Enhanced intestinal epithelial co-culture model with orbital mechanical stimulation: a proof-of-concept application in food nanotoxicology by Mattia Santoni, Giovanni Piccinini, Giovanni Piccinini, Giovanni Liguori, Maria Roberta Randi, Massimo Baroncini, Liliana Milani, Francesca Danesi

“…Here, we developed an enhanced Caco-2/HT29-MTX-E12 co-culture model incorporating orbital mechanical stimulation to better replicate intestinal conditions and investigate nanoparticle interactions.MethodsWe established co-cultures under static and dynamic conditions, evaluating their development through multiple approaches including barrier integrity measurements, gene expression analysis, and confocal microscopy. …”
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Pulse-profile Modeling and Spin–Orbit Alignment in a Suzaku Sample of Accreting X-Ray Binary Pulsars by Silas G. T. Laycock, Rigel C. Cappallo, Pragati Pradhan, Dimitris M. Christodoulou, Biswajit Paul

“…This is because masses in binary systems overwhelmingly come from an orbital-mechanics formulation (Kepler’s third law), in which the dominant source of uncertainty is the inclination of the orbital plane.…”
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Pattern Strabismus: Where Does the Brain's Role End and the Muscle's Begin? by Fatema F. Ghasia, Aasef G. Shaikh

“…Speculated pathophysiology includes oblique muscle dysfunction, loss of fusion with altered recti muscle pull, displacements and instability in connective tissue pulleys of the recti muscles, vestibular hypofunction, and abnormal neural connections. Orbital mechanical factors, such as abnormal pulleys, were reported as a cause of pattern strabismus in patients with craniofacial anomalies, connective tissue disorders, and late-onset strabismus. …”
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