Effect of jet flow control in front of the leading bogie on the aerodynamic drag and underbody slipstream of high-speed trains by Sha Huang, Zhi-Wei Li, Wen-Jing Peng, Jin-Rong Lin, Zun-Di Huang, Guang-Zhi Zeng

“…Bogies are significant contributors to the aerodynamic resistance of high-speed trains, making them key areas of consideration for flow control and optimization. This study applied an air jet slot positioned in front of the leading bogie to explore its effectiveness in reducing the train’s aerodynamic resistance under Reynolds number (Re) of 2.64 × 106. …”
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Designing blade wheels for microturbine plants based on prototypes by A. S. Pugachuk, D. V. Muller, A. V. Chernyshev

“…In this article it is said about gasdynamic and strength optimization of turbine impellers. The offered method allows to reduce stresses in a turbine impeller during an operating mode without changing of useful gasdynamic characteristics. …”
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POMA-C: A Framework for Solving the Problem of Precise Anesthesia Control Under Incomplete Observation Environment in Low-Income Areas by Yide Yu, Huijie Li, Dennis Wong, Anmin Hu, Jian Huo, Yan Ma, Yue Liu

“…The framework employs the POMCPOW (Partially Observable Monte Carlo Planning with Observation Weighting) algorithm, which integrates Monte Carlo Tree Search (MCTS) and particle filtering to estimate the patient’s true physiological state and guide optimal anesthetic decisions. Through comprehensive ablation experiments—where key observation dimensions are systematically reduced to simulate missing data—POMA-C demonstrates significantly higher decision accuracy and cumulative reward optimization compared to methods like Q-learning and human expertise, even in data-constrained environments. …”
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Tibial acceleration alone is not a valid surrogate measure of tibial load in response to stride length manipulation by Jean Tu, Olivia L. Bruce, W. Brent Edwards

“…Motion capture, force platform, and tibial acceleration data were directly measured, and ankle joint contact forces were estimated using an inverse-dynamics-based static optimization routine. Results: In general, peak axial tibial accelerations (p < 0.001) as well as axial (p < 0.001) and resultant (p < 0.001) ankle joint contact forces increased with stride length. …”
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CFD modelling and simulation of anaerobic digestion reactors for energy generation from organic wastes: A comprehensive review by Muhammad Usman Farid, Indiana A. Olbert, Andreas Bück, Abdul Ghafoor, Guangxue Wu

“…This approach contributes to minimize the experimental costs while optimizing the reactor configurations in less time. …”
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Effect of French Press Brewing on the Sensory Quality of Robusta Coffee Produced in Hainan by LIU Di, LAO Fei, DONG Wenjiang, YU Xinxin

“…Single factor experiments and response surface methodology were used jointly for optimization of four processing parameters based on consumer preference, and the correlation between consumer preference and sensory characteristics and flavor components was analyzed by quantitative sensory description, gas chromatography-mass spectrometry (GC-MS), and ultra performance liquid chromatography (UPLC). …”
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CalciumZero: a toolbox for fluorescence calcium imaging on iPSC derived brain organoids by Xiaofu He, Yian Wang, Yutong Gao, Xuchen Wang, Zhixiong Sun, Huixiang Zhu, Kam W. Leong, Bin Xu

“…It streamlines the entire analysis process, offering full automation with just one click after parameter optimization. In addition, it includes supplementary features to statistically evaluate the impact on disease etiology and the detection of drug candidate effects on calcium activities. …”
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Capture of 3D Human Motion Pose in Virtual Reality Based on Video Recognition by Qiang Fu, Xingui Zhang, Jinxiu Xu, Haimin Zhang

“…In the case of using all optimization algorithms, the accuracy rate is higher than 90%, and the final recognition accuracy rate is also higher than 90%. …”
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A Huge Innovation in Diagnosis of Obstructive Sleep Apnea Syndrome: With an Artificial Intelligence-Based Algorithm, Obstructive Sleep Apnea Syndrome Can Now Be Diagnosed With Pulm... by Seval Bulut Eris, Mehmet Recep Bozkurt, Omer Eris, Cahit Bilgin

“…The models obtained by hyperparameter optimization and cross-validation were tested with unseen data, and their performance was evaluated using seven different criteria. …”
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Deep Learning Framework for Advanced De-Identification of Protected Health Information by Ahmad Aloqaily, Emad E. Abdallah, Rahaf Al-Zyoud, Esraa Abu Elsoud, Malak Al-Hassan, Alaa E. Abdallah

“…Unlike prior studies that often unify Bi-LSTM and CRF layers, our approach focuses on the individual design, optimization, and hyperparameter tuning of both the Bi-LSTM and CRF components, allowing for precise model performance improvements. …”
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Super High Contrast USPIO-Enhanced Cerebrovascular Angiography Using Ultrashort Time-to-Echo MRI by Liam Timms, Tianyi Zhou, Ju Qiao, Codi Gharagouzloo, Vishala Mishra, Rita Maria Lahoud, John W. Chen, Mukesh Harisinghani, Srinivas Sridhar

