Association between the levels of urinary cell cycle biomarkers and non-recovery of renal function among critically ill geriatric patients with acute kidney injury by Li Cheng, Hui-Miao Jia, Xi Zheng, Yi-Jia Jiang, Xin Xin, Wen-Xiong Li

“…The regression model incorporating [TIMP-2]*[IGFBP7] demonstrated a fair predictive value (AUC 0.774, p < 0.001), with the optimal threshold set at 0.81 (ng/mL)2/1000. When [TIMP-2]*[IGFBP7] was combined with AKI severity and the APACHE score, the AUC increased to 0.851. …”
Get full text

Relationship between the latent profiles of health information-seeking behaviour and glycated haemoglobin levels in patients with type 2 diabetes: a cross-sectional survey in rural... by Xin Zhang, Lin Zeng, Yan-Ping Zhang, Jing-Feng Chen, Chao-Qun Bai, Xiao-Xue Lei, Gui-Fen Fu

“…We recommend that clinical medical professionals develop personalised health management education based on the various latent profile characteristics of patients to promote HISB and thereby achieve optimal glycaemic control.…”
Get full text

Deep-Learning-Based Land Cover Mapping in Franciacorta Wine Growing Area by Girma Tariku, Isabella Ghiglieno, Andres Sanchez Morchio, Luca Facciano, Celine Birolleau, Anna Simonetto, Ivan Serina, Gianni Gilioli

“…However, significant challenges remain in managing large, complex satellite imagery datasets, acquiring specialized datasets due to high costs and labor intensity, including a lack of comparative studies for the selection of optimal deep learning models. No less important is the scarcity of aerial datasets specifically tailored for agricultural areas. …”
Get full text

Injected Human Muscle Precursor Cells Overexpressing PGC-1α Enhance Functional Muscle Regeneration after Trauma by Deana Haralampieva, Souzan Salemi, Thomas Betzel, Ivana Dinulovic, Stefanie D. Krämer, Roger Schibli, Tullio Sulser, Christoph Handschin, Simon M. Ametamey, Daniel Eberli

“…Therefore, the first goal of our project was to optimize the functional regenerative potential of hMPC by genetic modification to overexpress human peroxisome proliferator-activated receptor gamma coactivator 1-alpha (hPGC-1α), key regulator of exercise-mediated adaptation. …”
Get full text

Long‐term survival outcome with tyrosine kinase inhibitors and surgical intervention in patients with metastatic or recurrent gastrointestinal stromal tumors: A 14‐year, single‐cen... by Jwa Hoon Kim, Min‐Hee Ryu, Changhoon Yoo, Heejung Chae, Hana Na, Moyoul Beck, Beom Su Kim, Moon‐Won Yoo, Jeong Hwan Yook, Byung Sik Kim, Ki‐Hun Kim, Chan Wook Kim, Yoon‐Koo Kang

“…Patients with advanced GIST showed better prognosis with the optimal use of imatinib, along with active surgical intervention and more common use of subsequent TKIs in period 2.…”
Get full text

A Shared Path: Co-occurrence and Clinical Implications of Celiac Disease and Type 1 Diabetes Mellitus by Wojciech Florczak, Joanna Śnieżna, Jakub Dziewic, Karol Dzwonnik, Wiktoria Domino, Urszula Zelik, Gabriela Trestka, Maria Przygoda, Jagienka Włodyka, Kamila Stępień, Sabina Adamczyk

“…Personalized treatment approaches seem to be essential for simultaneously managing and optimizing CeD and T1DM. However, the lower compliance to GFD among T1DM patients suggests the need for further research to provide support for long-term management of both T1DM and CeD. …”
Get full text

Diagnostic Accuracy of Shear Wave Elastography in Predicting Malignant Origins of Pleural Effusions in Emergency Departments by Rune Wiig Nielsen, Casper Falster, Stefan Posth, Niels Jacobsen, August Emil Licht, Rahul Bhatnagar, Christian Borbjerg Laursen

