Direct Hot Solid–Liquid Extraction (DH-SLE): A High-Yield Greener Technique for Lipid Recovery from Coffee Beans by Daliane Cláudia de Faria, Maria Eliana Lopes Ribeiro de Queiroz, Fábio Junior Moreira Novaes

“…A 3³ full factorial design was used to perform direct hot solid–liquid extractions in 4 mL vials, varying the ground grains and solvent ratios, temperatures, and times. An optimal condition resulted in an extractive yield statistically equivalent to Soxhlet, without variation in the composition of the oil fatty acids determined by GC-MS after hole oil transesterification. …”
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Design and simulation of a 5 KW solar-powered hybrid electric vehicle charging station with a ANN–Kalman filter MPPT and MPC-based inverter control for reduced THD by Youness Hakam, Hajar Ahessab, Ahmed Gaga, Mohamed Tabaa, Benachir El Hadadi

“…By integrating a Kalman filter with Artificial Neural Networks (ANN) for Maximum Power Point Tracking (MPPT), the system optimizes energy capture from photovoltaic (PV) panels, even in severe weather conditions and partial shading. …”
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Advancing <i>Glycyrrhiza glabra</i> L. Cultivation and Hairy Root Transformation and Elicitation for Future Metabolite Overexpression by Negin Afsharzadeh, Renate Paltram, Arne Jungwirth, Leila Tabrizi, Vahideh Nazeri, Hadi Kalantari, Heidi Halbwirth, Leila Samiei, Hester Sheehan, Majid Shokrpour

“…These findings provide valuable insights into conditions for optimal seed germination and hairy root transformation. …”
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Exploring drivers and prevention strategies for sexual violence among adolescent girls and young women in Kicukiro, Rwanda by Wongani Patricia Kawonga, Sam M. Livingstone, Augustine Ndaimani, Jean Pierre Sibomana, Tsion Yohannes Waka, Maxwell Mhlanga, Andrew Mclellan

“…Data was analyzed using thematic analysis to identify key drivers and potential prevention strategies.ResultsFour themes emerged: (1) empowering mentorship programs, (2) tiered drivers of sexual violence, (3) optimizing violence-mitigating resources, and (4) interference with judicial processes. …”
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Comparing the Global Tariff and Actual Costs of Surgeries at Imam Khomeini Hospital Affiliated with Kermanshah University of Medical Sciences by Jamil Sadeghifar, Nasim Eyvani, GHasem Rajabi Vasukolai, Naser Farhamand Moghadam, Shahram Ekhtyari

“…Background and purpose: Creating sustainable income, enhancing economic perspectives, optimizing and managing costs, and generating revenue in the health system—especially in hospitals, which are primary providers of medical services—are critically important. …”
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A Reliability-Based Design of Africa-Birch Timber-Reinforced Concrete Beams by Alhassan Aliyu Abdulrazaq, Uwemedimo Nyong Wilson, John Engbonye Sani, Ibrahim Rabiu

“…The flexural strength and deflection analysis reveals Steel-AB outperforming other sections and was found to be optimal under various loading conditions. For flexure, Steel-AB achieved a safety index (β) of 1.98 and probability of failure (Pf) of 0.0238 at a span length of 10,000mm and effective depth of 400mm. …”
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Research progress of network-based interventions on self-care ability of patients with chronic heart failure (慢性心力衰竭患者自我护理能力网络干预的研究进展) by ZHAI Kaijing (翟凯静), ZHANG Yuqing (张雨晴), LIU Wei (刘薇), QIAO Zhihui (乔志桧), FANG Cui (方璀), FU Conghan (付聪晗)

“…The aim of this study is to ensure that these interventions meet the needs of different individuals to optimize the self-care management of chronic heart failure. …”
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Contingent Negative Variation and Working Memory Maintenance in Adolescents with Low and High Motor Competencies by Sebastian Ludyga, Christian Herrmann, Manuel Mücke, Christian Andrä, Serge Brand, Uwe Pühse, Markus Gerber

“…Thus, high performers on complex motor tasks seem to rely more on a proactive control strategy, which is optimal in tasks with high working memory demands.…”
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Numerical Simulation of Bubble Coalescence and Break-Up in Multinozzle Jet Ejector by Dhanesh Patel, Ashvinkumar Chaudhari, Arto Laari, Matti Heiliö, Jari Hämäläinen, Kishorilal Agrawal

“…Designing the jet ejector optimally is a challenging task and has a great impact on industrial applications. …”
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Maximizing E-Tailers’ Sales Volume through the Shipping-Fee Discount and Product Recommendation System by Yan Guo, Xiaonan Hu, Yu Zou, Shouwei Li, Wenchuan Cheng, Zhiyong Li

