Molecular mechanisms induced by phase modifiers used in hydrometallurgy: consequences on transfer efficiency and process safety by El Maangar, Asmae, Prévost, Sylvain, Dourdain, Sandrine, Zemb, Thomas

“…Liquid–liquid (L/L) extraction is a promising method for recovering rare-earth elements from electrical and electronic waste. However, an optimized process on an industrial scale has not yet been established. …”
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Effect of 5-Aminolevulinic Acid on the Quality and Volatile Metabolites of Korla Fragrant Pear Fruit by SUN Tianyu, WEN Bo, WANG Chunfeng, TIAN Jia, HAO Zhichao, LIN Yan, WEN Yue, ZHANG Feng

“…Meanwhile, comprehensive quality evaluation of pear fruit under 5-ALA treatment was carried out using principal component analysis (PCA), and the optimal 5-ALA concentration for improving the fruit quality was determined. …”
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The Prognostic Value of Peripheral Blood Inflammatory Markers in Hepatocellular Carcinoma Treated with Lenvatinib Combined with PD-1 Inhibitors by Xin Y, Liu N, Peng G, Huang X, Cao X, Zhou X

“…Yujing Xin,1 Ning Liu,2 Gang Peng,3 Xiaoyu Huang,3 Xiaojing Cao,3 Xiang Zhou3 1Department of Oncology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, 250021, People’s Republic of China; 2School of Software, Shandong University, Jinan, Shandong, 250101, People’s Republic of China; 3National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100021, People’s Republic of ChinaCorrespondence: Xiang Zhou, Email zhou.xiang@yeah.netPurpose: To investigate the prognostic value of inflammatory indexes based on peripheral blood cells in unresectable hepatocellular carcinoma (HCC) patients treated with Lenvatinib combined with PD-1 inhibitors.Methods: This study retrospectively collected baseline inflammatory indexes from HCC patients received Lenvatinib and PD-1 inhibitor-based combination therapy at the Cancer Hospital of the Chinese Academy of Medical Sciences between October 2018 and October 2021. The optimal threshold values for inflammatory indexes determined using X-tile. …”
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The role of light and vision in farmed ungulates and implications for their welfare by Julia Stuhlträger, Eberhard von Borell, Jan Langbein, Christian Nawroth, Maria Vilain Rørvang, Camille M. C. Raoult, Camille M. C. Raoult

“…In the past, animal environments have been designed primarily to optimize production output and adjusted to human needs. …”
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Effects of Different Rates of Poultry Manure and Split Applications of Urea Fertilizer on Soil Chemical Properties, Growth, and Yield of Maize by Aruna Olasekan Adekiya, Oluwaseyi Iyabo Ogunboye, Babatunde Sunday Ewulo, Adeniyi Olayanju

“….), it is necessary to investigate the best time to apply UF that will optimize soil chemical properties, growth, and yield of maize. …”
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Lenvatinib versus sorafenib as second-line therapy following progression on atezolizumab–bevacizumab in patients with unresectable hepatocellular carcinoma: a multicenter retrospec... by Jaekyung Cheon, Shigeo Shimose, Hyung-Don Kim, Takashi Niizeki, Min-Hee Ryu, Tomotake Shirono, Baek-Yeol Ryoo, Hideki Iwamoto, Changhoon Yoo

“…Abstract Purpose Atezolizumab–bevacizumab (AB) is the established first-line systemic therapy for patients with unresectable hepatocellular carcinoma (uHCC). However, the optimal second-line treatment for patients unresponsive to AB remains undefined. …”
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Construction of a Real-Scene 3D Digital Campus Using a Multi-Source Data Fusion: A Case Study of Lanzhou Jiaotong University by Rui Gao, Guanghui Yan, Yingzhi Wang, Tianfeng Yan, Ruiting Niu, Chunyang Tang

“…Real-scene 3D digital campuses are essential for improving the accuracy and effectiveness of spatial data representation, facilitating informed decision-making for university administrators, optimizing resource management, and enriching user engagement for students and faculty. …”
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Postoperative Pain and Opiate Requirement is Increased Following Second-Side Surgery Among Patients Undergoing Staged Total Knee Arthroplasty by Vivek P. Chadayammuri, MD, Shuvalaxmi D. Haselton, MS, Elizabeth Diaz, PA-C, Roger H. Emerson, MD

“…Background: Primary total knee arthroplasty (TKA) continues to grow exponentially, with a significant subset of patients requiring staged bilateral procedures. The optimal interval between staged procedures and effective strategies to minimize postoperative pain to enhance rehabilitation and mobility remain poorly understood. …”
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A Study and Comparison of the Preparation of Gadolinium Aluminate Nanoparticles Using γ-Irradiated and Unirradiated Precursors by Tehani I. Al-Muhimeed, Abdullah A. Al-Kahtani, Refaat M. Mahfouz, Mujeeb Khan, M. Rafiq H. Siddiqui

“…Notably, Gd(CH3COO)3·4H2O did not produce GdAlO3 in both solid-state and sol-gel processes even after optimizing various parameters, including the application of γ-irradiation. …”
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Integrating Metabolomics and Genomics to Uncover the Impact of Fermented Total Mixed Ration on Heifer Growth Performance Through Host-Dependent Metabolic Pathways by Zhenzhen Hu, Minyu Zuo, Shixuan Ding, Yifan Zhong, Mingyuan Xue, Huichao Zheng

