Determinants of nosocomial infections and emerging antibiotic resistance in the Intensive Care Unit: A prospective evidence-based study by Pranali Patil, Amol Muthal, Jignesh Shah, Asavari Raut

“…Conclusions: This study highlights the high incidence rate of ventilator-associated pneumonia, with extensive drug resistance in ICU patients, highlighting the need for an optimized antimicrobial stewardship program to develop effective strategies for the management of nosocomial infections. …”
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The Effectiveness of Chitosan to Increase Body Resistance of Sangkuriang Catfish (Clarias gariepinus) Against Aeromonas hydrophila Attack by Mahatma Kresnha Radityo, Rosidah, Walim Lili, Roffi Grandiosa Herman

“… This research aims to determine the optimal dose of chitosan that is appropriate to be given to commercial feed in increasing the immune system of sangkuriang catfish fry. …”
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Efficient removal of lead (II) from paint factory wastewater using Noug stalk activated carbon: A sustainable adsorption approach by Getasew Yirdaw

“…This study aimed to evaluate the efficiency of Noug stalk activated carbon in removing lead (II) from paint factory effluent under optimized conditions. Laboratory experiments were conducted to assess the performance of Noug stalk activated carbon in treating wastewater from a paint factory. …”
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Synthesis of a Cationic Polyacrylamide under UV Initiation and Its Flocculation in Estrone Removal by Jiaoxia Sun, Xiqin Ma, Xiang Li, Jianxin Fan, Qingkong Chen, Xuelian Liu, Jin Pan

“…Besides, with the introduction of hydrophobic groups (phenyl group), an irregular and porous surface morphology and a favorable thermal stability of the PADA were observed by SEM and TG/DSC analyses, respectively. At the optimal condition (pH = 7, flocculant dosage = 4.0 mg/L and E1 concentration = 0.75 mg/L), an excellent E1 flocculation performance (E1 removal rate: 90.1%, floc size: 18.3 μm, and flocculation kinetics: 22.69×10-4 s−1) was acquired by using the efficient flocculant PADA-3 (cationic degree = 40%, and intrinsic viscosity = 6.30 dL·g−1). …”
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Study on Mg segregation, microstructure evolution and fracture behavior of hot-press sintered (TiC+B4C)/6061Al composites after T4 heat treatment by Zhaosong Liu, Zongan Luo, Xin Zhang, Yingying Feng, Jinsong Yang

“…With the increase of solution temperature, the recrystallization volume fraction of the aluminum matrix in T4 (TiC + B4C)/6061Al composites first increased and then decreased slightly, the hardness and strength of T4 (TiC + B4C)/6061Al composites increased gradually, the plasticity first increased and then decreased. An optimal balance between strength and plasticity in T4 (TiC + B4C)/6061Al composites can be achieved at the solution temperature of 530 °C.…”
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Delving into discrepancies, a single-center experience with Accelerate Pheno for gram-negative bacteremia, a rapid phenotypic susceptibility testing method by Zoe Freeman Weiss, Dimitar Zelenkov, Jon Englert, Maureen Campion

“…Stewardship programs may choose to optimize their rapid antibiotic susceptibility testing reporting to help minimize confusion and guide appropriate antibiotic selection. …”
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A literature review on transformative impacts of blockchain technology on manufacturing management and industrial engineering practices by Dharmendra Hariyani, Poonam Hariyani, Sanjeev Mishra, Milind Kumar Sharma

“…Key findings reveal its effectiveness in improving data security, risk management, and intellectual property protection, alongside optimizing inventory control and customer satisfaction. …”
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Adaptation of Higher Medical Education to the Conditions of Digitalization of Healthcare by V. A. Lazarenko, P. V. Kalutskiy, N. B. Dremova, A. I. Ovod

“…The provision is based on the use of methods such as content analysis of modern publications on the problem, their logical analysis, generalization and systemization of published information, as well as the presentation of the experience of digitalization in the higher medical education.The article shows the relevance of digitalization for health care, with which it is possible to optimize the tasks of managing the quality and accessibility of medical care. …”
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Nilai Diagnostik Ultrasonografi Hepatobilier sebagai Prediktor Atresiabilier pada Kolestasis Bayi di RSUP Sanglah Denpasar Tahun 2017 - 2021 by Kristin Agustina, Pande Putu Yuli Anandasari, Firman Parulian Sitanggang, I Wayan Gede Artawan Eka Putra, Made Widhi Asih, Putu Patriawan

