Targeting Acinetobacter baumannii resistance-nodulation-division efflux pump transcriptional regulators to combat antimicrobial resistance by Ruwani L. Wimalasekara, Dawn White, Ayush Kumar

“…Abstract Regulatory elements controlling gene expression fine-tune bacterial responses to environmental cues, including antimicrobials, to optimize survival. Acinetobacter baumannii, a pathogen notorious for antimicrobial resistance, relies on efficient efflux systems. …”
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Glucagon-like peptide-1 receptor agonists and type 1 diabetes: a potential game changer? by Ortal Resnick, Fernando Bril, Fernando Bril, Giovanna Beauchamp

“…This mini review explores the increasing prevalence of obesity in type 1 diabetes (T1D) and the challenges patients face in achieving optimal glycemic control with current treatments. …”
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Crucial role of pre-treatment in plastic photoreforming for precision upcycling by Xiandi Zhang, Wenhan Zu, Lawrence Yoon Suk Lee

“…By identifying key factors affecting reaction dynamics, we aim to establish optimized frameworks for plastic photoreforming and enhance sustainable waste management, highlighting opportunities for improvement and innovation.…”
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A weak Galerkin finite element method for parabolic singularly perturbed convection-diffusion equations on layer-adapted meshes by Suayip Toprakseven, Seza Dinibutun

“…Error estimates for semi-discrete and fully-discrete schemes were presented, and the optimal order of uniform convergence has been obtained. …”
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Synthesis of Multicriteria Controller by Means of Fuzzy Logic Approach by Andrew Lozynskyy, Lyubomyr Demkiv

“…For fuzzification process, classical both linear and nonlinear membership functions are used. To find optimal values of membership function’s parameters, genetic algorithm is used. …”
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Unilateral Ureteric Endometriosis at the Pelvic Brim Resulting in Complete Loss of Renal Function by Keisuke Tanaka, Akwasi A. Amoako, Katherine Gray, David Baartz

“…Greater awareness of ureteric endometriosis and a multidisciplinary approach in the management is essential to achieve optimal outcomes. We present an atypical case of right ureteric obstruction due to endometriosis at the pelvic brim resulting in complete loss of renal function and necessitating nephroureterectomy.…”
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Worldwide Sports Injury Prevention by Luciana D Mendonça, Joke Schuermans, Evi Wezenbeek, Erik Witvrouw

“…The number one goal of the sports physical therapist is to make sure that the athlete is in optimal shape to perform, but with a minimal risk for developing an injury at the same time. …”
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Value of triglyceride glucose-body mass index in predicting nonalcoholic fatty liver disease in individuals with type 2 diabetes mellitus by Xiaoyi Qian, Wenwen Wu, Boyang Chen, Simin Zhang, Chunmei Xiao, Long Chen, Jun Chen, Jun Chen, Lingli Ke, Meian He, Xiulou Li, Xiulou Li, Xiulou Li

“…The ROC curve was used to assess the predictive efficacy of the TyG-BMI index for NAFLD in T2DM patients.ResultsBMI predicted the development of NAFLD in T2DM patients with an area under the receiver operating characteristic (ROC) curve of 0.792 (95% CI 0.757-0.828), and the optimal cutoff value was 25.22, with 72.2% sensitivity and 71.6% specificity; The area under the receiver operating characteristic (ROC) curve of the TyG index to predict the development of NAFLD in patients with T2DM was 0.755 (95% CI 0.716-0.794), and the optimal cutoff value was 8. 945, with a sensitivity of 80.1% and a specificity of 59.2%; The area under the receiver operating characteristic (ROC) curve of TyG-BMI index to predict the development of NAFLD in T2DM patients was 0.852, (95% CI 0.822-0.882), and the optimal cutoff value was 227.385, with a sensitivity and specificity of 80.1% and 59.2%, respectively.ConclusionsThe TyG-BMI index is a significant predictor of comorbid NAFLD in T2DM patients and provides better screening performance than BMI alone. …”
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Astrobiology with Robotic Telescopes at CAB by Luis Cuesta, M. Teresa Eibe, Aurora Ullán, Antonio Pérez-Verde, Jorge Navas

