Daratumumab for autoimmune diseases: a systematic review by Martin Krusche, Ina Kötter, Lennard Ostendorf, Nikolas Ruffer, Marie-Therese Holzer, Tobias B. Huber

“…Adverse events were reported in 45% of patients including application-associated reaction (20%), infection (19%) and hypogammaglobulinaemia (33%).Conclusion Targeting CD38 via daratumumab is a new promising therapeutic option in therapy refractory autoimmune diseases. Efficacy as well as optimal therapeutic regimen and management or prevention of adverse events require further investigation. …”
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Effects of Homogeneous Doping on Electron–Phonon Coupling in SrTiO₃ by Minwoo Park, Suk Bum Chung

“…In spite of the strong implications these reports have on specifying the pairing glue, they have not proved sufficient in explaining the magnitude of the optimal doping. This motivated us to apply density functional theory to Nb-doped STO to analyze how the phonon band structures and the electron–phonon coupling evolve with doping. …”
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Effectiveness of post-harvest treatments for Manzanilla table olives and the suitability of Hojiblanca as a substitute for mechanical harvesting by Paz Shemesh, Arnon Dag, Nizar Abd Elhadi, Reza Ehsani, Louise Ferguson, Ayelet Fishman

“…This study highlights the importance of PHFT and cultivar selection in optimizing quality and consumer satisfaction in mechanically harvested table olive production.…”
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Validity and Reliability of Dynamic and Functional Balance Tests in People Aged 19-54: A Systematic Review by Kim J Lesch, Sanni Tuomisto, Heikki O Tikkanen, Mika Venojärvi

“…This review equips healthcare professionals with valuable insights into optimal balance assessment methods for the healthy, 19 to 54 aged population…”
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Effect of Active MgO on Compensated Drying Shrinkage and Mechanical Properties of Alkali-Activated Fly Ash–Slag Materials by Hongqiang Ma, Shiru Li, Zelong Lei, Jialong Wu, Xinhua Yuan, Xiaoyan Niu

“…The results of this study provide an important theoretical basis and data support for the optimal application of MgO in AAMs. MgO expansion agents have great application potential in low-carbon buildings and durable materials. …”
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Development of a New Malnutrition Screening Tool for Patients: Human Key Tool of Nutrition by Kotono Oishi, MSc, Arisa Inoue-Hamano, PhD, Yasuhiro Hamada, MD,PhD

“…Therefore, early diagnosis and intervention of malnutrition are recommended. However, the optimal nutrition screening tool for diagnosing malnutrition remains undetermined. …”
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A Dynamic Design Methodology for Large-Scale Complex Nonlinear Systems Based on Orthogonal Decomposition Technique by Qi-Bin Wang, Si-Yang Piao, Ming-Wei Piao, Peng Dang, Qiu-Ze Li, Jing-Ying Ren

“…On the premise of meeting the requirements of crossing over different speed grade dedicated lines and realizing the running operations on three-speed levels of 160/250/350 km/h, the self-adaptive higher-/high-speed bogies can conditionally satisfy the economic reprofiling requirements of wheelsets through the optimal routing planning.…”
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Evaluating the predictive potential of RSM and ANN models in treatment of greywater-syrup mixture using Ekowe clay-PEM microbial fuel cell by Livinus A. Obasi, Cornelius O. Nevo

“…The response variables (power density generation (mW/m2) and chemical oxygen demand (COD) removal efficiency (%)) were measured against four process input variables: mass of the clay component of the proton exchange membrane (PEM) (g), PEM preparation temperature (PPT), anolyte pH, and concentration. Optimal responses with respect to power density and COD removal of 88.3 mW/m2 and 95.2% were recorded at the values of 70 g, 300°C, 8.5, and 66.9 v/v for mass of clay, PPT, pH, and anolyte concentration, respectively. …”
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Effect of Broken Coffee Beans Particle Size, Roasting Temperature, and Roasting Time on Quality of Coffee Beverage by Ezana Getaneh, Solomon Workneh Fanta, Neela Satheesh

“…However, certain problems exist in the coffee roasting process such as partial charring, over roasting, and poor temperature distribution across the coffee bean (due to the low thermal conductivity of bean), if conditions are not optimized. Hence, uniform temperature distribution across the coffee bean in the roasting process is highly desirable. …”
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Recognition and Management of Postpartum Hemorrhage by Tasabih Ali EL Hassan Mohamed, Edwin Chandraharan, Yang Pan

“…Additionally, they must respond swiftly if PPH occurs and ensure a multidisciplinary, multilayered approach for a synchronized response to optimize outcomes. This review article emphasizes the etiopathogenesis, diagnosis, and management of PPH based on current scientific evidence as well as international best practice recommendations.…”
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Nitrogen, Phosphorus, and Potassium Requirements to Improve <i>Portulaca oleracea</i> L. Growth, Nutrient and Water Use Efficiency in Hydroponics by Antonios Chrysargyris, Nikolaos Tzortzakis

