Histological Ex Vivo Evaluation of the Suitability of a 976 nm Diode Laser in Oral Soft Tissue Biopsies by Gaspare Palaia, Federico Renzi, Daniele Pergolini, Alessandro Del Vecchio, Paolo Visca, Gianluca Tenore, Umberto Romeo

“…The results showed that histological readability was optimal in all the samples. The thermal damage was negligible in all groups. …”
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Development and in vitro evaluation of biomimetic injectable hydrogels from decellularized human nerves for central nervous system regeneration by Gopal Agarwal, Kennedy Moes, Christine E. Schmidt

“…Two delipidation solvents, dichloromethane: ethanol (2:1 v/v) and n-hexane: isopropanol (3:1 v/v), were evaluated, with the former achieving optimal lipid removal and better digestion. The resulting solution was crosslinked with genipin, forming an injectable hydrogel (iHPN) that gelled within 12 min at 37 °C and exhibited mechanical stiffness of approximately 400 Pa. …”
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Anti-Tumor Necrosis Factor-α Use in Pediatric Inflammatory Bowel Disease—Reports from a Romanian Center by Roxana Matran, Andra-Mihaela Diaconu, Andreea Maria Iordache, Irina Dijmărescu, Alexandra Coroleucă, Daniela Păcurar, Cristina Becheanu

“…This study aims to evaluate and document these AEs to facilitate optimal patient selection and monitoring strategies of patients undergoing these therapies. …”
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Prognostic factors and survival outcomes in patients with salivary duct carcinoma: a retrospective cohort study by Fei Chen, Liangbo Li, Jingqiao Tao, Nenghao Jin, Liwei Wang, Liang Zhu, Bo Qiao, Lejun Xing, Bo Wei, Jingqiu Bu, Haizhong Zhang

“…These findings underscore the potential significance of incorporating hematological parameters and metastatic status into clinical decision-making to optimize risk stratification and personalized treatment strategies.…”
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Spondylolisthesis and Scoliosis Progression and Associated Revision Rates Following Bilateral Lumbar Spine Microscopic Decompression by Walter-Soon-Yaw Wong, Ashton Kai Shun Tan, Kenneth Zhi Kuan Loi, Dhivakaran Gengatharan, Craigven Hao Sheng Sim, Hao Bin Chen, Yilun Huang

“…Lumbar spine microscopic decompression (LSMD) is a common surgical procedure for decompressing neural elements. Although the optimal extent of decompression remains a critical consideration, limited evidence-based guidelines define the threshold for instrumented fusion to maintain biomechanical stability. …”
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Preparation and Physicochemical Properties of High-purity Isomaltooligosaccharides by Sequential Simulated Moving Bed Chromatography by Shenghui RUAN, Xiqun ZHENG, Xiaolan LIU, Liangyu LI

“…Further the separation conditions were optimized and the best technical parameters were as follows: feed refraction was 60% and column temperature was 65 ℃. …”
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Performance evaluation of nine reference centers and comparison of DNA extraction protocols for effective surveillance of Leishmania-infected Phlebotomine sand flies: Basis for tec... by Jorian Prudhomme, Aymeric Delabarre, Bulent Alten, Umut Berberoglu, Eduardo Berriatua, Gioia Bongiorno, José Manuel Cristovao, Maya Davidovich-Cohen, Trentina Di Muccio, Ozge Erisoz Kasap, Eleonora Fiorentino, Oscar D Kirstein, Edwin Kniha, Carla Maia, Mesut Mungan, Clara Muñoz-Hernández, Muhammed Nalçaci, Gizem Oguz Kaskan, Yusuf Ozbel, Seray Ozensoy Toz, Ricardo Parreira, Katharina Platzgummer, Ceylan Polat, José Risueño, Liora Studentsky, Gamze Varol, Julia Walochnik, Kardelen Yetişmiş, Florence Robert-Gangneux

“…This study aimed to compare different DNA extraction protocols and conduct a qPCR-based External Quality Assessment (EQA) through a multicenter study involving nine reference laboratories, with a focus on optimizing Leishmania DNA detection in sand fly.<h4>Methodology/principal findings</h4>EQA samples consisted of Leishmania infantum and L. major species, at concentrations ranging from 101 to 104 parasites/mL. …”
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Prevention of White Spot Syndrome Virus Infection on Penaeus monodon by Immersion in CEPM Extract of Avicennia sp. and Sonneratia sp. by D. Wahjuningrum, S.H. Sholeh, Sri Nuryati

“…Tingkat patogenitas WSSV relatif menurun setelah perlakuan tersebut sehingga dapat digunakan untuk merangsang kekebalan tubuh udang.  Perlakuan yang optimal yaitu pada dosis 250 ppm, dimana pada perlakuan ini dapat meningkatkan kelangsungan hidup udang uji yang diuji tantang dengan white spot syndrome virus (WSSV) dengan tingkat kelangsungan hidup 98,4 %. …”
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Image-Based Detection and Classification of Malaria Parasites and Leukocytes with Quality Assessment of Romanowsky-Stained Blood Smears by Jhonathan Sora-Cardenas, Wendy M. Fong-Amaris, Cesar A. Salazar-Centeno, Alejandro Castañeda, Oscar D. Martínez-Bernal, Daniel R. Suárez, Carol Martínez

“…Leukocyte detection employed optimal thresholding segmentation utility (OTSU) thresholding, binary masking, and erosion, followed by the connected components algorithm. …”
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Comprehensive Medical and Psychological Rehabilitation in War Trauma (clinical case) by O.A. Panchenko, A.V. Kabantseva, O.O. Zhogina, I.A. Serdyuk

