Development of Starter Cultures for Precision Fermentation of Kombucha with Enriched Gamma-Aminobutyric Acid (GABA) Content by Geun-Hyung Kim, Kwang-Rim Baek, Ga-Eun Lee, Ji-Hyun Lee, Ji-Hyun Moon, Seung-Oh Seo

“…To produce the GABA-fortified kombucha, selected single strains of <i>Acetobacter pasteurianus</i>, <i>Lactiplantibacillus plantarum</i>, and <i>Saccharomyces cerevisiae</i> were mixed and used as starter cultures. By optimizing the inoculation ratios and initial sugar concentration, a functional kombucha enriched with acetic acid, lactic acid, and GABA was successfully produced. …”
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Leiomyosarcoma of the Right Gonadal Vein: Review of the Approach and Prognostic in a Rare Case by Noa de la Fuente, Manuel Rodríguez Blanco, Gemma Cerdán, Antonio Moral, Vicenç Artigas

“…Although it was not used in this patient, the standard procedure for optimal survival is resection en bloc.…”
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Over‐The‐Top Technique for ACL Reconstruction: Advantages, Disadvantages, and Postoperative Complications by Haocheng Du, Lin Li, Ziwen Qin, Jiang Guo, Xintao Zhang

“…Currently, femoral tunnel failure is the most common cause of ACL reconstruction failure, which can lead to less than optimal postoperative performance of the ACL and a higher likelihood of needing a revision. …”
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Endoscopic Resection for Small Rectal Neuroendocrine Tumors: Comparison of Endoscopic Submucosal Resection with Band Ligation and Endoscopic Submucosal Dissection by Byoung Wook Bang, Jin Seok Park, Hyung Kil Kim, Yong Woon Shin, Kye Sook Kwon, Joon Mee Kim

“…There is no consensus so far regarding the optimal endoscopic method for treatment of small rectal neuroendocrine tumor (NET). …”
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Differential between-therapist effects in more versus less standardized therapies for depression by Anuj H. P. Mehta, Michael J. Constantino, Jack J. M. Dekker, Alice E. Coyne, Averi N. Gaines, Henricus L. Van, Jaap Peen, Frank J. Don, Ellen Driessen

“…Moreover, they highlight treatment standardization as one possible determinant of effectiveness differences, which necessitates determining for which therapists such standardization is most important for optimizing their patient’s outcomes.…”
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Bearing Fault Diagnosis Based on Collaborative Representation Using Projection Dictionary Pair by Dan Ma, Yixiang Lu, Yushun Zhang, Hua Bao, Xueming Peng

“…Second, under the similarity assumption, a dictionary pair learning strategy is employed to build an overcomplete dictionary pair, which is used to realize an optimal representation of the vibration signal. Meanwhile, the sparse constraint is also taken into account during dictionary training to enhance the robustness of the classification. …”
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Structural, Morphological and Thermal Properties of Kenaf Microcrystalline Cellulose/Poly (Butylene Adipate-Co-Terephthalate) Films for Packaging Applications by Aatikah Meraj, Ahmad Safwan Ismail, Mohammad Jawaid

“…SEM makes it evident that addition of MCC to PBAT influences the surface morphology, with an optimal range promoting mechanical adherence through roughness. …”
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Molecular network analysis for detecting HIV transmission clusters: insights and implications by Yangyang Liu, Lichun Hua, Wenqian Wu, You Ge, Wei Li, Pingmin Wei

“…With an accuracy of 86.25%, the optimal parameter for the phylogenetic tree and gene distance approach was 90 + 0.045 substitution/loci. …”
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Towards Elimination of Mother-to-Child Transmission of HIV: The Impact of a Rapid Results Initiative in Nyanza Province, Kenya by Lisa L. Dillabaugh, Jayne Lewis Kulzer, Kevin Owuor, Valerie Ndege, Arbogast Oyanga, Evelyne Ngugi, Starley B. Shade, Elizabeth Bukusi, Craig R. Cohen

“…Many HIV-positive pregnant women and infants are still not receiving optimal services, preventing the goal of eliminating mother-to-child transmission (MTCT) and improving maternal child health overall. …”
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Leveraging machine learning and rule extraction for enhanced transparency in emergency department length of stay prediction by Waqar A. Sulaiman, Charithea Stylianides, Andria Nikolaou, Andria Nikolaou, Zinonas Antoniou, Ioannis Constantinou, Lakis Palazis, Anna Vavlitou, Theodoros Kyprianou, Theodoros Kyprianou, Efthyvoulos Kyriacou, Antonis Kakas, Antonis Kakas, Marios S. Pattichis, Andreas S. Panayides, Constantinos S. Pattichis, Constantinos S. Pattichis

