Alginate-based encapsulation of porcine placenta extract: Preparation, enteric sustained release, biological activities, and stability by Anukul Taweechaipaisankul, Nutthanit Thumrongsiri, Walailuk Chonniyom, Paweena Dana, Prattana Tanyapanyachon, Monthira Rattanatayarom, Wannapa Chinchoosak, Nattika Saengkrit

“…Taken together, microbead fabrication, especially F2, is the optimal formula for pPEs, showing the potential to be applied as a prospective carrier of pPEs for oral administration.…”
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A non-aseptic bioprocess for production and recovery of 2,3-butanediol via conversion of crude glycerol and corn steep liquor at pilot-scale by Dimitris Karayannis, Nikos Angelou, Gabriel Vasilakis, Ioannis Charisteidis, Alexandros Litinas, Seraphim Papanikolaou

“…The production and recovery of 2,3-butanediol (BDO) through biodiesel derived glycerol valorization by Klebsiella oxytoca ACA-DC 1581 was holistically optimized with regard to the efficiency and cost of the bioprocess. …”
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Surgical stabilization of rib fractures (SSRF): the WSES and CWIS position paper by Giacomo Sermonesi, Riccardo Bertelli, Fredric M. Pieracci, Zsolt J. Balogh, Raul Coimbra, Joseph M. Galante, Andreas Hecker, Dieter Weber, Zachary M. Bauman, Susan Kartiko, Bhavik Patel, SarahAnn S. Whitbeck, Thomas W. White, Kevin N. Harrell, Daniele Perrina, Alessia Rampini, Brian Tian, Francesco Amico, Solomon G. Beka, Luigi Bonavina, Marco Ceresoli, Lorenzo Cobianchi, Federico Coccolini, Yunfeng Cui, Francesca Dal Mas, Belinda De Simone, Isidoro Di Carlo, Salomone Di Saverio, Agron Dogjani, Andreas Fette, Gustavo P. Fraga, Carlos Augusto Gomes, Jim S. Khan, Andrew W. Kirkpatrick, Vitor F. Kruger, Ari Leppäniemi, Andrey Litvin, Andrea Mingoli, David Costa Navarro, Eliseo Passera, Michele Pisano, Mauro Podda, Emanuele Russo, Boris Sakakushev, Domenico Santonastaso, Massimo Sartelli, Vishal G. Shelat, Edward Tan, Imtiaz Wani, Fikri M. Abu-Zidan, Walter L. Biffl, Ian Civil, Rifat Latifi, Ingo Marzi, Edoardo Picetti, Manos Pikoulis, Vanni Agnoletti, Francesca Bravi, Carlo Vallicelli, Luca Ansaloni, Ernest E. Moore, Fausto Catena

“…The expert recommendations clarify current evidences on SSRF indications, timing, operative planning, approaches and techniques, with the aim to guide clinicians in optimizing the management of rib fractures, to improve patient outcomes and direct future research.…”
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Comparative Efficacy and Safety of Targeted Therapies for Chronic Thromboembolic Pulmonary Hypertension: A Systematic Review and Network Meta-Analysis by Yusi Chen, Fang Li, Jun Luo, Jingyuan Chen, Peng Luo, Jiang Li

“…NMA revealed that riociguat was ranked first as the most optimized therapy for ameliorating the 6-minute walk distance with a probability of 80.4%. …”
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Machine vision-based detection of key traits in shiitake mushroom caps by Jiuxiao Zhao, Jiuxiao Zhao, Wengang Zheng, Wengang Zheng, Yibo Wei, Yibo Wei, Qian Zhao, Qian Zhao, Jing Dong, Jing Dong, Xin Zhang, Xin Zhang, Mingfei Wang, Mingfei Wang

“…It achieved an per-image best threshold (OIS) rate of 93.5%. Also, it reached an Optimal Dynamic Stabilization (ODS) rate of 96.3%. …”
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Pollen contamination and mating structure in maritime pine (Pinus pinaster Ait.) clonal seed orchards revealed by SNP markers by Bouffier, Laurent, Debille, Sandrine, Alazard, Pierre, Raffin, Annie, Pastuszka, Patrick, Trontin, Jean-François

“…Genetic analyses were based on an optimized set of 60 SNP markers and performed on 2,552 seedlings with Cervus software (likelihood inference methodology). …”
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Novel immune cross-talk between inflammatory bowel disease and IgA nephropathy by Qianqian Yan, Zihao Zhao, Dongwei Liu, Jia Li, Shaokang Pan, Jiayu Duan, Zhangsuo Liu

“…This study aimed to identify the optimal cross-talk genes, potential pathways, and mutual immune-infiltrating microenvironments between IBD and IgAN to elucidate the linkage between patients with IBD and IgAN. …”
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Study on Strength Variation of Permeable Concrete Based on Differential Calorimetry Method and Multi-Index Test by Sanqiang Yang, Meng Guo, Shichao Duan, Na Liu, Haonan Wu, Erxia Du, Meichen Liang

“…At 85°C, only one exothermic peak appeared, indicating that C3S hydration and ettringite formation process were completed at the same time in a relatively short time. (2) The optimal water-binder ratio of pervious concrete ranges from 0.24 to 0.30, and the optimal porosity ranges should be controlled within the range of 15%–25%. …”
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Primary small cell carcinoma of the esophagus: Comparison between a Chinese cohort and Surveillance, Epidemiology, and End Results (SEER) data by Qin Xiao, Haifan Xiao, Shuyu Ouyang, Jinming Tang, Baihua Zhang, Hui Wang