“…The objective of this study was to appraise the diagnostic accuracy of ultrasonographic findings associated with thoracic malignancy as well as to calculate the optimal cutoff values for SWE in this regard. <b>Methods</b>: Patients with a unilateral pleural effusion of unknown origin were included in the ED and subjected to a thoracic ultrasound (TUS) scan during their first 48 h after admittance. …”
Get full text

Sustainability index analysis of microalgae cultivated in biorefinery palm oil mill effluent by A. Santoso, T. Handayani, D. Pinardi, K. Kusrestuwardani, N. Widyastuti, I. Djarot, J. Haryanti, A. Sitomurni, H. Apriyanto

“…It is still necessary to do further research for the utilization of microalgae biomass into value-added products with an optimal, technically, economically, environmentally and socially sustainable system. …”
Get full text

Efforts to strengthen anatomic pathology diagnostic services for cancer in sub-Saharan Africa: a scoping review protocol by Katherine Van Loon, Elia John Mmbaga, Marcia Edelweiss, Dianna L. Ng, Asteria Herman Kimambo, Edda Vuhahula, Beatrice Paul Mushi, Omolade Adegoke, Johanna Goldberg, Pendo M. Ibrahim, Zainab Illonga, Julia Jackman, Luisa Jamisse

“…Although pathology services are essential to providing optimal oncological care, diagnostic capacity in sub-Saharan Africa is insufficient for the cancer burden. …”
Get full text

Comprehensive Evaluation of Quality Characteristics and Processing Suitability of Different Varieties of Large-fruited Sea Buckthorn Juice from Xinjiang Using Multivariate Analysis... by Rong HAN, Yan MA, Yu AO, Ting ZHANG, Xintao MENG, Mingqiang XU, Yan PAN

“…Overall, this study serves as an important reference for the selection of sea buckthorn varieties optimized for the production of large-fruited sea buckthorn juice.…”
Get full text

Drought-induced shifts in gross primary production pathways in Moso bamboo forests: Insights from improved BIOME-BGC and structural equation modeling by Zhaodong Zheng, Fangjie Mao, Huaqiang Du, Xuejian Li, Fengfeng Ye, Xianfeng Teng, Ningxin Yang, Jiacong Yu, Meixuan Song, Yinyin Zhao

“…In this study, photosynthetic water stress module of BIOME-BGC was improved and optimized by long-term carbon flux observations from the Anji MBF site, then the temporal variations of Gross Primary Production (GPP) were simulated and analyzed from 2000 to 2019. …”
Get full text

A new phase of China-ASEAN health cooperation: the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies by Jie Qiao, Siyan Zhan, Minghui Ren, Haijun Wang, Yangmu Huang, Zhenyu Zhang, Yanan Luo, Hui Yin, Zhongwei Jia, Wei Huang, Hong Zhou, Jue Liu, Xiaoyun Liu, Qiudan Sun, Xiaojia Li, Jing Bai, Fangjing Liu, Yihong Liu, Yinzi Jin, Ming Xu, on behalf of China-ASEAN Science and Technology Cooperation Center for Public Health

“…The Center held the Second Annual Forum on China-ASEAN Cooperation in Public Health on June 26–28, 2024, and the participants reached consensus on launching the China-ASEAN Beijing Declaration on Cooperation in Innovation of Health Products and Technologies, which calls on China and ASEAN countries to carry out the following actions: (1) Establish a more effective, open, and inclusive cooperation mechanism for health product innovation towards a China-ASEAN innovation ecosystem; (2) Enhance R&D capabilities by targeting new technologies, methods and appropriate and affordable health products for key populations and addressing diseases prevalent in China and ASEAN; (3) Establish a China-ASEAN Collaboration Center for Health Product Innovation, coordinate regional development plans, and enhance equitable access to pharmaceutical products at the regional level; (4) Accelerate regulatory harmonization in the region by optimizing and improving regulatory modalities of China and ASEAN Countries; and (5) Strengthen cross-sectoral cooperation to build resilient health system and achieve sustainable development of innovation cooperation. …”
Get full text

Quality assessment of spent laying hens and analysis of influencing factors by Runzhe Wang, Jiahui Lai, Guiyun Xu, Chuanwei Zheng, Zhiqiong Mao, Jiangxia Zheng