“…These telescopes, equipped with advanced technology, optimized control programs, and optical and technical characteristics adequate for this purpose, are ideal to make the observations that are required to carry out these programs. …”
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Multidrug-Resistant Tuberculosis: Treatment and Outcomes of 93 Patients by Sarah K Brode, Robert Varadi, Jane McNamee, Nina Malek, Sharon Stewart, Frances B Jamieson, Monica Avendano

“…There is scanty evidence regarding optimal management of MDR TB. The majority of Canadian cases of MDR TB are diagnosed in Ontario; most are managed by the Tuberculosis Service at West Park Healthcare Centre in Toronto. …”
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Introduction to Organic Crop Production by Danielle D. Treadwell

“… Organic farming can generally be described as a method of production that utilizes non-synthetic inputs and emphasizes biological and ecological process to improve soil quality, manage soil fertility, and optimize pest management. This revised 16-page fact sheet is written for commercial producers who are transitioning to or beginning organic production. …”
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FEATURES OF THE IMPACT OF ORGANIZATIONAL CULTURE ON THE INDUSTRIAL ENTERPRISES EFFICIENCY by D. Shkolnyi, I. Groshev

“…To achieve the best results, it is necessary to work on optimizing the company’s culture. The functions of the organizational culture, its type, the nature of the interaction between employee and organizational elements have been considered and the estimated components of the efficiency of the organizational culture have been identified. …”
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Joseph Loxton Rawbon, the "Master Restorer" by Cyndie Lack

“…A colourful character with bombastic flair, his numerous enterprises, however limited in their success, exemplify the boundless optimism of the Industrial Age and open a small window onto the history of Toronto's early cultural development through to the Second World War.  …”
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Therapeutic Drug Monitoring in the Treatment of Active Tuberculosis by Aylin Babalik, Sharyn Mannix, Denis Francis, Dick Menzies

“…Therapeutic drug monitoring ensures optimal dosing while aiming to reduce toxicity. However, due to the high costs and complexity of testing, therapeutic drug monitoring is not routinely used in the treatment of individuals with active tuberculosis, despite the efficacy demonstrated in several randomized trials. …”
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Parallelization in combining the SOM and Sammon's mapping by Gintautas Dzemyda, Olga Kurasova, Virginijus Marcinkevičius

“…The results of investigation allow us to optimize the number of the SOM training epochs, the number of the SOM training blocks, and the number of Sammon’s iterations. …”
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Amniotic Fluid Embolism Treated with Veno-Arterial Extracorporeal Membrane Oxygenation by Robert Gitman, Bradlee Bachar, Byron Mendenhall

“…The use of echocardiography proved to be an invaluable tool to help guide treatment and optimal duration of ECMO in the face of severe coagulopathy.…”
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Reduction of Fuel Consumption Normal in Regenerative Furnaces ith Moving and Blown-Through Layer while Producing Lime from CaCO₃ by V. А. Sednin, A. P. Nesenchuk, A. G. Kozhevnikov, I. V. Melnikov

“…Formulation of the problem concerning optimal numerical modeling of CaCO3 roasting with the purpose to obtain highly qualitative final product CaO for metallurgical electric arc furnaces is given in the paper.Modeling results in reduction of CaCO3 overheating at the stage of roasting. …”
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Controlled Filtered Poisson Processes by Mario Lefebvre

“…To obtain the value function, and hence the optimal control, a non-linear integro-differential equation must be solved, subject to the appropriate boundary conditions. …”
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The Time Discontinuous H1-Galerkin Mixed Finite Element Method for Linear Sobolev Equations by Hong Yu, Tongjun Sun, Na Li

“…The existence and uniqueness of the solutions are proved, and the optimal H1-norm error estimates are derived. We get high accuracy for both the space and time variables.…”
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Polarization Stable Triband Thin Square-Shaped Metamaterial Absorber by M. L. S. N. S. Lakshmi, S. Prasad Jones Christydass, S. Kannadhasan, K. Anguraj, Jyotir Moy Chatterjee

“…The parameters of the designed absorber are optimized. The simulated results show that it has good absorption rate and polarization stability. …”
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