Pathophysiology of Portal Hypertension and Esophageal Varices by Hitoshi Maruyama, Osamu Yokosuka

“…The major therapeutic strategy of esophageal varices consists of primary prevention, treatment for bleeding varices, and secondary prevention, which are provided by pharmacological, endoscopic, interventional and surgical treatments. Optimal management of esophageal varices requires a clear understanding of the pathophysiology and natural history. …”
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Biological characterization of novel Escherichia coli O157:H7 phages and their bacteriostatic effects in milk and pork by Qinghai Ren, Qinghai Ren, Qinghai Ren, Zhiwei Wang, Yichen Ge, Yucui Huang, Wei Zhang, Chunxue Liu, Yubao Li, Shengliang Cao

“…The optimal MOIs of vB_EcoP_SD2 and vB_EcoP_SD6 was 0.1 and 0.01, and temperature range for maintaining activity was 4°C to 55°C. …”
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The growth of eel fed with different protein level and protein-energy ratio by Fitria Nawir, Nur Bambang Priyo Utomo, Tatag Budiardi

“…ABSTRACT   The study was aimed to determine the optimum dietary protein level and energy protein ratio which can optimize growth performance of the eel A. bicolor bicolor on nursery phase.  …”
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PENERAPAN PROJECT BASED LEARNING MODEL UNTUK MENINGKATKAN SIKAP ILMIAH MAHASISWA DALAM RANGKA MENGHADAPI ERA MERDEKA BELAJAR by Andik Purwanto, Desy Hanisa Putri, Dedy Hamdani

“…Thermodynamics subject learning often creates problems because it is not precise in choosing a learning model, so it is not able to optimize the learning process which in turn will cause the development of students' scientific attitudes to be less than optimal. …”
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Designing a Model for Implementing Digital Banking Policy Based on Using Big Data in Iranian Banking Industry by Rahmatollah Gholipour Souteh, Hamed Esmaeili Rad

“…It seeks to develop an optimal model for implementing such policies, with a special focus on the dimensions of policy implementation specific to digital banking. …”
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Characterization of RAP Signal Patterns, Temporal Relationships, and Artifact Profiles Derived from Intracranial Pressure Sensors in Acute Traumatic Neural Injury by Abrar Islam, Amanjyot Singh Sainbhi, Kevin Y. Stein, Nuray Vakitbilir, Alwyn Gomez, Noah Silvaggio, Tobias Bergmann, Mansoor Hayat, Logan Froese, Frederick A. Zeiler

“…Autocorrelative function (ACF) and partial ACF (PACF) plots of residuals verified the adequacy of these median optimal ARIMA models. The median of residuals indicates that ARIMA performed better with the higher-resolution data. …”
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Climate Change and Ecosystem Services of Florida’s Largest Water Body: Lake Okeechobee by Karl Havens

“…This 7-page fact sheet provides background, optimal and actual water levels, projected changes in South Florida climate and their effects on water levels in Lake Okeechobee, their effects on ecosystem services, and possible remedies. …”
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Short Bowel Syndrome: Surgical Therapy by W Donald Buie, Olin G Thurston, Richard N Fedorak

“…Some of these solutions, combined with optimal medical management, may represent the patient's only hope for survival without parenteral nutrition. …”
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An Orlicz-Besov Poincaré Inequality via John Domains by Hongyan Sun

“…Denote by B˙⁎α,ϕ(Ω) the intrinsic Orlicz-Besov space, where α∈R, ϕ is a Young function, and Ω⊂Rn is a domain. For α∈(-n,0) and optimal ϕ, via John domains, we establish criteria for bounded domains Ω⊂Rn supporting an Orlicz-Besov Poincaré inequality. …”
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Single domain antibody-scFv conjugate targeting amyloid β and TfR penetrates the blood–brain barrier and interacts with amyloid β by Rebecca Faresjö, Elisabet O. Sjöström, Tiffany Dallas, Magnus M. Berglund, Jonas Eriksson, Dag Sehlin, Stina Syvänen

“…Furthermore, our results suggest that a given bispecific TfR-binding fusion format has a window of “optimal” affinity where parenchymal delivery is adequate, while blood pharmacokinetics aligns with the desired application of the fusion protein.…”
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Production of Hydrophobic Microparticles at Safe-To-Inject Sizes for Intravascular Administration by Francisca L. Gomes, Francisco Conceição, Liliana Moreira Teixeira, Jeroen Leijten, Pascal Jonkheijm

