Personalized medicine: An alternative for cancer treatment by Devendra Singh, Vinay Kumar Dhiman, Minakshi Pandey, Vivek Kumar Dhiman, Avinash Sharma, Himanshu Pandey, Sunil Kumar Verma, Rajeev Pandey

“…Precision medicine, often known as personalized medicine, is a new cancer treatment technique that focuses on tailoring medication to each patient's specific genetic, biochemical, and lifestyle factors. The goal is to optimize tumor response while minimizing therapy side effects, resulting in improved patient care and quality of life. …”
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Three-dimensional dynamics of mesothelin-targeted CAR.CIK lymphocytes against ovarian cancer peritoneal carcinomatosis by Federica Galvagno, Valeria Leuci, Annamaria Massa, Chiara Donini, Ramona Rotolo, Sonia Capellero, Alessia Proment, Letizia Vitali, Andrea Maria Lombardi, Valentina Tuninetti, Lorenzo D’Ambrosio, Alessandra Merlini, Elisa Vigna, Giorgio Valabrega, Luca Primo, Alberto Puliafito, Dario Sangiolo

“…Therefore, a comprehensive experimental model is crucial to optimize CAR-cell therapies in such a peculiar environment. …”
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5-Fluorouracil-β-Cyclodextrin conjugates:Linker strategies to enhance the anticancer efficacy and reduce the side effects by Liangliang Hu, Ting Meng, Davies Marabada, Zhichao Jin, Qing Huang, Shijie Wei, Zhizhong Wang

“…Future designs of linker can be optimized for greater efficiency.…”
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Gate-to-gate life cycle assessment of lithium-ion battery recycling pre-treatment by Anna Pražanová, Michael Fridrich, Jan Weinzettel, Vaclav Knap

“…Moreover, the study highlights the effectiveness of optimized recycling practices in alleviating environmental burdens. …”
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Towards climate-resilient conservation: Integrating genetics and environmental factors in determining adaptive units of a xeric shrub by Yong-Zhi Yang, Pei-Wei Sun, Chong-Yi Ke, Min-Xin Luo, Jui-Tse Chang, Chien-Ti Chao, Run-Hong Gao, Pei-Chun Liao

“…ENM identified the central-east and west-north regions as optimal habitats, while GF analysis revealed seed and breeding zones based on 1637 climate-adaptive SNPs, indicating significant genetic differentiation linked to temperature and precipitation. …”
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Cross-Cultural Adaptation and Validation of a Surgical Neonatal Nursing Workload Tool for an Italian Context: The Italian Winnipeg Surgical Complex Assessment of Neonatal Nursing N... by Emanuele Buccione, Floriana Pinto, Alessio Lo Cascio, Viola Palumbo, Kerry Hart, Allison Marchuk, Jessica-Lynn Walsh, Alexandra Howlett, The Italian Neonatal Nursing Workload Study Group, Laura Rasero, Davide Ausili, Stefano Bambi

“…There remain notable gaps in the current evidence regarding clinical complexity classification and related staffing adjustment, limiting the capacity for optimal staffing practices. This study aimed to adapt and validate the Winnipeg Surgical Complex Assessment of Neonatal Nursing Needs Tool (WANNNT-SC) for an Italian context to allow the assessment of newborns admitted to NICUs. …”
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Advancing Alzheimer's Therapy: Computational strategies and treatment innovations by Jibon Kumar Paul, Abbeha Malik, Mahir Azmal, Tooba Gulzar, Muhammad Talal Rahim Afghan, Omar Faruk Talukder, Samar Shahzadi, Ajit Ghosh

“…Through computational simulations, researchers can predict drug efficacy, optimize lead compounds, and facilitate personalized medicine approaches. …”
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What are the respiratory health research priorities in Alberta, Canada? A stakeholder consultation by Michael K Stickland, Sachin R Pendharkar, Jananee Rasiah, Joanna E MacLean, Heather Sharpe, Lisa Cerato, Darlene Derech, Lisa Guirguis, Kathleen Hayward, Tara Lohmann, Elizabeth Manafo, Janice Paskey, Mark Rimkus, Syeda Kinza Rizvi, Gerry Robinson, Brent Seefried, Zeeyaan Somani, Mindy Tindall, Harissios Vliagoftis, Kathy Hayward