“…However, its potent T2∗ relaxivity limits achievable T1-weighted positive contrast and leads to artifacts in standard MRI protocols. Optimization of protocols for ferumoxytol deployment is necessary to realize its potential. …”
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Undoped ruthenium oxide as a stable catalyst for the acidic oxygen evolution reaction by Jiayi Tang, Daqin Guan, Hengyue Xu, Leqi Zhao, Ushtar Arshad, Zijun Fang, Tianjiu Zhu, Manjin Kim, Chi-Wen Pao, Zhiwei Hu, Junjie Ge, Zongping Shao

“…While considerable progress has been made in designing doped Ru oxides and composites to improve stability, the uncertainty in true failure mechanism in acidic oxygen evolution reaction inhibits their further optimization. This study reveals that proton participation capability within Ru oxides is a critical factor contributing to their instability, which can induce catalyst pulverization and the collapse of the electrode structure. …”
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A Cost-Effective and Robust Cell-Based Bioassay Method for Evaluating the Bioactivity of Trastuzumab-like Antibodies by Pooja Bharali, Subhash Chand, Harish Chander

“…<b>Results:</b> The SKBR3 cell line was found to express the HER2 receptors significantly higher in comparison to the other cell lines, and it was thereby selected for further bioassay optimization. The biological activity of trastuzumab was determined using the inhibition of proliferation (IOP) assay on the SKBR3, which was optimized based on the parameters of cell seeding density, drug dilution range, and incubation time, and it was further validated as per the compendial guidelines and found valid for the parameters of specificity, accuracy (% relative bias = 0.0067%), precision (repeatability: % GCV = 1.21%), linearity (R2 = 0.99), and range (50% to 200%). …”
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A 3D Porous Gelatin-Alginate-Based-IPN Acts as an Efficient Promoter of Chondrogenesis from Human Adipose-Derived Stem Cells by Sorina Dinescu, Bianca Galateanu, Eugen Radu, Anca Hermenean, Adriana Lungu, Izabela Cristina Stancu, Dana Jianu, Tudorita Tumbar, Marieta Costache

“…Recent CTE approaches rely on optimal cell-scaffold interactions, which require a great deal of optimization. …”
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Design of a mammography X-ray image classification assistant system adapted to Chinese population by SUN Changjin, TONG Fei, WU Yi

“…Aiming at the problem that the Chinese population data are not ideal in the performance test of the open dataset training model， an optimization strategy based on the sliding window adjustment mechanism was implemented in combination with the characteristics of Chinese population data. …”
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Global, regional, and national survey on burden and Quality of Care Index (QCI) of orofacial clefts: Global burden of disease systematic analysis 1990-2019. by Ahmad Sofi-Mahmudi, Erfan Shamsoddin, Sahar Khademioore, Yeganeh Khazaei, Amin Vahdati, Marcos Roberto Tovani-Palone

“…Gender difference showed a converging trend from 1990 to 2019 (optimal gender disparity ratio (GDR): 123 vs. 163 countries), and the GDR showed a move toward optimization (between 0.95 and 1.05) in the better and worse parts of the world.…”
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Solving Nonlinear Energy Supply and Demand System Using Physics-Informed Neural Networks by Van Truong Vo, Samad Noeiaghdam, Denis Sidorov, Aliona Dreglea, Liguo Wang

“…The neural network model is then trained, and the parameters are identified and optimized to achieve a more accurate solution. The solutions obtained from the neural network for this problem are equivalent when we compare and evaluate them against the Runge–Kutta numerical method of order 5(4) (RK45). …”
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Clinical efficacy of various resuscitation fluids in the management of sepsis in postoperative surgical and trauma patients: a systematic review and meta‑analysis by Yongjie Wang, Kewu Chen, Xiaolu Li, Jianing Guan

“…Still, there are significant ambiguities regarding the most suitable fluid type that would ensure optimization of patient outcomes. Aim: The aim of this systematic review and meta-analysis was to assess the clinical effectiveness of different resuscitation fluids for sepsis management in critically hypotensive patients. …”
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Changes in Vowel Articulation with Subthalamic Nucleus Deep Brain Stimulation in Dysarthric Speakers with Parkinson’s Disease by Vincent Martel Sauvageau, Joël Macoir, Mélanie Langlois, Michel Prud’Homme, Léo Cantin, Johanna-Pascale Roy

“…Results suggest that STN DBS may improve articulation in dysarthric speakers with PD, in terms of range of movement. Optimization of the electrical parameters for each patient is important and may lead to improvement in speech fine motor control. …”
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Effects of Dietary Protein to Lipid Ratio and Insect Meal on Growth Performance, Feed Utilization, and the Gut Microbiome of Lake Whitefish (Coregonus clupeaformis) by Rebecca Lawson, Yubing Chen, Junyu Zhang, Marcia A. Chiasson, Jennifer Ellis, Dominique Bureau, Richard D. Moccia, David Huyben

“…However, further work on targeted breeding and genetic selection of broodstock, together with diet optimization, is needed to improve the growth performance and nutrient utilization in order to enable an effective, economical, and environmentally sustainable culture of lake whitefish.…”
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