Navigating the neurovascular maze of trigeminal neuralgia by Devyansh Nimodia, MBBS, Pratapsingh Hanuman Parihar, MD, Sakshi Dudhe, MBBS, Ravishankar Patil, MD, Paritosh N. Bhangale, MBBS, Rishitha Kotla, MBBS

“…Magnetic resonance imaging (MRI) is the optimal modality for elucidating TN aetiology. Precise preoperative detection of neurovascular conflict enhances surgical efficiency and minimizes operative time. …”
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Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation by Chunxiang Lu, Aoxiang Jin, Chuang Gao, Hao Qiao, Huazhen Liu, Yi Zhang, Wenbin Sun, Shih-Mo Yang, Yuanyuan Liu

“…Through simulation and experimental validation, we rapidly optimized microwell size and the coating process. We successfully formed three types of spheroids—human immortalized epidermal cells (HaCaTs), umbilical cord mesenchymal stem cells (UC-MSCs), and human osteosarcoma cells (MG63s)—on the chip. …”
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SAR Radiometric Cross-Calibration Based on Multiple Pseudoinvariant Calibration Sites With Extensive Backscattering Coefficient Range by Yongsheng Zhou, Xiang Chen, Qiang Yin, Fei Ma, Fan Zhang

“…This article proposes an optimized method for selecting PICS for SAR radiometric cross-calibration to address these issues. …”
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A Comprehensive Analysis of Moist Versus Non‐Moist Dressings for Split‐Thickness Skin Graft Donor Sites: A Systematic Review and Meta‐Analysis by Chun‐Yee Ho, Hsuan‐Yu Chou, Szu‐Han Wang, Ching‐Yu Lan, Victor Bong‐Hang Shyu, Chih‐Hao Chen, Chia‐Hsuan Tsai

“…The study highlights the need for further research to address existing limitations and refine recommendations for optimal wound care interventions.…”
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Protease and <i>Bacillus coagulans</i> Supplementation in a Low-Protein Diet Improves Broiler Growth, Promotes Amino Acid Transport Gene Activity, Strengthens Intestinal Barriers,... by Junlong Niu, Yingying Qiao, Xiaopeng Yang, Xiaoshuang Chen, Hongfei Li, Yongpeng Guo, Wei Zhang, Zhixiang Wang

“…Both PRO and PAB diets significantly enhanced the expression of amino acid transport genes and tight junction genes (<i>p</i> < 0.05) and optimized the composition of the intestinal microbiota. …”
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The Effects of Ankle Joint Position on Deep Peroneal Nerve Latencies by Mohamed Hussein El-Gendy, Mahmoud Salah Abd El-Fattah, Mohamed Magdy El Meligie, Efrem Kentiba, Yasser Ramzy Lasheen

“…These findings provide preliminary evidence that may help optimize ankle positioning in electrodiagnostic testing. …”
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Prevalence, Diagnostics and Treatment of Small Intestinal Bacterial Overgrowth in the Clinical Practice in Southern Federal District of the Russian Federation by N. V. Korochanskaya, I. L. Kliaritskaya, S. N. Serikova, A. V. Tkachev, M. V. Koroleva, M. A. Basenko

“…Aim: to optimize the provision of medical care to patients with small intestinal bacterial overgrowth (SIBO) in the Southern Federal District based on clarification of data on the epidemiology of the syndrome (disease), unification of approaches to diagnostics and treatment.Materials and methods. …”
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High-integrity diffusion bonding of laser powder bed fused, forged, and rolled Ti–6Al–4V alloys by Seoyeon Jeon, Hyunjong Ha, Dong Jun Lee, Hyeonil Park, Yong Nam Kwon, Hyunjoo Choi, Hyokyung Sung

“…Extended bonding durations led to β phase coarsening and thickened, elongated α′ laths in LPBFed materials, negatively impacting their mechanical properties. Optimal bonding was achieved at 900 °C for 2 h under 4 MPa, with bonding ratios exceeding 97%. …”
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MAEMC-NET: a hybrid self-supervised learning method for predicting the malignancy of solitary pulmonary nodules from CT images by Tianhu Zhao, Tianhu Zhao, Yong Yue, Hang Sun, Jingxu Li, Yanhua Wen, Yudong Yao, Wei Qian, Yubao Guan, Shouliang Qi, Shouliang Qi

“…The model performs best on medical images with a 50% mask ratio, showing a 1.4% increase in accuracy compared to the optimal 75% mask ratio on natural images.DiscussionThe proposed MAEMC-NET effectively distinguishes between benign and malignant solitary pulmonary nodules and holds significant potential to assist radiologists in improving the diagnostic accuracy of PGN and SLA.…”
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Enhanced MICP for Soil Improvement and Heavy Metal Remediation: Insights from Landfill Leachate-Derived Ureolytic Bacterial Consortium by Armstrong Ighodalo Omoregie, Fock-Kui Kan, Hazlami Fikri Basri, Muhammad Oliver Ensor Silini, Adharsh Rajasekar

“…Experimental conditions identified yeast extract-based media as most effective for bacterial growth, urease activity, and calcite formation compared to nutrient broth and brown sugar media. Optimal MICP conditions, at pH 8–9 and 30 °C, supported the most efficient biomineralization. …”
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A Novel Method to Evaluate the Effect of Slope Blasting under Impact Loading by Wenhai Zhou, Zhenbao Li, Xin Wu, Shujiang Wang, Yaru Lv, Xiaoming Lou, Chaofei Du, Rui Liang