“…At the inperson workshop, the Steering Committee identified 17 research topics as priority areas for respiratory and sleep research in Alberta.Conclusion A stakeholder-led research prioritisation process identified optimal clinical management/follow-up, equitable access to services, and management of social, psychological and mental health issues related to respiratory/sleep health as priority research areas.…”
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A comparative performance analysis of machine learning models for compressive strength prediction in fly ash-based geopolymers concrete using reference data by Muhammad Kashif Anwar, Muhammad Ahmed Qurashi, Xingyi Zhu, Syyed Adnan Raheel Shah, Muhammad Usman Siddiq

“…This study provides valuable insights for optimizing concrete mix designs, enhancing the performance and sustainability of FAGP, and contributes to the broader understanding of cementitious materials, fulfilling both industrial and environmental goals.…”
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Enhancing customer value co-creation through online brand interactivity: A comparative analysis of search-hedonic and experience-hedonic products by Rae Secioria, Adi Zakaria Afiff, Sri Rahayu Hijrah Hati, Muhammad Gunawan Alif

“…These insights underscore the importance of customizing brand interactivity strategies according to product characteristics to optimize customer value co-creation, particularly within the hedonic product market.…”
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Flux Synthesis of A‐site Disordered Perovskite La0.5M0.5TiO3 (M═Li, Na, K) Nanorods Tailored for Solid Composite Electrolytes by Tao Wang, Jiyoung Ock, X. Chelsea Chen, Fan Wang, Meijia Li, Matthew S. Chambers, Gabriel M. Veith, Lauren B. Shepard, Susan B. Sinnott, Albina Borisevich, Miaofang Chi, Amit Bhattacharya, Raphaële J. Clément, Alexei P Sokolov, Sheng Dai

“…According to a literature survey, the optimal LLTO filler should possess the following characteristics: i) a single‐crystal structure to minimize grain boundaries; ii) a small particle size to increase the filler/polymer interface area; iii) a 1D morphology for efficient interface channels; and iv) cubic symmetry to facilitate rapid bulk Li+ diffusion within the filler. …”
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Ferromagnetic Nickel as a Sustainable Reducing Agent for Tin–Lead Mixed Perovskite in Single‐Junction and Tandem Solar Cells by Doyun Im, Passarut Boonmongkolras, Yeonghun Yun, Sung Woong Yang, Sunwoo Kim, Jungchul Yun, Rajendra Kumar Gunasekaran, You‐Hyun Seo, Nam Joong Jeon, Gill Sang Han, Sangwook Lee

“…The unique bandgap tunability of halide perovskites enables optimal tandem configurations of wide‐bandgap (WBG) and NBG subcells. …”
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Liquid biopsy approaches to capture tumor evolution and clinical outcomes during cancer immunotherapy by Susan Scott, Mark Sausen, Valsamo Anagnostou, Jennifer Jackson, Vincent Lam, Joseph C Murray, Lavanya Sivapalan, Jenna Vanliere Canzoniero, Blair Landon, Benjamin P. Levy

“…These efforts highlight the emerging role of liquid biopsies in selecting patients for cancer immunotherapy, monitoring therapeutic efficacy, determining the optimal duration of treatment and ultimately guiding treatment selection and sequencing. …”
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Design of a Cost-Effective Ultrasound Force Sensor and Force Control System for Robotic Extra-Body Ultrasound Imaging by Yixuan Zheng, Hongyuan Ning, Eason Rangarajan, Aban Merali, Adam Geale, Lukas Lindenroth, Zhouyang Xu, Weizhao Wang, Philipp Kruse, Steven Morris, Liang Ye, Xinyi Fu, Kawal Rhode, Richard James Housden

