Contemporary Management of Patients With Chagas Cardiomyopathy in Bolivia by Evan Czulada, BS, Sascha Bercovitch, BA, Yazan Alshawkani, MD, Natalia Noya Weise, MD, Adriana E. Hernani Rodrigo, BS, Ronald Gustavo Durán Saucedo, MD, Marcelo Buhezo Chamón, MD, Robert H. Gilman, MD, David T. Martin, MD

“…Background: Chagas cardiomyopathy (CCM) is the debilitating result of a parasitic infection that causes structural and electrical abnormalities. Yet, optimal CCM management is challenging in the resource-poor communities where it predominates. …”
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Liver transplantation for homozygous familial hypercholesterolemia: a retrospective analysis from Chinese experience by Hao-Su Zhan, Lin Wei, Wei Qu, Zhi-Gui Zeng, Ying Liu, Yu-Le Tan, Jun Wang, Liang Zhang, En-Hui He, Guang-Peng Zhou, Hai-Ming Zhang, Zhi-Jun Zhu, Li-Ying Sun

“…Method To assess the clinical efficacy, prognosis, and optimal timing of LT for HoFH, a retrospective analysis was conducted on the preoperative, surgical conditions, and postoperative follow-up of children who received an LT for HoFH at the Beijing Friendship Hospital over the period from December 2014 to August 2022. …”
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Exploring the Role of the Pharmacist in the Prevention and Management of Hypertensive Disorders in Pregnancy in Ashanti Region, Ghana by Pauline Boachie‐Ansah, Berko Panyin Anto, Afia Frimpomaa Asare Marfo, Edward Tieru Dassah, Morrison Asiamah, Ivan Eduku Mozu, Nana Ofori Adomako, Kwaku Gyamfi Oppong

“…Prompt management of these disorders is usually recommended to optimize outcomes. Administration of pharmacotherapeutic agents is critical in the prevention and management of these disorders. …”
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Semaglutide and laparoscopic sleeve gastrectomy in an adolescent with congenital adrenal hyperplasia due to 21-hydroxylase: a case report by Alaina P. Vidmar, Linus Kaiser, Matthew J. Martin, Stuart Abel, Aimee G. Kim, Madeleine Weitzner, Cynthia E. Muñoz, Lynda K. Fisher, Mimi S. Kim, Kamran Samakar

“…The successful outcomes from both pharmacotherapy and bariatric surgery suggest that tailored obesity management strategies can optimize health in this unique population, reinforcing the need for further research into comprehensive obesity care in individuals with congenital adrenal hyperplasia.…”
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Effect of probiotics on the growth, blood profile, and nutritional-metabolic profile of feedlot cattle by Flavia I. Mansilla, María C. Aristimuño Ficoseco, María H. Miranda, Marcela D’Urso Villar, Graciela M. Vignolo, María E. F. Nader-Macías

“…Analysis of clinical parameters showed optimal animal body condition and sensorium state. …”
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A survey of the commercial traits and antioxidant status of goat milk in Mediterranean pastoral farms by Manuel Delgado-Pertiñez, Juan M. Mancilla-Leytón, Eduardo Morales-Jerrett, Sara Muñoz-Vallés, Verónica Cruz, Yolanda Mena

“…The negative correlation between the TAC and the somatic cell count contributes to the important role of antioxidants in maintaining optimal udder health. Vitamin A could be involved in this antioxidant mechanism due to the positive correlation between the TAC and retinol determined in a previous study. …”
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Mapping Susceptibility and Risk of Land Subsidence by Integrating InSAR and Hybrid Machine Learning Models: A Case Study in Xi'an, China by Chen Chen, Mimi Peng, Mahdi Motagh, Xinxin Guo, Mengdao Xing, Yinghui Quan

