Impact of Organic Agriculture on the Quality of Grapes (Syrah and Tempranillo) Harvested in Guanajuato, Mexico: Relationship Between Soil Elemental Profile and Grape Bioactive Prop... by Fabio Macías-Gallardo, Tannia Alexandra Quiñones-Muñoz, Raúl Miranda-Avilés, Luis Felipe Ramírez-Santoyo, Gabriela Ana Zanor, César Ozuna

“…Finally, the edaphic conditions of the ORG vineyard allowed for one to obtain optimal grapes for winemaking due to their higher phenol content.…”
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Joint Group and Multi Institutional Position Opinion: Cirrhotic Cardiomyopathy—From Fundamentals to Applied Tactics by Ivan Rankovic, Ivana Babic, Jelena Martinov Nestorov, Jelena Bogdanovic, Maja Stojanovic, Jovanka Trifunovic, Nikola Panic, Mihailo Bezmarevic, Jelena Jevtovic, Dusan Micic, Vladimir Dedovic, Nemanja Djuricic, Filip Pilipovic, Elena Curakova Ristovska, Tijana Glisic, Sanja Kostic, Nemanja Stojkovic, Nata Joksimovic, Mileva Bascarevic, Aleksandra Bozovic, Lewis Elvin, Ajibola Onifade, Keith Siau, Elizaveta Koriakovskaia, Vladimir Milivojevic

“…However, our group still advocates them as essential tools in optimizing the neurohumoral pathologic axis that perpetuates CCM. …”
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Sequential Docetaxel in ≥7 Cycles Followed by Cabazitaxel Improves Oncological Outcomes in Patients with Metastatic Castration-Resistant Prostate Cancer by Seiichi Kato, Manabu Takai, Koji Iinuma, Shota Fujimoto, Masahiro Nakano, Takashi Ishida, Masahiro Uno, Masayoshi Tamaki, Mitsuhiro Taniguchi, Hisao Komeda, Yoshito Takahashi, Takuya Koie

“…However, it is unclear whether switching to second-line chemotherapy or optimal sequencing of cabazitaxel (CBZ) ensures better clinical outcomes. …”
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Standardization in the management of gram-negative bloodstream infections after implementation of a clinical care guideline at a large academic, safety-net institution: a quasi-exp... by Michael A. Deaney, Katherine C. Shihadeh, Alexandra Craig, Margaret M. Cooper, Paul D. Paratore, Timothy C. Jenkins

“…These findings support the effectiveness of institutional guidelines in standardizing care, optimizing resource utilization, and promoting evidence-based practices in infectious disease management. …”
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Effects of Light Intensity and Irrigation Method on Growth, Quality, and Anthocyanin Content of Red Oak Lettuce (<i>Lactuca sativa</i> var. <i>cripspa</i> L.) Cultivated in a Plant... by Thanit Ruangsangaram, Pariyanuj Chulaka, Kriengkrai Mosaleeyanon, Panita Chutimanukul, Michiko Takagaki, Na Lu

“…These changes in coloration were optimized by day 5 after treatment. Additionally, spectral indices, including normalized difference vegetation index and photochemical reflectance index, varied significantly among treatments. …”
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Characterization of the Phosphotransferase from <i>Bacillus subtilis</i> 1101 That Is Responsible for the Biotransformation of Zearalenone by Yuzhuo Wu, Qiuyu Zhou, Junqiang Hu, Yunfan Shan, Jinyue Liu, Gang Wang, Yin-Won Lee, Jianrong Shi, Jianhong Xu

“…The experiments conducted on MCF-7 cells demonstrated that ZEA-P exhibited a lower level of estrogenic toxicity than ZEA. The optimal reaction conditions for ZPH1101 were determined to be 45 °C and pH 8.0. …”
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Artificial intelligence‐based body composition analysis using computed tomography images predicts both prevalence and incidence of diabetes mellitus by Yoo Hyung Kim, Ji Won Yoon, Bon Hyang Lee, Jeong Hee Yoon, Hun Jee Choe, Tae Jung Oh, Jeong Min Lee, Young Min Cho

