Anticancer and Antioxidant Activities of Methanolic Extract of Ziziphus Spina-Christi Leaves against Human Gastric Carcinoma Cells by Samir Abdulkarim Alharbi

“…Earlier reports revealed that it is cytotoxic to oral cancer cells. Objective: The current study determined the antioxidant activity and the anticancer potential of methanolic extract of Z. spina-christi against gastric carcinoma. …”
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Spontaneously Regressing Neonatal Oral Aphthous Ulceration of the Palate by Sandara Wayangi Madurapperuma, Andra Hennadige Heshan Malinga Jayaweera, Ruwan Duminda Jayasinghe

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Fluctuating Roles of Matrix Metalloproteinase-9 in Oral Squamous Cell Carcinoma by Suvi-Tuuli Vilen, Tuula Salo, Timo Sorsa, Pia Nyberg

“…One hallmark of cancer is the degradation of the extracellular matrix (ECM), which is caused by proteinases. In oral cancers, matrix metalloproteinases (MMPs), especially MMP-9, are associated with this degradation. …”
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A case of spindle cell squamous cell carcinoma of the tongue complicated by verrucous carcinoma by Yusuke Matsuzaki, Daiki Saito, Saimon Yasuhara, Yukio Watabe, Shiro Shigematsu

“…We report herein a highly unusual case of spindle cell squamous cell carcinoma (SCSCC), a rare form of oral cancer, co-occurring with verrucous carcinoma. …”
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Expression of interleukin-17 in oral tongue squamous cell carcinoma and its effect on biological behavior by Lina Jiang, Zhenghao Ma, Luwen Song, Chenchen Zhu, Jiancheng Li, Zhenxing Su, Hongsheng Liu

“…Abstract Tongue squamous cell carcinoma (TSCC) is a common malignant oral cancer characterized by substantial invasion, a high rate of lymph node and distant metastasis, and a high recurrence rate. …”
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Oral Squamous Cell Carcinoma: Features and Medico-Legal Implications of Diagnostic Omission by Davide Albano, Antonina Argo, Giuseppa Bilello, Enzo Cumbo, Melania Lupatelli, Pietro Messina, Fabio Massimo Sciarra, Mario Sessa, Stefania Zerbo, Giuseppe Alessandro Scardina

“…This study is aimed at examining in depth, through the presentation of a specific clinical case, the medico-legal aspects inherent to the diagnosis of oral cancer, analyzing the preventive, interceptive, and diagnostic strategies, the legal implications of clinical evaluation errors and diagnostic omission, and the type of medical damage produced and professional liability. …”
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Benefits of surgical obturators in oral maxillofacial rehabilitation. Review of literature by Madelaine Bárbara Jiménez Gutiérrez, José Miguel Robaina Ruiz, Iván Díaz Cal

“…<br /><strong>Methods:</strong> Study of bibliographic review in 64 publications between 1978-2019 on the use of obturator prosthesis. 153 documents from the MEDLINE, PubMed and SciELO reference systems databases were consulted, screened and indexed on the Web of Sciences, Scopus, Redalyc and Latindex, with the use of the following descriptors: oral obturator, obturator prosthesis, oral cancer. <br /><strong>Development:</strong> Prosthetic or palatal obturators are indicated to seal the surgically or congenitally exposed tissues of the oral cavity, and are a fundamental substitute for the hard palate, alveolar bone and surrounding soft tissues. …”
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Habitual khat chewing induced oral erythroplakia: A case report by Aisha A.H. Al-Jamaei, Khaled Al-Kebsi, ElhamA. Al-Qafaf, Mayada H.M. Hanash, R.V. Subramanyam, Jan G.A.M. de Visscher

“…Given that chewing khat is quite common in some Middle East and African countries, it is essential for oral health care professionals to be aware of its potential development of erythroplakia and oral cancer.…”
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Cytotoxic Effect of the Genus Sinularia Extracts on Human SCC25 and HaCaT Cells by Guey-Horng Wang, Tzung-Han Chou, Rong-Jyh Lin, Jyh-Horng Sheu, Shih-Hao Wang, Chia-Hua Liang

“…However, the mechanism underlying its activity against human oral cancer cells is poorly understood. This study evaluates the cyototoxicity effects of the genus Sinularia extracts (S. grandilobata, S. parva, S. triangula, S. scabra, S. nanolobata and S. gibberosa) by SCC25 and HaCaT cells. …”
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Concurrent squamous cell carcinoma and warthin tumor - A rare encounter by Sakshi Deorah, Shivanjali Raghuvanshi, Sharon John, Krachi Agarwal, Shalini Gupta

“…Oral cancer ranks sixth most common malignant neoplasm worldwide, with Squamous Cell Carcinoma being the predominant type observed in the head and neck region. …”
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An Investigation of Electrospun Clerodendrum phlomidis Leaves Extract Infused Polycaprolactone Nanofiber for In Vitro Biological Application by Siranjeevi Ravichandran, Rajesh Jegathaprathaban, Jeyalakshmi Radhakrishnan, R. Usha, V. Vijayan, Aklilu Teklemariam