“…The proposed model first determines the optimal shipping-fee discount to attract customers and then establishes the most suitable product recommendation list to encourage customers to spend more money on other products. …”
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Islet organoids: a new hope for islet transplantation in diabetes by Xuemei Yu, Chengkong Liu, Zheng Kuang, Siyuan Song, Limin Tian, Yi Wang, Yi Wang

“…While each approach addresses specific challenges in islet transplantation, further research is needed to optimize scalability, immune compatibility, and long-term functionality. …”
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Concurrent Effects of Plyometric Interval Training Implemented in Physical Education Lessons on Adolescent Power and Endurance: An Analysis of Responder Prevalence by Dawid Koźlenia, Katarzyna Kochan-Jacheć, Jarosław Domaradzki

“…However, the effects varied across individuals and were generally small, highlighting the need to optimize the intervention to achieve more pronounced results tailored to individual characteristics.…”
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Intelligent IoT-Based Network Clustering and Camera Distribution Algorithm Using Reinforcement Learning by Islam T. Almalkawi, Rami Halloush, Mohammad F. Al-Hammouri, Alaa Alghazo, Loiy Al-Abed, Mohammad Amra, Ayooub Alsarhan, Sami Aziz Alshammari

“…Our proposed approach initially uses a geometric distributed network clustering algorithm that optimizes camera placement based on the camera Field of View (FoV). …”
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Quantitative Detection of miRNA-21 Expression in Tumor Cells and Tissues Based on Molecular Beacon by Qingxin Liu, Jialong Fan, Chuang Zhou, Liqun Wang, Bin Zhao, Haibin Zhang, Bin Liu, Chunyi Tong

“…With the tool of molecular beacons which can hybridize specifically with target miRNA-21 and generate fluorescence signal change, this paper develops a direct, simple, and rapid method for miRNA-21 detection with detection limit of 0.5 nM. Under the optimal conditions, the method was used to detect the expression of miRNA-21 in tumor cells and tissues. …”
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Convolutional Neural Decoder for Surface Codes by Hyunwoo Jung, Inayat Ali, Jeongseok Ha

“…In addition, we introduce how to optimize the hyperparameters in the CNN, according to the lattice structure of a given surface code. …”
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Clinical impact of direct rotational atherectomy in patients with complex coronary artery lesions by Kyusup Lee, Ji-hoon Jung, Woojin Kwon, Dae-Won Kim, Mahn-Won Park, Ik Jun Choi, Jae-Hwan Lee, Yong Hoon Yoon, Jang Hoon Lee, Sang Rok Lee, Pil Hyung Lee, Seung-Whan Lee, Ki Dong Yoo, Kyeong Ho Yun, Hyun-Jong Lee, Sung-Ho Her

“…Abstract Owing to limited data on the optimal timing of rotational atherectomy (RA), we sought to evaluate the clinical impact of the early application of the RA strategy. …”
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Standardization of Micropropagation for Four Hybrids of <i>Coffea arabica</i> Through Direct Somatic Embryogenesis by Marileydi Zuta-Puscan, Jegnes Benjamín Meléndez-Mori, Eyner Huaman-Huaman, Yoiner Kalin Lapiz-Culqui, Reyna Stefani Mego-Pérez, Manuel Oliva-Cruz

“…In addition, the germination and conversion of embryos into plantlets are more efficient in the woody plant medium (WPM), while rooting is optimized using indole-3-butyric acid (IBA) concentrations between 1 mg L⁻¹ and 3 mg L⁻¹, regardless of the hybrid. …”
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Experimental Study and Application of LASC Foamed Concrete to Create Airtight Walls in Coal Mines by Duo Zhang, Weifeng Wang, Jun Deng, Hu Wen, Xiaowei Zhai

“…In the LASC filling materials, the optimal volume ratio of foam dosage to gel slurry is 2. …”
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Two Approaches to Cognitive Evaluation: Assessing the Strengths and Limitations of GPCOG and ACE-III by Magdalena Mąka, Dominik Sikora, Piotr Oleksy, Adam Zając, Karol Zieliński, Łukasz Papież, Ewa Góralczyk, Jakub Kamiński, Bartosz Buczkowski, Dagmara Wochnik

“…Conclusions : ACE-III is optimal for detailed evaluations in specialized settings, while GPCOG excels in rapid primary care screening. …”
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The effect of auditory rhythm on the temporal allocation of visual attention in aging by Zhihan Xu, Juan Huang, Yuxuan Shen, Yanna Ren, Yulin Gao, Ting Guo

“…IntroductionIsochronous rhythm has been shown to induce temporal expectation, allocated attention to specific points in time to optimize behavioral performance, both within a single modality and across different modalities, in younger adults. …”
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