“…Results Visceral fat (VF) proportion and VF/subcutaneous fat (SF) ratio increased with age, and both strongly predicted the presence and risk of developing diabetes. Optimal cut‐offs for VF proportion were 24% for men and 16% for women, while VF/SF ratio values were 1.2 for men and 0.5 for women. …”
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Large-scale analysis highlights obesity as a risk factor for chronic, non-communicable inflammatory diseases by Sadegh Mousavi, Katja Bieber, Henner Zirpel, Artem Vorobyev, Henning Olbrich, Cristian Papara, Cristian Papara, David A. De Luca, David A. De Luca, Diamant Thaci, Enno Schmidt, Gabriele Riemekasten, Peter Lamprecht, Matthias Laudes, Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Ralf J. Ludwig, Ralf J. Ludwig

“…Propensity score matching optimized between-group comparability, and sensitivity analyses assessed study robustness.ResultsThe risk of developing any CID was 28.48% in overweight/obese individuals versus 17.55% in non-overweight/obese controls, with a hazard ratio (95%-confidence interval) of 1.52 (1.509-1.521, p&lt;0.0001). …”
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From bench to bedside: Developing CRISPR/Cas-based therapy for ocular diseases by Qing Zhao, Linxin Wei, Youxin Chen

“…To reach higher safety and efficiency before truly transitioning from bench to bedside, future research should concentrate on improving the specificity and efficacy of Cas proteins, optimizing delivery vectors, and broadening the applicability of therapeutic targets. …”
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Effects of Artemisia argyi leaf water extract (AWE) on growth performance, muscle quality, intestinal microbial, and metabolomics of common carp (Cyprinus carpio) by Di Sun, Nanyang Zeng, Yingjia Pan, Qingsong Shu, Jixing Zou, Yingshi Huang, Guoxia Wang, Jun Shi

“…This experiment demonstrates that AWE exerts a growth-promoting effect on common carp at an optimal concentration near 0.1 %. These findings enhance our understanding of the potential applications of AWE in aquaculture practices and provide a theoretical basis for its utilization.…”
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Prognostic Impact of the Postoperative Carcinoembryonic Antigen Level after Curative Resection of Locally Advanced Rectal Cancer by Ryoichi Tsukamoto, Kiichi Sugimoto, Yuki Ii, Takahiro Irie, Megumi Kawaguchi, Aya Kobari, Yuki Tsuchiya, Kumpei Honjo, Masaya Kawai, Shun Ishiyama, Makoto Takahashi, Kazuhiro Sakamoto

“…Objectives: This study was conducted to investigate whether preoperative or postoperative carcinoembryonic antigen (CEA) with a new cut-off value is more optimal for predicting long-term outcomes in patients with Stage II/III rectal cancer, and to investigate the effectiveness of postoperative adjuvant chemotherapy (POAC) based on the CEA values. …”
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Geodynamics of basins above subducted slabs: An integrated modelling study of tectonics, sedimentation, and magmatism in the Timok Magmatic Complex by Stojadinović Uroš, Toljić Marinko, Trivić Branislav, Pantović Radoje, Srećković-Batoćanin Danica, Krstekanić Nemanja, Kostić Bojan, Velojić Miloš, Stefanović Jelena, Ranđelović Nikola, Maleš Maja

“…Among the many examples observed worldwide, the Timok Magmatic Complex (TMC) in Serbia represents an optimal natural laboratory due to the complex tectonic setting during the various stages of the Middle Jurassic–Paleogene evolution of the subduction system. …”
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Effect of the High-FODMAP Diet on Bowel Preparation for Colonoscopy: A Multicenter, Prospective Cohort Study by Peng Cheng, Ruijun Ma, Shuling Wang, Jun Fang, Zhengrong Zhong, Yu Bai, Xiangjun Meng, Zhaoshen Li

“…Background. Optimal bowel preparation for colonoscopy is fundamental to a successful examination. …”
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3D Point Cloud from Millimeter-wave Radar for Human Action Recognition: Dataset and Method by Biao JIN, Kangsheng SUN, Hao WU, Zixuan LI, Zhenkai ZHANG, Yan CAI, Rongmin LI, Xiangqun ZHANG, Genyuan DU