“…With the increasing demand for enhancing livestock production performance and optimizing feed efficiency, this study aimed to investigate the effects of fermented total mixed ration (FTMR) containing different proportions of rice straw and sheath and leaves of <i>Zizania latifolia</i> on systemic nutrient metabolism and oxidative metabolism under host genetic regulation and on growth performance of heifers. …”
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State of the Art of CFD-DEM Coupled Modeling and Its Application in Turbulent Flow-Induced Soil Erosion by Jun Xu, Fei Wang, Ruth Abegaz

“…By delving into these aspects, the review aims to advance the understanding of fluid–soil interactions and provide insights into optimizing modeling techniques for geotechnical engineering applications. …”
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Is Topical Tranexamic Acid Effective in Reducing Hematoma and Seroma in Breast Surgery? A Systematic Review and Meta-analysis by Ammar S.A. Hashemi, MD, Sara M. Hussein, MD, Zainab H. Alshehab, Abdullah A. Al Qurashi, MD, Lucas Kreutz-Rodrigues, MD, Basel A. Sharaf, MD, DDS, FACS

“…Larger studies with standardized methodologies are required to fully establish the role of topical TXA in optimizing breast surgery outcomes.…”
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The Role of Cardiac Resynchronization Therapy in Heart Failure: A Narrative Review by Olivier Uwishema, Ece Karabulut, Dalal Sheikhah, Burhan Kantawala, Misgana Gallo, Fatima Soufan, Magda Wojtara

“…Although CRT is noted to be very efficient, some challenges like technological limitations, uncertainty regarding optimal pacing, and nonresponding patients, exist. …”
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Evaluation of the Palatal Features in Relation to Graft Harvesting in the Saudi Population by Razan Alaqeely, Sumaiah Ajlan, Faisal Alsanqar, Abdulmahsin Alaqil, Abdulaziz Almansour, Mohammad A. Aldosari

“…Data on graft dimensions and palatal measurements will enable the exact planning of soft tissue harvesting to minimize surgical risks and optimize mucogingival surgery outcomes in the Saudi population.…”
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Interface Acoustic Waves in 128° YX-LiNbO₃/SU-8/Overcoat Structures by Cinzia Caliendo, Massimiliano Benetti, Domenico Cannatà, Farouk Laidoudi, Gaetana Petrone

“…Three-dimensional finite element method analysis was performed using Comsol Multiphysics software to design an optimized multilayer configuration able to achieve an efficient guiding effect of the IAW at the LiNbO₃/overcoat interface. …”
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The association between maternal tobacco smoking during pregnancy and the risk of attention-deficit/hyperactivity disorder (ADHD) in offspring: A systematic review and meta-analysi... by Mahdi Mohammadian, Lusine G Khachatryan, Filipp V Vadiyan, Mostafa Maleki, Fatemeh Fatahian, Abdollah Mohammadian-Hafshejani

“…These findings highlight the need for prenatal care guidelines and tobacco smoking cessation programs for pregnant women to reduce ADHD risk and promote optimal neurodevelopmental outcomes. Future research should explore underlying mechanisms and potential confounders further.…”
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Comparison of Inhibitor and Substrate Selectivity between Rodent and Human Vascular Adhesion Protein-1 by Ryo Kubota, Michael J. Reid, Kuo Lee Lieu, Mark Orme, Christine Diamond, Niklas Tulberg, Susan H. Henry

“…A previous comparison of purified recombinant VAP-1 from mouse, rat, monkey, and human gene sequences predicted that rodent VAP-1 would have higher affinity for smaller hydrophilic substrates/inhibitors because of its narrower and more hydrophilic active site channel. An optimized in vitro oxidative deamination fluorescence assay with benzylamine (BA) was used to compare inhibition of five known inhibitors in recombinant mouse, rat, and human VAP-1. …”
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Diagnostic and Management Pathways for Pulmonary Carcinoid Tumours in the United Kingdom: Results from the National Lung Neuroendocrine Tumour Pathway Project by Wasat Mansoor, Stuart Ferguson, Victoria Ross, Denis Talbot

“…There is inconsistency among published guidelines for the optimal diagnostic and management pathways for patients with typical (TC) or atypical (AC) pulmonary carcinoid tumours. …”
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Solving Phosphorus Fertilization-Related Drip Irrigation Emitter Clogging by Adding Mn²⁺ by Tianyu Xu, Sanlin Bao, Qiuyue Yu, Yu Gao

“…The APP was coupled with three concentrations of Mn²⁺ (1, 2, and 3 mg/L) for drip irrigation, which could optimize the blockage problem and explore the efficacy of Mn²⁺. …”
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Application of Magnetic Aquatic Plant Biochar for Efficient Removal of Antimony from Water: Adsorption Properties and Mechanism by Luyi Nan, Yuting Zhang, Min Liu, Liangyuan Zhao, Yuxuan Zhu, Xun Zhang

“…The results demonstrated that, among the three types of aquatic plants, the magnetic biochar of Arundo donax magnetic biochar (LMBC) displayed the most superior adsorption effect on Sb. Under optimal adsorption conditions (pyrolysis temperature of 300 °C, dosage of 100 mg, pH of 8), the removal rate of Sb by LMBC exceeded 97%. …”
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