“…Surveys show that the main factor affecting the selling price of spent laying hens is body weight, and the optimal weight range is where farmers gain price advantages during the culling process. …”
Get full text

Non-Linear Biomechanical Evaluation and Comparison in the Assessment of Three Different Piece Dental Implant Systems for the Molar Region: A Finite Element Study by Jesus Alejandro Serrato-Pedrosa, Ignacio Villanueva-Fierro, Rodrigo Arturo Marquet-Rivera, Rosa Alicia Hernández-Vázquez, Salvador Cruz-Lopez, Verónica Loera-Castañeda

“…The widely available options of different manufacturers in dental implant systems have complicated the selection criteria process for periodontists, necessitating careful consideration of various factors when selecting suitable solutions for individual patient needs. Optimal implant selection requires careful consideration of the patient-specific factors, implant design, and surgical technique. …”
Get full text

Malva neglecta essential oil: A promising approach for bio-preserving mayonnaise and assessing variable correlations through principal component analysis and heat map by Amin Abbasi, Hedayat Hosseini, Hadi Pourjafar, Samaneh Moradi, Saeedeh Shojaee-Aliabadi

“…When MNEO was utilized at 5084 ppm, the oxidative stability of the specimens was also more effectively preserved at optimal levels (peroxide values of 1.76, 1.98, and 2.34 meq O2/kg of oil for TBHQ, 5084 ppm, and 2542 ppm treatments, respectively) (P < 0.05). …”
Get full text

Systematic Review and Network Meta-Analysis on Treating Hormone Receptor-Positive Metastatic Breast Cancer After CDK4/6 Inhibitors by Neha Pathak, Abhenil Mittal, Sudhir Kumar, Chitrakshi Nagpal, Eitan Amir, Partha Haldar, Bharath B. Gangadharaiah, Akash Kumar, Ashutosh Mishra, Atul Batra

“…Introduction: The optimal treatment of estrogen receptor-positive (ER +) metastatic breast cancer (MBC) after progression on cyclin-dependent 4/6 kinase inhibitors (CDK4/6i) is unknown. …”
Get full text

HSRoadNet: Hard-Swish Activation Function and Improved Squeeze&#x2013;Excitation Module Network for Road Extraction Using Satellite Remote Sensing Imagery by Xunqiang Gong, Yingjie Ma, Ailong Ma, Zhaoyang Hou, Meng Zhang, Yanfei Zhong

“…The mean intersection over union (MIoU) value of the proposed method was the suboptimum with a disparity of 0.2&#x0025; from the optimal. Ablation experiments show that the proposed method performs best in various indices, and the global accuracy, MIoU, class average accuracy, and recall rate are improved by 0.5&#x0025;, 0.1&#x0025;, 0.5&#x0025;, and 0.2&#x0025;, respectively, compared with the suboptimal method. …”
Get full text

Comprehensive evaluation of the properties of camel bone gelatin: impact of the duration of pre-treatment and extraction by Meriem Imelhayene, Abdelkader Adamou, Samira Becila, Ayad Redjeb, Dahia Saidj, Abdelhakim Senoussi, Dimitris Sarris, Eleni Naziri

“…These characteristics were predominantly influenced by the length of pre-treatment and extraction. Optimal results were obtained under moderate processing conditions. …”
Get full text

Database and geospatial mapping study of those eligible for extracorporeal cardiopulmonary resuscitation in the Thames Valley Region, England by Oscar Millerchip, Jasper Eddison, Alex Rosenberg, Jon Bailey, James Raitt

“…Geospatial analysis techniques can aid in reviewing the optimal delivery methods of ECPR and improve equitable geographical access to services. …”
Get full text

Rapid diagnosis of bacterial vaginosis using machine-learning-assisted surface-enhanced Raman spectroscopy of human vaginal fluids by Xin-Ru Wen, Jia-Wei Tang, Jie Chen, Hui-Min Chen, Muhammad Usman, Quan Yuan, Yu-Rong Tang, Yu-Dong Zhang, Hui-Jin Chen, Liang Wang

“…Multiple ML models were constructed and optimized, with the convolutional neural network (CNN) model achieving the highest prediction accuracy at 99%. …”
Get full text