A pooled analysis of the side effects of non-invasive Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) by Manon Giraudier, Carlos Ventura-Bort, Christoph Szeska, Mathias Weymar, Mathias Weymar

“…Interval stimulation notably reduced the likelihood of some side effects, particularly for neck pain, dizziness and unpleasant feelings, suggesting potential for optimizing taVNS protocols. Stimulation intensity and duration showed few statistically significant, but clinically minimal (i.e., very small) effects.ConclusionOverall, these findings demonstrate a favorable safety profile of taVNS, with mostly mild and transient effects, supporting its use as a suitable non-invasive tool in both research and clinical applications.…”
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Three-Level SOC Equalization Control Strategy for MMC-BESS Based on Feedforward Sliding Window Integral Method by Yuan Cheng, Hui Zhang, Xiaohui Wei, Wenquan Shao

“…Under the same operating conditions, compared with the traditional optimal one-third average method, the SOC equalization correction control strategy proposed in this paper has smaller submodule capacitor voltage fluctuation rate, harmonic distortion rate, and three-phase system circulating current. …”
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Program for Providing Iron Tablets in Schools and Reducing the Incidence of Anemia among Adolescent Girls in Padang City by Rita Asriyanti, Azrimaidaliza Azrimaidaliza, Frima Elda, Khiky Dwinatrana

“…Results: The iron tablets program hasn’t been optimally implemented. The study found 28.1% of adolescent girls were anemic. …”
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A novel hybrid CLARA and fuzzy time series Markov chain model for predicting air pollution in Jakarta by Nurtiti Sunusi, Ankaz As Sikib, Sumanta Pasari

“…. • The number of fuzzy time series partitions is optimally determined based on clustering results obtained through the gap statistic approach, ensuring robust partitioning. • The forecasting accuracy of the CLARA-FTSMC hybrid method, evaluated using MAE and RMSE, showed excellent performance in predicting daily air pollution levels of SO₂ and CO in Jakarta.…”
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The Innovative Design of Deep In Situ Pressure Retained Coring Based on Magnetic Field Trigger Controller by Guikang Liu, Mingzhong Gao, Zhiwen Yang, Ling Chen, Maoquan Fu, Heping Xie

“…The results show that a complex magnetization combination can weaken the nonlinear negative correlation between the magnetic force and distance. The optimal design of the valve seat magnetic circuit is Scheme 9, with the valve seat consisting of four shape identical tile magnets. …”
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Chitosan-Based Polyion Multilayer Coating on NPK Fertilizer as Controlled Released Fertilizer by Yuni Kusumastuti, Alit Istiani, Rochmadi, Chandra Wahyu Purnomo

“…On the other hand, the modification of the arrangement of chitosan-alginate layers showed that the fertilizer with the alternating layer arrangement (CA)5 was able to optimally increase the compressive strength. The mathematical model for the nitrogen release of coated fertilizer is also prepared and simulated with the MATLAB software. …”
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Purification and characterization of lipase from Bacillus subtilis kubt4 for biodiesel production by Parveen Nadaf, Shridhar Ghagane, Rubeen Dadakalandar Nadaf, Shivasharana Chandrabanda Timmappa

“…The characterized lipase exhibited alkaline properties, displaying optimal activity and stability at pH 8.0 and a temperature of 35 °C. …”
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Exploring the Potential of <i>Candida</i> sp. SW4-6 as a Probiotic for Enhancing Water Quality in Aquaculture by Jie-Ying Li, Chun-Hung Liu

“…SW4-6 emerges as a promising probiotic candidate for aquaculture water quality management due to its efficient nitrite-N and ammonia-N reduction capabilities under optimal conditions. Its virulence profile and ability to thrive across various salinity and temperature conditions further support its potential applicability in aquaculture.…”
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Modification of activated carbon prepared from black liquor with the copper ion and its application to adsorption phenol by Amir Mohammadpour, Ahmad Hallajisani, Mohammad Azadfallah, Yahya Hamzeh

“…Based on the results, it was found that AC/Cu shows the highest adsorption rate after coming in contact with phenol solution with a concentration of 100 ppm for one hour at an optimal pH of 8. The adsorption of phenol by AC/Cu is consistent with the pseudo-second-order kinetic model. …”
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Monitoring Interannual Variability in Spatial Distribution of Plastic-Mulched Farmland in Black Soil Areas Using Google Earth Engine by Jingfa Zhong, Dongmei Ji, Lei Chang, Yuefen Li