“…Diagnostic tests to determine the optimal cut-off score, sensitivity, specificity, positive predictive value, negative predictive value and accuracy. …”
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The Addition of ROTEM Parameter Did Not Significantly Improve the Massive Transfusion Prediction in Severe Trauma Patients by Dongyup Baik, Seok-Ran Yeom, Sung-Wook Park, Youngmo Cho, Wook Tae Yang, Hoon Kwon, Jae Il Lee, Jun-Kyeung Ko, Hyuk Jin Choi, Up Huh, Tae Sik Goh, Chan-Hee Song, Lee Hwangbo, Il Jae Wang

“…Rotational thrombelastometry (ROTEM) has been used to evaluate the coagulation state, predict transfusion, and optimize hemostatic management in trauma patients. …”
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Integration of fly ash and ground granulated blast furnace slag into palm oil fuel ash based geopolymer concrete: a review by Ying Yi Tan, Hanizam Awang, Noor Haida Mohd Kaus

“…Further study is required to optimize the composition of POFA, FA and GGBS in the mix, and researching new, cost-effective alkaline activators obtained from waste products offers another avenue for boosting the efficiency of geopolymer synthesis.…”

Experimental and Numerical Investigation on Infilled Vertical Well LASER-Assisted SAGD by Ding Chao, Wu Yongbin, Yang Guo, Luo Chihui

“…The solvent formula was optimized, and its key mechanism was studied by viscosity reduction experiments, multicomponent phase behavior experiments at high temperature and high pressure, and scaled two-dimensional physical experiments. …”
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Clinical Management and Surgical Outcomes of Wandering Spleen with Splenic Torsion in Pediatric Patients: A Case Report by Shaban Memeti, Saimir Kuci, Toni Ristevski, Lazar Todorovic, Marijan Kamilovski, Blagica Krsteska, Haris Sulejmani

“…We emphasize the importance of timely diagnosis and appropriate management to optimize patient outcomes. Conclusion: Early detection and prompt intervention are crucial in preventing severe complications in pediatric patients. …”
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Cross-Regional Capacity Mechanism for Emergency Power Support in Extreme Weather Events by WU Zifeng, YUAN Jiahai, ZHANG Jian, ZHANG Haonan

“…Finally，targeted recommendations for optimizing capacity mechanisms are presented.…”
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Hybrid Method for Point Cloud Classification by Abdurrahman Hazer, Remzi Yildirim

“…By processing local and global features in parallel, the Hybrid ResPOL method combines these features and feeds them into the classification head, optimizing performance. Experimental results indicate that the Hybrid ResPOL method achieves an overall accuracy (OA) of 94.3% and a mean accuracy (mAcc) of 91.3% on the ModelNet40 dataset. …”
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CRISPR/Cas genome editing for cotton precision breeding: mechanisms, advances, and prospects by Vijay Sheri, Harikrishnan Mohan, Phanikanth Jogam, Anshu Alok, Gulab Khan Rohela, Baohong Zhang

“…To ensure specificity and avoiding off-target effects, we need to optimize various parameters such as target site, guide RNA design, and choosing right Cas variants. …”
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A Quantitative Examination and Comparison of the Ability of Australian Gentamicin Dosing Guidelines to Achieve Target Therapeutic Concentrations in Neonates by Luke E. Grzeskowiak, Sheree Wynne, Michael J. Stark

“…Further research to define optimal pharmacodynamic targets in neonates with respect to clinical outcomes are also urgently warranted.…”
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VA physicians intent to leave and correlations to drivers of burnout: a cross-sectional study by Robert C. Oh, David C. Mohr, Tamara M. Schult

“…Understanding physicians’ intent to leave the organization will inform efforts on optimizing the physician workforce. In this study, we examine the association of burnout and specific drivers of burnout on turnover intentions. …”
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The road ahead: emerging therapies for primary IgA nephropathy by Edward J. Filippone, Rakesh Gulati, John L. Farber

“…Our current approach for those requiring immunosuppression involves combining the reduction of Gd-IgA1 (nefecon) with suppressing the effects of inflammation (iptacopan). The optimal duration of such therapy is uncertain. Clearly, there is more to be learned with many trials underway.…”
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Leveraging mRNA technology for antigen based immuno-oncology therapies by Wei Zheng, Michele Ceccarelli, Charalampos S Floudas, Siranush Sarkizova

“…This comprehensive overview highlights the therapeutic potential of mRNA-based cancer vaccines and underscores ongoing research efforts aimed at optimizing these therapies for improved clinical outcomes.…”
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