“…In this study, four machine learning models are compared to determine the optimal model, and found that the Random Forest (RF) performs the best in predicting InSAR-derived spatial deformation (Root Mean Square Error = 3.53 mm) and susceptibility (Area Under the Curve = 0.97). …”
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Transition to Virtual Care Services during COVID-19 at Canadian Pain Clinics: Survey and Future Recommendations by Victoria Borg Debono, Samuel Neumark, Norman Buckley, Ramesh Zacharias, Eleni Hapidou, Jennifer Anthonypillai, Susy Faria, Carrie-Lynn Meyer, Thomas Carter, Nadia Parker, Brenda Lau, Emmanuel Abreu, Scott Duggan, Etienne Bisson, Josie Pierre, Regina Visca, Patricia Poulin

“…This study aimed to (1) describe and compare the transition from in-person to virtual pain care services at Canadian pain clinics during the onset of the COVID-19 pandemic and (2) provide postpandemic recommendations for pain care services to optimize the quality of patient care. Materials and Methods. …”
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Microclimate monitoring in commercial tomato (Solanum Lycopersicum L.) greenhouse production and its effect on plant growth, yield and fruit quality by Jakub Šalagovič, Dorien Vanhees, Pieter Verboven, Kristof Holsteens, Bert Verlinden, Marlies Huysmans, Bram Van de Poel, Bram Van de Poel, Bart Nicolaï, Bart Nicolaï, Bart Nicolaï

“…These findings could encourage the sector to deploy larger sensor networks for optimal greenhouse climate control. A sensor grid covering the whole area of the greenhouse is a necessity for climate control strategies to mitigate suboptimal conditions.…”
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CFD Modelling of a Centrifugal Compressor with Experimental Validation through Radial Diffuser Static Pressure Measurement by Brett Dewar, Jonna Tiainen, Ahti Jaatinen-Värri, Mike Creamer, Mariana Dotcheva, Jovana Radulovic, James M. Buick

“…The simulation results were also used to investigate the effect of the position (from the blade trailing edge) of the impeller-diffuser interface (a characteristic of the frozen rotor simulation approach). Here an optimal position for the interface was found to be 2% of the blade radius. …”
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Increasing Health Burdens Driven by Global Trade Induced Air Pollution by Ruifei Li, Yu Luo, Xu Zhu, Jin Zhang, Pei Hua, Zhenyu Wang, Wenyu Yang, Qiuwen Chen, Hui Li

“…Accordingly, our findings provide profound suggestions for future policy decisions from different perspectives and demonstrate that optimizing global supply chain through cooperation would mitigate the PM2.5‐related health impacts.…”
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Body composition and physical performance of mountain bike athletes by Rayane Carvalho de Moura, Crislane de Moura Costa, Cirley Pinheiro Ferreira, Bruna Lorena Soares Cavalcante Sousa, Leandra Caline dos Santos, Michelly da Silva Pinheiro, Sérgio Luís Galan Ribeiro, Sandro Soares Almeida, Joseline Lima e Silva Pinho, Naíza Monge Lages, Maria Flávia de Sousa, Iago Alves Costa, Glêbia Alexa Cardoso, Acácio Salvador Veras Silva, Alisson Alves Silva, Jefferson Cruz dos Santos Leite, Felipe Machado Brito, Lailson Henrique Oliveira dos Santos, Rubens Lima Rodrigues, Jairo da Costa Souza, Marcos Antonio Pereira dos Santos

“…Understanding these aspects can help optimize training and maximize results. This study aimed to analyze the influence of body composition on physical performance in mountain bike athletes. …”
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A rare splice site mutation in the gene encoding glucokinase/hexokinase 4 in a patient with MODY type 2 by D. E. Ivanoshchuk, E. V. Shakhtshneider, A. K. Ovsyannikova, S. V. Mikhailova, O. D. Rymar, V. I. Oblaukhova, A. A. Yurchenko, M. I. Voevoda

“…When nonclassical diabetes mellitus is being diagnosed in young people and pregnant women, genetic testing is needed to verify the diagnosis and to select the optimal treatment method.…”
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A new process for extracting vanadium by direct calcification using the heat of molten vanadium slag by Qu J.-W., Zhang T.-A., Lv G.-Z., Chen Y.

