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181
Aberrant Regulation of Messenger RNA 3′-Untranslated Region in Human Cancer
Published 2007-01-01“…The 3′UTR governs gene expression via orchestrated interactions between mRNA structural components (cis-elements) and specific trans-acting factors (RNA-binding proteins and non-coding RNAs). …”
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182
Model Architecture Analysis and Implementation of TENET for Cell–Cell Interaction Network Reconstruction Using Spatial Transcriptomics Data
Published 2025-02-01“…Cellular communication relies on the intricate interplay of signaling molecules, which come together to form the cell–cell interaction (CCI) network that orchestrates tissue behavior. Researchers have shown that shallow neural networks can effectively reconstruct the CCI from the abundant molecular data captured in spatial transcriptomics (ST). …”
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183
Les institutions et les acteurs en santé au travail au Québec et en France : regard croisé
Published 2010-02-01“…The Québec law of December 21, 1979, orchestrating its entire organization, placed the Commission de la santé et de la sécurité du travail (workers’ compensation board) at its centre. …”
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184
The role of immunity in insulin resistance in patients with polycystic ovary syndrome
Published 2025-01-01“…Therefore, this review aims to elucidate the interplay between IR in PCOS patients, the controlled immune response orchestrated by immune cells and immunomodulatory molecules, and their interactions with adipocytes, hyperandrogenemia, chronic inflammation, and metabolic homeostasis.…”
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185
The Guidebook and the Medicine Pole: Staging Memory at a Nineteenth Century Battle Site in the American West
Published 2017-04-01“…Visitors to the Lava Beds National Monument discover a site where the National Park Service has to orchestrate features of geological, historical, and environmental interest. …”
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186
Budgets participatifs : S’approprier la dialectique de la gouvernance participative locale
Published 2017-06-01“…In Tunisia and Morocco, Participatory Budgeting (PB) seems to offer a bottom-up counterpoint to the dynamics of citizen participation as it is understood or orchestrated by the central authorities. Tailor made PB conventions in which inhabitants, local representatives and local administrations define a set of rules adapted to local specificities present an alternative to the rigid mechanisms defined by the Ministry of the Interior. …”
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187
The Golgi in Cell Migration: Regulation by Signal Transduction and Its Implications for Cancer Cell Metastasis
Published 2012-01-01“…Uncovering the regulatory network that orchestrates cell migration is of fundamental importance for the development of new therapeutic strategies against cancer cell metastasis.…”
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188
Polarity Determinants in Dendritic Spine Development and Plasticity
Published 2016-01-01“…Although many questions remain unanswered in our understanding of how polarity proteins regulate spine development and plasticity, current and future research will undoubtedly shed more light on how this conserved group of proteins orchestrates different pathways to shape the neuronal circuitry.…”
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189
La marque : entité spirituelle ou religieuse ?
Published 2022-10-01“…Author of numerous books and articles, Heilbrunn regularly discussed the convergence between religion and brands by looking at how their economy resolves around the mystery of the Trinity through the three complementary sides of an absent god: a “sensorial” side, linked to the material products of the consumer good and to its tangible aspects, directly prehensile by consumers; a “rhetoric” side, which refers to the ideological dimension of the brand, to its place and its capacity to convey values and imagination; a “pragmatic” side, which points towards engaging corporal practices and which orchestrate, among others, the rituals of buying and consumption.…”
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190
« Ever step you take is forever » : fin de l’héroïsme et vacuité spirituelle dans No Country for Old Men
Published 2023-01-01“…As a philosophical step orchestrated by the Coens, what seems to be missing or elided from the novel by Cormac McCarthy elicits a tumble into chaos. …”
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191
Temporal expression of bacterial proteins instructs host CD4 T cell expansion and Th17 development.
Published 2012-01-01“…Thus, pathogen regulation of antigen expression plays a major role in orchestrating the expansion, differentiation, and location of antigen-specific CD4 T cells in vivo.…”
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192
Evanghelia apocrifă a Martei Petreu: identităţi elective – corporalitate afectivă
Published 2014-12-01“…And this happens mainly because Marta Petreu proves to be a skilled, self-centered orchestrator of inner degradation. The concept is Marta Petreu’s ontological space where she isolates herself looking for semantic and linguistic uniqueness among other feminine Romanian voices of her generation. …”
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193
On the involvement of the second heart field in congenital heart defects
Published 2024-03-01“…SHF deployment creates the template for subsequent cardiac septation and has been implicated in cardiac looping and in orchestrating outflow tract development with neural crest cells. …”
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194
A Role for PPARβ/δ in Tumor Stroma and Tumorigenesis
Published 2008-01-01“…Recent evidence suggests that stromal PPARβ/δ regulates tumor endothelial cell proliferation and promotes differentiation leading to the properly orchestrated events required for tumor blood vessel formation. …”
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195
Surveillance, Phagocytosis, and Inflammation: How Never-Resting Microglia Influence Adult Hippocampal Neurogenesis
Published 2014-01-01“…Microglia cells are the major orchestrator of the brain inflammatory response. As such, they are traditionally studied in various contexts of trauma, injury, and disease, where they are well-known for regulating a wide range of physiological processes by their release of proinflammatory cytokines, reactive oxygen species, and trophic factors, among other crucial mediators. …”
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196
Methodology for the Automatic Generation of Optimization Models of Systems of Flexible Energy Resources
Published 2025-01-01“…Typically, the operation of flexible energy resources is orchestrated through optimization models. However, the manual creation of these models is a complex and error-prone task, often requiring the expertise of domain specialists. …”
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197
Peritoneal Adipocytes and Their Role in Inflammation during Peritoneal Dialysis
Published 2010-01-01“…Adipose tissue synthesizes different adipokines and cytokines that orchestrate and regulate inflammation, insulin action, and glucose metabolism locally and systemically. …”
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198
The Dendritic Cell-Regulatory T Lymphocyte Crosstalk Contributes to Tumor-Induced Tolerance
Published 2011-01-01“…In turn, Treg that expand during tumor progression contribute to the immune tolerance of cancer by impeding DCs' ability to orchestrate immune responses and by directly inhibiting antitumoral T lymphocytes. …”
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199
Policy conflict detection in software defined network by using deep learning
Published 2017-11-01“…In OpenFlow-based SDN(software defined network),applications can be deployed through dispatching the flow polices to the switches by the application orchestrator or controller.Policy conflict between multiple applications will affect the actual forwarding behavior and the security of the SDN.With the expansion of network scale of SDN and the increasement of application number,the number of flow entries will increase explosively.In this case,traditional algorithms of conflict detection will consume huge system resources in computing.An intelligent conflict detection approach based on deep learning was proposed which proved to be efficient in flow entries’ conflict detection.The experimental results show that the AUC (area under the curve) of the first level deep learning model can reach 97.04%,and the AUC of the second level model can reach 99.97%.Meanwhile,the time of conflict detection and the scale of the flow table have a linear growth relationship.…”
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200
Polarity and migration of cranial and cardiac neural crest cells: underlying molecular mechanisms and disease implications
Published 2025-01-01“…The main cellular mechanisms that sustain this migration include contact inhibition of locomotion, co-attraction, chemotaxis and mechanical cues from the surrounding environment, all regulated by proteins that orchestrate cell polarity and motility. In this review we highlight the molecular mechanisms involved in neural crest cell migration and polarity, focusing on the role of small GTPases, Heterotrimeric G proteins and planar cell polarity complex. …”
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