“…., 65 years old, sustained a mine-blast injury (MBI) to the right upper limb extremity during shelling. The optimal restoration of the functions of the upper injured limb and the patient's health (physical, somatic, mental) was carried out according to the algorithm of comprehensive medical and psychological clinical rehabilitation. …”
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Near-infrared spectroscopy–guided personalized repetitive transcranial magnetic stimulation for bipolar depression: a case report by Chun-Hung Chang, Chun-Hung Chang, Chun-Hung Chang, Wen-Chun Liu, Po-Han Chou

“…Although our findings are promising, further randomized controlled trials are needed to validate the efficacy and safety of and determine the optimal parameters for this approach.…”
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Evaluation of treatment strategies for patients with stage IIIA non-small cell lung cancer in the immunotherapy era by Amy Alabaster, Jeffrey B. Velotta, Haley I. Tupper, Mark S. Walker, Yanina Natanzon

“…Background: Optimal treatment for patients with stage IIIA NSCLC is controversial. …”
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Barriers and Facilitators to User Engagement and Moderation for Web-Based Peer Support Among Young People: Qualitative Study Using the Behavior Change Wheel Framework by Ananya Ananya, Janina Tuuli, Rachel Perowne, Leslie Morrison Gutman

“…In particular, supporting the improvement of memory, attention, and decision-making skills of those involved; adapting the physical environment to facilitate effective interactions; and reducing negative emotions are suggested to optimize the value and effectiveness of peer support groups for young people’s mental health for both the service users and moderators of these services. …”
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Effectiveness of interventions for middle-aged and ageing population with neck pain: a systematic review and network meta-analysis protocol by Alison B Rushton, Nicola R Heneghan, Taweewat Wiangkham, Uchukarn Boonyapo, Piyameth Dilokthornsakul, Nattawan Phungwattanakul

“…Current clinical practice guidelines and systematic reviews recommended conservative, pharmacological and invasive interventions for individuals with NP. However, optimal management specifically for those who are middle-aged or older adults (≥45 years) is not available; and important considering our ageing population.Methods and analysis A systematic review with network meta-analysis (NMA) will be conducted following the Cochrane guidelines. …”
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Correlation-guided decoding strategy for low-resource Uyghur scene text recognition by Miaomiao Xu, Jiang Zhang, Lianghui Xu, Wushour Silamu, Yanbing Li

“…The role of the CGD decoder is to perform correlation calculations using the outputs from the Transformer decoder and the encoder to optimize the final recognition performance. At the same time, the CGD decoder can utilize the outputs from the Transformer decoder to provide semantic guidance for the feature extraction of the encoder, enabling the model to understand the semantic structure within the input data better. …”
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Assessing the Efficacy of Broad-Spectrum Antibiotics in Controlling Bacterial Contamination in the In Vitro Micropropagation of Ginger (Zingiber officinale Rosc) by Selam Tewelde, Subban Patharajan, Zenebe Teka, Desta Berhe Sbhatu

“…These findings are important foundations towards developing more optimized protocols of sterilizing explants and controlling bacterial contaminants for large-scale in vitro micropropagation of the Deribo ginger cultivar.…”
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The Study’s Chemical Interaction of the Sodium Silicate Solution with Extender Pigments to Investigate High Heat Resistance Silicate Coating by Cuong Manh Le, Thu-Huong Le

“…Thus, we proposed that the geopolymerization process between sodium silicate solution and extender pigments (ZnO, TiO2, Fe2O3, CaCO3, and Na2SiF6) increases when the curing time from 1 to 20 days leads to forming geopolymer silicate with high thermal stability. In addition, the optimal mixing ratio between sodium silicate solution and extender pigments (ZnO, TiO2, Fe2O3, CaCO3, and Na2SiF6) is as follows: 25% binder (sodium silicate solution), 8% ZnO; 5% TiO2, 5% Fe2O3, 1% Na2SiF6, 21% CaCO3, 34% H2O, and 1% additives to make high heat resistance silicate coating with temperature resistance at 1000°C.…”
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Specificity of psychological readiness for changes and psychological resilience in the employees of the State Criminal-Executive Service of Ukraine by O. V. Mitroshkina

“…Less pronouncedness of a number of components of psychological readiness for change and a certain deficiency of its interaction with psychological resilience can hinder both the successful professional activity of low-level group and their optimal functioning in the personality’s sense. The results obtained in the study can be used to develop programs for psychological support of the professional activities of the staff of the Criminal-Executive Service at the stage of its reformation.…”
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Assessment of RANS Models for Milli-Channel Turbulent Flow in Drip Irrigation Emitter by Qi Feng, Qingzheng Li, Yaojun Li, Xuefeng Qiu, Jiandong Wang, Xingfa Huang

“…Additionally, the magnitude of wall shear stress in the channel corners fell below the threshold required for self-cleaning, underscoring the necessity for optimizing channel structures to enhance the anti-clogging performance of the emitter.…”
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A Prospective Study Comparing Two-Time Points of Thyroid Hormone Replacement during the Holy Month of Ramadan by Zeinab Dabbous, Buthaina Alowainati, Sara Darwish, Hamda Ali, Seleena Farook, Mariam Al Malaheem, Abeir Abdalrubb, Wajiha Gul, Wajiha Abu Haliqa

“…Conclusion. Choosing an optimal time for levothyroxine intake during the month of Ramadan remains a challenge. …”
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