High-integrated photonic tensor core utilizing high-dimensional lightwave and microwave multidomain multiplexing by Xiangyan Meng, Nuannuan Shi, Guojie Zhang, Junshen Li, Ye Jin, Shiyou Sun, Yichen Shen, Wei Li, Ninghua Zhu, Ming Li

“…Through the independent tuning of multiwavelength lasers, the operational capabilities of an MRR are orchestrated, culminating in the formation of an optical tensor core. …”
Get full text

Secretory Products of Trichinella spiralis Muscle Larvae and Immunomodulation: Implication for Autoimmune Diseases, Allergies, and Malignancies by Ljiljana Sofronic-Milosavljevic, Natasa Ilic, Elena Pinelli, Alisa Gruden-Movsesijan

“…From this immunologically privileged place, the parasite orchestrates a long-lasting molecular cross talk with the host through muscle larvae excretory-secretory products (ES L1). …”
Get full text

Targeting the Interplay Between Autophagy and the Nrf2 Pathway in Parkinson’s Disease with Potential Therapeutic Implications by Mengru Liu, Siqi Liu, Zihan Lin, Xi Chen, Qian Jiao, Xixun Du, Hong Jiang

“…This review overviews the role of autophagy and nuclear factor erythroid 2-related factor 2 (Nrf2), a pivotal transcriptional regulator orchestrating cellular defense mechanisms against oxidative stress, and the complex interplay between these processes. …”
Get full text

Evolutionary conserved regulation of TFEB stability by the E3 ubiquitin ligase WWP2 modulates response to stress in vivo by Juan A. Garcia-Sanchez, Estelle Bonnet, Céline Loubatier, Anne Doye, Guillaume Paillier, Fabien Segui, Frédéric Larbret, Paul Chaintreuil, Ludovic Batistic, Cédric Torre, Marcel Deckert, Jolanta Polanowska, Patrick Munro, Laurent Boyer, Orane Visvikis

“…Summary: Transcription factor EB (TFEB) is a key transcription factor that orchestrates the cellular response to stress. Dysregulation of TFEB is associated with a range of human diseases, and understanding the regulatory mechanisms of TFEB is crucial for identifying potential drug targets. …”
Get full text

Adipokines regulate the development and progression of MASLD through organellar oxidative stress by Ke Zhao, Heng Zhang, Wenyu Ding, Xiaoshuai Yu, Yanli Hou, Xihong Liu, Xinhua Li, Xiaolei Wang

“…These adipokines intricately orchestrate regulatory pathways that impact glucose and lipid metabolism, oxidative stress, and mitochondrial function, thereby influencing the evolution of hepatic steatosis and progression to metabolic dysfunction–associated steatohepatitis (MASH). …”
Get full text

Sonic hedgehog and fibroblast growth factor 8 regulate the evolution of amniote facial proportions by Marta Marchini, Greta Keller, Naaz Khan, Rushabh Shah, Adriana Saliceti Galarza, Katherine B. Starr, Alexandra Apostopoulos, Thomas J. Sanger

“…In birds, this is orchestrated by domains of Shh and Fgf8 expression, known as the frontonasal ectodermal zone (FEZ). …”
Get full text

An Overview of the Role of Innate Lymphoid Cells in Gut Infections and Inflammation by Silvia Sedda, Irene Marafini, Michele M. Figliuzzi, Francesco Pallone, Giovanni Monteleone

“…ILCs represent a relatively small population in the gut, but accumulating evidence suggests that these cells could play a decisive role in orchestrating both protective and detrimental immune responses. …”
Get full text

Anisotropic structure of nanofiber hydrogel accelerates diabetic wound healing via triadic synergy of immune-angiogenic-neurogenic microenvironments by Kunkoo Kim, Jia Yang, Chengli Li, Chun-Yi Yang, Peilun Hu, Yaosai Liu, Yin-yuan Huang, Xiaohan Sun, Ming Chi, Chenyu Huang, Xiaodan Sun, Lingyun Zhao, Xiumei Wang

“…The physical signals of structural anisotropy offer significant potential for orchestrating multicellular regulation through physical contact and cellular mechanosensing pathways, irrespective of cell type. …”
Get full text

Gut Mesenchymal Stromal Cells in Immunity by Valeria Messina, Carla Buccione, Giulia Marotta, Giovanna Ziccheddu, Michele Signore, Gianfranco Mattia, Rossella Puglisi, Benedetto Sacchetti, Livia Biancone, Mauro Valtieri

“…Among their multiple functions, MSCs closely interact with immune cells, orchestrating their activity to maintain overall homeostasis. …”
Get full text

Magnetic Source Detection Using an Array of Planar Hall Effect Sensors and Machine Learning Algorithms by Miki Vizel, Roger Alimi, Daniel Lahav, Moty Schultz, Asaf Grosz, Lior Klein

“…The main electronic card orchestrates their measurement by supplying the required driving current and amplifying and sampling their output in a synchronized manner. …”
Get full text