“…PCL-CPM mats exposed to oral cancer (HSC-3) and renal cell carcinoma (ACHN) cell lines displayed promising anticancer activity with less than 50% survival rate after 24 h of incubation. 2,2-Diphenyl-1-picrylhydrazyl (DPPH) assay performed on PCL-CPM nanofibers revealed the antioxidant scavenging activity with maximum inhibition of 34% suggesting the role of the secondary metabolites release from scaffold. …”
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Analysis of Tobacco Cessation Programs in Dental Settings by Niharika Benjamin, Varsha Choubey, Meenakshi Bhasin, Bedkekar Sushma, Anushree Choudhary, Pallavi Ammu Thomas

“…Background: Tobacco use is a leading cause of preventable diseases, including oral cancer and periodontal disease. Dental settings offer a unique opportunity for tobacco cessation interventions due to the frequent patient–dentist interactions. …”
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Ectopic Oral Tonsillar Tissue: A Case Series with Bilateral and Solitary Presentations and a Review of the Literature by Masashi Kimura, Toru Nagao, Terumi Saito, Saman Warnakulasuriya, Hiroyuki Ohto, Akihito Takahashi, Kanji Komaki, Yoshiyuki Naganawa

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Tumor budding is a prognostic marker for overall survival and not for lymph node metastasis in Oral Squamous Cell Carcinoma – Systematic Review Update and Meta-Analysis by Gouri S. Panchannavar, Punnya V. Angadi

“…It highlights that TB is an important parameter for prognosis of oral cancer but its potential in prediction of LNM needs further validation.…”
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Attention-guided convolutional network for bias-mitigated and interpretable oral lesion classification by Adeetya Patel, Camille Besombes, Theerthika Dillibabu, Mridul Sharma, Faleh Tamimi, Maxime Ducret, Peter Chauvin, Sreenath Madathil

“…Abstract Accurate diagnosis of oral lesions, early indicators of oral cancer, is a complex clinical challenge. Recent advances in deep learning have demonstrated potential in supporting clinical decisions. …”
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Human Calmodulin-Like Protein CALML3: A Novel Marker for Normal Oral Squamous Mucosa That Is Downregulated in Malignant Transformation by Michael D. Brooks, Richard D. Bennett, Amy L. Weaver, Thomas J. Sebo, Steven E. Eckert, Emanuel E. Strehler, Alan B. Carr

“…Oral cancer is often diagnosed only at advanced stages due to a lack of reliable disease markers. …”
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A scoping review on the use of traditional medicine and oral health in Africa. by Moréniké Oluwátóyìn Foláyan, Mobolaji Timothy Olagunju, Olunike Rebecca Abodunrin, Omolola Titilayo Alade

“…Other oral disorders managed include halitosis, jaw fracture, and oral cancer.<h4>Conclusions</h4>Given the increasing prevalence of oral diseases within the region, the shortage of oral healthcare professionals and limited access to financial resources, it becomes imperative to support the generation of empirical evidence to enhance the provision of traditional medicine for oral healthcare in Africa.…”
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Statin drugs enhance responses to immune checkpoint blockade in head and neck cancer models by Chrystal Paulos, Gregory B Lesinski, Zachary S Buchwald, Nabil F Saba, Vikash Kansal, Andre J Burnham, Brendan L C Kinney, Nicole C Schmitt

“…Emerging data suggest that manipulation of cholesterol may enhance some aspects of antitumor immunity.Methods We used syngeneic murine models (mouse oral cancer, MOC1 and TC-1) to investigate our hypothesis that a subset of statin drugs would enhance antitumor immunity and delay tumor growth.Results Using an ex vivo coculture assay of murine cancer cells and tumor infiltrating lymphocytes, we discovered that all seven statin drugs inhibited tumor cell proliferation. …”
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Differential expression of DNA fragmentation factor 45 in leukoplakia and oral squamous cell carcinoma and its correlation with TNF-α levels by Sabitha Balakrishnan, Ramya Ramadoss, Rajashree Padmanaban, Rajkumar Krishnan

“…Conclusion: The absence of DFF-45 in oral cancer lesion suggests that this protein may suppress tumour progression. …”
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Resources for oral health in Africa by Moréniké Oluwátóyìn Foláyan, Moréniké Oluwátóyìn Foláyan, Ahmed Bhayat, Ahmed Bhayat, Sara S. Mikhail, Nicaise Ndembi, Maha El Tantawi, Maha El Tantawi

“…Currently, Africa has a very high prevalence of dental diseases, including untreated dental caries in permanent teeth, severe periodontal disease and oral cancer. Dental human resources are also very low, with dentists ranging from 1.77 to 0.03 per 10,000 population across the continent. …”
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