“…When the mass ratio of Ca to V was 0.75, under the optimal acid leaching conditions (particle size of calcified vanadium slag less than 0.075 mm, leaching temperature 90 ℃, H2SO4 concentration 200 g.L-1, liquid-to-solid ratio 6:1 ml.g-1, leaching time 60 min, and stirring speed 300r.min-1), the leaching rate of vanadium from calcified vanadium slag could exceed 90%. …”
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Predicting the exposure of mycophenolic acid in children with autoimmune diseases using a limited sampling strategy: A retrospective study by Ping Zheng, Ting Pan, Ya Gao, Juan Chen, Liren Li, Yan Chen, Dandan Fang, Xuechun Li, Fei Gao, Yilei Li

“…This study aims to use machine learning and deep learning algorithms to develop a prediction model of MPA exposure for pediatric autoimmune diseases with optimizing sampling frequency. Pediatric autoimmune patients' data were collected at Nanfang Hospital between June 2018 and June 2023. …”
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Method and Experimental Research of Transmission Line Tower Grounding Body Condition Assessment Based on Multi-Parameter Time-Domain Pulsed Eddy Current Characteristic Signal Extra... by Yun Zuo, Jie Wang, Xiaoju Huang, Yuan Liu, Zhiwu Zeng, Ruiqing Xu, Yawen Chen, Kui Liu, Hongkang You, Jingang Wang

“…Four defects with different corrosion levels were classified using the optimized SVM model, with an accuracy rate of 95%. …”
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Genome-Wide Identification and In Silico Expression Analysis of <i>CCO</i> Gene Family in <i>Citrus clementina</i> (Citrus) in Response to Abiotic Stress by Sadaf Sarwar, Adnan Sami, Muhammad Zeshan Haider, Layba Tasawar, Jannat Akram, Arsalan Ahmad, Muhammad Shafiq, Haitham E. M. Zaki, Gabrijel Ondrasek, Muhammad Shafiq Shahid

“…Notably, two genes, <i>CcNCED1</i> and <i>CcNCED3</i>, were significantly expressed among the <i>CCO</i> genes, and these were found to be expressed during stress and played a crucial role in enabling optimal plant development. Furthermore, a comprehensive genome-wide comparison of <i>CCO</i> genes in <i>C. …”
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Multimodality Treatment Including Triplet Regimen as First-Line Chemotherapy May Improve Prognosis of Serum AFP-Elevated Gastric Cancer with Liver Metastasis by Yakun Wang, Lin Shen, Ming Lu, Zhi Ji, Xiaotian Zhang

“…This study sought to investigate the optimal treatment modality. A total of 319 gastric cancer patients with liver metastasis (GCLM) whose serum AFP levels were tested before treatment were enrolled in this study. …”
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Regional differences in triage decisions affect hospital mortality among frail COVID-19 patients in the COvid MEdicaTion study by Julia Minnema, Roos Sablerolles, Janneke van Kempen, Hugo van der Kuy, Harmke Polinder-Bos, Bob van de Loo, Jorie Versmissen, Miriam L. Haaksma, Melvin Lafeber, Miriam C. Faes, on behalf of the COMET research team^

“…Conclusion Our study shows that, despite variation in rates of ICU admission between northern and southern countries for frail patients, no difference in in-hospital mortality was observed. This might help optimize prioritization of resources in a pandemic setting while offering options for palliative care instead of ICU admission.…”
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Radiomics analysis of thoracic vertebral bone marrow microenvironment changes before bone metastasis of breast cancer based on chest CT by Hao-Nan Zhu, Yi-Fan Guo, YingMin Lin, Zhi-Chao Sun, Xi Zhu, YuanZhe Li

“…Multiple machine learning algorithms were utilized to construct various radiomics models for predicting the risk of bone metastasis, and the model with optimal performance was integrated with clinical features to develop a nomogram. …”
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