“…The key features and combinations were optimized, and then the MRFPS algorithm was used to minimize the impact of cloud contamination and map the distribution of PMF. …”
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Ensemble modeling of the climate-energy nexus for renewable energy generation across multiple US states by Joy Adul, Rohini Kumar, Renee Obringer

“…We analyze data from four key states: California, New York, Florida, and Georgia, and focus on three critical renewable energy sources: hydroelectric, solar, and wind power. To determine the optimal model, we test six primary machine learning techniques, as well as an ensemble and a mean-only baseline. …”
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Soil nutrients, microbial biomass, and crop response to organic amendments in rice cropping system in the Shiwaliks of Indian Himalayas by Richa Rajput, Priya Pokhriya, Pooja Panwar, A. Arunachalam, Kusum Arunachalam

“…Recycled waste of rice–wheat agrosystem is utilized to determine optimal sustainable solution for hilly areas. Methods Randomly blocked design experiment was conducted with rice plants, each amended with organic inputs including rice straw residue (T1), rice biochar (T2), rice compost (T3), wheat straw residue (T4), wheat biochar (T5), wheat compost (T6), mix of wheat + rice compost (T7), green manure (T8) and control (no amendment). …”
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Simulation of Flax Threshing Process by Different Forms of Threshing Drums in Combined Harvesting by Ruijie Shi, Leilei Chang, Wuyun Zhao, Fei Dai, Zhenwei Liang

“…These findings indicate that the T₂ model has a higher potential for flax harvesting in hilly and mountainous regions, especially in improving threshing efficiency and operational stability, providing an important theoretical basis for optimizing threshing equipment design.…”
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Genetics of aging and longevity by A. A. Moskalev, E. N. Proshkina, A. A. Belyi, I. A. Solovyev

“…The disclosure of the genetic structure of longevity is a fundamental problem of the evolution of ontogeny, evolutionary genetics and molecular gerontology. Under optimal conditions, the lifespan is determined by the aging rate. …”
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Family Support and Its Association with Glycemic Control in Adolescents with Type 1 Diabetes Mellitus in Riyadh, Saudi Arabia by Adwa M. AlHaidar, Norah A. AlShehri, Munira A. AlHussaini

“…Their supportive behaviors are perceived by their family members diagnosed with T1DM, but there has been no optimal association with disease control. However, the involvement of the family can aid in decreasing possible complications of the disease by intervening in critical situations.…”
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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…Finally, in silico cloning was performed using the expression vector pET28a (+) with optimized restriction sites to develop a viable strategy for large-scale production of the chosen vaccine constructs. …”
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The Impact of Locoregional Therapy in Nonmetastatic Inflammatory Breast Cancer: A Population-Based Study by Mahvish Muzaffar, Helen M. Johnson, Nasreen A. Vohra, Darla Liles, Jan H. Wong

“…Cox proportional hazards model showed that total mastectomy (HR 0.75, 95% CI 0.65–0.85) and radiation (HR 0.64, 95% CI 0.61–0.69) were associated with improved survival. Conclusions. Optimal locoregional therapy for women with nonmetastatic IBC continues to be mastectomy and radiation therapy. …”
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How does planting structure change affect the agricultural net carbon sink? Evidence from the Jiangsu coastal economic Belt by Xiaomei Shen, Rong Yan, Mingdong Jiang

“…Based on the above research, we propose implications for using resource endowments, adjusting crop planting structure, and optimizing land use.…”
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The damage evolution law and life prediction of mortar under Freeze-thaw cycles and sulfate corrosion based on entropy weight method by Yizheng Jiang, Yuang Cui, Yi Song, Xuepeng Zhang

“…The research findings indicate that silica fume significantly enhances the sulfate resistance and freeze-thaw durability of mortar materials, with an optimal dosage of 10 %. Within the scope of this study, higher silica fume content results in a greater number of sulfate attack-freeze-thaw cycles the mortar can endure before damage and failure, thereby extending its service life. …”
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Real-world assessment to estimate multiple attributes related to treatment cost driver for mantle cell lymphoma in Japan by econometric modeling by Saaya Tsutsué, Shinichi Makita, Hiroya Asou, Anila Mathew, Yuki Kado, Koki Idehara, Seok-Won Kim, Dilinuer Ainiwaer

“…This real-world study delivers insights for optimizing MCL care in Japan.…”
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