“…Abstract Background The optimal standard treatment for primary small cell carcinoma of the esophagus (SCCE) remains undetermined. …”
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Comparative efficacy and safety of 20 intravenous pharmaceutical intervention for prevention of etomidate-induced myoclonus: a systematic review and Bayesian network meta-analysis by Lu Chen, Lu Chen, Pengxiang Zhou, Pengxiang Zhou, Zhengqian Li, Ziyang Wu, Suodi Zhai, Suodi Zhai

“…ObjectiveTo compare the efficacy and safety of pharmaceutical interventions to prevent etomidate-induced myoclonus (EIM), providing the optimal intervention for clinical practice.MethodsPubMed, Embase, the Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, Chinese National Knowledge Infrastructure, WanFang database, and SinoMed database were searched from the inception to sixth May 2024. …”
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Simultaneous Determination of Over-the-Counter Pain Relievers in Commercial Pharmaceutical Products Utilizing Multivariate Curve Resolution-Alternating Least Squares (MCR-ALS) Mult... by Heba Shaaban, Ahmed Mostafa, Zahra Almatar, Reem Alsheef, Safia Alrubh

“…The optimized method was also compared with a reported HPLC method using paired t-test and F-ratio at 95% confidence level, and the results showed no significant difference regarding accuracy and precision. …”
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Acute Stroke in northern Portugal: outcomes and characteristics of patients in a Medical-Surgical Emergency Department by Sandra Domingues, Tiago Barros, João Correia, Arlindo Cruz, Nuno Araújo, Liliana Silva

“…Enhanced systematic data recording and new technologies are needed to optimize care. Future research should focus on long-term outcomes and quality-of-life measures. …”
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Designing supply chain scenarios and investigating how it affects relevant variables in the National Company of Southern Oil-bearing Regions by Amin Mirshekar, Ghanbar Amirnejad, Mohammad Hemati, Ali Kangarani Farahani

“…By simulating the system, it is possible to achieve its optimal level by parametrically changing this variable, and it can be continuously monitored and re-evaluated over time. …”
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A New Seamless Transfer Control Strategy of the Microgrid by Zhaoyun Zhang, Wei Chen, Zhe Zhang

“…The mode conversion controller is installed in microgrid and the control logic of master power is optimized for microgrid mode conversion. In the proposed scheme, master power is very important. …”
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The Canadian Multicentre MAC Treatment Study by Stephen D Shafran, The Canadian HIV Trials Network

“…While it is acknowledged thal MAC infection requires treatment with a combination of antimycobacterial drugs. the optimal regimen has not been defined. A Canadian Multicentre MAC Treatment Trial was proposed in 1990 and finally implemented in late 1992 via the Canadian HIV Trials Network with the assistance of 6 pharmaceutical companies. …”
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Parenteral Nutrition in Liver Resection by Carlo Chiarla, Ivo Giovannini, Felice Giuliante, Francesco Ardito, Maria Vellone, Agostino Maria De Rose, Gennaro Nuzzo

“…This is a peculiar topic because many patients do not need artificial nutrition, while several patients need it because of malnutrition and/or prolonged inability to feeding caused by complications. The optimal nutritional regimen to support liver regeneration, within other postoperative problems or complications, is not yet exactly defined. …”
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Effect of rare earth elements La and Ce on corrosion resistance of low alloy steel by Da Wei, Qing Li, Renzheng Zhu, Xiaojia Yang, Longfei Song, Guowei Yang, Xinyu Wang, Xuequn Cheng, Xiaogang Li

“…The mechanism of the effect of La and Ce on the corrosion resistance of low alloy steel was determined by wet/dry cyclic immersion test, combined with electrochemical analysis, morphology of corrosion products and phase analysis. Finally, the optimal amount of Rare earth elements was determined to improve the corrosion resistance of low alloy steel.…”
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Facial Involuntary Movements and Respiratory Failure in CANOMAD, Responsive to IVIG Therapy by Kate Johnson, Ashish Malkan, Mohamed Shaffi

“…Our patient was initially misdiagnosed with Miller Fisher Syndrome, highlighting the need for vigilance should neurological symptoms recur in patients initially diagnosed with a Guillain Barre variant. Moreover, the optimal treatment is unknown. This patient responded remarkably to intravenous immunoglobulin and has been maintained on this treatment, without further exacerbations.…”
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New Trends and Future Perspectives in the Diagnosis of Urothelial Carcinoma: A Comprehensive Review of the Literature by Mourmouris Panagiotis, Georgopoulos Ioannis, Klapsis Vasilleios, Pisiotis Nikolaos, Salmas Ioannis, Charamoglis Sotirios

“…In our review, we summarize all the available data concerning the contemporary technological novelties that include imaging, cytology, and endoscopic techniques in pursuit of finding the optimal combination of diagnostic tools that can provide better detection accuracy.…”
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New Niobium Capacitors with Stable Electrical Parameters by H. Zillgen, M. Stenzel, W. Lohwasser

“…We developed a new niobium capacitor which shows stable electrical values. By optimizing the structure of the dielectric and the cathodic layers as well as the process parameters we gained a capacitor which can be used up to 105 °C . …”
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