Towards a Rational Design of an Asymptomatic Clinical Herpes Vaccine: The Old, the New, and the Unknown by Aziz Alami Chentoufi, Elizabeth Kritzer, David M. Yu, Anthony B. Nesburn, Lbachir BenMohamed

“…Here we provide a brief overview of past clinical vaccine trials, outline current progress towards developing a new generation “asymptomatic” clinical herpes vaccines, and discuss future mucosal “asymptomatic” prime-boost vaccines that could optimize local protective immunity.…”
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Study on the Adhesion Properties of Raw Coal and Adhesive Clogging Characteristics of Underground Coal Bunkers by Chongyang Jiang, Lianguo Wang, Zhiyuan Pan, Jiaxing Guo, Shuai Wang

“…The findings offer significant insights for optimizing solutions to the adhesive clogging issues in underground coal bunkers and ensuring their safe and efficient operation.…”
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Classification of Strawberry Maturity Stages and Varieties Using Neural Networks Based on Volatile Organic Compounds by Jing Huang, Xuenan Zhang, Hang Yang, Zhenbiao Li, Zhengfang Xue, Qingqing Wang, Xinyuan Zhang, Shenghua Ding, Zisheng Luo, Yanqun Xu

“…Feature importance analysis indicated that the NN model exhibited the most balanced reliance on various VOCs, contributing to its optimal performance with the broad-spectrum VOC detection method, GC-IMS. …”
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Fecal Microbiota Transplantation: A Systematic Review of Therapeutic Potential, Preparation Techniques, and Delivery Methods Across Medical Conditions by Syamand Ahmed Qadir, Qausar Hamed ALKaisy, Abdulbasit F. Hasan, Farhang Hameed Awlqadr, Ammar B. Altemimi, Aryan Mahmood Faraj, Angelo Maria Giuffrè, Mohammed N. Saeed, Sherzad Rasul Abdalla

“…However, further research is essential to establish optimized procedures, standardized guidelines, and long-term safety data to facilitate its integration into mainstream medical practice. …”
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Impact of heat stress on growth and physiological parameters of soybean varieties at the seedling stage by Bashir Hassan, Samanhudi, Parjanto, Setyawati Andriyana, Komariah, Senge Masateru, Rahayu Muji, Salma Fathin Tilmiidzah

“…While all varieties showed optimal growth at 25°C, increasing temperatures from 25 to 30°C led to an increase in growth. …”
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Morale in Old Age and Its Association with Sociodemographic, Social, and Health-Related Factors in Different Age Groups by Marina Näsman, Johan Niklasson, Jan Saarela, Mikael Nygård, Birgitta Olofsson, Yngve Gustafson, Fredrica Nyqvist

“…Morale can be viewed as a future-oriented optimism or pessimism regarding challenges associated with aging and is closely related to subjective well-being. …”
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<i>Hermetia illucens</i> in the Process of Kitchen Waste Biodegradation: The Effect of Different Approaches to Waste Storage on the Microbiological Profile and Nutritional Paramete... by Zuzana Mašková, Juraj Medo, Eduard Kolesár, Dana Tančinová, Eva Ivanišová, Dana Urminská, Lukáš Hleba, Jana Urminská, Monika Mrvová, Zuzana Barboráková

“…These findings emphasize the importance of refrigerated, closed storage to optimize bioconversion, improve larval nutritional value, and minimize microbiological hazards.…”
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Development and Characterization of Lyophilized Chondroitin Sulfate-Loaded Solid Lipid Nanoparticles: Encapsulation Efficiency and Stability by Marta E. Bustos Araya, Anna Nardi Ricart, Ana C. Calpena Campmany, Rafel Prohens, Montserrat Miñarro Carmona

“…Two formulations (SLN-1 and SLN-2) were produced and optimized by evaluating critical physicochemical properties such as particle size, zeta potential, encapsulation efficiency (EE%), and stability. …”
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Betatrophin Acts as a Diagnostic Biomarker in Type 2 Diabetes Mellitus and Is Negatively Associated with HDL-Cholesterol by Min Yi, Rong-ping Chen, Rui Yang, Xian-feng Guo, Jia-chun Zhang, Hong Chen

“…ROC curve analysis identified betatrophin as a potent diagnostic biomarker for T2DM. The optimal cut-off point of betatrophin concentration for predicting T2DM was 501.23 pg/mL. …”
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An Enhanced Second-Order Terminal Sliding Mode Control Based on the Super-Twisting Algorithm Applied to a Five-Phase Permanent Magnet Synchronous Generator for a Grid-Connected Win... by Ben ouadeh Douara, Abdellah Kouzou, Ahmed Hafaifa, Jose Rodriguez, Mohamed Abdelrahem

“…Furthermore, the proposed hybrid control allows optimizing the power extraction and boosting the WECS’s efficiency. …”
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A global gross primary productivity of sunlit and shaded canopies dataset from 2002 to 2020 via embedding random forest into two-leaf light use efficiency modelZenodo by Zhilong Li, Ziti Jiao, Ge Gao, Jing Guo, Chenxia Wang, Sizhe Chen, Zheyou Tan