“…., drugs, peroxides), providing an optimal solution for numerous biomedical purposes, such as drug delivery or oxygen therapeutics. …”
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Fabrication, In Vitro, and In Vivo Assessment of Eucalyptol-Loaded Nanoemulgel as a Novel Paradigm for Wound Healing by Anis Rehman, Muhammad Iqbal, Barkat A. Khan, Muhammad Khalid Khan, Bader Huwaimel, Sameer Alshehri, Ali H. Alamri, Rami M. Alzhrani, Deena M. Bukhary, Awaji Y. Safhi, Khaled M. Hosny

“…The results suggest that the formulated optimized dosage showed optimum stability, and it can be considered an effective wound healing alternative.…”
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Moringa oleifera seed meal as a sustainable fishmeal substitute: Growth and health implications for Cirrhinus mrigala by Sadia Tabassum, Syed Makhdoom Hussain, Shafaqat Ali, Pallab K. Sarker, Khalid A. Al-Ghanim, Lalarukh

“…Proximate body composition revealed optimal crude protein (74 %), crude fat (81 %), and gross energy (61 %) levels in fish fed the 10 % MOSM diet. …”
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Thinking on the Meteorological Services to Ensure the Development of a System for New Energy Sources by Yongchang ZHU, Xiaofeng ZHANG, Zhenghong CHEN, Dong YE, Juan TAN, Yong QIN, Zhaohui LIU, Zhiqi XU

“…[Conclusion] According to the requirements of a system for new energy sources construction, proposals are put forward from aspects such as optimizing the layout of meteorological services, improving service support capabilities, strengthening talent and cooperation mechanisms.…”
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Controls on the geotechnical properties of plastic-bonded pavement blocks produced by artisanal means in Bamenda, Cameroon by Bertrand Tatoh Aziwo, Moses Kuma Mbuh, Irene Bongsiysi Bame, Paul Venyite, Moyouwou Amadou Njoya, Fidelis Toke Ntam, M.V. Nsongka, Ndigui Billong

“…From the results, the geotechnical properties are influenced by nature and size of aggregate, type and amount of plastic-binder and production method. Finding the optimal plastic-binder content for a given aggregate and plastic type is key in achieving optimal geotechnical properties. …”
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Prediction of Final Phosphorus Content of Steel in a Scrap-Based Electric Arc Furnace Using Artificial Neural Networks by Riadh Azzaz, Mohammad Jahazi, Samira Ebrahimi Kahou, Elmira Moosavi-Khoonsari

“…These results demonstrate that the optimized ANN model offers accurate predictions for the steel final phosphorus content.…”
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Adaptive cognitive control in 4 to 7-year-old children and potential effects of school-based yoga-mindfulness interventions: an exploratory study in Italy by Lisa Toffoli, Giulia Stefanelli, Giulia Manca, Fiorella Del Popolo Cristaldi, Gian Marco Duma, Michele Guidi, Francesca Incagli, Luca Sbernini, Luca Sbernini, Vincenza Tarantino, Giovanni Mento, Giovanni Mento

“…Moreover, they successfully modulate interference control as a function of environmental contingencies, displaying more optimal conflict resolution when proactive control is engaged. …”
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Variation and simulation of tomato transpiration in a greenhouse under different ventilation modes by Jiankun Ge, Sen Wang, Xuewen Gong, Yuhao Zhu, Zihui Yu, Yanbin Li

“…Greenhouse ventilation is a critical factor in regulating internal microclimates, ensuring optimal crop growth, and improving water use efficiency in facility agriculture. …”
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An Effective Flocculation Method to the Kaolin Wastewater Treatment by a Cationic Polyacrylamide (CPAM): Preparation, Characterization, and Flocculation Performance by Badradine Zakaria Djibrine, Huaili Zheng, Moxi Wang, Shuang Liu, Xiaomin Tang, Sarfaraz Khan, Andrea Navarro Jimenéz, Li Feng

“…For PAD used as flocculant in kaolin wastewater treatment, the results confirmed that, at optimal conditions, the turbidity and the floc size d50 could reach to 5.9 NTU and 565.936 μm, respectively, at the optimal conditions (pH = 7.0 and dosage = 2 mg l−1). …”
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Development and validation of machine learning models for MASLD: based on multiple potential screening indicators by Hao Chen, Jingjing Zhang, Xueqin Chen, Ling Luo, Wenjiao Dong, Yongjie Wang, Jiyu Zhou, Canjin Chen, Wenhao Wang, Wenbin Zhang, Zhiyi Zhang, Yongguang Cai, Danli Kong, Yuanlin Ding

“…Ultimately, our study constructed the optimal MASLD risk prediction model using HOMA-IR, TyG-WC, age, AST, and ethnicity.…”
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