“…By combining predictive analytics with interpretable rule-based methods, this research provides actionable insights for optimizing patient flow and resource allocation. The findings highlight the importance of transparency in machine learning applications for healthcare, paving the way for future improvements in model performance and clinical adoption.…”
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Shadi Park Renovation with Social Development Emphasis: A Case Study Halabja City, Iraq by Mihraban Othman Mustafa, Masoumeh Faraji, Zaniar Jamal Salih, Muhammed Saeed Rasheed

“…Shadi Park in Iraq is one of the regional urban parks; the lack of its design, as well as the wear and tear of some uses, lack of optimal lighting system and various uses by different age groups reduces the number of visits. …”
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Retrievals of water vapour and temperature exploiting the far-infrared: application to aircraft observations in preparation for the FORUM mission by S. Panditharatne, S. Panditharatne, S. Panditharatne, H. Brindley, H. Brindley, C. Cox, R. Siddans, R. Siddans, J. Murray, J. Murray, L. Warwick, S. Fox

“…<p>We present the extension of the Rutherford Appleton Laboratory (RAL) Infrared Microwave Sounding (IMS) optimal estimation retrieval scheme to include the use of far-infrared channels in preparation for the upcoming Far-infrared Outgoing Radiation Understanding and Monitoring (FORUM) mission. …”
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Core Cross-linked Star Polymers for Temperature/pH Controlled Delivery of 5-Fluorouracil by Elizabeth Sánchez-Bustos, José M. Cornejo-Bravo, Angel Licea-Claverie

“…The prepared core cross-linked star polymers represent advanced drug delivery vehicles optimized for 5-FU with potential application in cancer treatment.…”
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Q-learning global path planning for UAV navigation with pondered priorities by Kevin B. de Carvalho, Hiago de O.B. Batista, Leonardo A. Fagundes-Junior, Iure Rosa L. de Oliveira, Alexandre S. Brandão

“…This study introduces a novel approach to offline path planning in static environments, utilizing Q-learning as its foundation. The method optimizes three pivotal factors: path length, safety, and energy consumption. …”
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Forecasting basal area increment in forest ecosystems using deep learning: A multi-species analysis in the Himalayas by P. Casas-Gómez, J.F. Torres, J.C. Linares, A. Troncoso, F. Martínez-Álvarez

“…Our methodology includes rigorous hyperparameter tuning to optimize the Deep Learning models’ architecture. We evaluate the models’ performance across 15 species in the Himalayan region, individually and collectively, using temperature and precipitation data as predictors. …”
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MacSyFinder v2: Improved modelling and search engine to identify molecular systems in genomes by Néron, Bertrand, Denise, Rémi, Coluzzi, Charles, Touchon, Marie, Rocha, Eduardo P.C., Abby, Sophie S.

“…We introduce a more intuitive and comprehensive search engine to identify all the best candidate systems and sub-optimal ones that respect the models’ constraints. …”
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Systematic and Empirical Study of the Dependence of Polyphenol Recovery from Apricot Pomace on Temperature and Solvent Concentration Levels by Dina Cheaib, Nada El Darra, Hiba N. Rajha, Richard G. Maroun, Nicolas Louka

“…The response surface methodology showed that the optimal extraction condition was reached with 50% ethanol/water at 75°C giving a total phenolic content (TPC) of 9.8 mg GAE/g DM, a flavonoids content (FC) of 8.9 mg CE/g DM, a tannin content (TC) of 4.72 mg/L, and an antiradical activity (AA) of 44%. …”
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External Load Variability in Elite Futsal: Positional Demands and Microcycle Structuring for Player Well-Being and Performance by Héctor Gadea-Uribarri, Elena Mainer-Pardos, Ainhoa Bores-Arce, Rafael Albalad-Aiguabella, Sergio López-García, Carlos Lago-Fuentes

“…By providing reference values from elite contexts, this study offers practical insights for S&C coaches to optimize microcycles. Furthermore, it contributes to workload management strategies within sport science and public health frameworks, promoting sustainable performance and athlete wellness in futsal.…”
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Primary Spinal Germ Cell Tumors: A Case Analysis and Review of Treatment Paradigms by Joshua J. Loya, Henry Jung, Caroline Temmins, Nam Cho, Harminder Singh

“…We advocate biopsy followed by local radiation, with or without adjuvant chemotherapy, as the optimal treatment for these tumors. Histological findings have prognostic value if syncytiotrophoblastic giant cells (STGCs) are found, which are associated with a higher rate of recurrence. …”
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Assessing Human Factors in Virtual Reality Environments for Industry 5.0: A Comprehensive Review of Factors, Metrics, Techniques, and Future Opportunities by Oscar Escallada, Ganix Lasa, Maitane Mazmela, Ainhoa Apraiz, Nagore Osa, Hien Nguyen Ngoc

“…This paradigm shift underscores the importance of collaboration between humans and advanced technologies with a focus on optimizing efficiency, safety, and worker skill development. …”
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