“…First, the TL-LUE model was optimized by considering the seasonal differences in the clumping index on a global scale (TL-CLUE). …”
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A Review on Diffusion Bonding between Titanium Alloys and Stainless Steels by De-feng Mo, Ting-feng Song, Yong-jian Fang, Xiao-song Jiang, Charles Q. Luo, Machael D. Simpson, Zhi-ping Luo

“…For diffusion bonding of a titanium alloy and a stainless steel without an interlayer, the optimized temperature is in the range of 800–950°C for a period of 60–120 min. …”
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Exploring influencing factors of healthy lifestyles in rural area among older adults with diabetes based on socioecological model by Yudong Miao, Xinran Li, Zhanlei Shen, Dongfang Zhu, Junwen Bai, Jingbao Zhang, Ruizhe Ren, Dan Guo, Clifford Silver Tarimo, Jinxin Cui, Mingyue Zhen, Jiajia Zhang, Yalin Song

“…The government should further optimize medical insurance policies to facilitate patients in adopting healthier lifestyles choices.…”
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Advanced surgical techniques and considerations in carotid body tumor management: insights from a cohort study by Farooq Ahmad Ganie, Masarat-ul Gani, Hakeem Zubair Ashraf, Shahbaz Bashir, Iqra Nazir Naqash, Mudasir Hamid Bhat, Shadab Maqsood, Altaf Hussain Mir, Mohd Iqbal Dar

“…Conclusion Surgical resection stands as the optimal therapeutic approach for managing CBTs. Once the diagnosis of CBT is confirmed, prompt surgical intervention should be pursued. …”
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The Evaluation of Thermodynamics and Environmental Impact of Waste Heat Recovery System Using Alternative Refrigerants by Aisyah Nyayu, Mukhtar Ariyadi Hifni, Ayu Putri Pratiwi Ilham, Sugiyanto, Fuadi Robith

“…This research provides insights into optimizing energy recovery from diesel engine waste heat and advancing sustainable energy solutions.…”
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The Human Mesenchymal Stromal Cell-Derived Osteocyte Capacity to Modulate Dendritic Cell Functions Is Strictly Dependent on the Culture System by Sara Trabanelli, Federico La Manna, Marco Romano, Valentina Salvestrini, Michele Cavo, Marilena Ciciarello, Roberto M. Lemoli, Antonio Curti

“…In vitro differentiation of mesenchymal stromal cells (MSC) into osteocytes (human differentiated osteogenic cells, hDOC) before implantation has been proposed to optimize bone regeneration. However, a deep characterization of the immunological properties of DOC, including their effect on dendritic cell (DC) function, is not available. …”
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Maturation of the biofloc system in Penaeus vannamei culture under different salinities and its effects on the microbial communities by Shaikha Y. Al-Sayegh, Victor Torres Rosas, Ponnumony Vethamony, Nor Azman Kasan, Hon Jung Liew, Mhd Ikhwanuddin, Zulfa Ali Al Disi, Hadil Elsayed, Jassim A. Al-Khayat

“…The results further highlight the significance of preserving a varied and well-balanced bacterial community in biofloc aquaculture systems to optimize nitrification and water quality control.…”
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The world’s most venomous spider is a species complex: systematics of the Sydney funnel-web spider (Atracidae: Atrax robustus) by Stephanie F. Loria, Svea-Celina Frank, Nadine Dupérré, Helen M. Smith, Braxton Jones, Bruno A. Buzatto, Danilo Harms

“…Although no human fatalities have occurred since the development of antivenom in the 1980s, antivenom for Sydney funnel-web spiders might be optimized by considering biological differentiation at the species level.…”
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The Simulation of a Surface Plasmon Resonance Metallic Grating for Maximizing THz Sensitivity in Refractive Index Sensor Application by Asmar Sathukarn, Chia Jia yi, Sakoolkan Boonruang, Mati Horprathum, Khwanchai Tantiwanichapan, Kiattiwut Prasertsuk, Chayut Thanapirom, Woraprach Kusolthossakul, Kittipong Kasamsook

“…., a filling factor and a grating depth, are optimized to increase the sensor sensitivity and sharpen the resonance dip. …”
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Slowly Delivered Icariin/Allogeneic Bone Marrow-Derived Mesenchymal Stem Cells to Promote the Healing of Calvarial Critical-Size Bone Defects by Tianlin Liu, Xin Zhang, Yuan Luo, Yuanliang Huang, Gang Wu

“…In in vitro cellular experiments, icariin at optimal concentration (10−6 mol/L) could significantly upregulate the osteogenesis- and angiogenesis-related genes and proteins, such as Runx2, ALP, osteocalcin, vascular endothelial growth factors, and fibroblast growth factors, as well as the mineralization of BMSCs. …”
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