Liu, Xiaoyun Wang, Zhixiao Dong, Xiao Ma, Junming Zhao, Xiong Lei

“…SQUAMOSA promoter-binding protein-like (SPL) transcription factors play a critical role in the regulation of gene expression and are indispensable in orchestrating plant growth and development while also improving resistance to environmental stressors. …”
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Cancer-Associated Immune Resistance and Evasion of Immune Surveillance in Colorectal Cancer by Pietro Parcesepe, Guido Giordano, Carmelo Laudanna, Antonio Febbraro, Massimo Pancione

“…The development of cancer-specific “immune resistance” can be orchestrated either by cooperation with tumor microenvironment or by successive rounds of genetic/epigenetic changes. …”
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Dual Effect of Serum Amyloid A on the Invasiveness of Glioma Cells by Franciele Hinterholz Knebel, Renata Chaves Albuquerque, Renato Ramos Massaro, Silvya Stuchi Maria-Engler, Ana Campa

“…These findings agree with the effect triggered by rSAA on matrix metalloproteinases (MMPs) activities measured in a gelatinolytic assay. rSAA inhibited activity of both MMPs in A172 cells while increasing them in T98G cells. rSAA also affected the production of compounds present in the tumor microenvironment that orchestrate tumor progression, such as IL-8, the production of reactive oxygen species (ROS) and nitric oxide (NO). …”
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