The autophagy component LC3 regulates lymphocyte adhesion via LFA1 transport in response to outside-in signaling by Naoyuki Kondo, Yuko Mimori-Kiyosue, Keizo Tokuhiro, Giuseppe Pezzotti, Tatsuo Kinashi

“…Abstract The leukocyte integrin LFA1 is indispensable for immune responses, orchestrating lymphocyte trafficking and adhesion. While LFA1 activation induces LFA1 clustering at the cell contact surface via outside-in signaling, the regulatory mechanisms remain unclear. …”
Get full text

A critical review on phytochemical profile and health promoting effects of mung bean (Vigna radiata) by Kumar Ganesan, Baojun Xu

“…Botanical, phytochemical and pharmacological information was gathered and orchestrated. Remarkable studies have been demonstrated, showing the enhancement of metabolites in mung bean during the sprouting process, which possesses various health benefiting bioactive compounds. …”
Get full text

Myogenic differentiation markers in muscle tissue after aerobic training by Rastegar Hoseini, Zahra Hoseini, Ayob Kamangar

“…These pathways play pivotal roles in orchestrating the expression and activity of MDFs, ultimately influencing muscle adaptation and regeneration. …”
Get full text

La gobernanza regional compleja del comercio electrónico latinoamericano: una perspectiva comparada de la Alianza del Pacífico, la Comunidad Andina y el Mercosur by Julissa Castro-Silva

“…Conclusions: The analysis shows that, within systems characterized by growing institutional density and diversity—such as the Latin American e-commerce environment—regional cooperation can be facilitated when regional trade agreements are embedded in a broader trade regime, where there is a clear sequencing among different agreements, and when orchestrators and policy networks are present. In contrast, their absence leads to ineffective agreement implementation and increased regional fragmentation. …”
Get full text

A scATAC-seq atlas of stasis zone in rat skin burn injury wound process by Ruikang Li, Jiashan Li, Shuai Liu, Xinya Guo, Jianyu Lu, Tao Wang, Tao Wang, Junjie Chen, Yue Zheng, Yue Yuan, Jiaxin Du, Jiaxin Du, Bolin Zhu, Bolin Zhu, Xiaoyu Wei, Pengcheng Guo, Longqi Liu, Longqi Liu, Xun Xu, Xi Dai, Runzhi Huang, Xin Liu, Xin Liu, Xiaoyan Hu, Shiwei Wang, Shizhao Ji

“…Importantly, our analysis uncovered the regulatory networks governing these genes, offering valuable insights into the intricate mechanisms orchestrating burn wound healing. This comprehensive cellular and molecular atlas of the stasis zone provides a powerful resource for developing targeted therapies aimed at improving burn injury recovery and minimizing long-term consequences.…”
Get full text

Molecular logic for cellular specializations that initiate the auditory parallel processing pathways by Junzhan Jing, Ming Hu, Tenzin Ngodup, Qianqian Ma, Shu-Ning Natalie Lau, M. Cecilia Ljungberg, Matthew J. McGinley, Laurence O. Trussell, Xiaolong Jiang

“…In particular, CN cell-type identity is encoded in a transcriptional architecture that orchestrates functionally congruent expression across a small set of gene families to customize projection patterns, input-output synaptic communication, and biophysical features required for encoding distinct aspects of acoustic signals. …”
Get full text

Early Neural Cell Death Is an Extensive, Dynamic Process in the Embryonic Chick and Mouse Retina by Teresa Chavarría, Jimena Baleriola, Raquel Mayordomo, Flora de Pablo, Enrique J. de la Rosa

“…Orchestrated proliferation, differentiation, and cell death contribute to the generation of the complex cytoarchitecture of the central nervous system, including that of the neuroretina. …”
Get full text

Molecular mechanisms in liver repair and regeneration: from physiology to therapeutics by Xiao Ma, Tengda Huang, Xiangzheng Chen, Qian Li, Mingheng Liao, Li Fu, Jiwei Huang, Kefei Yuan, Zhen Wang, Yong Zeng

“…Abstract Liver repair and regeneration are crucial physiological responses to hepatic injury and are orchestrated through intricate cellular and molecular networks. …”
Get full text

Distinct disruptions in CA1 and CA3 place cell function in Alzheimer’s disease mice by Sanggeon Park, Mijeong Park, Eun Joo Kim, Jeansok J. Kim, Jeiwon Cho, Yeowool Huh

“…These findings elucidate that distinct physiological perturbations in CA1 and CA3 place cells, coupled with disrupted hippocampal theta rhythmicity in CA1, potentially orchestrate the impairment of hippocampal-dependent spatial learning and memory in AD pathogenesis.…”
Get full text

Cell-specific functions of androgen receptor in skeletal muscles by Hiroshi Sakai, Yuuki Imai

“…The varied mechanisms orchestrated by AR collectively influence the physiology of skeletal muscles.…”
Get full text