“…The system integrates patient-to-robot registration, automated scanning path planning, and multi-sensor data fusion, allowing the robot to autonomously locate the patient, target the region of interest, and maintain optimal contact force during scanning. Validation was conducted using an ultrasound-compatible abdominal aortic aneurysm (AAA) phantom created from patient CT data and healthy volunteer testing. …”
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Reliability of an Inertial Measurement System Applied to the Technical Assessment of Forehand and Serve in Amateur Tennis Players by Lucio Caprioli, Cristian Romagnoli, Francesca Campoli, Saeid Edriss, Elvira Padua, Vincenzo Bonaiuto, Giuseppe Annino

“…The statistical analysis showed moderate and strong correlations, suggesting possible applications in assessing and optimizing specific aspects of the technique, like the player’s distance to the ball in the forehand or the toss in the serve. …”
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Adjuvant treatments for locally advanced differentiated thyroid cancer: a nationwide survey in Japan by Terufumi Kawamoto, Koichi Yasuda, Yoshinori Ito, Sadamoto Zenda, Katsuyuki Sakanaka, Naoto Shikama, Naoki Nakamura, Takashi Mizowaki

“…Future clinical trials will need to optimize EBRT for these patients.…”
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Study on freeze-thaw resistance and pore structure deterioration of fly ash reactive powder concrete based on low-field NMR relaxation by Dehong Wang, Hongji Zhang, Pang Chen, Yanzhong Ju, Peng Guo

“…The results demonstrate that an appropriate cement replacement with FA can fill the internal pores of the matrix and fully react with Ca(OH)2 for secondary hydration, significantly reduce the number of harmful pores in RPC and optimize the pore size distribution, thus inhibiting the generation of cracks during the freeze-thaw cycle. …”
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Synthesis and Spatial Structure of 3-Phenylacrylic Acid Octahydroquinolizin-1-Ylmethyl Ester and 2-(Octahydroquinolizin-1-Ylmethyl)Isoindole-1,3-Dione by Zh.S. Nurmaganbetov, O.A. Nurkenov, S.D. Fazylov, D.M. Turdybekov, Ye.V. Minayeva, G. Khabdolda, A.M. Ibraybekova, Zh.S. Tilla, K.M. Turdybekov

“… The reactions of lupinine alkaloid and its chlorine derivative with cinnamoyl chloride and 2-K-isoindole-1,3-dione were investigated to obtain 3-phenylacrylic acid octahydroquinolizin-1-ylmethyl ester and 2-(octahydroquinolizin-1-ylmethyl)isoindole-1,3-dione, respectively. The optimal conditions for carrying out the aforementioned reactions were determined, taking into account the nature of the solvent and medium. …”
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Quantitative Evaluation of the Effectiveness of Erbium Glass Laser Therapy for Acne Scars by Wiktoria Odrzywołek, Anna Deda, Dagmara Kuca, Małgorzata Bożek, Krzysztof Makarski, Sławomir Wilczyński

“…The Antera 3D system and high-frequency ultrasound device demonstrated high efficacy in capturing subtle changes, supporting its value in clinical applications for optimizing treatment parameters.…”
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Surface Modifications of Layered Perovskite Oxysulfide Photocatalyst Y2Ti2O5S2 to Enhance Visible‐Light‐Driven Water Splitting by Xizhuang Liang, Junie Jhon M. Vequizo, Lihua Lin, Xiaoping Tao, Qiulian Zhu, Mamiko Nakabayashi, Daling Lu, Hiroaki Yoshida, Akira Yamakata, Takashi Hisatomi, Tsuyoshi Takata, Kazunari Domen

“…Importantly, it is also possible to construct a Z‐scheme overall water splitting system using the optimized Y2Ti2O5S2 in combination with surface‐modified BiVO4 in the presence of [Fe(CN)6]3−/4−, yielding a solar‐to‐hydrogen energy conversion efficiency of 0.19%. …”
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