“…The N200_PKinc NS resulted in improved crop growth compared to N200_PKrec NS, suggesting a positive correlation between optimal N levels (i.e., 200 mg L⁻¹) and increased P and K levels (105 and 525 mg L⁻¹, respectively). …”
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Cloning, expression analysis, and the photoperiodic response of CHH gene in Panulirus homarus by Zhimin Ju, Jiajun Luo, Charles Brighton Ndandala, Chongqing Wen, Zhao Yanfei, Huafang Liang

“…The photoperiod experiment results showed that ovarian development was optimal at 14 L:10D, and the expression levels of PhCHH-A and PhCHH-B in the eyestalk increased to the peak. …”
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Determining Planetary Boundary Layer Height by Micro-pulse Lidar with Validation by UAV Measurements by Yueh-Chen Wang, Sheng-Hsiang Wang, Jasper R. Lewis, Shuenn-Chin Chang, Stephen M. Griffith

“…Furthermore, the Haar wavelet and the Hybrid image processing can detect the PBL development comparably well, but both methods are dependent on their initial conditions and optimized algorithm settings. In addition, the accompanying UAV observations are conclusively shown to have a high degree of efficacy for validating the lidar data. …”
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Determination of Capsaicin and Dihydrocapsaicin in Some Chilli Varieties using Accelerated Solvent Extraction Associated with Solid-Phase Extraction Methods and RP-HPLC-Fluorescenc... by Saksit Chanthai, Jureerat Juangsamoot, Chalerm Ruangviriyachai, Suchila Techawongstien

“…The method recoveries of real samples were found to be 60.7-98.6%. The optimized extraction method were applied for the determination of the two capsaicinoids in ten vareities of hot chilli pepper samples. …”
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Investigation of Chitosan-Based Hydrogels and Polycaprolactone-Based Electrospun Fibers as Wound Dressing Materials Based on Mechanical, Physical, and Chemical Characterization by Barkin Aydin, Nihat Arol, Nimet Burak, Aybala Usta, Muhammet Ceylan

“…These findings highlight the optimal combinations of nanofibrous mats and hydrogels, offering guidance for future wound dressing designs that balance mechanical strength, water absorption, and antimicrobial properties. …”
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Automatic monitoring of treated water released from wastewater treatment plants using model-based clustering with density estimation by Sheik Faritha Begum, K Lokeshwaran

“…Unlike standard clustering algorithms like K-means, hierarchical that produce optimized clusters in statistical terms that deviate from naturally categorized clusters, model-based clustering with density estimation operates on the assumption that each data object originates from the mixture of underlying probability distributions. …”
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Treatment of Brachial Plexus Injuries following Gunshot Injuries: A Systematic Review by Rohun Gupta, Isabel Herzog, Lauren Phung, Jacquelyn Roth, Joseph Weisberger, Margaret Luthringer, Edward S. Lee, Ashley Ignatiuk

“…Several patients suffered from complications, with neuroma being the most common long-term complication that required reoperation. Conclusion. The optimal timing for surgeries involving BPIs should be determined after examining the level of nerve damage, associated injuries, operative risks, and electrophysiological workup for indications of spontaneous regeneration. …”
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Accurate inversion of chlorophyll content based on PROSPECT-LSROGF-BAS-BP method by Shengfan Zhu, Jin Zhang, Dan Wang, Rui Ding

“…Next, to improve the retrieval accuracy of traditional BP neural networks for chlorophyll content, the Beetle Antennae Search (BAS) algorithm is used to optimize the weights and thresholds of the BP neural network, forming the BAS-BP model. …”
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Navigating the future: unveiling new facets of nurse work engagement by Yini Zhang, Ruolin Qiu, Yuezhong Wang, Zhihong Ye

“…Regression analysis indicated that structural empowerment (support, resources, opportunity, and information) and psychological capital (optimism, resilience, self-efficacy, and hope) were significant positive predictors of work engagement (p < 0.01), jointly accounting for 69% of its variance. …”
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A Method for Tomato Ripeness Recognition and Detection Based on an Improved YOLOv8 Model by Zhanshuo Yang, Yaxian Li, Qiyu Han, Haoming Wang, Chunjiang Li, Zhandong Wu

“…Additionally, the BiFPN (Bidirectional Feature Pyramid Network) module is introduced to replace the traditional PANet connection, which achieves efficient feature fusion across different scales of tomato skin color, size, and surrounding environment and optimizes the expression ability of the feature map. …”
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