“…The validity index of the maximum membership principle is used to assess the accuracy of the evaluation results of two algorithms, and a relevant approaching degree is chosen to optimize the results. The entire evaluation process selects eleven indicators to form an evaluation set, including the boulder yield, root rate, flying distance of flyrock, explosive consumption, postcracking distance, detonator unit consumption, vibration velocity, loose coefficient, cast distance, throw rate, and blasted volume per meter of hole. …”
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Hypergravity as a Possible Way of Bone Tissue Engineering in Osteoblastic Differentiation from Mesenchymal Stem Cells: A Systematic Review by Wisnu Sudrajad, Andre Erica Indrawan, Devangga Kusuma, Bagus Wibowo Soetojo, Heri Suroto

“…This study revealed that a gravity force of 30G and a culture duration of 7 to 14 days are the most optimal combination for inducing osteoblastic differentiation in MSCs.…”
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Performance evaluation of bio/chemical leaching solution and nano catalyst in upgrading and enhancing oil recovery by Mohammad Hossein Shabani, Parya Torkaman, Hamidreza Farshadfar, Arezou Jafari, Seyyed Mohammad Mousavi

“…The comprehensive evaluation of catalytic performance under dynamic conditions provides valuable insights into optimizing recovery processes and underscores the dual economic and environmental benefits of this approach.…”
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Using artificial intelligence based language interpretation in non-urgent paediatric emergency consultations: a clinical performance test and legal evaluation by Julia Brandenberger, Ian Stedman, Noah Stancati, Karen Sappleton, Sarathy Kanathasan, Jabeen Fayyaz, Devin Singh

“…Establishing legal and policy frameworks for language interpretation in healthcare is crucial, alongside addressing funding and data security concerns, to optimize the use of AI-based translation tools in healthcare contexts.…”
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Co-occurrence of a Mullerian anomaly and Kallmann syndrome: A case report by Lea C. George, Rebecca Gendelman, Anat Chemerinski, Pierre Lespinasse, Inessa A. Goldman, Sara Morelli

“…The possibility of co-occurring pathologies should always be considered to provide optimal care to the patient.…”
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Effect of low frequency magnetic field (LFMF) on germination and vigour of accelerated aged radish (Raphanus sativus L.) seeds by Xia Xianzong, Zająс-Woźnialis Anna, Padula Gregorio, Kubisz Leszek, Hołubowicz Roman

“…The results showed that LFMF treatment has improved the germination and vigour of the AA radish seeds. The optimal seed treatment conditions of the cultivars were different: for the cultivar C - 20 μT, 120 min. and for the cultivar SBK - 20 μT, 60 min. …”
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A Weighted Bayesian Kernel Machine Regression Approach for Predicting the Growth of Indoor-Cultured Abalone by Seung-Won Seo, Gyumin Choi, Ho-Jin Jung, Mi-Jin Choi, Young-Dae Oh, Hyun-Seok Jang, Han-Kyu Lim, Seongil Jo

“…The proposed model not only improves prediction accuracy compared to baseline methods, but also provides actionable insights into the environmental dynamics that optimize abalone growth. These findings underscore the potential of advanced machine learning techniques in enhancing aquaculture practices and offer a robust framework for managing complex, multi-variable systems in sustainable farming.…”
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New Optic Nerve Sonography Quality Criteria in the Diagnostic Evaluation of Traumatic Brain Injury by Ibrahim Soliman, Garrett G. R. J. Johnson, Lawrence M. Gillman, Frederick A. Zeiler, Fahad Faqihi, Waleed Tharwat Aletreby, Abdullah Balhamar, Nasir Nasim Mahmood, Shahzad Ahmad Mumtaz, Abdulrahman Alharthy, Christos Lazaridis, Dimitrios Karakitsos

“…New sonographic quality criteria to optimize optic nerve sheath diameter (ONSD) measurements were suggested. …”
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Timing of Tracheotomy in Mechanically Ventilated Critically Ill Morbidly Obese Patients by Ahmad Alhajhusain, Ailia W. Ali, Asif Najmuddin, Kashif Hussain, Masooma Aqeel, Ali A. El-Solh

“…Background. The optimal timing of tracheotomy and its impact on weaning from mechanical ventilation in critically ill morbidly obese patients remain controversial. …”
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Structural basis of FpGalNase and its combination with FpGalNAcDeAc for efficient A-to-O blood group conversion by Meiling Zhou, Kaishan Luo, Chao Su, Yan Sun, Zuyan Huang, Shuo Ma, Xun Gao, Jiwei Wang, Chen Zhang, Pengcheng Han, Guoqiu Wu

“…In this study, we investigated two enzymes from Flavonifractor plautii, N-acetylgalactosamine deacetylase (FpGalNAcDeAc) and galactosaminidase (FpGalNase), which demonstrate synergistic activity in efficiently converting A-type RBCs to O-type. We optimized treatment conditions, achieving over 99% conversion in just five minutes using phosphate buffer saline and a 16 nM enzyme concentration. …”
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