“…Extensive experiments reveal that the PETer network achieves exceptional recognition rates of 98.77% on the TI dataset and 99.51% on the Vayyar dataset, outperforming the traditional optimal baseline model by approximately 5%. With a compact model size of only 1.09 MB, PETer is well-suited for deployment on edge devices, providing an efficient solution for real-time human action recognition in resource-constrained environments.…”
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Impact of Systolic Blood Pressure Trajectories and Variability on Unexplained Early Neurological Deterioration Post‐Endovascular Treatment in Acute Ischemic Stroke Patients by Xuxuan Gao, Qiheng Wu, Yu Ma, Yueran Ren, Jiaying Chen, Xiaofei Lin, Lianghao Ye, Wei Song, Jiajia Zhu, Jia Yin

“…Therefore, comprehensive post‐EVT blood pressure management should address both absolute BP levels and BPV, with particular emphasis on nighttime monitoring, to optimize early neurological recovery.…”
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Comparative Agreement Analysis of Differences in 1,5-Anhydroglucitol, Glycated Albumin, and Glycated Hemoglobin A1c Levels between Fasting and Postprandial States in Steamed Bread... by Hang Su, Yufei Wang, Xiaojing Ma, Xingxing He, Lingwen Ying, Junling Tang, Lu Dong, Yuqian Bao, Jian Zhou, Weiping Jia

“…Agreement analyses indicated good stability of 1,5-AG, GA, and HbA1c levels after the SBMT. HbA1c had an optimal stability, which was superior to that of GA or 1,5-AG.…”
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Influence of TMPRSS6 genotype on iron status parameters in stable COPD patients by Trtica Marko, Novaković Ivana, Dopsaj Violeta, Milenković Branislava, Janković Jelena, Dimić-Janjić Sanja, Dopuđa-Pantić Vesna, Martinović Jelena, Jovičić Snežana

“…The area under the curve for erythropoietin was 0.688 (95% CI: 0.545-0.830, p=0.015), with an optimal cut-off of 9.74, sensitivity of 61.2% (95% CI: 58.1-64.3) and specificity of 65.0% (95% CI: 61.8-68.3).Conclusions: Iron status parameters do not differ between WT and HH groups of stable COPD patients. …”
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Assessing the Applicability of Photocatalytic-Concrete Blocks in Reducing the Concentration of Ambient NO2 of Chandigarh, India, Using Box–Behnken Response Surface Design Technique... by Neeru Singla, Sandeep Singla, Parteek Singh Thind, Sandeep Singh, Jasgurpreet Singh Chohan, Raman Kumar, Shubham Sharma, Somnath Chattopadhyaya, Shashi Prakash Dwivedi, Ambuj Saxena, Alibek Issakhov, Nima Khalilpoor

“…Further, the process parameters, namely, concentration of TiO2 (1 to 5 g), UV-A irradiance (1 to 5 mW/cm2), and relative humidity (RH) (10 to 70%), were optimized to achieve maximum degradation of NO2. Outcomes of batch experiments depicted that the maximum degradation of NO2, that is, 68.32%, was attained at 3.35 g of TiO2, 5 mW/cm2 of UV-A irradiance, and 64.60% RH. …”
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Telemedicine in home enteral nutrition: a structured survey exploring acceptability, preferences and experiences among patients by Ya Ma, Xuemei Li, Qian You, Wen Hu, Zhiyong Rao, Yanru Deng, Yiyao Zhang, Lei Shi

“…Conclusions HENST is a economic beneficial visit model, with high satisfaction. We should optimize and promote existing video call function of this platform to meet the demands of face-to-face communication. …”
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Thermal Development, Mortality, and Fertility of an Apulian Strain of <i>Drosophila suzukii</i> at Different Temperatures by Nuray Baser, Luca Rossini, Gianfranco Anfora, Kürşat Mustafa Temel, Stefania Gualano, Emanuele Garone, Franco Santoro

“…The species successfully developed from egg to adult at 13–29 °C, while between 6–9 and 29–33 °C the development was limited to L2/L3 stages. Optimal temperatures are around 26–28 °C, depending on the life stage. …”
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